Department of Immunology and Microbiology

Chair: Paul Montgomery, PhD
7374 Scott Hall
(313) 577-1591  

Articles

Chen Y, Boros DL. Polarization of the immune response to the single immunodominant epitope of p38, a major schistosoma mansoni egg antigen, generates Th1 or Th2-type cytokines and granulomas. Infect Immun 67:4570-4577, 1999.

Boros DL. T helper cell populations, cytokine dynamics and pathology of the schistosome egg granuloma. Microbes and Infect 1:511-516, 1999.

Boros DL, Whitfield JR. Enhanced Th1 and dampened Th2 responses synergize to inhibit acute granulomatous and fibrotic responses in murine schistosomiasis mansoni. Infect Immun 67:1187-1193, 1999.

Diebel LN, Liberati DM, Diglio CA, Dulchavsky SA, Brown WJ. Synergistic effects of Candida and Escherichia coli on gut barrier function. J Trauma: Injury, Infect Crit Care 47:1045-1051, 1999.

Diebel LN, Liberati DM, Dulchavsky SA, Diglio CA, Brown WJ. Synergistic effect of hyperoxia and immunoglobulin A on mucosal barrier defense. J Trauma 48:37-42, 1999.

Weingarten CM, Rybak MJ, Jahns BE, Stevenson JG, Brown WJ, Levine DL. Evaluation of Acinetobacter baumannii infection and colonization, and treatment patterns in an urban teaching hospital. Pharmacotherapy 19:1080-1085, 1999.

Freitag NE, Jacobs KE. Examination of Listeria monocytogenes intracellular gene expression using the green fluorescent protein of Aequoria victoria. Infect Immun 67:1844-1852, 1999.

Teitelbaum R, Cammer M, Maitland ML, Freitag NE, Condeelis J, Bloom BR. Mycobacterial infection of macrophages results in membrane-permeable phagosomes. Proc Natl Acad Sci USA 96:15190-15195, 1999.

Williams JR, Thayyullathil C, Freitag NE. Sequence variations within PrfA DNA binding sites and effects on Listeria monocytogenes virulence gene expression. J Bacteriol (in press).

Galy A, Christopherson I, Ferlazzo G, Liu G, Spits H, Georgopoulos K. Distinct signals control the hematopoiesis of lymphoid-related dendritic cells. Blood 95:128-137, 1999.

Ferlazzo G, Klein J, Paliard X, Wei W-Z, Galy A. Dendritic cells generated from CD34+ progenitor cells with flt3-ligand, c-kit-ligand, GM-CSF, TNF-alpha and Il-4 are functional antigen-presenting cells resembling mature monocyte-derived DC. J Immunotherapy 23:48-58, 1999.

Ferlazzo G, Wesa A, Wei, W-Z, Galy A. Dendritic cells generated either from CD34+ progenitor cells or from monocytes differ in their ability to activate antigen-specific CD8+ T cells. J Immun 163:3597-3604, 1999.

Wei WZ, Shi WP, Galy A, Lichlyter D, Hernandez S, Groner B, Heilbrun L, Jones RF. Protection against mammary tumor growth by vaccination with full length modified human ErbB-2 DNA. Int J Cancer 81:748-754, 1999.

Chiu C-H, Gregoire L, Gumucio DL, Muniz JA, Lancaster WD, Goodman M. The fetal recruitment of simian gamma-globin genes: insights from two new world monkeys Cebus apella and Callithrix jacchus (Platyrrhini, primates). J Exp Zoology 285:27-40, 1999.

Rabah R, Lancaster WD, Thomas R, Gregoire L. HPV-11 associated recurrent respiratory papillomatosis is more aggressive than HPV-6 associated disease. Ped Develop Pathol (in press).

Rabah R, Sakr W, Thomas R, Lancaster WD, Gregoire L. Human papillomavirus type, proliferative activity and p53: potential markers of aggressive papillomatosis. Arch Pathol Lab Med (in press).

Hazlett LD, Masinick-McClellan SA, Barrett RP. Complement defects in aged mice compromise phagocytosis of Pseudomonas aeruginosa. Curr Eye Res 19:26-32, 1999.

Hazlett LD, McClellan SM, Dajes JJ, Hume EBH, OÕCallaghan RJ, Willcox MDP. Extended wear contact lens usage induces Langerhans cell migration into cornea. Exp Eye Res 69:575-577, 1999.

Kernacki KA, Barrett R, Hazlett LD. Evidence that TIMP-1 is protective against P aeruginosa-induced corneal ulceration and perforation. Invest Ophthalmol Vis Sci 40:3168-3176, 1999.

Newland TJ, McDermott ML, Hazlett LD, Apple DJ, Lambert RJ. Experimental neodymium: YAG laser damage to acrylic, PMMA and silicone intraocular lens materials. J Cataract and Refractive Surgery 25:72-76, 1999.

Hazlett LD, McClellan A, Kwon B, Barrett R. Increased severity of P aeruginosa corneal infection in strains of mice designated as Th1 vs Th2 responsive. Invest Ophthalmol Vis Sci (in press).

Kurpakus MA, Kernacki KA, Hazlett LD. Corneal cell proteins and ocular surface pathology: A review. Biotechnic and Histochemistry (in press).

Heppner GH, Wolman SR. MCF-10AT: A model for human breast cancer development. The Breast J 5:122-129, 1999.

Heppner GH, Wolman SR, Rosen J, Solomon D, Smith G, Mohla S. Meeting Report: Research potential of a unique xenograft model of human proliferative breast disease. Breast Cancer Res and Treatment 58:183-186, 1999.

Miller FR, Heppner GH. Xenograft models of human breast cancer lines and the MCF10AT model of human premalignant, proliferative breast disease. J Mammary Gland Biol and Neoplasia (in press).

