| Annual Report |
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| 2000-2001 | |
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Features: Academia and Industry Working Together for Biomedical Advances WSU Considered Model Program in Prenatal Genetic Analysis WSU Gets Early Access to Corning Technologies Dr. Joan Dunbar: Research Matchmaker Best Oncology Practices Standardized by Innovative Solutions Freezing the Deadly Spread of Cancer Combining Technology and Expertise to Discover New Genes in Epilepsy General Motors Supports Prevention Program Cell Therapy Center Advances Immunotherapies for Clinical Application |
Pediatrics Chair: Alan Gruskin, MD
Division of
Allergy/Immunology/Rheumatology Cuesta IA, Moore EC, Rabah R, Bawle EV: Blau syndrome in an African American Family. J Clin Rheum 6(1):30-34, 2000.
Books, Chapters and Reviews Secord EA, in Internal Medicine Review, emedicine.com. Severe Combined Immune Deficiency. 2000. Bahrainwala AH, Vish M, Moore E, and Secord EA. Intact skin reactivity to codeine in HIV infected children with and without immune reconstitution. ACAAI Nov 2000 and Annals of Allergy Asthma and Immunology, 86:131, 2000. Bahrainwala AH, Vish MG, Vinuya RZ, Pepper L, Starrs DH. Does telemarketing improve follow up office visit compliance in asthmatic patients? Annals Allergy 84(1):162, 2000. Pansare M., Genyea C., Kaplan J., and Secord EA. Oral tolerance induction to anti-factor VIII antibodies in neonatal BALB/C mice. JACI, 105(1):S165(503), 2000. Pansare M and Bahrainwala AH. Desensitization to allopurinol in a renal transplant patient with severe tophaceous gout. Annals of Allergy, Asthma & Immunology 84(1):152, 2000. Secord EA, and Kaplan J. Oral tolerance induction to the development of human factor VIII antibodies in neonatal BALB/C mice via breastmilk. Clinic Days, Children’s Hospital of Michigan. June, 2000. Valentini RP and Moore EC. Renal disease and microalbuminuria in HIV(+) children—A single center experience. Poster presentation at the ASN 33rd Annual Meeting, Toronto, ON, October 10-16. J Amer Society of Nephrology Vol. 11; A0543:100A, 2000. Younes J, Long PM, Secord EA. Common variable immune deficiency associated with pan-hypopituitarism in a nine year old girl. Amer Acad of Allergy & Immunol. March 2000. JACI, 105(1):S30(88), 2000. Younes J, Secord EA, And Bahrainwala AH. Trial of intravenous immunoglobulin in a child with autoimmune enteropathy associated with low IgG. ACAAI Nov 2000 and Annals of Allergy Asthma and Immunology, 86:129, 2000.
Division of Critical Care Medicine Heidemann SM, Lomo L, Ofenstein JP, Sarnaik AP: The effect of heat on cytokine production in rat endotoxemia. Crit Care Med (In Press) Gharpure V, Meert KL, Sarnaik AP, Metheny NA: Indicators of post-pyloric tube placement in children. Crit Care Med (In Press) Sarnaik AP: A student, a nun, and a professor. Pediatr Crit Care Med 1:176-178, 2000 Heidemann SM, Lomo L, Ofenstein JO, Sarnaik AP The Effect of Heat on Cytokine Production in Rat Endotoxemia. Crit. Care. Med. 28:1465-1468, 2000 Ofenstein JO, Heidemann SM, Juett-Wilstermann A, Sarnaik AP Expression of Stress Proteins HSP 72 and HSP 32 in Response to Endotoxemia. Ann Clin Lab Sci 30:1-6, 2000 Deshpande GG, Heidemann SM, Sarnaik AP Heat Stress is Associated with Decreased Lactic Acidemia in Rat Sepsis. Crit Care Med 4:45-49,2000 Arnold J, Anas NG, Luckett P, Cheifetz I, Reyes G, Newth C, Kocis K, Heidemann SM, Hansen JH, Brogan TV, Bohn D. High Frequency Oscillatory Ventilation in Pediatric Respiratory Failure: AMulticenter Experience. Crit Care Med 28:3913-3919, 2000 Meert, KL Thurston CS, Sarnaik, AP: Parental Decision Making and Experience with Death in the Pediatric Intensive Care Unit. Pediatric Critical Care Medicine 1: 179-185, 2000. Lieh-Lai M: Syndrome of inappropriate antidiuretic hormone secretion after spinal surgery in children. Crit Care Med, 28:3126-3129, 2000
Books, Chapters and Reviews Lieh-Lai M, Editor, Pocket Pediatrics, Lippincott, Williams and Wilkins, Philadelphia, December 2000 Lieh-Lai M, Editor, Pediatric Acute Care Handbook, 2nd edition, Lippincott, Williams & Wilkins, Philadelphia (in press)
Abstracts Meert KL, Thurston CS, Sarnaik AP: Prental decisions regarding limitations of care and withdrawal of life support in critically ill children. Crit Care Med 27:A83,2000. Presented at the Society of Critical Care Medicine, Orlando, FL, 2/2000 Meert, K.L., Thurston C.S., Sarnaik A.P.: Parental Decisions Regarding Limitation of Care and Withdrawal of Life Support in Critically Ill Children. Crit Care Med 27:A83, 2000. Presented at the Society of Critical Care Medicine, Orlando, FL, 2/00 Meert, K.L., Thurston C.S., Sarnaik A.P.: Parental Experience with Death in the Pediatric Intensive Care Unit. Crit Care Med 27:A83, 2000. Presented at the Society of Critical Care Medicine, Orlando, FL, 2/00 Gharpure V., Heidemann S.M., Glibetic M. Heat Stress Inhibits Inducible Nitric Oxide Synthase in Rat Endotoxemia. Ped. Res. 47:56A, 2000, Society for Pediatric Research meeting, Boston, MA 5/00 Meert KL, Thurston CS, Sarnaik AP: Parenteral experience with death in Pediatric Intensive Care Unit. Ped Res 47:59A, 2000. Presented at the Society of Pediatric Research, Boston, MA, 5/2000 Garekar S., Heidemann S.M. A Temperature Dependent Increase in TNF Production is Present in Lipopolysaccharide Exposed Macrophages. Ped. Res. 47:56A, 2000, Society for Pediatric Research meeting, Boston, MA 5/00 Heidemann S.M., Glibetic M. Heat Stress Induces MIP-2 Production in the Lungs of Endotoxemic Rats. Ped. Res. 47:57 A, 2000, Society for Pediatric Research meeting, Boston, MA 5/00 Meert, K.L., Thurston C.S., Sarnaik A.P.: Parental Experience with Death in the Pediatric Intensive Care Unit. Ped Res. 47:59A, 2000. Presented at the Society for Pediatric Research, Boston, A, 5/00 Kannan, S, Meert, K.L., Mooney, J., Warrier I.: Bleeding and Coagulation Changes in Children and Adolescents Undergoing Spinal Fusion Surgery: A Pilot Study. Presented at the American Society of Pediatric Hematology/Oncology, Minneapolis, MN, 9/00
Division of
Emergency Medicine Rosenberg, NM Is it or isn’t it, Pediatric Emergency Care, 2000 Apr; 16(2):130-3 Rosenberg, NM Antibiotic Conundrum –Pediatric Emergency Care, 2000 Feb; 16(1): 61-4, Division of
Gastroenterology and Nutrition Madani S, Rabah R, Tolia V: Diagnosis of Helicobacter pylori infection from antral biopsies in pediatric patients: Is Urease test that reliable? Dis Dis Sci 45:1233-1237,2000. Hurwitz M, Vargas J, Ament ME, Tolia V, Molleston J et al. Evaluation of the Use of Botulinum Toxin in Children with Achalasia. J Pediatr Gastroenterol Nutr. 30:509-514,2000. Tolia V, Brown W, El-Baba M, Lin CH. Antimicrobial susceptibility of H.pylori from children in Michigan. Pediatr Infect Dis J 19:1167-1171,2000. Kaddu R, Bawle E, Tolia V, Tunnessen W. Banayan Rubalcava-Riley Syndrome Arch Dis Pediatr Adolescent Med. 155;87-88,2001. Levy J, Hayes C, Kern J, Harris, Flores A, Hyams J, Murray R, Tolia V. Does Cisapride Influence Cardiac Rhythm? Results of a US Multicenter. Double-Blind. Placebo Controlled Pediatric Study. J Pediatr Gastroenterol Nutr (in press). Lyons H, Tolia V, Lin CH: Induction of gastric ornithine decarboxylase in early weaning rate. Digestion (in press). Kaddu R, Bhattacharya D, Metriyakool K, Thomas R, Tolia V. Propofol for endoscopic procedures in children. Gastrointest Endosc (in press). Dahshan A, Poulik J, Tolia V. Pernicious anemia in juvenile diabetic. Arch Dis Pediatr Adolescent Med (in press). Kaddu R, Tolia V. A case of gastrojejunostomy bulk obstruction mimicking ventriculoperitoneal shunt malfunction. J Ped Gastroenterol and Nutr (in press). Hussain S, Bloom D, Tolia V. A case of Caroli’s disease diagnosed by MRCP. Clinical Imaging (in press). Tolia V. Indications for proton pump inhibitors in paediatrics. In press with Paediatrics Today. Sukerek H, Tolia V. Indications for prokinetics in the management of paediatric gastroesophageal reflux. In press with Paediatrics Today. Gilger M, Chong S, Elitsur Y, Elkayam O, Gold B, Rosenberg A, Jibaly R, Johnson A, Rabinowitz S, Rosenthal P, Tolia V, Marchildon P, Peacock J. The use of a salivary immunoglobulin G ELISA for the detection of Helicobacter pylori in children. Helicobacter 2001 (in press).
Books, Chapters and Reviews El-Baba M, Tolia V. Pediatric Gastrointestinal Disease, Eds. Licouras and Altshuler. In Am J Gastroenterology 95(3):854,2000. Tolia V, Peters JM, Gilger M. Sedation in pediatric GI endoscopic procedures. J Pediatr Gastroenterol Nutr. 30;477-486,2000.
Abstracts Lin CH, Tolia V, Vijesurier RM. Regulation of intestinal orinthine decarborboxylase (ODC) Expression during postnatal development by ODC antizyme in rats. Gastroenterology 118,4,A:292,2000. Mulberg A, Tolia V. et al. Dietary intake of subjects with alagille syndrome compared to normal subjects in the United States population. Gastroenterology 118,4:A68,2000. El-Baba M, Peters JM, Lin CH, Sukerek HS, Tolia V. Value of serologic markers in children with inflammatory bowel disease (IBD). Gastrointest Endosc. 51,4:(2),AB259,2000. Gupta SK, Tolia V, Heyman MK et al. Adolescent patients with gastroesophageal reflux disease. Result from a randomized trial of Lansoprazole. Gastroenterology 118,9:A1242,2000. Dahshan AH, Patel H, Delaney J, Thomas R, Tolia V. Gastroesophageal reflux disease and Dental erosion in children. Gastrointest Endosc. 51,4:(2),AB113,2000. El-Baba M, Peters JM, Lin CH, Sukerek HS, Tolia V. Value of serologic markers in children with Inflammatory bowel disease (IBD). J Pediatr Gastroenterol Nutr 31,2:A59,2000. Tolia V, Brown W, El-Baba M, Peters J, Lin CH. Helicobacter pylori culture and antimicrobial sensitivity from children in Michigan. J Pediatr Gastroenterol Nutr 31,2:A812,2000. Lin CH, Tolia V, Vijesurier RM. Glucocorticoids are important in inducing intestinal ornithine Decarboxylase and its inhibitors, ODC antizyme, during postnatal development in rats. J Pediatr Gastroenterol Nutr 31,2:A394,2000. Gupta S, Tolia V, Heyman M, Kane R, Chiu Y, Pan W, Huang B, Pilmer B, Hassall E. Adolescent Patients with Gastroenterology Reflux Disease: Results From a Randomized Trial of Lansoprazole. J Pediatr Gasteroenterol Nutr 31,2:A377,2000. Gremse D, Tolia V, Pan W, Kane R, Karol M, Chiu Y, Pilmer B, Book L. Pharmacokinetic/Pharmacodynamics of Lansoprazole in Pediatric Patients with Symptomatic Gastroesophageal Reflux Disease. J Pediatr Gastroenterol Nutr 31,2:A144,2000. Levy J, Hayes C, Kern J, Harris, Flores A, Hyams J, Murray R, Tolia V. Does Cisapride Influence Cardiac Rhythm? Results of a US Multicenter. Double-Blind. Placebo Controlled Pediatric Study.J Pediatr Gastroenterol Nutr 31,2:A388, 2000. Tolia V, Ferry G, Gumasekaran T, Huang B, Keith R, Book L. Efficacy of lansoprazole in the Treatment of GERD in children. Am J Gastroenterol 95,(9):122,2000. Tolia V, Fitzgerald J, Hassall E, Huang B, Pilmer B, Kane R. Safety of lansoprazole in the Treatment of GERD in children. Am J Gastroenterol 95,(9):123,2000. Tolia V. Role of 6-MP metabolities in children and adolescents with chronic active hepatitis. Gastrointest Endosc. 53,2001. (in press). Afzal N, Wuerth A, Tolia V, Kemper K, Bousvaros A, Heuschkel R. The use of alternative medicines in children and young adults with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 200. (in press).
