Boris Pasche

Boris Pasche

Chair and Professor Department of Oncology School of Medicine / President and CEO Karmanos Cancer Institute

Boris Pasche

Office Address

Karmanos Cancer Institute
Hudson-Webber Cancer Research Center
4100 John R.
Detroit, MI 48201

Office Phone



Dr. Pasche’s career spans over 30 years, in which he’s held numerous executive leadership positions. He has shown great success in growing and expanding an NCI-designated comprehensive cancer center’s program resulting in more funding, and has strengthened and re-organized cancer research programs leading to NCI core grant renewal. Dr. Pasche is an elected member of the American Society for Clinical Investigation and the American Clinical and Climatological Association. He is the recipient of Ohio State University Human Cancer Genetics Program Commemorative Medal and the Jeanik M. Littelfield-American Association for Cancer Research Award in Metastatic Colon Cancer Research. Dr. Pasche is a member of the American Association of Cancer Research, American Association of Clinical Oncology, American Society of Hematology, American Society of Human Genetics, The Bioelectromagnetics Society, and the Eastern Cooperative Oncology Group and the American College of Radiology Imaging Network (ECOG-ACRIN) Cancer Research Group. He also served as an associate editor for JAMA (Journal for American Medical Association), a peer-reviewed medical journal, for over a decade.



(1986) MD, Karolinska Institute, Solna, Sweden
(1987) MD, University of Lausanne, Lausanne, Switzerland
(1989) PhD, Karolinska Institute, Solna, Sweden

Postgraduate Training

(1989-1992) Research fellow in the laboratory of Dr. Joseph Loscalzo, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School. Boston, MA
(1996-2000) Research fellow in the laboratory of Dr. Joan Massagué, Cell Biology Program, Howard Hughes Medical Institute and Sloan-Kettering Institute for Cancer Research. New York, NY

Graduate Medical Training

(1992-1994) Internship and Residency in Medicine, The New York Hospital Cornell Medical Center. New York, NY
(1994-1997) Fellowship in Hematology/Oncology, Memorial Sloan-Kettering Cancer Center and the New York Hospital, Cornell University Medical College. New York, NY

Research Interests

As an experienced hematologist and medical oncologist, Dr. Pasche’s clinical specialties are in treating gastrointestinal malignancies and hereditary cancer. His research focuses on cancer susceptibility and new therapies. In 2023, a medical device Dr. Pasche co-invented, TheraBionic P1, was approved by the FDA for the treatment of advanced hepatocellular carcinoma, the most common type of liver cancer.


 Boris Pasche, MD, PhD, FACP - Publications

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