Hobden JA, Masinick-McClellan SA, Barrett RP, Bark KS, Hazlett LD. Pseudomonas aeruginosa keratitits in knockout mice deficient in intercellular adhesion molecule-1 (ICAM-1) expression. Infect Immunol 67:972-975, 1999.

Kernacki KA, Barrett R, Hobden J, Hazlett LD. MIP-2 is a mediator of PMN influx in ocular bacterial infection. J Immunol 164:1037-1045, 1999.

Estrellas Jr PS, Alionte LG, Hobden JA. A Pseudomonas aeruginosa strain isolated from a contact lens-induced acute red eye (CLARE) is protease-deficient. Curr Eye Res (in press).

Arking EJ, Appelt DM, Abrams JT, Kolbe S, Hudson AP, Balin BJ. Ultrastructural analysis of Chlamydia pneumoniae in the AlzheimerÕs brain. Pathogenesis 1:201-211, 1999.

Gerard HC, Wang GF, Balin BJ, Schumacher HR, Hudson AP. Frequency of apolipoprotein E (APOE) allele types in patients with Chlamydia-associated arthritis and other arthritides. Microb Pathogen 26:35-43, 1999.

Henry CH, Hudson AP, Gerard HC, Franco PF, Wolford LM, Identification of Chlamydia trachomatis in the human temperomandibular joint. J Oral Maxillofac Surg 57:683-688, 1999.

Kotake S, Schumacher HR, Arayssi TK, Gerard HC, Branigan PJ, Hudson AP, Yarboro CH, Klippel JH, Wilder RL. IFN-gamma, IL-10 and IL-12 p40 gene expression in synovial tissues from patients with recent-onset Chlamydia-associated arthritis. Infect Immun 67:2682-2686, 1999.

Nevel-McGarvey CA, Levin RM, Hudson AP. Transcription of mitochondrial and mitochondria-related nuclear genes in rabbit urinary bladder following release from partial outlet obstruction. Mol Cell Biochem 197:161-172, 1999.

Schumacher HR, Arayssi TK, Crane M, Lee J, Gerard HC, Hudson AP, Klippel JH. Chlamydia trachomatis nucleic acids can be found in synovium of some asymptomatic volunteers. Arthritis Rheum 42:1281-1284, 1999.

Schumacher HR, Gerard HC, Arayssi TK, Pando JA, Branigan PJ, Saaibi DL, Hudson AP. Chlamydia pneumoniae is present in synovial tissue of arthritis patients with lower prevalence than that of C trachomatis. Arthritis Rheum 42:1889-1893, 1999.

Whittum-Hudson JA, Gerard HC, Clayburne G, Schumacher HR, Hudson AP. A non-invasive murine model of reactive arthritis. Rev Rhum (Engl ed) 66(#1 suppl):50S-56S, 1999.

Cheema MA, Rahman MU, Whittum-Hudson JA, Hudson AP. Cervical Chlamydia trachomatis in women at low risk for infection. Am J Med Sci (in press).

Mueller AJ, Folberg RN, Freeman WR, Bartsch D-U, Bergeron-Lynn G, Mehaffey MG, Kan-Mitchell J, Huang X, Jian G, Avila C, Taskintuna I, Cheng L, Wang J. Evaluation of the human choroidal melanoma rabbit model for studying microvascularization patterns with confocal ICG and histology. Exp Eye Res 68:671-678, 1999.

Gruber A, Kan-Mitchell J, Kuhen KL, Mukai T, Wong-Staal F. Efficient and non-disturbing transduction of dendritic cells by HIV-1 vectors to elicit HIV specific T-lymphocytes in vitro. Blood (in press).

Mitchell MS, Jones VE, Kan-Mitchell J, Darrah D, Huang WQ, Waterfield M, Previde P, Kehoe M. Reddish MA, MacLean G, Parker J, Meikle A, Longenecker BM. Active specific immunotherapy of breast cancer: phase I study of a conjugated 16 amino acid MUC1 peptide (BP16-KLH) and DETOXO-B-SE adjuvant. Clin Cancer Res (in press).

Abdulamid I, Kassab MS, Beck FWJ, Kaplan J, Prasad AS. Zinc status and interleukin-2 production in cystic fibrosis. J Trace Elem Exp Med 12:15-23, 1999.

Prasad AS, Beck FWJ, Kaplan J, Chandrasekar PH, Ortega J, Fitzgerald JT, Swerdlow P. Effect of zinc supplementation on incidence of infections and hospital admissions in sickle cell disease. Am J Hematol 61:194-202, 1999.

Chou S-R, Brownell A, Ko M, Kaplan J. Interferon gamma receptors polymophisms determine strain differences in accessibility of activated lymphocyte NK-triggering antigens to recognition by self-reactive NK cells. Cell Immunol (in press).

Dai Y, Carayanniotis KA, Eliades P, Lymberi P, Shepherd P, Kong YM, Carayanniotis G. Enhancing or suppressive effects of antibodies on processing of a pathogenic T-cell epitope in thyroglobulin. J Immunol 162:6987-6992, 1999.

Wan Q, Shah R, McCormick DJ, Lomo LC, Giraldo AA, David CS, Kong YM. H2E transgenic class II-negative mice can distinguish self from nonself in susceptibility to heterologous thyroglobulins in autoimmune thyroiditis. Immunogenetics 50:22-30, 1999.

Loeffler DA, Linder MC, Zamany M, Harel E, Paul M, Baumann H, LeWitt PA. Acute phase proteins in the rat brain: contribution of cerebrovascular contents. Neurochem Res 24:1313-1317, 1999.