Division of General
Pediatrics Asano E, Chugani DC, Muzik O, Shen C, Juhász C, Janisse J, Ager J, Canady A, Shah JR, Shah AK, Watson CE, Chugani HT: (2000) Multimodality imaging for improved detection of epileptogenic lesions tuberous sclerosis complex. Neurology 54:1976-1984. Pfund Z, Chugani DC, Juhasz C, Muzik O, Chugani HT, Wilds IB, Seraji-Bozorgzad N, Moore GJ: (2000) Evidence for coupling between glucose metabolism and glutamate cycling using FDG PET and 1H MRS in epilepsy patients. Journal of Cerebral Blood Flow and Metabolism 20: 871-878. Juhasz C, Chugani DC, Muzik O, Watson C, Shah J, Shah A, Chugani HT: (2000) Is epileptogenic cortex truly hypometabolic on interictal positron emission tomography? Annals of Neurology 48: 88-96. Juhasz C, Chugani DC, Muzik O, Watson CE, Shah J, Shah A, Chugani HT: (2000) Electroclinical correlates of PET abnormalities in patients with epilepsy and brain lesion. Neurology 55: 825-835. Muzik O, Chugani DC, Juhasz C, Shen C, Chugani HT: (2000) Statistical parametric mapping: Assessment of application in children. NeuroImage 12: 538-549. Pfund Z, Chugani HT, Juhasz C, Muzik O, Behen ME, Chugani DC, Nigro MA, Trock GL, Squires LA: (2000) Lissencephaly: Fetal pattern of glucose metabolsm on positron emission tomography? Neurology 55:1683-1688. Chugani DC, Muzik O, Juhasz C, Janisse JJ, Ager J, Chugani HT: Ontogeny of human GABAA receptors measured with positron emission tomography. Annals of Neurology (in press). Asano E, Kuivaniemi H, Huq M, Tromp G, Behen M, Rothermel R, Herron J, Chugani DC: A study on novel polymorphisms in the upstream region of vasoactive intestinal polypeptide receptor type 2 gene in autism. J. Child Neurology (in press). Hammami M, Koo M, Koo W, Thomas R, Rakhman D. Regional bone mass measurement from whole body dual energy x-ray absorptiometry scan. Clinical Densitometry. In Press, October, 2000. Rabah R, Sakr W, Thomas R, Lancaster W, Gregoire L. Human Papillomavirus Types, Proliferation Activity and p53: Potential Markers of Aggressive Papillomatosis. Archives of Pathology and Laboratory Medicine. May 2000, Vol. 124: 721-724. Shashiditar H, Thomas R, Tolia V. A Prospective Trial of Lanoprazoli Triple Therapy for Pediatric Helicobacter Pylori Infection. Journal of Pediatric Gastroenterology and Nutrition, March 2000, Vol.30: 276-282. Raju N, Bharadwaj R, Thomas R, Konduri, G. Ibuprofen use to reduce the incidence and severity of bronchopulmonary dysplasis: a pilot study. Journal of Perinatology, January February 2000; 20(1):13-6. Giblin, P.T., Immunization activities in Michigan: An investigation and refinement of the community health improvement process. Leadership in Public Health, in press. Marshall, S., Backos, A., Giblin, P.T., Simpson, P. Adolescent girls’ perceptions and experiences with the reality female condom. Journal of Adolescent Health, in press. Chugani DC, Chugani HT: PET: Mapping of serotonin synthesis. In Functional imaging in the epilepsies, eds. Henry TR, Duncan JS, Berkovic SF. Adv Neurol. 2000; 83:165-71. Chugani HT, Chugani DC: Abnormal development and catastrophic epilepsies: The clinical picture and relation to neuroimaging. In: Brain Plasticity and Epilepsy. International Review of Neurobiol, 2001; 45: 141-157. Barami K, Hutchins KD and WD Lyman. Neurotransmitter distribution in the second trimester fetal human corpus striatum. Neurological Research (2000) in press. Barami K, Grever WE, Diaz FG and WD Lyman. An efficient method for the culturing and generation of neurons and astrocytes from second trimester human central nervous system tissue. Neurological Research (2000) in press. Barami K, Zhao J, Diaz FG and WD Lyman. Comparison of neural precursor cell fate in second trimester human brain and spinal cord. Neurological Research (2000) in press. Rabah R, Sakr W, Thomas R, Lancaster W, Gregoire L. Human Papillomavirus Types, Proliferation Activity and p53: Potential Markers of Aggressive Papillomatosis. Archives of Pathology and Laboratory Medicine. May 2000, Vol. 124: 721-724. Rabah R, Lancaster WD, Thomas R, Gregoire L. Human Papillomavirus-11 associated Recurrent Respiratory Papillomatosis is More Aggressive Than Human Papillomavirus-6 Associated Disease. Pediatr Dev Pathol (in press)
Books, Chapters and Reviews Shah JR, Chugani DC, Chugani HT: Diagnostic positron emission tomography. (Oxbury J, Polkey C, Duchowny M, eds.) In: Intractable Focal Epilepsy: Medical and Surgical Treatment. W.B. Saunders Co., London 2000; 311-321. Muzik O, Chugani DC, Shen C, Juhasz C, von Stockhausen HM, Chugani HT: (2001) Assessment of the performance of FDG and FMZ PET imaging against the gold standard of invasive EEG monitoring for the detection of extratemporal lobe epileptic foci in children. In Molecular and Pharmacological Brain Imaging with Positron Emission Tomography, eds. Gjedde A, Hansen SB, Knudsen GM, Paulson OB. Academic Press, San Diego, 381-387. Chugani DC, Muzik O: (2000) a[C-11]Methyl-L-tryptophan PET maps brain serotonin synthesis and kynurenine pathway metabolism. J Cerebral Blood Flow & Metabolism 20: 2-9. Juhasz C, Chugani DC, Muzik O, Watson C, Shah J, Shah A, Chugani HT: (2000) The relationship between EEG and PET abnormalities in clinical epilepsy. J Clin Neurophysiol 17: 29-42. Chugani DC, Chugani HT: New directions in PET neuroimaging for neocortical epilepsy. In Neocortical Epilepsies, eds. Williamson PD, Siegel AM, Roberts DW, Thadani VM, Gazzaniga MS. Adv Neurol 2000; 84: 447-456.
Abstracts Juhasz C, Muzik O, Chugani DC, Rothermel RD, Behen ME, Chugani HT: Ontogeny of human GABAA receptors studied by positron emission tomography. Child Neurology Society 29th Annual Meeting, San Diego (accepted as platform presentation) 2000: 48: 517. Lee JS, Asano E, Juhasz C, Pfund Z, Behen M, Muzik O, Chugani DC, Chugani HT: Sturge-Weber syndrome with unihemisphereic involvement: Correlation between clinical characteristics and FDG PET findings. Child Neurology Society 29th Annual Meeting, Annals Neurol. 2000; 48: 531. Chugani DC, Behen ME, Asano E, Lee J, Rothermel R, Muzik O, Chugani HT: Behavioral subtypes of autistic children show differences in regional brain serotonin synthesis. Soc. Neurosci. Abstracts, 2000, accepted for platform presentation. Asano E, Chugani DC, Behen M, Rothermel R, Muzik O, Chugani HT: Autism in tuberous sclerosis complex: Evidence for cortical and subcortical mechanisms. Soc. Neurosci. Abstracts, 2000 (accepted for poster presentation). Pfund Z, Chugani DC, Juhasz C, Muzik O, Chugani HT, Wilds IB, Seraji-Bozorgzad N, Moore GJ: (2000) Evidence for coupling between glucose metabolism and glutamate cycling using FDG PET and 1H MRS in epilepsy patients. Epilepsia 41(Suppl. 7): 67. Lee JS, Asano E, Juhasz C, Pfund Z, Muzik O, Chugani DC, Chugani HT: Sturge-Wever Syndrome with unilateral leptomeningeal angioma: Degree and extent of glucose hypometabolism are related to epileptiform pattern. Epilepsia 41 (Suppl. 7): 188. Asano E, Chugani DC, Juhasz C, Muzik O, Philip S, Shah J, Shah A, Watson C, Canady A, Chugani HT: (2000) Epileptogenic zones in tuberous sclerosis complex: Subdural EEG versus MRI and FDG PET. Epilepsia 41(Suppl. 7): 128. Juhasz C, Muzik O, Chugani DC, Chugani HT: (2000) GABAA receptors in epileptic children: Age-related changes and effect of antiepileptic drugs. Epilepsia 41 (Suppl. 7): 83. Asano E, Kuivaniemi SH, Huq M, Tromp G, Behen M, Rothermel R, Herron, Chugani DC: Novel polymorphisms in the uptream region of VIPR2 gene have a possible role in gastrointestinal problems and stereotypical behaviors in autism. 50th Annual Meeting of the American Society of Human Genetics, Philadelphia, PA October 3-7, 2000 (accepted for poster presentation). Chugani DC, Behen ME, Asano E, Lee J, Rothermel R, Muzik O, Chugani HT: Behavioral subtypes of autistic children show differences in regional brain serotonin synthesis. Soc. Neurosci. Abstracts, 2000, accepted for platform presentation. Hamre MR, Severson RK, Metzger K, Chuba P, Thomas R, Ravindranath Y. Ethnic differences in the incidence of childhood cancer in the United States. Med Pediatr Oncol 35: 204, 2000. Hamre MR, Chuba P, Severson RK, Metzger K, Roarty J, Thomas R, Ravindranath Y. Increased incidence of unilateral and bilateral retinobalstoma among individuals of Hawaiian ethnicity. Med Pediatr Oncol 35: 282, 2000. Angelilli M, Thomas R. An Improved Statistical Method to Evaluate the Reliability of Inter-Rater Clinical Assessments. Pediatric Research APS-SPR, May 2000, Vol. 46. Zhao J, Hao, H.N. Barami K, Thomas R, Lyman W.D. An Efficient Method for the Cryopreservation of Fetal Human Liver Hematopoietic Progenitor Cells. Pediatric Research APS SPR, May 2000, Vol. 46. Grever WE, Acsadi G, Anguelov R, Jani A and WD Lyman. Gene therapy for spinal cord diseases: an in vitro model using human tissue. (2000) Presented at the annual meeting of the Pediatric Academic Societies, Boston, MA. Zhao J, Hao H-N, Barami K and WD Lyman. An efficient method for the cryopreservation of fetal human liver hematopoietic progenitor cells. (2000) Presented at the annual meeting of the Pediatric Academic Societies, Boston, MA. Barami K, Grever WE and WD Lyman. Comparison of neural progenitor fate in second trimester fetal human brain and spinal cord. (2000) Presented at the annual meeting of the Pediatric Academic Societies, Boston, MA. Hao H-N, Zhao J, Lotoczky GA, Grever WE and WD Lyman. HIV tat protein up-regulates interleukin-1 b converting enzyme expression in fetal human microglia and astrocytes. (2000) Presented at the annual meeting of the Pediatric Academic Societies, Boston, MA. Hao H-N and WD Lyman. Human neutrophilic defensin HNP-1 is cytotoxic to neuroepithelial and endothelial cells, but human epitelial produced defensin hBD2 is not. (2000) Presented at the annual meeting of the Pediatric Academic Societies, Boston, MA. Hao H-N, Zhao J, Thomas RA and WD Lyman. HIV-1 virus passaged through