Clinical Electrophysiology lab
Lab
2751 E. Jefferson
Detroit, MI 48207
Negative symptoms are the most difficult to treat and most disabling among all the manifestations of schizophrenia. Medications, this far, has not shown significant efficacy
against these symptoms. Rapid Repetitive Transcranial Magnetic Stimulation (rTMS) has an excitatory effect on the brain tissue. As a prefrontal lobe deficit has been postulated
to play a major role in the pathophysiology of negative symptoms, it is theoretically possible that rTMS may be able to activate this brain region resulting in decreased negative
symptoms. The current proposal is the initial exploration of this possibility. Five subjects with schizophrenia and predominance of negative symptoms will be included in this
exploratory phase.
of Sensory Gating