Loeffler DA, Camp DM, Juneau PL, LeWitt PA. Purine-induced alterations of dopamine metabolism in PC12 rat pheochromocytoma cells. Brain Res Bull (in press).

Camp DM, Loeffler DA, LeWitt PA. Levodopa does not enhance hydroxyl radical formation in the nigrostriatal dopamine system of rats with a unilateral 6-hydroxydopamine lesion. J Neurochem (in press).

Roberts PC, Kipperman T, Compans RW. Vesicular stomatitis virus G protein acquires pH-independent fusion activity during transport in a polarized endometrial cell line. J Virol 73(12):10447-10457, 1999.

Balachandran S, Roberts PC, Bhalla KN, Bramlet EA, Baxa AC, Compans RW, Archer DR, Barber GN. Loss of functional PKR enhances in vivo susceptibility to virus infection in mice. Immunity (in press).

Balachandran S, Roberts PC, Kipperman T, Bhalla KN, Compans RW, Archer DR, Barber GN.  Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway. J Virol (in press).

Schmelz EM, Roberts PC, Kustin EM, Hill RL, Dillehay DL, Merrill Jr AH. Sphingolipids control the distribution of intestinal beta-catenin and suppress tumorigenesis in mice with genetic and chemically induced APC gene mutations. Science (in press).

Ben-Josef AV, Manavathu EK, Platt D, Sobel JD. Involvement of calcium inhibitable binging to the cell wall in the fungicidal activity of CAN-296. J Antimicrob Chemo 44:217-222, 1999.

Klein RS, Sobel JD, Flanigan T, Smith D, Margolick JB, HIV Epidemiology Research Study Group. Stability of cutaneous anergy in women with or at risk for HIV infection. J Acquired Imm Def Synd and Human Retrovir 20:238-244, 1999.

Saag M, Cloud GA, Graybill JR, Sobel JD, et al. A comparison of itraconazole versus fluconazole as maintenance therapy for AID-associate Cryptococcal meningitis. Clin Infect Dis 28:291-296, 1999.

Sarma AV, Foxman B, Bagirli B, Haefner H, Sobel JD. Epidemiology of vulvar vestibulitis syndrome: an exploratory case control study. Sex Trans Infect 75:320-326, 1999.

Silverman J, Vazquez JA, Sobel JD, Zervos MJ. Comparative in vitro activity of antiseptics and disinfectants versus clinical isolates of Candida species. Infect Control and Hosp Epidemiol 20:676-684, 1999.

Vazquez JA, Sobel JD, Peng G, Steele-Moore L, Schuman P, Holloway W, Neaton J, for the Terry Beirn Community Program for Clinical Research in AIDS (CPCRA). Evolution of vaginal Candida species recovered for HIV-infected women receiving fluconazole prophylaxis: The emergence of Candida glabrata? Clin Infect Dis 28:1025-1031, 1999.

Yoon SA, Vazquez JA, Steffan PE, Sobel JD, Akins RA. High frequency, in vitro reversible switching of Candida lusitaniae clinical isolates from amphotericiin B-susceptible to resistance. Antimicrob Agents Chemother 43:836-45, 1999.

Foxman B, Barlow R, dÕArcy H, Gillespie B, Sobel JD. Candida vaginitis: Self-reported incidence and associated costs. Sex Trans (in press).

Foxman B, Barlow R, dÕAray H, Gillespie B, Sobel JD. Tract infection: Self-reported incidence and associated costs. Ann Epidemiol (in press).

Foxman B, Gillespie B, Koopman J, Zhang L, Palin K, Tallman P, Marsh JV, Spear S, Sobel JD, Marty MJ, Marr CF. Risk factors for second urinary tract infection among college women. Am J Epidemiol (in press).

Graybill JR, Sobel JD, Saag M, VanderHorst C, Powderly W, Cloud G, Riser L, Hamill R, Dismukes W. Diagnosis and management of increased intracranial pressure in patients with AIDS and cryptococcal meningitis. Clin Infect Dis (in press).

Hillier SL, Schwebke JR, Sobel JD, McGregor JA, Sweet RL. Clinical evaluation of the FemExam Testcard for detection of elevated pH and trimethylamine. Sex Trans Dis (in press).

Kaufmann C, Vazquez JA, Sobel JD, Gallis HA, McKinsey DS, Karchmer AW, Sugar AM, Sharkey PK, Wise GJ, Mangi R, Mosher A, Lee JY, Dismukes WE and the NIAID Mycoses Study Group. A prospective multicenter surveillance study of funguria in hospitalized patients. Clin Infect Dis (in press).

Klein RS, Smith D, Sobel JD, Flanigan T, Margolick JB. A prospective study of positive tuberculin reactions in women with or at risk for HIV infection. Int J TB and Lung Dis (in press).

Klein RS, Sobel JD, Flanigan T, Smith D, Marolick JB. Stability of cutaneous anergy in women with or at risk for HIV infection. J Acquir Immun Def Synd and Hum Retrovir (in press).

Manavathu EK, Ben-Josef AV, Sobel JD. Proton translocating ATPase mediated fungicidal activity of a novel complex carbohydrate: CAN-296. Int J Antimicrob Ag (in press).

Sobel JD, Kauffman CA, McKinsey D, Zervos D, Vazquez JA, Panzer H, Dismukes W. Candiduria in a randomized double blind study of treatment with fluconazole and placebo. Clin Infect Dis (in press).

Stepaniak JA, Shuster JE, Hu W, Sundick RS. Production and in vitro characterization of recombinant chilken IL-2. J Intereferon and Cytokine Res 19:515-526, 1999.

Lenz DC, Wolf NA, Swanborg RH. Strain variation in autoimmunity: Attempted tolerization of DA rats results in the induction of experimental autoimmune encephalomyelitis. J Immunol 163:1763-1768, 1999.