microglia changes its chemokine receptor specificity. (2000) Presented at the annual meeting of the Pediatric Academic Societies, Boston, MA. Hao H-N, Zhao J, Lotoczky GA, Grever WE, Abdel-Haq N and WD Lyman. Induction of human b-defensin expression in neural cells: the potential role of the blood brain barrier (BBB) against bacterial infection. (2000) Presented at the annual meeting of the Pediatric Academic Societies, Boston, MA. Konduri KS, Nandedkar S, Artwall J, Bunte R and WD Lyman. A novel approach for the development of a chronic experimental asthma model in mice. (2000) Presented at the annual meeting of the Pediatric Academic Societies, Boston, MA. Johnson A, Abella EM, Kukuruga DL, Whitten-Shurney W, Baynes RD, WD Lyman, Whitten CF and MI Evans. In-utero transplantation of paternal CD34 enriched T-cell depleted hematopoietic stem cells for treatment of sickle cell anemia. (2000) Presented at the annual meeting of the Society for Gynecologic Investigation. Thomas RA, Bergh S and WD Lyman. A novel stem cell derived gene therapy for HIV/AIDS. (2000) Presented at the annual meeting of the Pediatric Academic Societies, Boston, MA. Hill, D.D., Joseph, C.L.M., Jacobsen, G., Njoh, W.S., Giblin, P.T. Predictors of vaccination coverage for the 4:3:1:3:3 series in an urban population. Paper presented at the 34th National Immunization Conference, Washington, DC, July, 2000. Njoh, W.S., Kallenbach, L., Giblin, P.T., Hill, D.D., Weir, S. Establishing and maintaining continuity of care through use of continuity coordinators. Paper presented at the 34th National Immunization Conference, Washington, DC, July, 2000. Division of Genetics Teshima I, Bawle EV, Weksberg R, Shuman C, Van Dyke DL, Schwartz S: Analphoid 3qter markers. Am J Med Genet 94:113-9,2000 Stanitski DF, Nadjarian R, Stanitski CL, Bawle E, Tsipouras P: Orthopedic manifestations of Ehlers Danlos syndrome. Clin Orthop 376:213-21, 2000
Abstracts Wiktor A, Feldman GL, Bawle E, Czarnecki P, Conard J, Van Dyke DL:Deletion of 2q37 and duplication of 10q24.Am J Hum Genet 67:162,2000
Division of Hematology/Oncology Baynes RD, Dansey RD, Klein JK, Karanes C, Abella E, Cassells L, Wei WZ, Galy A, Wood G, Peters WP: High dose chemotherapy and peripheral blood progenitor cell transplantation in patients with breast cancer. Invited review. Cancer Invest 18(5):440-55, 2000. Baynes RD, Hamm C, Dansey R, Klein J, Cassells L, Karanes C, Abella E, Peters WP: Bone marrow and peripheral blood hematopoietic stem cell transplantation: focus on autografting. Clin Chem 46(8, pt. 2):1239-51, 2000. Bhambhani K : Lead poisoning in children: A major public health concern. Synopsis 2(2):5-14, 2000. Bhambhani K: Lead poisoning in children: a major public health concern. In: (Gupte S and Gupte SB, Eds.), Recent Advances in Pediatrics 11:346-362, 2001. Jaypee Brothers Medical Publishers (P) Ltd., New Delhi, India. Chang M, Raimondi SC, Ravindranath Y, Carroll AJ, Camitta B, Gresik MV, Steuber CP, Weinstein H: Prognostic factors in children and adolescents with acute myeloid leukemia (excluding children with Down Syndrome and acute promyelocytic leukemia): univariate and recursive partitioning analysis of patient treated on Pediatric Oncology Group (POG) Study 8821. Leukemia 14(7) [July]:1201-1207, 2000. Coyne M, Lusher JM: Hemophilia emergency care. Emerg Med 32:69-77,2000. Evans WE, Hon Y-Y, Bpomgaars L, Coutre S, Holdsworth M, Janco R, Kalwinsky D, Keller F, Khatib Z, Margolin J, Murray J, Quinn J, Ravindranath Y, Ritchey K, Roberts W, Rogers ZR, Schiff D, Steuber C, Tucci F, Kornegay N, Krynetski EY, Relling MV: Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. J Clin Oncol (in press). Ewenstein BM, Hoots WK, Lusher JM, DiMichele D, White GC, Adelma B, Nadeau K: Inhibition of CD40 Ligand (CD154) in the treatment of Factor V inhibitors. Haematologica 85 (supl. 10):35-39, 2000. Ge Y, Konrad MA, Matherly LH, Taub JW: Transcriptional regulation of the human cystationine-b-synthase -1B basal promoter: synergistic transactivation by transcription factors NF-Y and Sp1 /SP3. Biochem J (in press). Hamre M, Williams JA, Chuba PT, Bhambhani K, Ravindranath Y, Severson RK: Early deaths in childhood cancer. Med Ped Oncol 34:343-347, 2000. Jadhav M, Langenburg S, Fontanesi J, Slovis TL, Taub JW: Hepatoblastoma with spinal metastases. J Pediatr Hematol Oncol 22(6):524-526,2000. Jadhav M, Warrier I: Anaphylaxis in patients with hemophilia. Semin Thrombos Hemostas 26(2):205-208, 2000. Johnson RM, Goyette G, Ravindranath Y, Ho S: Red cells from glutathione perioxidase-1-deficient mice have nearly normal defenses againast exogenous peroxides. Blood 96(5):1985-88, 2000. Klein JL, Rey PM, Dansey RD, Karanes C, Du W, Abella E, Cassells L, Hamm C, Peters WP, Baynes RD: Cardiac sequelae of doxorubicin and paclitaxel as induction chemotherapy prior to high-dose chemotherapy and peripheral blood progenitor cell transplantation in women with high-risk primary for metastatic breast cancer. Bone Marrow Transpl 25:1047-1052, 2000. Kulkarni R, and Lusher JM: Perinatal issues and management in haemophilia. Brit J Haematol 112(2):264-274,2001. Laver JH, Barredo JC, Amylon M, Schwenn M, Kurtzberg J, Camitta BM, Pullen J, Link MP, Borowitz M, Ravindranath Y, Murphy SB, Shuster J: Effects of cranial radiation in children with high risk T-cell acute lymphoblastic leukemia: a Pediatric Oncology Group report. Leukemia 14:47-51, 2000. Lusher JM: Acute hemarthroses - the benefits of early vs. late treatment with recombinant Factor VIIa. Blood Coag Fibrinolysis 11(suppl. 1):S45-S49, 2000. Lusher JM: Factor VIII inhibitors with recombinant products: prospective clinical trials. Haematologica 85 (supl. 10):2-5, 2000. Lusher JM: First and second generation recombinant clotting factor concentrates - results of controlled clinical trials. Semin Thromb & Haemost (in press). Lusher JM: Inhibitor antibodies to Factor VIII and Factor IX: management. Semin Thrombos Haemost 26(2): 179-188, 2000. Lusher JM: Recombinant clotting factors: a review of the current clinical status. BioDrugs 13(4):289-298,2000. Lusher JM: Inhibitors in young boys with haemophilia A and B. Bailliere's Clin Haematol 13(3): 457-468, 2000. Madhavi J, Cushing B, Ozdemir O, Mohamed A, Ravindranath Y, Savasan, S: Clonal trisomy 11 in a child with acute leukemia: G banding vs FISH. Med Ped Oncol, (in press). Ozgen U, Savasan S, Buck S, Ravindranath Y Comparison of DiOC6(3) uptake and Annexin V labeling for quantification of apoptosis in leukemia cells and non-malignant T-lymphocytes from children. Commun Clin Cytometry 42:74-78, 2000. Ozgen U, Savasan S, Stout M, Buck S, Ravindranath Y: Further elucidation of mechanisms of resistance to vincristine in myeloid cells: role of hypochlorous acid in degradation of vincristine by myeloperoxidase. Leukemia 14:47-51, 2000. Perlman EJ, Hu J, Ho D, Cushing B, Lauer S, Castleberry : Genetic analysis of childhood endodermal sinus tumors by comparative genomic hydribization. J Ped Hem/Onc 22(2):100-105, 2000. Pollock BH, DeBaun MR, Camitta BM, Shuster JJ, Ravindranath Y, Pullen J, Land VJ, Mahoney DH Jr., Lauer SJ, Murphy SB: Racial differences in the survival of childhood B-precursor acute lymphoblastic leukemia: a Pediatric Oncology Group study. J Clin Oncol 18(4):813-823, 2000. Ragni MV, Lusher JM, Koerper M, Manco-Johnson M, Krause DS: Safety and immunogenicity of subcutaneous hepatitis A vaccine in children with hemophilia. Haemophilia 6(2):98-103, 2000. Sakhalkar VS, Sarnaik SA, Asmar BI, Conner-Warren R, Shurney W, Abdel-Haq NM: Prevalence of penicillin-nonsusceptible Streptococcus pneumoniae in nasopharyngeal cultures from patients with sickle cell disease. South Med J (in press). Savasan S, Taub JW, Buck S, Botterill M, Furlan M, Ravindranath Y: Congenital microangiopathic hemolytic anaemia and thrombocytopenia with unusually large von Willebrand Factor multimers and normal activity of von Willebrand Factor-cleaving protease. J Ped Hematol Oncol (in press). Savasan S, Taub JW: Down syndrome and leukemia: what have we learned? Pediatr Pathol Mol Med 19:269-281,2000. Shah SJ, Taub JW, Witt TL, Pollock BH, Bing B-C, Moore DS, Amylon M, Pullen J, Ravindranath Y, Matherly LH: Relationship of p15 and p16 gene alternations to elevated dihydrofolate reductase in childhood acute lymphoblastic leukemia. Brit J Haematol (in press). Taub JW, Huang X, Ge Y, Dutcher JA, Stout ML, Mohamad RM, Ravindranath Y, Matherly LH: Cystathionine-b-synthase cDNA transfection alters the sensitivity and metabolism of cytosine arabinoside in CCRF-CEM leukemia cells in vitro and in vivo: a model of Down Syndrome in leukemia. Cancer Research 60:6421-6426, 2000. Taub JW. The relationship of Chromosome 21 and acute leukemia in Down Syndrome. J Pediatr Hematol-Oncol (in press). Unuvar A, Warrier I, Lusher JM: Immune tolerance induction in the treatment of paediatric haemophilia A patients with factor VIII inhibitors. Haemophilia 6:150-157, 2000. Warrier I: ITI in hemophilia B: possibilities and problems. International Monitor of Hemophilia 8(2):3-6, 2000. White GC, Rosendaal F, Aledort LM, Lusher JM, Rothschild C, Ingerslev J: Definitions in haemophilia. Recommendations of the Scientific and Standardization Committee on Factor VIII and Factor IX of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. (in press). Chou S-R, Brownell A, Ko M, Kaplan J: Interferon gamma receptor polymorphisms determine strain differences in accessibility of activated lymphocyte NK-triggering antigens to recognition by self-reactive NK cells. Cellular Immunology 200:88-97,2000. Kaplan J, Genyea C, Second E: Potential for prevention of inhibitor formation by immune tolerance. Seminars Thrombosis Hemostasis 26:173-177, 2000. Nicholson RH, Pantano S, Eliason JF, Kaplan J, Ko MSH: Phemx, a novel mouse gene expressed during hematopoiesis, maps to the imprinted cluster on distal chromosome 7. Genomics 68:13-21, 2000.
