Center for Molecular Medicine and Genetics

Director: George Grunberger, MD
3216 Scott Hall
(313) 577-7323

Articles Published

Abidi F, Hall BD, Cadle RG, Feldman GL, Lubs HA, Ouzts LV, Arena JF, Stevenson RE, Schwartz CE.  X-linked mental retardation with variable somatic features (short stature, small head, small testes) linked to Xq12-q21. American Journal of Medical Genetics, 85:223-229, 1999.

Bachman NJ, Wu W, Grossman LI, Lomax MI. COX4, the gene for cytochrome  c oxidase subunit IV, and NOC4, a closely linked gene, are controlled by a bidirectional promoter. Mamm Genome, 10:506-512, 1999.

Berend SA, Feldman GL, McCaskill C, Czarnecki P, Van Dyke DL, Shaffer LG.  Investigation of two cases of paternal disomy 13 suggests timing of isochromosome formation and mechanisms leading to uniparental disomy.  American Journal of Medical Genetics, 82:275-281, 1999.

Brady TB, Kramer RL, Qureshi F, Feldman B, Kupsky WJ, Johnson MP, Evans MI.  Ontogeny of recurrent hydrocephalus:  Presentation in three fetuses in one consanguineous family.  Fetal Diagnosis and Therapy, 14:198-200, 1999.

Brooks K, Chik L, OÕBrien JE, Critchfield G, Ayoub M, Johnson MP, Evans MI.  Variability of adjustments to indecies in determining risk in biochemical screening.  Fetal Diagnosis and Therapy, 14:41-46, 1999.

Champagne N, Bertos NR, Pelletier N, Wang AH, Vezmar M, Yang Y, Heng HHQ, Yang XJ. Identification of a human histone acetyltransferase related to monocytic Luekemia zinc finger protein.  J Biol Chem, 274:28528-36, 1999.

Cheng H-L, Shy ME, Feldman EL. Regulation of insulin like growth factor binding protein 5 expression during Schwann cell differentiation. Endocrinology, 140:4478-4485, 1999.

Chiu C-H, Gregoire L, Gumucio DL, Muniz JA, Lancaster WD, Goodman M. The fetal recruitment of simian (-globin genes: insights from two New World monkeys cebus apella and callithrix jacchus (Platyrrhini, primates). M Exp Zoology, 285:27-40, 1999.

Claudio J, Liew C-C, Ma J. Heng HHQ, Stewart K, Hawley R. Cloning and expression analysis of a novel WD repeat gene, WDR3, mapping to 1p12-p13. Genomics, 59:85-89, 1999.

Devlin JW, Claire KS, Dulchavsky SA, Tyburski JG.  Impact of trauma stress ulcer prophylaxix guidelines on drug cost and frequency of major gastrointestinal bleeding.  Pharmacotherapy 19:452-460, 1999.

Di Carli MF, Bianco-Batlles D, Landa ME, Kazmers A, Groehn H, Muzik O, aGrunberger G.  Effects of autonomic neuropathy on coronary blood flow in patients with diabetes mellitus.  Circulation, 100:813-819, 1999.

Diebel LN, Liberati DM, Diglio CA, Dulchavsky SA, Brown WJ.  Synergistic effects of candida and escherichia coli on gut barrier function.  J Trauma 47:1045-1051, 1999.

Drugan A, Yaron Y, Zamir R, Ebrahim SAD, Johnson MP, Evans MI.  Differential effect of advanced maternal age on prenatal diagnosis of trisomy 13, 18, and 21.  Fetal Diagnosis and Therapy, 14:181-184, 1999.

Drugan A, Bronstein M, Itskovitz-Eldor J, Johnson MP, Evans MI.  Ontogeny of isolated ultrasound markers for fetal aneuploidy.  Fetal Diagnosis and Therapy, 14:266-269, 1999.

Dulchavsky SA, Hamilton DR, Diebel LN, Sargsyan AE, Billica RD, Williams DR.  Thoracic ultrasound idagnosis of pneumothorax.  J. Trauma 47:970-971, 1999.

Evans MI, Henry GP, Miller WA, Bui TH, Snidjers RJ, Wapner RJ, Miny P, Johnson MP, Peakman D, Johnson A, Nicolaides K, Holzgreve W, Ebrahim SAD, Babu R, Jackson L. International collaborative assessment of 146,000 prenatal karyotypes:  Expected limitations if only chromosome-specific probes and fluorescent in situ hybridization were used.  Human Reproduction, 14:1213-16, 1999.