Smeltz RB, Wauben MHM, Wolf NA, Swanborg RH. Critical requirement for aspartic acid at position 82 of myelin basic protein 73-86 for recruitment of Vb8.2+ T cells and encephalitogenicity in the Lewis rat. J Immunol 162:829-836, 1999.

Smeltz RB, Wolf NA, Swanborg RH. Inhibition of autoimmune T cell responses in the DA rat by bone marrow-derived natural killer cell in vitro: Implications for Autoimmunity. J Immunol 163:1390-1399, 1999.

Shibuya TY, Wei W-Z, Zormeier M, Ensley J, Sakr W, Mathog R, Meleca RJ, Yoo G, June CH, Levine B, Lum LG. Anti-CD3/anti-CD28 Mo Ab coated suture enhances HNSCC patients immune responses. Arch Otolaryngology-Head Neck Surgery 125:1229-1234, 1999.

Baynes RD, Dansey RD, Klein JK, Karanes C, Abella E, Cassells L, Wei WZ, Galy A, Wood G, Peters WP. High dose chemotherapy and peripheral blood progenitor cell transplantation in patients with breast cancer. Cancer Invest (in press).

Ferlazzo G, Klein J, Paliard X, Wei W-Z, Galy A. Dendritic cells generated from CD34+ progenitor cells with flt3-ligand, c-kit ligand, GM-CSF, IL-4 and TNF-alpha are functional antigen-presenting cells resembling mature monocyte-deerived DC. J Immunotherapy (in press).

Shibuya TY, Wei W-Z, Zormeier M, Ensley J, Sakr W, Mathog R, Melecca RJ, Yoo G, June CH, Levine B, Lum LG. Anti-CD3/anti-CD28 bead overcomes T cell unresponsiveness in HNSCC patients. Archives of Otolaryngology-Head Neck Surgery (in press).

Whittum-Hudson JA. Prevention vs treatment of Chlamydial infections: A novel experimental approach. Current Treatment Options in Infectious Disease 1:88-92, 1999.

Unman R, Whittum-Hudson JA, Schumacher HR, Hudson AP. Chlamydia and Reactive Arthritis. Curr Opin Arthritis (in press).

Jabs DA, Lee B, Whittum-Hudson JA, Prendergast RA. Th1 vs Th2 immune responses in autoimmune lacrimal gland disease in MRL/Mp mice. Invest Ophthalmol Vis Sci (in press).

Traboulsi, EI, Whittum-Hudson JA, Mir S, Hussells IM. Further association of defective fibrillin expression in patients with Marfan Syndrome and lens abnormalities. Ophthalmic Genet (in press).

Chadha HS, Fitzgerald RH, Wiater P, Sud S, Nasser S, Wooley PH. Experimental acute hematogenous osteomyelitis in mice. I. Histopathological and Immunological Findings. J Orthopaedic Res 17:376-381, 1999.

Schaefer CJ, Lawrence WD, Wooley PH. The influence of long term silicone implantation on type II collagen-induced arthritis in mice. Anns Rheum Dis 58:503-509, 1999.

Schaefer CJ, Wooley PH. The influence of silicone implantation on murine lupus in MRL lpr/lpr mice. J Rheumatology 26:2215-2221, 1999.

Wooley PH, Fitzgerald RH, Song Z, Davis P, Whalen JD, Trumble S, Nasser S.  Antibodies to implant bound proteins are a frequent finding in patients with aseptic loosening of the total joint arthroplasty. J Bone Joint Surgery 81A:616-623, 1999.

Yoon KS, Fitzgerald RH, Sud S, Song Z, Wooley P H. Experimental acute hematogenous osteomyelitis in mice.  II. Influence of Staphylococcus aureus infection upon T cell immunity. J Orthopaedic Res 17:381-391, 1999.

Nelson DA, Vandevord P, Wooley PH. Polymorphism in the vitamin D receptor gene and bone mass in African-American and White mothers and children: A preliminary report. Ann Rheum Dis (in press).

Yoshimura FK, Wang T, Cankovic M. Sequences between the enhancer and promoter in the long terminal repeat affect murine leukemia virus pathogenicity and replication in the thymus. J Virology 73:4890-4898, 1999.

Books, Chapters and Reviews

Freitag NE. Genetic tools for use with Listeria monocytogenes. In: The Gram-Positive Pathogenes, (Ferretti JJ, Novick RP, Rood J, Portnoy DE, eds.), Am Soc Microbiol, Washington, DC, p 488-498, 1999.

Galy A. Generation of dendritic cells from lymphoid precursors. In: Dendritic cell protocols. Methods in molecular medicine, (Stagg, Robinson, eds.), Humana Press (in press).

Kernacki KA, Hobden JA, Hazlett LD. Murine model of bacterial keratitis. In: Handbook of Animal Models of Infection. (Zak O, Sande M, eds.), Academic Press, London, UK, 41:361-366, 1999.

Gerard HC, Whittum-Hudson JA, Balin BJ, A ppelt DM, Hudson AP. Chlamydia pneumonia, APOE genotype, and AlzheimerÕs disease. In: Proceedings of the State-of-the-Art Workshop. Chlamydial Basis of Chronic Diseases, the Robert Koch Institute, Berlin (in press).

Nevel-McGarvey CA, Levin RM, Wu X, Haugaard N, Hudson AP. Mitochondrial involvement inbladder function and dysfunction. Mol Cell Biochem 194:1-15, 1999.

Gerard HC, Whittum-Hudson JA, Appelt DM, Balin BJ, Hudson AP. Chlamydia pneumoniae, APOE genotype, and AlzheimerÕs disease. Proceedings of RKI State-Of-The-Art Workshop: Chlamydia pneumoniae and chronic diseases. Robert Koch Institute, Berlin, Germany (in press).