Books, Chapters and Reviews
Abstracts, Letters to the Editor and Articles in Non-Refereed Journals
Czarnecki PM, Brooks DG, Rao R, Taub JW, Stambolian DE, Bawle EV: Three generation family with hereditary hyperferritinemia-cataract syndrome carrying a missense mutation in the L-ferritin gene. Presented at the Annual Meeting of the American Society of Human Genetics, Philadelphia, PA, Oct. 3-7, 2000. Am J Hum Genet 67(suppl. 2):389, abstract # 2183, 2000. Dansey RD, Karanes C, Klein JL, Abella E, Cassells LJ, Hamm C, Baynes RD, King R, Peters WP: Updated results of autologous stem cell transplantation for relapsed/refractory Hodgkin's Disease using cyclophosphamide platinum and BCNU (CPB/Stamp I). Proceed of ASCO 19:64a, abstract # 247, 2000. Presented at the 2000 ASCO meeting, May 19-23, 2000, New Orleans, LA. Hamm CM, Klein JL, Dansey RD, Karanes C, Abella E, Cassells L, Peters WP, Baynes RD: CD34 selected peripheral blood progenitor cell transplantation (PBPCT) after high-dose cyclophosphamide, cisplatin, and carmustine (CPB) for breast cancer metastatic to bone or bone marrow: safety and supportive care data. Proceed of ASCO 19:57a, abstract # 220, 2000. Presented at the 2000 ASCO meeting, May 19-23, 2000, New Orleans, LA. Hamre MR, Chuba PJ, Bhambhani K, Ravindranath Y, Yap J, Severson R: Comparisons of Hodgkin’s Disease (HD) in African Americans (AA) and Caucasians (C). Presented at the 36th Annual Meeting of the American Society of Clinical Oncology (ASCO), May 20-23, 2000, New Orleans, LA. Program/Proceed of ASCO 19:19a, abstract # 67, 2000. Hamre MR, Chuba PJ, Severson RK, Metzger K, Roarty J, Thomas R, Ravindranath Y: Increased incidence of unilateral and bilateral retinoblastoma among individuals of Hawaiian ethnicity. Presented at the 32nd Annual meeting of the International Society of Paediatric Oncology (SIOP), Oct. 4-7, 2000, Amsterdam, The Netherlands. Med Ped Oncol 35(3):282, abstract # P-246, 2000. Ivascu NS, Sarnaik S, McCrae J, Whitten-Shurney W, Thomas R, Bond S: Characterization of pica prevalence among patients with Sickle Cell Disease. Ped Res (in press), 2001. Konrad M, Ge Y, Naber J, Scott JS, Matherly LH, Taub JW: Leukemic clones are frequently present in neonatal blood samples of children with acute lymphoblastic leukemia (ALL). Presented at the 92nd Annual Meeting of the American Association of Cancer Research (AACR), New Orleans, LA, March 24-28, 2001. Proceed Am Assoc Cancer Res 42:408, abstract # 2196, 2001. Lamba R, Mohamed A, Kukuruga D, Karanes C, Klein J, Dansey R, Savasan S, Du W, Baynes R, Abella E: Analysis of chimerism pattern in children after allogeneic BMT and clinical implications. Presented (poster) at the 32nd annual SIOP meeting, Oct. 5-7, 2000, Amsterdam. Med Ped Oncol 35(3):244, abstract # P-90, 2000. Lusher JM, Petrini P, Angiolillo A, Nguyen K, Nissen S, Wiken M, Rup B, Bedrosian CL, and the ReFacto Study Group: Antibody and inhibitor patients in previously untreated patients (PUPs) treated exclusively with B-domain deleted recombinant factor VIII (BDDrFVIII). Presented at the ASH meeting, Dec. 1-5, 2000. Blood 96 (11) (part 1 of 2): 266a, abstract # 1144, 2000. Lusher JM: New advances in the management of hemophilia. Presented in Education program on Coagulation Disorders, Am. Soc. of Hematology annual meeting, Dec. 1-5, 2000. (Publ. In ASH Education Booklet, 2000). Massey G, Zipursky A, Doyle J, Taub J, Ravindranath Y, Weinstein H: Presenting clinical and laboratory features of transient myeloproliferative disorders (TMD) in neonates with Down Syndrome (DS): a Pediatric Oncology Group study. Presented at the Annual Meeting of The American Society of Pediatric Hematology/Oncology, Sept. 14-16, 2000, Minneapolis, MN. J Pediatr Hematol Oncol 22:383, 2000 (abstract # 646). Massey G, Zipursky A, Doyle J, Taub J, Ravindranath Y, Weinstein H: Transient myeloproliferative disorder (TMD) in neonates with Down Syndrome (DS): early death and hepatic failure; a Pediatric Oncology Group study. Presented at the Annual meeting of The American Society of Pediatric Hematology/Oncology, Sept. 14-16, 2000, Minneapolis, MN. J Pediatr Hematol Oncol 22:383, 2000 (abstract # 647). Massey GV, Zipursky A, Doyle JJ, Taub JW, Ravindranath Y, Chang MN, Weinstein HJ: A prospective study of the natural history of transient myeloproliferative disorder (TMD) in neonates with Down Syndrome (DS): A Pediatric Oncology Group (POG) Study. Presented at the 42nd annual meeting of the American Society of Hematology (ASH), San Francisco, CA, Dec. 1-5, 2000. Blood 96(11)(part 1 of 2):744a, abstract # 3220, 2000. Nugent D, Harwood E, Lusher J, Freiberg A, Buchanan G, Sahud M, DiPaola J, Young G, Nakagawa P, and the Fibrogammin P Study Group: Pilot studies on the survival of infused Factor VIII (Fibrogammin P, Aventis) and the incidence of anti-FXIII antibodies in FXIII deficient patients. Presented at the ASH meeting, Dec. 1-5, 2000. Blood 96 (11) (part 1 of 2): 639a, abstract # 2747, 2000. Ravindranath Y, Kaspers GJL, Rots MG, van Zantwijk CH, Taub JW, Matherly LH: Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methotrexate (MTX) sensitivity in childhood B-precursor Acute Lymphoblastic Leukemia (BP-ALL). Presented at the 4th International Symposium on Drug Resistance in Leukemia and Lymphoma, March 7-10, 2001, Amsterdam, The Netherlands. Leukemia 15(3):496, abstract # P-03, 2001. Ravindranath Y, Taub JW: Down syndrome (DS) and Acute Myeloid Leukemia (AML): a model for understanding thebiochemical basis for increased drug sensitivity. Presented at the 2nd International Symposium on Childhood MDS. May 11-14, 2000, Hindsgavl Castle-Fyn, Denmark. Savasan S, Ozdemir O, Buck S, Ravindranath Y: Differential effect of dexrazoxane on the in vitro cytotoxicity of topoisomerase-II inhibitors by cell type in childhood leukmeias. Presented at the 4th International Symposium on Drug Resistance in Leukemia and Lymphoma, March 7-10, 2001, Amsterdam, The Netherlands. Leukemia 15(3):489, abstract # 0-32, 2001. Savasan S, Ozdemir O, Buck S, Ravindranath Y: The effect of dexrazoxane of in vitro cytotoxicity and apoptosis induction of topoisomerase -II inhibitors in human acute leukemia cells. Presented at the 42nd annual meeting of the American Society of Hematology (ASH), San Francisco, CA, Dec. 1-5, 2000. (Published in Blood 96(11)(part 1 of 2): 306a, abstract # 1324, 2000. Taub JW, Kaspers GJL, Rots MG, Van Zantwijk CH, Matherly LH, Ravindranath Y: Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methotrexate (MTX) sensitivity of childhood B-precursor acute lymphoblastic leukemia (BP-ALL). Presented at the 42nd annual meeting of the American Society of Hematology (ASH), San Francisco, CA, Dec. 1-5, 2000. (Published in Blood 96(11)(part 1 of 2):100a, abstract # 428, 2000. Wood GW, Dansey RD, Klein JL, Karanes C, Hamm C, Abella E, Cassells L, Skikne BS, Peters WP, Baynes RD: Combined modality high-dose chemotherapy followed by adoptive immunotherapy to eliminate minimal residual disease in metastatic breast cancer. Proceed of ASCO 19:101a, abstract # 388, 2000. Presented at the 2000 ASCO meeting, May 19-23, 2000, New Orleans, LA. Yang Li V, Nicholson RH, Kaplan J, Galy A, Li L: Hemogen-1: a novel nuclear protein expressed during the ontogeny of mouse hematopoiesis. Blood 96:136b(A), 2000.
Division of
Infectious Diseases Thisyalorn U, Khongphatthanayothin M, Sirivichayakul S, Rongkavilit C, Poolchareon W, Kunanusont C, Bien D, Phanuphak P. Thai Red Cross zidovudine donation program to prevent vertical transmission of HIV: the effect of the modified ACTG 076 regimen. AIDS 2000;14:2921-2927 Abdel-Haq NM, Asmar BI. Acute osteomyelitis in children. Synopsis 2(3):5-18, 2000. Abdel-Haq NM, Asmar BI. Antiviral therapy in children: herpes viruses. The Indian Journal of Pediatrics. In press. Rongkavilit C, Asmar BI. Antiretroviral drugs in pediatrics. The Indian Journal of Pediatrics. In press. Asmar BI, Abdel-Haq NM. Antiviral therapy in children: Respiratory infections, chronic hepatitis. The Indian Journal of Pediatrics. In press. Frateralla, D. and Abdel-Haq, N. Tetanus. e-Medicine. In press.
Books, Chapters and Reviews Asmar BI. Yersinia enterocolitica. In: Rudolph’s Pediatrics (Textbook) 21st ed. 2000. In press Rongkavilit C, Thisyalorn U, Phanuphak P. UNAIDS Best Practice Collection: Prevention of mother-to-child transmission of HIV: Thai Red Cross zidovudine donation programme. Geneva. UNAIDS, September 2000 (English and Thai versions). Rongkavilit C. Pediatric antiretroviral therapy. In: Thisyakorn U, Chotpittayasunont T, eds. Update on Pediatric Infectious Diseases IV. Bangkok: Pediatric Infectious Disease Society of Thailand, 2001. Abstracts, Letters to the
Editor and Articles in Non-Refereed Journals
Zhao J, Hao HN, Seay M, Abdel-Haq NM, and Lyman WD. Comparison of fetal human liver with cord blood hematopoietic stem cell BFU-E colony formation in response to human erythropoietin. The American Pediatric Society and The Society for Pediatric Research, May 1-4, 1999, San Francisco, CA. Pediatric Research, 45:4;154A, No. 900. Hao HN, Abdel-Haq NM, Zhao J, Lyman WD. Enhancement of HIV infection of human fetal liver and cord blood CD34+CD4-cells is mediated by upregulation of chemokine receptor expression on these cells. The American Pediatric Society and The Society for Pediatric Research, May 1-4, 1999, San Francisco, CA. Pediatric Research 45:4;162A, No. 834. Abdel-Haq NM, Hao HN, Asmar BI, and Lyman WD. Regulation of nitric oxide synthase (NOS) expression by respiratory syncytial virus (RSV) in human respiratory epithelial cells. Pediatric Research (Abstract #1504) Vol. 47 Number 4. Pediatric Academic Societies and American Academy of Pediatrics Joint Meeting May 2000. Hao HN, Zhao J, Lotoczky G, Grever WE, Abdel-Haq NM, Lyman WD. Induction of human beta defensin expression in neural cells: the potential role of blood brain barrier against bacteria infection. Pediatric Research (Abstract #2011) Vol. 47 Number 4. Pediatric Academic Societies and American Academy of Pediatrics Joint Meeting May 2000. Rongkavilit C, van Heeswijk RPG, Prisuwana P, Limpongsanurak S, Srigritsanapol A, Boonrod C, Hassink E, Mahanontharit A, Chuenyam T, Thaithumyanon P, Hoetelmans RMW, Lange JMA, Cooper DA, Phanuphak P. The safety and pharmaockinetics of nelfinavir in a dose-escalating study in HIV-1-exposed newborn infants. The 2nd International Workshop on Clinical Pharmacology of HIV Therapy, Noordwijk, The Netherlands. April 2-4, 2001 (oral and poster presentation).
