Wayne State University/Perinatology Research Branch - Labor and Delivery Important Points and Discoveries

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IMPORTANT POINTS & DISCOVERIES

Intra-amniotic infection and/or inflammation can lead to the Fetal Inflammatory Response Syndrome (FIRS) and is a major mechanism of disease responsible for numerous perinatal and infant morbidities including, neurologic handicap and cerebral palsy
Characterization of the role of adipokines in normal pregnancy, preeclampsia, small for gestational age neonates, gestational diabetes, pyelonephritis, and spontaneous preterm labor
Identification of placental growth hormone in the fetal circulation with novel implications for fetal growth
The use of both cervical length and fetal fibronectin improves the prediction of preterm delivery in patients with preterm labor and intact membranes
Failure of physiologic transformation of the spiral arteries in patients with preterm labor and intact membranes