Nevel-McGarvey CA, Levin RM, Wu X, Haugaard N, Hudson AP. Mitochondrial involvement in bladder function and dysfunction. Mol Cell Biochem 194:1-15, 1999.

Kong YM. Experimental model for autoimmune thyroid disease: Recent developments. In: Contemporary Endocrinology on Autoimmune Endocrinopathies, (Volpe R, ed.), Humana Press, Totowa, NJ, p 91-111, 1999.

Minev BR, Chavez F, Mitchell MS. Cancer vaccines: Novel approaches and new promises. Pharmacology and Therapeutics 81:121-139, 1999.

Mitchell MS, Press MP. The role of immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) for HER-2/neu in assessing the prognosis of breast cancer. Semin Oncol 26:S12:108-116, 1999.

Sobel JD. Biotherapeutic agents as therapy for caginitis. In: Probiotic Therapy. (Elmer GW, McFarland LV, Surawicz CM eds.), Humana Press, Totowa, NJ, p 221-244, 1999.

Sobel JD. Urinary tract infections. Uncomplicated, complicated, and nosocomial. In: Current Practice of Medicine, (Fitzgerald FT, ed.), Vol 2 No 4 Chapter 164:555-562, 1999.

Obel JD, Vazquez J. Fungal infections of the urinary tract. In: Comprehensive clinical Nephrology, (Johnson RJ, Feehally J, eds.), Mosby Int, Chapter 58 Section 10 p 58.1-58.6, 1999.

Fidel Jr PL, Sobel JD. Murine models of Candida vaginal infection. In: Handbook of Animal Models of Infection, (Zak O, Sande M, eds.), Academic Press, Guersney, UK (in press).

Lundstrom TS, Sobel JD. Fungal infections. In: Association for Professionals, Infect Cont Epid Curr, (Olmstead R, ed.), Mosby Year Book Publishers, Chicago, IL (in press).

Lundstrom TS, Sobel JD. Vancomycin, Teicoplanin, Quinupristin/Dalfopristin and Linezolid. In: Infectious Disease Clinics of North America, (Kaye D, ed.) (in press).

Sobel JD. Candida vaginitis. In: Infectious Diseases in Obstetrics and Gynecology, (Faro S, Maartens M, Soper D, eds), WB Saunders (in press).

Sobel JD. Candida vaginitis. In: Vulvovaginal disease, (Ledger W, Witkin J, eds.), W.B. Saunders Co., New York, NY (in press).

Sobel JD. Fungal infections of the genitourinary tract. In: Clinical Mycology (Anaissie E, McGinnis M, Pfaller M, eds.), WB Saunders (in press).

Sobel JD. Genital candidosis. In: International Standard Book for Infectious Diseases in Obstetrics, Gynecology, Dermatology, Urology, and Clinical Immunology, (Weissenbacher ER, ed.), Medifact Publishing House, Munich, Germany (in press).

Sobel JD, Candiduria. In: Current Therapy of Infectious Diseases, (Schlossberg D, ed.), Mosby Year Book, Philadelphia, PA (in press).

Sobel JD. Cervicitis. In: American College of Physicians (in press).

Sobel JD. Mucocutaneous candidiasis. In: Fungal Infections (Diamond R, ed.), Atlas of Infectious Diseases (in press).

Sobel JD, Vaginitis. In: American College of Physicians (in press).

Sobel JD. Vulvitis, vaginitis and cervicits. In: Infectious Disease (Armstrong D, Cohen J, eds.), Mosby, London, UK (in press).

Sobel JD. Vulvovaginal candidosis. In: Medicine, UK (in press).

Sobel JD, Kaye D. Urinary tract infections. In: Principles and Practice of Infectious Diseases, (Mandell G, Bennett J, Dolin R, eds), Churchill Livingston, Philadelphia, PA. (in press).

Fidel Jr PL, Vazquez JA, Sobel JD. Candida glabrata: Review of epidemiology, pathogenesis and clinical disease. Clinic Micro Rev 12:80-96, 1999.

Sobel JD. Asymptomatic candiduria, a review of treatment. Int J Antimicrobial Ag 11:285-288, 1999.

Sobel JD. Diagnostic considerations in microscopy-negative Candida vaginitis. Ital J Gynecol Obstet 2:73-78, 1999.

Sobel JD. Limitations of antifungal agents in the treatment of Candida vaginitis: future challenges. Drug Resistance Updates 2:148-153, 1999.

Sobel JD. Vulvovaginitis in healthy women. Comprehensive Ther 25:335-346, 1999.

Sobel JD, Vazquez JA. Urinary tract infections due to fungi. World J Urology 17:410-414, 1999.

Rex JH, Walsh TJ, Sobel JD, Filler SG, Pappas PG, Dismukes WE. Edwards JR. Treatment guidelines for candidiasis. Clin Infect Dis (in press).

Saag MS, Graybill JR, Larsen RA, Pappas PG, Perfect JR, Powderly WG, Sobel JD, Dismukes WE. Guidelines for the management of cryptococcal disease. Clin Infect Dis (in press).

Sobel JD. Bacterial vaginosis. Ann Rev Med (in press). 

Sobel JD. Diagnostic strategems in the management of  patients with acute and chronic vaginitis. Contemporary Obstet (Canada) (in press).

Sobel JD. Protective role of vaginal flora. Curr Infect Dis Reports 1:379-383, 1999.

Sobel JD. Treatment of fungal disease in pregnancy. AIDS Publication (in press).

Sundick RS, Stepaniak JA, Shuster JE, Hu W. Lymphokines. In: Encyclopedia of Molecular Biology, (Creighton TE, ed.), John Wiley and Sons, NY, p 1415-1417, 1999.