Division of Pediatric Neurology Najm IM, Ying Z, Babb T, Mohamed A, Hadam J, LaPresto E, Wyllie E, Kotagal P, Bingaman W, Foldvary N, Morris H, Luders HO. Epileptogenicity correlated with increased N-Methyl-D-Aspartate Receptor Subunit NR2A/B in human focal cortical dysplasia. Epilepsia, 41(8): 971-976, 2000. Deihl B, Najm I, Lapresto E, Ruggieri P, Mohamed A, Ying Z, Lieber M, Babb T, Bingaman W, Luders HO. Temporal Lobe (TL) volumes in patients with temporal lobe epilepsy (TLE) due to hippocampal sclerosis (HS) and cortical dysplasia (CD). Epilepsia, 41(Supp 7): 62-63, 2000. Mikuni N, Babb TL, Wylie C, Ying C. NMDAR1 receptor proteins and mossy fibers in the fascia dentate during rat kainite hippocampal epileptogenesis. Experimental Neurology, 163: 271-277, 2000. Velasco AL, Wilson CL, Babb TL, Engel J Jr. Functional and anatomic correlates of two frequently observed temporal lobe seizure-onset patterns. Neural Plasticity, 7(1-2): 49-63, 2000. Chugani DC, Muzik O. Alpha[C-11]-methyl-tryptophan PET maps brain serotonin synthesis and kynurenine pathway metabolism. J Cereb Blood Flow Metab 2000; 20: 2-9 DiCarli M, Prcevski P, Singh T, Janisse J, Ager J, Muzik O, VanderHeide R. Myocardial blood flow, function and metabolism in repetitive stunning. J Nucl Med 2000; 41: 1227-34 Juhasz C, Chugani DC, Muzik O, Watson C, Shah J, Shah A, Chugani HT. Relationship between EEG and PET abnormalities in clinical epilepsy. J Clinical Neurophys 2000; 17: 29-42 Juhasz C, Chugani DC, Muzik O, Watson C, Shah J, Shah A, Chugani HT. Electroclinical correlates of flumazenil and fluorodeoxyglucose PET abnormalities in lesional epilepsy. Neurology 2000; 55: 825-34 Juhasz C, Chugani DC, Muzik O, Watson C, Shah J, Shah A, Chugani HT. Is epileptogenic cortex truly hypometabolic on interictal positron emission tomography? Annals Neurology 2000; 48: 88-96 Muench G, Nguyen N, Nekolla S, Ziegler S, Muzik O, Chakraborty P, Wieland , D, Schwaiger M. Evaluation of sympathetic nerve terminals with [C-11]epinephrine and [C-11]hydroxyephedrine and positron emission tomography. Circulation 2000; 101: 516-23. Muzik O, daSilva E, Juhasz C, Chugani DC, Shah J, Nagy F, Canady A, vonStockhausen HM, Herholz K, Gates J, Frost M, Ritter F, Watson C, Chugani HT. Comparison of intracranial EEG with flumazenil and glucose PET in children with extratemporal lobe epilepsy. Neurology 2000; 54: 171-79 Muzik O, Chugani DC, Juhasz C, Shen C, Chugani HT. Statistical parametric mapping: Assessment of application in children. NeuroImage 2000; 12: 538-49 Pfund Z, Chugani D, Juhasz C, Muzik O, Chugani H, Wilds I, Seraji-Bozorgzad N, Moore G. Evidence for coupling between glucose metabolism and glutamate cycling using FDG PET and 1H magnetic resonance spectroscopy in patients with epilepsy. JCBF 2000; 20: 871-78 Juhasz C, Chugani DC, Muzik O, Watson C, Shah J, Shah A, Chugani HT: Relationship Between EEG and positron emission tomography abnormalities in clinical epilepsy. J of Clinical Neurophysiology 17, 29-42, 2000. Pfund Z, Chugani DC, Juhasz C, Muzik O, Chugani HT, Wilds I, Seraji-Bozorgzad N, Moore GJ: Evidence for coupling between glucose metabolism and glutamate cycling using FDG PET and 1H magnetic resonance spectroscopy in patients with epilepsy. J of Cerebral Blood Flow and Metabolism 20: 871-878, 2000. Pfund Z, Chugani HT, Juhasz C, Muzik O, Behen MA, Chugani DC, Nigro MA, Trock GL, Squires LA: Lissencephaly, Fetal pattern of glucose metabolism on positron emission tomography? Neurology 55, 1683-1688, 2000. Juhasz C, Chugani DC, Muzik O, Watson C, Shah J, Shah A, Chugani HT: Electroclinical correlates of flumazenil and fluorodeoxyglucose PET abnormalities in lesional epilepsy. Neurology 55, 825-834, 2000. Juhasz C, Chugani DC, Muzik O, Watson C, Shah J, Shah A, Chugani HT: Is epileptogenic cortex truly hypometabolic on interictal positron emission tomography? Annals of Neurology 48, 88-96, 2000. Muzik O, Chugani DC, Juhasz C, Shen C, Chugani HT: Statistical parametric mapping: assessment of application in children. NeuroImage 12, 538-549, 2000. Muzik O, da Silva EA, Juhasz C, Chugani DC, Shah J, Nagy F, von Stockhausen H-M, Herholz K, Canady A, Gates J, Frost M, Ritter F, Watson C, Chugani HT: Intracranial electrophysiological significance of flumazenil and glucose PET abnormalities in children with extratemporal lobe epilepsy. Neurology 54: 171-179, 2000. Asano E, Chugani DC, Muzik O, shen C, Juhasz C, Janisse J, Ager J, Canady A, Shah JR, Shah AK, Watson CE, Chugani HT: Multimodality imaging for improved detection of epileptogenic lesions tuberous sclerosis complex. Neurology 54: 1976-1984, 2000. Chugani DC, Muzik O, Juhasz C, Janisse JJ, Ager J, Chugani HT: Ontogeny of human GABAA receptors measured with positron emission tomography. Annals of Neurology. (in press). Chugani DC, Chugani HT: New directions in PET neuroimaging for neocortical epilepsy. In Neocortical Epilepsies, eds. Williamson PD, Siegel AM, Roberts DW, Thadani VM, Gazzaniga MS. Adv Neurol 84: 447-456, 2000. Chugani DC, Chugani HT: Mapping of serotonin synthesis. In Functional Imaging in the Epilepsies, eds Henry tR, Duncan JS, Berkovic SF. Adv Neurol 83: 165-171, 2000. Stecca B, Southwood CM, Gragerov A, Kelley KA, Friedrich VL, Gow A: DM-20 cannot replace the function of PLP in CNS myelin. J Neurosci 20, 4002-4010, 2000. Southwood CM, Gow A: Insights into the mechanisms of oligodendrocyte apoptosis from hypomyelinated mice. Micros Res Tech, 2000. (in press) Huq AHMM, Nigro MA. XY sex reversal, spastic paraplegia, olivo-ponto-cerebellar atrophy, thin corpus callosum, and developmental delay: a new syndorme? Pediatric Neurology 23:357-360, 2000. Asano E, Kuivaniemi H, Huq AHMM, Tromp G, Behan M, Rothermil R, Herron J, Chugani DC: A study on novel polymorphisms in the upstream region of vasoactive intestinal peptide receptor type 2 gene in autism. J Child Neurology (in press). Selcen D, Nigro MA. High-dose intravenous immunoglobulin therapy in juvenile myasthenia gravis. Pediatric Neurology 2000;22:40-43. Glauser TA, Nigro MA, Sachdeo R, Bonet HB, Weinstein S, Abou-Khalil B, Frank M, Grinspan A, TG, Betts T, Kerrigan J, Geoffroy G, Jacobs T, Mesenbrink P, Kramer L, D’Souza J, and the Trileptal Pediatric Group. Adjunctive therapy with oxcarbazepine in children with inadequately controlled partial seizures: A multinational, multicenter, randomized, double-blind, placebo-controlled, parallel Ttrial. Neurology 2000;54:2237-2244. Selcen D, Seidman S, Nigro MA. Otocerebral anomalies associated with topical tretinoin use. Brain & Development 2000:22:218-220. Mahbubul Huq AH, Nigro MA. XY sex reversal and a nonprogressive neurologic disorder: A new syndrome? Pediatr Neurol 2000:23:357-360. Pfund Z, Chugani HT, Juhasz C, Muzik O, Behen ME, Chugani DC, Nigro MA, Trock GL, Squires LA. Lissencephaly. Fetal pattern of glucose metabolism on positron emission tomography? Neurology 2000:55:1683-1688. Selcen D, Kupsky WJ, Benjamin D, Nigro MA. Myopathy with muscle spindle excess: A new congenital neuromuscular syndrome? Muscle Nerve, in press.