Evans MI, Goldberg J, Horenstein J, Wapner R, Ayoub MA, Stone J, Lipitz S, Achiron R, Holzgreve W, Brambati B, Johnson A, Johnson MP, Berkowitz R.  Selective termination for structural, chromosomal, and mendelian anomalies:  International experience.  American Journal of Obstetrics and Gynecology, 181:893-897, 1999.

Feldman B, Hassan S, Kramer RL, Kasperski SB, Evans MI, Johnson MP.  Amnioinfusion in the evaluation of fetal obstructive uropathy:  The effect of antibiotic prophylaxis on complication rates. Fetal Diagnosis and Therapy, 14:172-175, 1999.

Feldman B, Yaron Y, Ayoub M, Critchfield G, Dombrowski MP, Leon J, OÕBrien JE, Evans MI.  Distribution of neural tube defects and risks as a function of maternal weight:  No apparent correlation.  Fetal Diagnosis and Therapy, 14:185-189, 1999.

Fernandez-Madrid F, VandeVord P, Yang X, Karvonen R, Simpson P, Kraut M, Granda J, Tomkiel J.  Antinuclear antibodies as potential markers in the diagnosis and  prognosis of lung cancer. Clin Cancer Res, 5:1393-400, 1999.

Ford BD, Loeb JA, Fischbach GD. Neuregulin stimulates DNA synthesis in embryonic chick heart cells. Dev Biol, 214:139-150, 1999.

Freedman AL, Smith CA, Evans MI, Gonzalez R, Johnson MP.  Long term outcome in children following antenatal intervention for obstructive uropathies. Lancet, 354:374-377, 1999.

Fusco F, Chen Q, Lamoreaux W, Figueredo-Cardenas G, Jiao Y, Coffman J, Surmeier D,  Honig M, Carlock L, Reiner A.  Cellular localization of huntingtin in striatal and cortical neurons in rats: Lack of correlation with neuronal vulnerability in HuntingtonÕs Disease.  J Neurosci, 19:1189-1202, 1999.

Garbern J, Cambi F, Shy ME, Kamholz J. The molecular pathogenesis of Pelizaeus-Merzbacher disease. Archives of Neurology, 56:1210-1214, 1999.

Garbern JY, Cambi F, Lewis R, Shy M, Sima A, Kraft G, Vallat JM, Bosch EP, Hodes ME, Dlouhy S, Raskind W, Bird T, Macklin W,  Kamholz J.  Peripheral neuropathy caused by proteolipid protein gene mutations. Annals of  New York Academy of  Science, 883:351-366, 1999.

Jani A, Menichella D, Jiang H, Chbihi T, Acsadi G, Shy ME, Kamholz J. Modulation of cell-mediated immunity prolongs adenovirus-mediated transgene expression in sciatic nerve. Human Gene Therapy, 10:787-800, 1999.

Jayaraman G, Srinivas R, Duggan C, Ferreira E, Swaminathan S, Somasundaram K, Williams J, Hauser C, Kurkinen M, Dhar R, Weitzman S, Buttice G, Thimmapaya B. p300/CBP interactions with Ets-1 and Ets-2 in the transcriptional activation of the human stromelysin promoter.  J Biol Chem, 274:17342-17352 1999.

Kannan P, Tainsky MA.  The coactivator PC4 suppresses ras-induced tansformation by rstoring AP-2 tanscriptional ativity. Mol Cell Biol, 19:899-908, 1999.

Kannan P, Yu Y,  Wankhade S, Tainsky MA. Poly ADP-ribose polymerase is a coactivator for AP-2-mediated transcriptional Activation.  Nucl Acids Res, 27:866-874, 1999.

Kosir MA, Wang W, Zukowski KL, Tromp G, Barber J. Degradation of basement membrane by prostate tumor heparanase. Surgical Research, 81:42-47, 1999.

Leach R, Ko M, Krawetz S. Assignment of amyloid-precursor-like protein 2 gene (APLP2) to 11q25 by fluorescent in situ hybridization. Cytogenetics Cell Genetics. 87:215-216, 1999.

Lewis RA, Shy ME.  Electrodiagnostic findings in CMTX: a disorder of the Schwann cell and peripheral nerve myelin.  Annals of the New York Academy of Science, 883:504-508, 1999.