Lenz DC, Swanborg RH. Suppressor cells in demyelinating disease: A New Paradigm for the New Millennium. J Neuroimmunol (in press).

Wei W-Z, Pitchocki M, Pilon S, Kelly C. erbB-2 DNA vaccines. Biolab Tech Int (in press).

Abstacts

Berk RS, Ghabrial M, Yang M, Kurkinen M. Detection and characterization of MMP and TIMP expression in mice intracorneally infected with Pseudomonas aeruginosa. Invest Ophthal Vis Sci S259, 1999.

Lundy SK, Boros DL. Egg antigen induced T helper lymphocyte apoptosis correlates with Fas ligand expression during murine infection with schistosome mansoni. FASEB J 13:A980, 1999.

Brown WJ, Marsilio MK, Piazza G, Tomfohrde KM. Use of an electronic surveillance database to compare antimicrobial susceptibility profiles of clinical isolates from community and teaching hospitals. Am Soc Microbiol C284, 1999.

Brown WJ, Piazza G, Marsilio MK, Heller BH. Use of TSN database to compare the antimicrobial susceptibility profiles of common pathogens isolated from children and adults. Am Soc Microbiol C283, 1999.

Diebel LN, Dulchavsky SA, Diglio CA, Brown WJ. The synergistic effect of ethanol and tissue hypoxia on enyterocyte production of proinflammatory cytokines. Am Ass Surg Trauma 59:13-12, 1999.

Hidalgo J, Akins RA, Brown W, Vazquez JA. Invasive Candida dubliniensis infection in a non-HIV positive patient. Verification with RAPD and a species-specific probe. IDSA 37:216, 1999.

Shieh M, McKinnon PS, Akins R, Brown WJ, Rybak MJ. Pharmacodynamic (PD) comparison of fluoroquinolones (FQ) against clinical isolates of Pseudomonas aeruginosa (PA) and Streptococcus pneumoniae (SP). ICAAC 39, 1999.

Tolia V, Brown W, El-Baba M, Peters J, Lin CH. Antimicrobial susceptibility of Helicobacter pylori (Hp) from children with gastritis in Michigan. Ann Sci Meeting Am Col Gastroenterol, Phoenix, AZ, 1999.

Freitag NE. Microbial pathogenesis and host defense. Cold Spring Harbor Meeting, Cold Spring Harbor, NY, 1999.

Greene SL, Freitag NE. Transcriptional regulation of prfA and its effects on Listeria monocytogenes virulence gene expression. Am Soc Microbiol General Meeting, Chicago, IL, 1999.

Shetron-Rama L, Freitag NE. Intracellular gene expression in Listeria monocytogenes: the role of PrfA DNA binding sites in regulation of transcription. Am Soc Microbiol General Meeting, Chicago, IL, 1999.

Greene SL, Freitag NE. Transcriptional regulation of prfA and its effects on Listeria monocytogenes virulence gene expression. Mid West Microbial Pathogenesis Meeting, 1999.

Shetron-Rama L, Freitag NE. Intracellular gene expression in Listeria monocytogenes: the role of PrfA and its effects on Listeria monocytogenes virulence gene expression. Mid West Microbial Pathogenesis Meeting, 1999.

Galy A, Rudraraju S, Klein J. Recovery of lymphocyte and dendritic cell subsets after autologous stem cell transplantation. Sixth Int on Workshop Langerhans Cells, New York City, NY, 1999.

Wesa A, Galy A. Immunological properties of human lymphoid-related dendritic cells generated in vitro. Sixth Int Workshop on Langerhans Cells, New York City, NY, 1999.

Gregoire L, Munkarah A, Rabah R, Lancaster WD. In vitro malignant transformation of HPV-16 E6/E7 immortalized human ovarian surface epithelial cells. Am Assoc for Cancer Res, Philadelphia, Pa, 1999.

Danjo Y, Hazlett LD, Gipson IK. Lack of ocular surface phenotype in MUC-1 null mice. Invest Ophthal Vis Sci 40:2826, 1999.

Hazlett LD, Kernacki KA. MIP-2 is a major mediator of PMN influx in ocular bacterial infection. First Intl Cong on Cytokines/Chemokines in Infect Dis, Bethesda, MD, 1999.

Hazlett LD, McClellan SA. Th1 responsiveness may dictate susceptibility to ocular challenge with Pseudomonas aeruginosa. Invest Ophthal Vis Sci 40:4178, 1999.

Kernacki KA, Barrett R, Hazlett LD. Evidence that TIMP-1 is protective against P aeruginosa induced corneal ulceration and perforation. Intl Proteolysis Society, Mackinac Island, MI, 1999.

McClellan SA, Barrett RP, Hazlett LD. Mechanisms of resistance vs susceptibility to P aeruginosa infection: The role of Langerhans cells. Invest Ophthal Vis Sci 40:1372, 1999.

Rudner XL, Kernacki KA, Hazlett LD. Early cytokine response to P aeruginosa corneal infection differs in susceptible vs resistant mice. First Int Cong on Cytokines/Chemokines in Infect Dis, Bethesda, MD, 1999.

Rudner X, Kernacki KA, Hazlett LD. Early cytokine response to P aeruginosa corneal infection idffers in susceptible vs resistant mice. Invest Ophthal Vis Sci, 40:1374, 1999.

Hobden JA, Alionte LG, Estrellas Jr PS. Pseudomonas aeruginosa staphylolytic protease and ocular virulence. Invest Opthalmol Vis Sci 40:S259, 1999.

Kernacki KA, Hobden JA, Hazlett LD. MIP-2 expression correlates with PMN influx and tissue injury during Pseudomonas aeruginosa corneal infection. Invest Opthalmol Vis Sci 40:S793, 1999.