Books, Chapters and Reviews
Acsadi, G: Congenital muscular dystrophy: Merosin deficient form. In: Gillman, S: (ed) Neurobase, Arbor Publ. (submitted) Muzik O, Chugani DC, Shen C, Juhasz C, vonStockhausen HM, Chugani HT. Assessment of the performance of FDG and FMZ PET imaging against the gold standard of invasive monitoring for the detection of extratemporal lobe epileptic foci in children. In: Physiological Imaging of the Brain with PET edited by Gjedde A, Hansen K. Academic Press 2000 Shah JR, Chugani DC, Chugani HT: Diagnostic positron emission tomography. In: Oxbury J, Polkey C, Duchowny M (eds): Intractable focal epilepsy. WB Saunders, pp. 311-321, 2000. Chugani HT, Chugani DC: Abnormal Development and Catastrophic Epilepsies: The clinical picture and relation to neuroimaging. In:Engel J, Schwartzkrkoin PA, Moshe Sl, Lowenstein DH (eds): Brain Plasticity and Epilepsy. Academic Press, pp. 141-155, 2000. Muzik O, Chugani DC, Juhasz C, Shen C, Chugani HT: Statistical parametric mapping: Assessment of application in children. NeuroImage 12, 538-549, 2000. Mohamed, Is. & Moorjani, Bh. Chorea in childhood. In e-medicine. St. Petersberg (in press)Khadurrah, Ah. & Moorjani, B. Benign Epilepsies of Childhood. In e-medicine. St. Petersberg (in press) Moorjani, Bh. Neonatal injury in Child Abuse. In e-medicine. St. Petersberg (in press) Southwood CM, Gow A: Functions of OSP/claudin 11-containing parallel tight junctions: Implications from the knockout mouse. In Tight Junctions. (Anderson JM, Cereijido M, eds) 2nd Ed, CRC Press, 2000 (in press) Nigro MA. Chapter 121: Seizures and status epilepticus in children. EMERGENCY MEDICINE: A Comprehensive study guide, 5th Edition. McGraw Hill, 825-838, 2000. Chugani DC, Muzik O: (2000) a[C-11]Methyl-L-tryptophan PET maps brain serotonin synthesis and kynurenine pathway metabolism. J Cerebral Blood Flow & Metabolism 20: 2-9. Juhasz C, Chugani DC, Muzik O, Watson C, Shah J, Shah A, Chugani HT: (2000) The relationship between EEG and PET abnormalities in clinical epilepsy. J Clin Neurophysiol 17: 29-42. Chugani DC, Chugani HT: New directions in PET neuroimaging for neocortical epilepsy. In Neocortical Epilepsies, eds. Williamson PD, Siegel AM, Roberts DW, Thadani VM, Gazzaniga MS. Adv Neurol 2000; 84: 447-456. Acsadi G, Anguelov R, Lewis, RA, Jani, Yang, H, Ianakova EP, Kamholz, J, Shy ME: Adenoviral-mediated GDNF gene transfer in SOD 1 transgenic mice. Neurology 2000;54 (Suppl3;A154) Acsadi G, Anguelov R, Yang, Toth G, Jani J, Lewis, RA , Shy ME: GDNF and CT-1 gene therapy prolongs the survival of SOD-1 mice. Am J Hum Genet 2000;67(4;Suppl.2)A2413 Babb TL, Wylie CJ, Bolek R. Development of NR1-NR2A/B protein subunit coassemblies and their mRNA expressions post-natally after E17 gamma irradiation-induced cortical dysplasia in rats. Epilepsia, 41(Supp 7): 26, 2000. Kunieda T, Najm IM, Kondo S, Babb T, Bingaman WE, Luders HO. Spontaneous seizure recordings in the rat model of radiation-induced cortical dysplasia. Epilepsia, 41(Supp 7): 44, 2000. Dohmen BM, Manghner T, Kuntzsch M, Bares R, Stayanoff J, Muzik O, Machulla HJ. Metabolism of F-18 FLT in patients. J Nucl Med 2000; 36P Muzik O, Chugani DC, Shen C, Juhasz C, Chugani HT. Statistical parametric mapping : Assessment of application in children. J Nucl Med 2000; 62P Shields AF, Dohmen BM, Mangner T, Lawhorn-Crews J, Machulla HJ, Muzik O, Bares R. Imaging of thoracic tumors with F-18 FLT. J Nucl Med 2000; 74P Sun H, Collins J, Mangner T, Muzik O, Shields AF. Biodistribution and metabolism of F-18 FAU.: A potential chemotherapeutic drug and PET imaging agent. J Nucl Med 2000; 264P Veerapan B, Ramappa P, Gowda S, Afonso L, Muzik O, DiCarli M. Are cardiac symptoms predictive of clinical outcomes in patients with ischemic cardiomyopathy undergoing revascularization? J Nucl Med 2000; 90P Juhasz C, Watson C, Chugani DC, Muzik O, Shah J, Shah A, Chguani HT: Epileptogenicity of ‘metabolic borderzones’ in human neocortical epilepsy. American Academy of Neurology 52nd Annual Meeting, San Diego. Neurology 54 (3) A107-A108, April 2000. Pfund Z, Chugani DC, Juhasz C, Muzik O, Chugani HT, Wilds IB, Seraji-Bozorgzad N, Moore GJ: Evidence for Coupling between Glucose Metabolisma and glutamate cycling using FDG PET and 1H MRS in epilepsy patients. Epilepsia 41:7, 67, December 2000. Watson C, Fuerst D, Poore Q, Shah J, Shah A, Hutchinson, Johnson R, Canady A, Chugani HT:Is hippocampal sclerosis (HS) a progressive disorder? Epilepsia 41:7, 68, December 2000. Asano E, Chugani DC, Juhasz C, Muzik O, Philip S, Shah J, Shah A, Watson C, Canady A, Chugani HT: Epileptogenic zones in tuberous sclerosis complex: subdural EEG versus MRI and FDG PET. Epilepsia 41:7, 128, December 2000. Lee J, Asano E, Juhasz C, Pfund Z, Muzik O, Chugani DC, Chugani HT. Sturge-weber syndrome with unilateral leptomeningeal angioma: Degree and extent of glucose hypometabolism are related to epileptiform pattern. Epilepsia 41:7, 188, December 2000. Juhasz C, Muzik O, Chugani DC, Chugani HT: GABAA Receptors in epileptic children: Age related changes and effect of antiepileptic drugs: Epilepsia 41:7, 83, December 2000. Juhasz C, Muzik O, Chugani DC, Rothermel RD, Behen ME, Chugani HT: Ontogeny of human GABAA receptors studied by positron emission tomography: Annals of Neurology 48:3, 517, September 2000. Lee JS, Asano E, Juhasz C, Pfund Z, Behen M, Muzik O, Chugani DC, Chugani DC: Sturge weber syndrome with unihemispheric involvement: Correlation between clinical characteristics and positron emission tomography flurodeoxyglucose findings. Annals of Neurology 48:3, 531, September 2000. Division of Neonatal-Perinatal
Medicine Carbone L, Tylavsky FA, Bush AJ, Koo W, Orwoll E, Cheng S. Bone density in Ehlers- Danlos Syndrome. Osteoporosis International 11:388-92, 2000 Chambers CD, Braddock S, Briggs J, Einarson A, Johnson Y, Miller R, Polifka J, Robinson L, Stepanuk K, Jones K. Post-marketing Surveillance for Human Teratogenicity: A Novel Approach. (Teratology, 2001, in press) Covington C, Nordstrom-Klee B, Delaney-Black V, Templin T, Ager J, Sokol RJ. Development of an instrument to assess problem behavior in first-grade students prenatally exposed to cocaine: Part II – validation. Substance Abuse, in press. Delaney-Black V Covington C, Templin T, Ager J, Nordstrom-Klee B, Martier S, Leddick L, Czerwinski RH, Sokol RJ: Teacher-assessed behavior of children prenatally exposed to cocaine. Pediatrics 106:782-791, 2000. Delaney-Black V, Covington C, Templin T, Kershaw T, Nordstrom-Klee B, Ager J, Clark N, Surendan A, Martier S, Sokol RJ: Expressive language development of children prenatally exposed to cocaine: Literature review and report of a prospective cohort study. Journal of Communication Disorders, 33(6): 463-480, 2000. Feng Ying CL, Brenner RA, Johnson YR, Azimi PH, Philips JB, Regan JA, Clark P, Weisman LE, Rhoads GG, Kong F, Clemens JD. The Effectiveness of Risk-Based Intrapartum Chemoprophylaxis for the Prevention of Early-Onset Neonatal Group B Streptococcal Disease. (American Journal of Obstetrics and Gynecology 2001, in press). Gervasio CT, Mantaring BS, Alankar S, Shankaran S. Early-onset neonatal group B streptococcal sepsis: Intrapartum Antibiotic prophylaxis in the clinical setting. J Perinat 2001; 21:9-14. Hammami M, Walters JC, Hockman EM, Koo WWK. Disproportionate alterations in body composition of large for gestational age neonates. The Journal of Pediatrics (In press) Hammami M, Koo MWM, Koo WWK, Thomas RT, Rakhman D. Regional bone mass measurement from whole body dual energy x-ray absorptiometry scan. Journal of Clinical Densitometry (In press) Horwitz EM, Prockop DJ, Gordon PL, Koo WWK, Fitzpatrick LA, Neel MD, McCarville MB, Orchard PJ, Pyeritz RE, Brenner MK. Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta. Blood (In press) Kazzi SNJ, Romero R, McLaughlin K, Ager J, Janisse J: Serial changes in levels of IL-6 and IL-1b among premature infants at risk for bronchopulmonary dysplasia. Pediatr Pulmonol 31(3):220-226, 2001. Kazzi SNJ, Schürch S, McLaughlin KL, Romero R, Janisse J: Surfactant phospholipids and surface activity among preterm infants with respiratory distress syndrome who develop bronchopulmonary dysplasia. Acta Paediatr 89:1218-1225, 2000. Khan N, Kazzi SNJ: Yield and costs of screening growth-retarded infants for TORCH infections. Am J Perinatol 17(3): 131-135, 2000 Koo MWM, Yang KH, Begeman P, Hammami M, Koo WWK. Prediction of bone strength in growing animals using non-invasive bone mass measurements. Calcified Tissue International (In press) Koo WWK, Hockman EM. Physiologic predictors of lumbar spine bone mass in neonates. Pediatric Research 48:485-9, 2000 Koo WWK, Walters JC, Hockman EM. Body composition in human infants at birth and postnatally. Journal of Nutrition 130:2188-94, 2000 Lemons JA, Bauer CR, Oh W, Korones SB, Papile LA, Stoll BJ, Verter J, Temprosa M, Wright LL, Ehrenkranz RA, Fanaroff AA, Stark AR, Carlo WA, Tyon JE, Donovan EF, Shankaran S, Stevenson DK. Very-low-birth-weight (VLBW) outcomes of the NICHD Neonatal Research Network, January 1995 through December 1996. Pediatrics 2001; 107:e1. Lester BM, ElSohly M, Wright LL, Smeriglio VL, Verter J, Bauer CR, Shankaran S, Bada HS, Walls HC, Huestis MA, Finnegan LP, Maza PL. The Maternal Lifestyle Study: Drug use by meconium toxicology and maternal self-report. Pediatrics 2001; 107:309-317. O’Toole ML, Johnson KC, Satterfield S, Bush AJ, Koo WWK, Klesges RC, Applegate WB. Do sweat calcium losses affect bone mass during firefighter training? Journal of Occupational and Environmental Medicine 42:1054-9, 2000 Ohls RK, Ehrenkranz RA, Wright LL, Lemons JA, Korones SB, Stoll BJ, Stark AR, Shankaran S, Donovan EF, Close NC, Das A. The effects of early erythropoietin therapy on the transfusion requirements of preterm infants below 1250 grams birthweight: a multi-center, randomized, controlled trial. Pediatrics (in press). Ostrea EM Jr., Knapp K, Tannenbaum L, Ostrea AR, Romero A, Salari V, Ager J. Estimates of illicit drug use during pregnancy by maternal interview, hair analysis, and meconium analysis. J Pediatr 2001;138:344-48 Ramirez GB, Vince Cruz C, Pagulayan O, Ostrea EM Jr, Dalisay C. The Tagum StudyI: Analysis and clinical correlates of mercury in maternal and cord blood, breastmilk, meconium and infant’s hair. Pediatrics 2000;106:774-781 Rasheed A, Tindall S, Cueny DL, Delaney-Black V: Neurodevelopmental outcome following congenital diaphragmatic hernia: ECMO before and after surgery. J of Pediatric Surgery, in press. Sood BG, Delaney-Black V, Covington C, Nordstrom-Klee B, Ager J, Templin T, Janisse J, Martier S, Sokol RJ: Prenatal alcohol exposure and childhood behavior at age 6-7 years: I Threshhold Effect. Pediatrics, in press. Sorokin Y, Blackwell S, Reinke T, Kazzi SNJ, Berman S, Bryant D: Demographic and intrapartum characteristics of term pregnancies with early onset neonatal seizures. J of Perinatol 21:1-3, 2001. Stark AR, Carlo WA, Tyson JE, Papile LA, Wright LL, Shankaran S, Donovan EF, Oh W, Bauer CR, Saha S, Poole K, Stoll BJ. Adverse effects of early dexamethasone treatment in extremely-low-birth-weight infants. N Engl J Med 2001; 344:95-101. Stevenson DK, Verter J, Fanaroff AA, Oh W, Ehrenkranz RA, Shankaran S, Donovan EF, Wright LL, Lemons JA, Tyson JE, Korones SB, Bauer CR, Stoll BJ, Papile LA. Sex differences in very-low birthweight outcomes: The newborn male disadvantage. Arch Child Dis (in press). Walsh-Sukys MC, Tyson JE, Wright LL, Bauer CR, Korones SB, Stevenson DK, Verter J, Stoll BJ, Lemons JA, Papile L, Shankaran S, Donovan EF, Oh W, Ehrenkranz RA, Fanaroff AA. Persistent pulmonary hypertension of the newborn in the era before nitric oxide: Practice variation and outcomes. Pediatrics 2000; 105:14-20.