Loeb JA, Khurana TS, Robbins J, Yee AG, Fischbach GD.  Expression patterns of  transmembrane and released forms of neuregulin during spinal cord and neuromuscular synapse development. Development, 126:781-791, 1999.

Marchese  A, Sawzdargo M, Nguyen T, Cheng R, Heng HHQ, Nowak T, Im D-S, Lynch K, George S, OÕDown B. Discovery of three novel orphan G-protein-coupled receptors. Genomics, 56:12-21, 1999.

Miller D, Briggs D, Brook P, Snowden H, Hamlington J, Rollinson S,  Lilford R, Krawetz SA. Evidence for a complex population of RNAs in human ejaculate spermatozoa: implications for understanding molecular aspects of spermiogenesis. Gene, 237:385-392, 1999.

Monaghan KG, Feldman GL.  The risk of cystic fibrosis in fetuses with ultrasound evidence of echogenic bowel. Prenat Diag, 19:604-609, 1999.

Olsson M, Ekblom M, Fecker L, Kurkinen M, Ekblom P.  cDNA cloning and embryonic expression of mouse nuclear pore membrane glycoprotein 210 mRNA. Kidney Int, 56:827-838. 1999.

Omori F, Messner HA, Ye J, Nell J, Gronda M, Heng HHQ.  Non-targeted integration of recombinant adeno-associated virus in human cells detected by fluorescence in situ hybridization.  Human Gene Therapy, 10:537-543, 1999.

Papponen H, Toppinen T, Baumann P, Myllylä V, Leisti J, Kuivaniemi H, Tromp G, Myllylä R.  Founder mutations and the high prevalence of myotonia congenita in northern Finland.  Neurology, 53:297-302, 1999.

Pareyson D, Menichella D, Botti S. Sghirlanzoni A, Fallica E, Mora M, Ciano C, Shy ME, Taroni F.  Heterozygous null mutation in the PO gene associated with mild Charcot-Marie-Tooth Disease. Annals of the New York Academy of Science, 883:477-481, 1999.

Park Eun-Ju, Schroen Daniel J, Yang Maozhou, Li Hui, Li Li, Chen J. Don.   SMRTe, a silencing mediator for retinoid and thyroid hormone receptors-extended isoform that is more related to the nuclear receptor corepressor  PNAS, 96:3519-3524, 1999.

Quintero RA, Johnson MP, Mendoza G, Evans MI. The ontogeny of clenched hand development in trisomy-18 fetuses: a serial transabdominal fetoscopic observation.  Fetal Diagnosis and Therapy, 14:68-70, 1999.

Saini MS, Diebel LN, Liberati DM, Albaran RG, Dulchavsky SA.  Hemorrhagic shock impairs mucosal immunity to gut-derived antigens.  Am Surg 65:637-642, 1999.

Sawzdargo M, Nguyen T, Lee D, Lynch K, Cheng R, Heng HHQ, George S, OÕDowd B. Identification and cloning of three novel human G protein-coupled receptor genes GPR52, GPR53 and GPR55 is extensively expressed in human brain.  Molecular Brain Research, 64:193-198, 1999.

Schmidt TR, Goodman M, Grossman LI. Molecular evolution of the COX7A gene family in primates. Mol Biol Evol. 16:619-626. 1999.

Stewart K, Kramer JA, Evans MI, Krawetz SA. Temporal expression of the transgenic human protamine gene cluster.  Fertility and Sterility, 71:739-745, 1999.

Stewart K, Kramer RL, Evans MI, Krawetz SA. Temporal expression of the transgenic human protameine gene cluster. Fertility and Sterility, 71:739-45, 1999.

Tsai, CH, Van Dyke DL, Feldman GL.  A child with velocardiofacial syndrome and del(4)9q34.2): another critical region associated with a velocardiofacial syndrome-like phenotype.  American J Med Genet, 82:336-339, 1999.

Vinas FC, King PK, Holdener H, Dulchavsky S, Diaz FG.  Outcome and complications of reconstruction of the thoracolumbar spine for vetbral tumors.  J Clin Neurosci 6:467-473, 1999.

Wang AH, Bertos NR, Vezmar M, Pelletier N, Crosato M, Heng HHQ, ThÕng J, Han J, Yang XJ. HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor. Molecular Cell Biology, 19:7816-27, 1999.