Pillar CM, Hobden JA. The role of Pseudomonas aeruginosa alkaline protease in ocular infections. Invest Opthalmol Vis Sci 40:S259, 1999.

Pillar CM, Hazlett LD, Hobden JA. The effect of Pseudomonas aeruginosa alkaline protease on bacterial adherence in vitro. Am Soc Microbiol, p 249, 1999.

Hsia S-C, Luo H, Holland TC. Charcterization of the chromatin structure of HSV-1 promoters on episomal plasmids. Chromatin structure and function: Twenty-five years of the nucleosome. Pennsylvania State University 18th Summer Symposium Mol Biol 1:116, 1999.

Gerard HC, Rudy D, Krausse-Opatz B, Zeidler H, Kohler L, Schumacher HR, Whittum-Hudson JA, Hudson AP. Expression of C trachomatis genes required for DNA synthesis/cell division in active vs persistent infection. Arthritis Rheum 42:S384, 1999.

Gerard HC, Lu L, Schumacher HR, Clayburne G, Whittum-Hudson JA, Rank RG, Hudson AP. Time course and pathologic consequences of dissemination of Chlamydia to the joint following genital infection in a guinea pig model of reactive arthritis. Am Soc Microbiol, p 53, 1999.

Henry CH, Hughes CV, Babae R, Hudson AP, Wolford LM. Bacteria associated with reactive arthritis and the temporomandibular joint. J Oral Maxillofax Surg 57:51-52, 1999.

Henry CH, Hughes CV, Hudson AP, Wolford LM. Identification of bacteria associated with reactive arthritis in the human temporomandibular joint. Int J Oral Maxillofac Surg 28:19, 1999.

Hughes CV, Henry CH, Maizner RG, Hudson AP, Wolford LM. Mycoplasma genitalium and mycoplasma fermentans in the human temporomandibular joint. J Dental Res 78:419, 1999.

Hudson AP, Gerard HC, Wang GF, Balin BJ, Schumacher HR. Frequency of apolipoprotein E (APOE) allele types in patients with Chlamydia-induced arthritis and other arthritides. FASEB J 13:A852, 1999.

Hudson AP, Rudy D, Krausse-Opatz B, Zeidler H, Kohler L, Schumacher HR, Whittum-Hudson JA, Gerard HC. Energy metabolism of C trachomatis during active vs persistent infection. Arthritis Rheum 42:S336, 1999.

Hudson AP, Rudy D, Krausse-Opatz B, Zeidler H, Kohler L, Schumacher HR, Whittum-Hudson JA, Gerard HC. Energy metabolism of C trachomatis in active and persistent infection. Sixth Annual Midwest Microbial Pathogenesis Meeting, p 21, 1999.

Hudson AP, Wu X, Wang Z, Levin RM. Cloning and characterization of the COIV and COVIa genes from the New Zealand white rabbit. J Urol 161:49, 1999.

Wagner AD, Fresemann T, Prabst A, Schmidt WA, Gromnica-Ihle E, Hudson AP, Zeidler H. Heat shock protein 60 is present in giant cell arteritis and localizes in close vicinity to GM-CSF expression. Arthritis Rheum 42:S283, 1999.

Whittum-Hudson JA, Davis E, Vora G, Kuo P, Hudson AP, Schumacher HR, Saltzman WM, Stuart ES. Effects of the chlamydial GLXA-specific anti-idiotypic antibody vaccine on murine genital infection. Am Soc Microbiol, p 85, 1999.

Whittum-Hudson JA, Gerard HC, Davis E, Saltzman WM, Stuart ES, Schumacher HR, Hudson AP. Immunomodulation of experimental Chlamydia-associated reactive arthritis. Arthritis Rheum 42:S400, 1999.

Kuipers JG, Bunke T, Freise J, Hudson AP, Wollenhaupt J, Kohler L, Zeidler H. Sensitivitatsvergleich Chlamydia trachomatis spezifischer LCR and PCR fur die Analyse von Synovialisbiopsien. Zeitschr Rheumatol, in press.

Wan Q, Shah R, Giraldo AA, David CS, Kong YM. HLA-DQ8 transgenic class II-negative mice develop autoimmune thyroiditis after induction with human thyroglobulin. FASEB J A:1000, 1999.

Wang Q, Panos J, Yan Y, Giraldo AA, David CS, Kong YM. Characterization of H2A- E+ (AB0Ealphak) transgenic mice susceptible to foreign but not self thyroglobulin in autoimmune thyroiditis. FASEB J (in press).

Camp DM, Loeffler DA, LeWitt PA, Beaman BL. Cytotoxicity and depamine depletion in PC12 cells produced by Nocardia asteroides culture supernatants. Soc Neurosci 25:1824, 1999.

LeWitt PA, Loeffler DA, Camp DM. Purine-induced modualtion of dopamine metabolism in PC12 cells. Soc Neurosci 25:2213, 1999.

Loeffler DA, Camp DM, Mendiratta M, Yagiela H, LeWitt PA, Hyland K. Levodopa-induced alterations in regional brain concentrations of norepinephrine, serotonin and their metabolites in 6-OHDA-hemilesioned rats. Soc Neurosci 25: 1343, 1999.

Podzorski RP, Merline JR, Holsinger JH, Qureshi R. Comparison of a modified salt precipitation procedure using whole blood and lysis of isolated peripheral blood leukocytes for extraction of CMV DNA for PCR analysis. Am Soc Microbiol, 1999.

Hadas B, OSullivan NL, Montgomery PC. An in-vitro model for autoimmune dacryoadenitis: Co-culture of lacrimal gland acinar cells with lymphocytes. Int Cong Dacryology, 1999.