Books/Chapters/Reviews (In Press and Published)
Bedard MP: The anatomy, embryology, and physiology of the neonatal airway. In Kuhn JP, ed. Caffey’s Pediatric Diagnostic Imaging, 10th edition. WB Saunders, in press. Bedard MP: The anatomy, embryology, and physiology of the neonatal lung and thorax. In Kuhn JP, ed. Caffey’s Pediatric Diagnostic Imaging, 10th edition. WB Saunders, in press. Bedard MP: The assessment and management of neonates with congenital anomalies. In Evans M, ed. Prenatal Diagnosis. Appleton and Lange, in press. Cepeda EC, Shankaran S: Neonatal resuscitation and emergencies. In Tintinalli JE, Rothstein RJ, Krome RL eds. "Emergency Medicine. A Comprehensive Study Guide." 5th edition, McGraw-Hill, New York, 2000, pages 49-57. Delaney-Black V, Dahr S, Covington C, Sokol RJ: (2000) Illicit Substance Abuse during Pregnancy. in Practical Strategies in Obstetrics and Gynecology. (pp 390-402) Scott B. Ransom (Ed.) W. B. Saunders Co. Koo WWK, Cepeda E. Parenteral nutrition in neonates. In Rombeau JL, Rolandelli RH (eds), Clinical nutrition: Parenteral Nutrition, 3rd Edition. Philadelphia, WB Saunders Company 2000:463-75 Koo WWK. Body composition measurements during infancy. Annals of the New York Academy of Sciences 2000;904:383-392 Koo WWK. Commentary on “Caffeine citrate for the treatment of apnea of prematurity: a double-blind, placebo-controlled study” by Erenberg A, Leff RD, Haack DG, et al. Pharmacotherapy 2000; 20:644-652. Synopsis (In press) Koo WWK. Commentary on “Effect of vitamin A status at the end of term pregnancy on the saturation of retinol binding protein with retinal” by Sapin V, Alexandre MC, Chaib S, et al. Am J Clin Nutr 2000;71:537-543. Synopsis 2000;2(1):49-50 Koo WWK. Commentary on “Vitamin A supplementation for extremely-low-birth-weight infants” by Tyson JE, Wright LL, Oh W, et al. N Engl J Med 1999; 340:1962-8. Synopsis 2000;2(2):52-53 Koo WWK. Commentary on ““The long term effect of early mineral, vitamin D, and breast milk intake on bone mineral status in 9- 11- year old children born prematurely” by Backstrom MC, Maki R, Sievanen H, et al. J Pediatr Gastroenterol Nutr 1999;29:575-82. Year Book of Neonatal-Perinatal Med (In press) Ostrea, EM Jr., Laxa, MT: Prenatal drug abuse and the neonatal abstinence syndrome. In PrimaryPediatric Care. Hoekelman J, Nelson N eds. Mosby-Year Book Publisher, St. Louis, MO 2000 Shankaran S. Amplitude integrated EEG 3 and 6 hours after birth in full term neonates with hypoxic-ischaemic encephalopathy. In Fanaroff AA, Maisels MJ, Stevenson DK eds. “Yearbook of Neonatal and Perinatal Medicine.” 2000 edition, Mosby, Chicago, 2000, pages 138-139. Shankaran S. Complications of neonatal intracranial hemorrhage. NeoReviews 2000; 1:e43-47. Shankaran S. Selection of neonates for neuroprotective therapies: One set of criteria applied to a population. In Fanaroff AA, Maisels MJ, Stevenson DK eds. “Yearbook of Neonatal and Perinatal Medicine.” 2000 edition, Mosby, Chicago, 2000, pages 136-137. Shankaran S. Severe prematurity: Implications and counseling. In Ransom SB, Dombrowski MP, Evans MI ed. “Comtemporary Therapy in Obstetrics and Gynecology Issues and Controversies 2000/2001.” 2000 edition, W. B. Saunders Company, 2000 (in press). Shankaran S. The prediction of fetal acidosis by means of intrapartum fetal pulse oximetry. In Fanaroff AA, Maisels MJ, Stevenson DK eds. “Yearbook of Neonatal and Perinatal Medicine.” 2000 edition, Mosby, Chicago, 2000, page 101.
Abstracts, Letters to the Editor and Articles in Non-Referred Journals Carlo WA, Stark AR, Bauer C, Donovan E, Oh W, Papile LA, Shankaran S, Tyson JE, Wright LL, Temprosa M, Poole K. Effect of minimal ventilation in a multicenter randomized controlled trial of ventilator support and early corticosteroid therapy in extremely low birth weight infants. Pediatr Res 47:391A, 2000. Chambers CD, Braddock S, Briggs J, Einarson A, Johnson Y, Miller R, Polifka J, Robinson L, Stepanuk K, Jones K. Post-marketing Surveillance for Human Teratogenicity: A Novel Approach. Teratology 2000; 61:520A. Covington C, Delaney-Black V, Templin T, Sokol R, Ager J, Nordstrom-Klee B, Martier S: Effects of prenatal smoking and alcohol exposure on child behavior. Pediatr Res 47(4):25A, 2000. Covington C, Nordstrom-Klee B, Delaney-Black V, Templin T, Ager J, Sokol RJ: Validation of an instrument to assess problem behavior in first grade students prenatally exposed to cocaine. AMERSA, November 2000. Delaney-Black V, Covington C, Chugani DC, Nordstrom-Klee B, Chugani HT, Sokol RJ, Ager J, Templin T: Brain Serotonin synthesis in children with prenatal cocaine-exposure and abnormal behavior. Pediatr Res 47(4):25A, 2000. Delaney-Black V, Covington C, Nordstrom-Klee B, Ager J, Sokol RJ, Janisse J: Gender differences in school age behavior problems related to prenatal cocaine exposure. Pediatr Res, in press. Delaney-Black V, Covington C, Nordstrom-Klee B, Templin T, Ager J, Sokol RJ: Prediction of child IQ from three different measures of prenatal alcohol exposure. AMERSA, November 2000. Delaney-Black V, Covington C, Templin T, Ager J, Nordstrom-Klee B, Martier S, Kershaw T, Sokol RJ: Alcohol consumption assessed across pregnancy adversely affects child behavior at school age. Am J Obs/Gyn 182(1):S66, 2000. Delaney-Black V, Covington C, Templin T, Kershaw T, Ager J, Nordstrom-Klee B, Clark N, Surendan A, Martier S, Sokol RJ: Prenatal cocaine and cigarettes associated with poor language development at age 6-years. Am J Obs/Gyn 182(1):S74, 2000. Delaney-Black V, Covington C, Templin T, Kershaw T, Nordstrom-Klee B, Ager J, Clark N, Surendran A, Martier and Sokol R: Prenatal exposures adversely affect childhood language development. Pediatr Res 47(4):146A, 2000. Delaney-Black V, Hansen N, Vohr B, Wright LL, Poole K, Bauer C, Dusick A, Steichen J: Relation of parental perception of extremely low birth weight (ELBW) infant’s functional status to outcome. Pediatr Res, in press. Delaney-Black V, Nordstrom-Klee, Covington C, Ager J, Sokol RJ, Janisse J: Academic achievement of first graders prenatally exposed to cocaine. Pediatr Res, in press. Delaney-Black V, Nordstrom-Klee, Covington C, Ager J, Sokol RJ: Prenatal drug exposure and growth to age 7. Pediatr Res, in press. Einarson A, Lavigne S, Brochu J, Addis A, Matsui D, Johnson Y, Koren G. Pregnancy Outcome Following Exposure to Trazodone and Nefazodone: A Prospective Controlled Multicentre Study. Teratology 2000; 61:521A. LaGasse LL, Messinger D, Lester BM, Seifer R, Bauer CR, Shankaran S, Bada H, Wright L, Smeriglio V, Poole K, Liu E. Prenatal drug exposure & maternal & infant feeding behavior. Pediatr Res 2001 (in press). Laptook AR, Shankaran S, Wogelmuth L. Optimizing control of body and brain temperature during induced whole body hypothermia. Pediatr Res 2001 (in press). Ostrea EM Jr, Whitehall J., Laken M. Prevalence of fetal exposure to environmental toxins: An international study. Pediatr Res 47: 312A, 2000. Posecion JE, Salari V. Ostrea EM Jr. treatment does not decrease the incidence of BPD dysplasia in very low birth weight infants colonized with Ureaplasma urealyticum. Pediatr Res 47:346A, 2000 Shankaran S, Baker JD, Becker C, Canady A, Delaney-Black V. Aggressive management of posthemorrhagic ventriculomegaly (PHVM) may limit morbidity in VLBW infants with grade III ICH. Pediatr Res 47:323A, 2000. Shankaran S, Baker JD, Becker C, Canady A, Delaney-Black V: Aggressive management of posthemorrhagic ventriculomegaly (PHVM) may limit morbidity in VLBW infants with Grade III ICH. Pediatr Res 47(4):323A, 2000. Shankaran S, Laptook AR, Wright LL, Ehrenkranz RA, Donovan EF, Faranroff AA, Stark AR, Tyson JE, McDonald SA, Poole K. Whole body hypothermia for hypoxic-ischemic encephalopathy (HIE) in term infants: Multicenter randomized controlled pilot study of feasibility. Pediatr Res 2001 (in press). Sood B, Delaney-Black V, Covington C, Nordstrom-Klee B, Ager J, Templin T, Janisse J, Martier S, Sokol RJ: Threshold dose of prenatal alcohol to adverse behavioral outcomes. Alcoholism Clinical and Experimental Research, 2000. Sood BG, Delaney-Black V, Covington C, Nordstrom-Klee B, Ager J, Templin T, Janisse J, Martier S, Sokol RJ: Differing threshold dose of prenatal alcohol exposure for adverse behavioral outcomes at 6-7 years of age. Pediatr Res, in press. Sood BG, Delaney-Black V, Covington C, Nordstrom-Klee B, Ager J, Templin T, Janisse J, Martier S, Sokol RJ: Gender specific effect of prenatal alcohol exposure on childhood behavior at 6-7 years. Pediatr Res, in press. Sood BG, Delaney-Black V, Covington C, Nordstrom-Klee B, Ager J, Templin T, Janisse J, Martier S, Sokol RJ: Differing dose-response of prenatal alcohol exposure for behavioral outcomes at age 6-7. Am J Obs/Gyn, in press. Stark AR, Carlo W, Bauer C, Donovan E, Oh W, Papile LA, Shankaran S, Tyson JE, Wright LL, Saha S, Poole K. Serious complications in a randomized trial of early stress dose dexamethasone (DEX) in extremely low birth weight (ELBW) infants. Pediatr Res 47:434A, 2000. Stark AR, Carlo W, Vohr BR, Bauer C, Donovan E, Oh W, Papile LA, Shankaran S, Tyson JE, Wright LL, Saha S, Poole K. Neurodevelopmental outcome and growth at 18-22 months in infants treated with early dexamethasone. Pediatr Res 2001 (in press). Whitehall J, Ostrea EM Jr, Patole S. Fetal exposure to pollutants in Townesville, Australia Detected in Meconium. Pediatr Res 47: 299A, 2000.