Wang X, Tromp G, Cole CW, Verloes A, Sakalihasan N, Kuivaniemi H.  Analysis of coding sequences for tissue inhibitor of metalloproteinases 1 (TIMP1) and 2 (TIMP2) in patients with aneurysms. Matrix Biology, 18:121-124, 1999.

X-M Tang, Beesley JS, Grinspan JB, Seth P, Kamholz J, Cambi F.  Cell cycle arrest induced by ectopic expression of p27 is not sufficient to promote oligodendrocyte differentiation.  J Cell Biochem, 76:270-279, 1999.

Xu K, Shi ZM, Veeck LL, Hughes MR, Rosenwaks Z.  First unaffected pregnancy using preimplantation genetic diagnosis for sickle cell anemia.  JAMA, 281:1701-1706, 1999.

Yaron Y, Kramer RL, Feldman B, Kasperski S, Vo T, Feldman GL, Johnson MP, Evans MI, Ebrahim SA.  Prenatal diagnosis of 46, XY/46,XX mosaicism - a case report.  Amer J Med Genet, 84:12-14, 1999.

Yaron Y, Bryant-Greenwood PK, Dave N, Moldenhauer JS, Johnson KD, Johnson MP, Evans MI.  Multifetal pregnancy reduction (MFPR) of triplets to twins:  Comparison with non-reduced triplets and twins.  American Journal of Obstetrics and Gynecology, 180:1268-71, 1999.

Yaron Y, Cherry M, OÕBrien JE, Hallak M, Johnson MP, Evans MI.  Second trimester maternal serum marker screening:  MSAFP, B-hCG, estriol, and their various combinations as predictors of pregnancy outcome. American Journal of Obstetrics and Gynecology, 181:968-974, 1999.

Yaron Y, Diamond MP, Leach R, Wykes S, BarbourSmith M, Krawetz SA.  Lysyl oxidase transcripts in peritoneal adhesions and incisional scars.  The Journal of Reproductive Medicine, 44:253-256, 1999.

Yaron Y, Hassan S, Kupferminc MJ, Geva E, Yavetz H, Evans MI.  The evaluation of fetal echogenic bowel in the second trimester.  Fetal Diagnosis and Therapy, 14:176-180, 1999.

Yoon S, Tromp G, Vongpunsawad S, Ronkainen A, Juvonen T, Kuivaniemi H. Genetic analysis of MMP3, MMP9 and PAI-1 in Finnish patients with abdominal aortic or intracranial aneurysms. Biochem Biophys Res Comm, 265:563-568, 1999.

Zachar V, Zacharova V, Fink T, Thomas RA, King BR, Ebbesen P,  Jones TB, Goustin AS. Genetic analysis reveals ongoing HIV type 1 evolution in infected human placental trophoblast.  AIDS Research and Human Retroviruses, 15:1673-1683, 1999.

Articles In Press

Ao A, Ray P, Harper J, Lesko J, Paraschos T, Atkinson G, Soussis I., Taylor D, Handyside A, Hughes MR, Winston RML.  Clinical experience with preimplantation genetic diagnosis of cystic fibrosis.  Prenatal Diagnosis  (in press)

Briscoe A.Jr, Tomkiel JE.  Chromosomal position-effects reveal different cis-acting requirements for rDNA transcription and sex chromosome pairing in Drosophila melanogaster.  Genetics (in press)

Carreno C, King M, Johnson MP Yaron Y, Diamond M, Bush D, Evans MI.  Treatment of heterotopic cervical and intrauterine pregnancy. Fetal Diagnosis and Therapy (in press)

Crawford DC, Schwartz CE, Meadows KL, Newman JL, Taft LF, Gunter C, Bailey Jr, DB, Brown WT, Carpenter NJ, Howard-Peebles P, Mazzocco MMM, Monaghan KG, Nolin SL, Reiss AL, Feldman GL, Rohlfs EM, Taylor AK, Warren ST, Sherman SL.  Survey of the fragile X syndrome CGG repeat and STR-and SNP-haplotypes in an African-American population. Amer J Hum Genet  (in press)

Cuesta IA, Moore E, Rabash R, Bawle EV. Blau Syndrome in an African American family. J Clin Rheumotol. (in press)

Drugan A, Johnson MP, Evans MI.  Ultrasound screening for fetal chromosome anomalies.  American Journal of Medical Genetics (in press)