Montgomery PC, Skandera CA, OSullivan NL. Mononuclear cell populations in rat lacrimal glands. Invest Ophthal Vis Sci 40:S554, 1999.

OSullivan NL, Montgomery PC. Rat glandular mononuclear cell populations. Tenth Int Cong Mucosal Immunology, 1999.

Piechocki M, Ratner S. Levels of regulation of lymphocyte appendage formation and polarity. FASEB J 12:A3351, 1999.

Shuster JA, Stepaniak JA, Hu W, Sundick RS. Mutational analysis of chicken IL-2/15. FASEB J 13:A1142, 1999.

Lenz DC, Wolf NA, Smeltz RB, Swanborg RH. Attempted tolerization of DA rats with encephalitogenic peptide elicits experimental autoimmune encephalomyelitis and TH1 responses. FASEB J 13:A1124(845.13), 1999.

Smeltz RB, Wayben MHM, Wolf NA, Swanborg RH. Critical requirement for aspartic acid at position 82 myelin basic protein 73-86 for recruitment of Vbeta8.2+ T cells and encephalitogenicity in the Lewis rat. FASEB J 13:A1124 (845.12), 1999.

Smeltz RB, Wolf NA, Swanborg RH. Natural killer activity in the DA rat: Implications for autoimmunity. FASEB J 13:A1127(845.33), 1999.

Lenz DC, Wolf NA, Swanborg RH. Parental genes do not equivalently confer susceptibility to experimental autoimmune encephalomyelitis to F1 rats. FASEB J (in press).

Swanborg RH, Wolf NA. NK cells maintain immune homeostatsis. FASEB J (in press).

Ho PP, Tse HY. Fas in murine experimental autoimmune encephalomyelitis. FASEB J A1002(719.1), 1999.

Savasan S, Ozgen O, Buck , Wei W-Z, Hamre M, Weinstein H, Becton D, Ravindranath Y. Heterogeneous effect of free radical scavenging on cytarabine and daunorubicin-indeuced apoptosis in childhood AML, Blood, 1999.

Pilon S, Kelly C, Marriott E, Wei W-Z. Protection against mammary tumor growth by vaccination with recombinant human ERBB-2 DNA encoding transmembrane or cytoplasmic protein. FASEB J A:486.3, 1999.

Hudson AP, Rudy D, Krausse-Opatz B, Zeidler H, Kohler L, Schumacher HR, Whittum-Hudson JA, Gerard HC. Energy metabolism of C trachomatis in active and persistent infection. Arth Rheum 42:S336, 1999.

Jabs DA, Lee B, Whittum-Hudson JA, Prendergast RA. Th1 vs Th2 immune responses in autoimmune lacrimal gland disease in MRL/MP. Arth Rheum 42:S138, 1999.

Jabs DA, Lee B, Whittum-Hudson JA, Prendergast RA. Th1 vs Th2 immune responses in autoimmune lacrimal gland disease in MRL/MP. Invest Ophthalmol Vis Sci 40:S553, 1999.

Rorer EM, Whittum-Hudson JA, Jabs DA, Prendergast RA. Relative transcript levels of cytokines in autoimmune dacryoadenitis in MRL/MP-lpr/lpr mice. Invest Ophthalmol Vis Sci 40:S553, 1999.

Whittum-Hudson JA, Davis E, Vora G, Kuo P, Hudson A, Schumacher HR, Saltzman WM, Stuart ES. The chlamydial anti-idiotypic antibody vaccine: Tests in allogeneic mice after genital infection. Immunology Ltr 69:97, 1999.

Whittum-Hudson J, Davis E, Vora G, Kuo P, Schumacher HR, Stuart ES, Saltzman WM. Oral anti-idiotypic antibody to Chlamydial GLXA reduces genital infection and dissemination to joints. FASEB J 13:A288, 1999.

Borniva J, Song Z, Wu B, Wooley PH. T cell directed gene therapy in an experimental model of rheumatoid arthritis. Arthritis and Rheumatism, 42:S106, 1999.

Chen CY, Cavanaugh JM, Song Z, Wooley PH, Kallakuri S, Ozaktay AC, Levine RS. The effects of nucleus pulposus on lumbar nerve root structure and function. Transactions of Orthopaedic Res Soc, 1999.

Sieving A, Nasser S, Wooley PH. Macrophage responses to polymethylmethacrylate (PMMA) particles. Arthritis and Rheumatism, 42:S267, 1999.

Sieving A, Nasser S, Wooley PH. Macrophage responses to polymethylmethacrylate (PMMA) particles. Michigan Orthopaedic Soc, 1999.

Vandevorde PJ, Nasser S, Wooley PH. Antibody responses to bone soluble proteins in bone graft recipients. Michigan Orthopaedic Soc, 1999.

Vandevorde PJ, Nasser S, Wooley PH. Antibody responses to bone soluble proteins in bone graft recipients. Arthritis and Rheumatism, 42:S285, 1999.

Whalen JD, Pitil SB, Song Z, Muzzonegro T, Cha C, Wooley PH, Evans CH. Expression of the interleukin-1 receptor antagonist protein (IRAP) reduces cell death and nitric oxide production following phagocytosis of orthopaedic implant material. Transactions of Orthopaedic Res Soc, 1999.

Wooley PH, Nadim Y, Schaefer CJ, Ryan JR. The significance of the immune response in the fate of bone allografts. Transactions of the Orthopaedic Res Soc, 1999.

Yang S-Y, Song Z, Robbins PD, Evans CH, Wu B, Mayton L, Nasser S, Wooley PH. Anti-inflammatory cytokine gene therapy in a murine model of aseptic loosening. Arthritis and Rheumatism, 42:S284, 1999.