Division of Pharmacology and Toxicology Mertineid C, Parker J., Glibetic M., and Aranda JV. Nitric Oxide, prostaglandins and impaired cerebrovascular autoregulation in group B streptococcal neonatal meningitis. Can.J Phys. Pharmacol. 2000, Mar:78:217-27 Glibetic, M. Parker, J. Ofenstein, J., Mariska, V. and J.V. Aranda. Seminars in Perinatology. Group B Streptococcus induction and ibuprofen inhibition of inducible NOS through action of nuclear factor kappa B. Semin. Perinatol., (accepted September,2000 in press April, 2001) Mertineid. C., Parker, J., Glibetic, M., and Aranda, V.J.Nitric Oxide, prostaglandins and impaired cerebrovascular autoregulation in group B streptococcal neonatal meningitis. Can.J Phys. Pharmacol. 2000, Mar:78:217-27 Heidemann, S., Ofenstein, J. and Sarnaik, A. The effect of heat on cytokine production in rat endotoxemia. Crit Care Med 28:1465-1468 2000. Heidemann, S., Ofenstein, J. and Sarnaik, A. Ibuprofen attenuates cardiopulmonary dysfunction by modifying vascular tone in endotoxemia. Prostaglandin Leukotrienes, Essential Fatty Acids 60, No.3:181-85 1999 Ofenstein J, Heidemann S, Wilstermann A, and Sarnaik A, Expression of stress proteins hsp72 & hsp32 in rat spleen cells in response to septic shock, Ann Clin Lab Sci 30, No.1:1-6, 2000. Glibetic M, Samlalsingh-Parker J, Raykova R, Ofenstein JP and Aranda JV. Group B Streptococciand inducible nitric oxide synthase: modulation by nuclear factor kappa B and ibuprofen, Vol 25 No.2: 2001. Aravind MK, Prescilla R, and Ofenstein JP. A rapid and sensitive high-performance liquid chromatography assay of rofecoxib in human serum, J. Chromatogr. B (in press) 2001. White SR, Yadao C. Characterization of Methylphenidate exposures reported to a regional poison control center. Arch Ped Adolescent Med, 154:1199-1203, 2000. White SR, Dy G, Wilson J. The case of the slandered Halloween cupcake: Survival following massive pediatric Procainamide overdose. Pediatric Emergency Care, 2000 (in press).
Books/Chapters/Reviews (In Press and Published) White SR. Carbon monoxide poisoning. In: The Saunder’s Manual of Critical Care (JA Kruse, RW Carlson, MP Fink, eds.), W.B. Saunders Co, 2000 (in press). White SR. Poisoning and drug overdose. In: The Saunder’s Manual of Critical Care (JA Kruse, RW Carlson, MP Fink, eds.), W.B. Saunders Co, 2000 (in press). Abstracts, Letters to the Editor, Articles in Non-Refereed Journals (In Press and Published) Glibetic M, Ofenstein J, Marinska V, and Aranda J.V. Early Action of group B streptococcus (GBS) on human lung epithelial cells: Involvement of inducible Nitric Oxide Synthase (iNOS), Interleukin-8 and Nuclear Factor kappaB. Pediatric Research 2000, 47(4):4;470A Glibetic M., Raykova V, Ofenstein J, and Aranda JV. Role of nuclear factor kappa B and dexamethasone in the in vivo regulation of proinflammatory mediator IL-6. (September/2000 accepted for presentation in Seminars in Perinatal Colloquium, Florida, July, 2001) Prescilla R., Marinska V, Parker J, Glibetic M, and Aranda JV. Ibuprofen and rofecoxib suppress GBS-induced cyclooxigenase-2 gene expression in human lung epithelial cells. Pediatric Research 2000 47(4):4;473A Gharpure, V. Heidemann, S. and Glibetic, M. Heat stress inhibits inducible nitric oxide synthase in rat endotoxemia. Pediatric Research 47(4): 4;56A Glibetic, M., Ofenstein, J., Mariska, V. and Aranda, J.V. Action of group B streptococcus (GBS) on human lung epithelial cells: Involvement of inducible Nitric Oxide Synthase (iNOS), Interleukin-8 and Nuclear Factor kappaB. Pediatric Research 47(4): 4;470A Glibetic, M., Raykova, V., Ofenstein, J. and J.V. Aranda. Role of nuclear factor kappa B and dexamethasone in the in vivo regulation of proinflammatory mediator IL-6. (September/2000 accepted for presentation in Seminars in Perinatal Colloquium, Florida, July, 2001) Heidemann, S. and Glibetic, M. Heat Stress induces MIP-2 production in the lung of endotoxemic rats. Pediatric Research 47(4):4;57A Prescilla, R., Marinska, V., Parker, J., Glibetic, M. and J.V. Aranda. Ibuprofen and rofecoxib suppress GBS-induced cyclooxigenase-2 gene expression in human lung epithelial cells. Pediatric Research 47(4):4;473A Glibetic M, Ofenstein JP, Marinska, V, Action of Group B streptococcus (GBS) on human lung epithelial cells: involvement of inducible nitric oxide synthase (INOS), interleukin-8 and nuclear factor Kappa B. Ped Res 47(4): A1973 Ofenstein J and Wilstermann A, Early protection from endotoxin by heat induced HSP 72 in rats is not mediated by decreasing nitric oxide synthesis. Ped Res 47(4): A2776 2001. Ofenstein JP, Glibetic M, Raykova V, and Aranda JV. In vivo anti-inflammatory effect of CAPA, an non-steroidal Nuclear kappa B inhibitor, via suppression of Nitric Oxide Synthase induction. Soc Ped Res. Baltimore, MD, April 2001. Raykova V, Ofenstein JP, Aranda JP, and Glibetic M. Nitric Oxide-dependent regulation of interleukin (IL)-6 and MIP-2 inGroup B Streptococcal lung inflammation. Soc Ped Res. Baltimore, MD, April 2001. Glibetic M, ,Raykova V, Ofenstein JP, and Aranda JV. In vivoregulation of pro-inflammatory mediator IL-6: Role of nuclear factor kappa B and dexamethasone. Soc Ped Res. Baltimore, MD, April 2001. White SR. Date rape and club drugs. Michigan Poison System Update Statewide Newsletter, Spring 2000. White SR. Abuse of inhalants. Audio Digest Family Practice, Vol 48(18), May 14, 2000. White SR. Date rape dDrugs: Parts I and II. Featured article on emedhome.com, June 12 and 19, 2000. White SR. Biological & chemical terrorism: Are you ready? News and Views, Michigan College of Emergency Physicians, Vol XIX (6), July/August, 2000. White SR, Baltarowich L, Warfield S, Smolinske S, Scott D. Fatal pneumonitis in a child following aspiration of a high viscosity hydrocarbon. Clin Toxicol 2000, (in press). Division of Ambulatory
Pediatrics and Adolescent Medicine Sylwestrzak MS, Fischer BF, Fischer H. Recurrent clitoral tourniquet syndrome, Pediatrics 105(4); 866-867, 2000. Fiore, M, Fischer H. Morning report at Children’s Hospital of Michigan: Mediastinal mass in a 9-year-old girl. Synopsis: A Current survey of world literature in pediatrics. 2; 66-72, 2000. Schuh LM, Schuster CR, Hopper JA, Mendel CM: Abuse liability assessment of sibutramine, a novel anorectic agent. Psychopharmacology 147:339-346, 2000. (Conception, design, revision, approval, technical expertise). Hopper JA, Craig KA: Environmental Tobacco Smoke Exposure in Urban Children. Pediatrics 106(4):e47, 2000. Barnes L, Piotnikoff G, Fox K, Pendleton S. Spirituality, religion, and pediatrics: intersecting worlds of healing. Pediatrics, 106(4): October 2000; 899-908. Pendleton S, Ross K, Pargament K, Nasr S. Religious/spiritual coping in childhood cystic fibrosis: a qualitative study. Submitted Pediatrics. October 2000. Accepted December 2000. Schubiner H, Tzelepis A, Kelley B, Lockhart N, Kruger M, Schoener E. Prevalence of Attention Deficit/Hyperactivity Disorder and Conduct Among Substance Abusers. Journal of Clinical Psychiatry 2000;61:244-251. Melgar T, Schubiner H, Burack R, Aranha A, Musial J. Activities of the attending physicians in an Internal Medicine and Med-Peds resident continuity clinic. Academic Medicine, November 2000. 75:1138-1143, 2000. Schuh KJ, Schubiner H, Johanson CE. Discriminability of intranasal cocaine. Behavioral Pharmacology. 2000;11:511-515. Sawni-Sikand A, Schubiner H, Thomas RL. Use of complementary/alternative therapies among children in primary care pediatric practices. (submitted) Archives of Pediatrics and Adolescent Medicine. Schuh KJ, Schubiner H, Johanson CE. Discrimination of Intranasal Cocaine: Effects of Intranasal Benzocaine. In Problems of Drug Dependence, 2000: Proceedings of the 61st Annual Scientific Meeting of the College on Problems of Drug Dependence, Inc. In Government Printing Office. September 2000, 11(6): 511-5. Schuh KJ, Schubiner H, Johanson CE. Discrimination of Intravenous Cocaine in Humans. In Problems of Drug Dependence, 2000: Proceedings of the 61st Annual Scientific Meeting of the College on Problems of Drug Dependence, Inc. In L.S. Harris (Ed.) NIDA Research Monograph #__. Washington, DC: US Government Printing Office, p. _. Wright K, Neumark-Sztainer D. Guidelines for adolescent female nutrition and implications for women’s health. In Kowalczyk (ed): Infertility and Reproductive Medicine Clinics of North America, April, 2000. Wright K. HIV and Adolescents. In Eyler AE (ed): Adolescent Health Clinics in Family Practice, December 2000, Vol. 2 #4. Books, Chapters and
Reviews Abstracts, Letters to the
Editor and Articles in Non-Refereed Journals
Division of Pulmonary Medicine Schuh LM, Downey KK, Hopper JA, Tancer M: Fluoxetine in Smoking Cessation Treatment. College on Problems of Drug Dependence, Annual Meeting June 2000 (San Juan, Puerto Rico).
Books, Chapters and Reviews Valentini RP and Toder DS. Wegener Granulomatosis. In: Emedicine Pediatrics (SR Neish ed), Emedicine, Inc, 2000. Toder DS. Respiratory Problems in the Adolescent with Developmental Disabilities. In: Pulmonary Disorders in the Adolescent (DN Homnick and DE Greydanus, eds), Adolescent Medicine: State of the Art Reviews. October 2000. Abduhamid IF and Toder DS. Pleural Effusion. In: Emedicine Pediatrics (SR Neish, ed), Emedicine, Inc. 2000. Abdulhamid I. Stridor in Childhood. Synopsis: A Current Survey of World Literature in Pediatrics, 2:6-14, 2000. Abdulhamid IF. Somato Form Disorder: Munchhausen Syndrome by Proxy. In: Pediatrics: An On-line Medical reference 1st Edition (S Altschuler, et.al., ed), Emedicine On-line Textbooks, Emedicine.com, Inc. www.emedicine.com/ped/index.Shtml, St. Petersburg, 2000. Abdulhamid I. Pleural Effusion. In: Pediatrics: An On-line Medical reference 1st Edition (S Altschuler, et.al., ed), Emedicine On-line Textbooks, Emedicine.com, Inc. www.emedicine.com/ped/index.Shtml, St. Petersburg, 2000. Abdulhamid I and Rabah R: Granular Cell Tumor of the Bronchus in a Child. Pediatr Pulmonol 2000;30:425-428. |
2000
Report to Investors: The Quest to Improve Women's Health Gifts from Faculty, Staff, Friends and Corporations 2000/2001 Alumni Annual Telefund Volunteers 2000 New Endowed Funds at the School of Medicine Bibliographies: Barbara Ann Karmanos Cancer Institute Biochemistry and Molecular Biology Center for Healthcare Effectiveness Research Center for Molecular Medicine and Genetics Physical Medicine and Rehabilitation |