Evans MI.  Genetic Counseling, Screening, Diagnosis, and Fetal Therapy.  Phillipine Journal of Obstetrics and Gynecology  (in press)

Feldman B, Ebrahim SAD, Gyi K, Flore LA, Evans MI.  Rapid confirmation of previously detected prenatal mosaicism by fluorescence in situ hybridization in interphase uncultured amniocytes.  Genetic Testing (in press) and intrauterine pregnancy.   Fetal Diagnosis and Therapy (in press)

Feldman B, Ebrahim SAD, Hazan SL, Gyi K, Johnson MP, Johnson A, Evans MI.  Routine prenatal diagnosis of aneuploidy by FISH studies in high risk pregnancies.  American Journal of Medical Genetics (in press)

Feldman GL, Schuffenecker I, Lenoir G, Saxe AW, Jackson CE.  Variable expressivity of Familial Medullary Thyroid Carcinoma (FMTC) due to a RET codon 804 (GTG(ATG) mutation in two families: reluctance of gene carriers to accept prophylactic thyroidectomy. Surgery. (in press)

Haddad B, Subramanian S, Chong S, Hughes MR.  Molecular genotyping of single cells.  Human Molecular Reproduction  (in press)

Jean-Guillaume D, Awatramani R, Lee A., Mason LM, Lintner RN, Kendler A, Kamholz J, Raine CS, Dyer CA. GFAP-positive non-myelinating ligodendrocytes in normal and pathologic adult brain. J. Neurosci Res. (in press)

Krajewski K, Lewis R, Fuerst D, Turansky C, Hinderer S, Garbern J, Kamholz, J, Shy ME.  Neurological dysfunction and axonal degeneration in CMT 1A, Brain (in press)

Lewis RA, Shy ME, Sumner AJ. Electrophysiologic features of inherited demyelinating neuropathies: a reappraisal.  Muscle and Nerve (in press)

Miller OJ, Miller DA.  Chromosomes.  McGraw-Hill Encylcopedia of Science and Technology. (in press)

Miller V, Ransom SB, Ayoub MA, Krivchenia EL, Evans MI.  The fiscal impact of a potential legislative ban on second trimester for prenatally diagnosed abnormalities.  American Journal of Medical Genetics (in press)

Miller VL, Ransom SB, Shalhoub A, Sokol RJ, Evans MI.  Multifetal pregnancy reduction:  perinatal and fiscal outcomes.  American Journal of Obstetrics and Gynecology (in press)

Monaghan, KG, Jackson CE, KuKuruga DL, Feldman GL.  Mutation analysis of the cystic fibrosis and cationic trypsinogen genes in patients with alcohol-related pancreatitis. American Journal of Medical Genetics (in press)

Oh S Paul, Seki Tsugio, Goss KA, Takeshi I, Yi Y, Donahoe PK, Li L, Dijke PT, Miyazono K, Kim S, Li E. ALK-1 modulates TGF-beta 1 signalings during vascular development. PNAS (in press)

Pryde P, Hallak M, Lauria M, Littman L, Bottoms S, Johnson M, Evans MI.  Severe oligohydramnios with intact membranes: an indication for diagnostic amnioinfusion.  Fetal Diagnosis and Therapy (in press)

Qureshi F, Jacques SM, Feldman B, Doss BJ, Johnson A, Evans MI, Johnson MP.  Fetal obstructive uropathy in trisomy syndromes.  Fetal Diagnosis and Therapy (in press)

Rabah R, Sakr W, Thomas R, Lancaster WD, Gregoire L. Human papillomavirus type, proliferative activity and P53: potential markers of aggressive papillomatosis. Arch Pathol Lab Med (in press)

Rabah R, Lancaster WD, Thomas R, Gregoire L. HPV-11 associated recurrent respiratory papillomatosis is more aggressive than HPV-6 associated disease. Ped. Develop. Pathol. (in press)

Ransom SB, Mickelson IH, Makela PR, Essenmacher L, Evans MI.  The quality of cost-effectiveness and cost-benefit analyses in the obstetrics and gynecology literature.  American Journal of Obstetrics and Gynecology (in press)

Seubert DE, Feldman B, Krivchenia EL, Evans MI, Barki J, Johnson MP.  Molecular and fetal tissue biopsy capabilities are needed to maximize prenatal diangosis of junctional epidermolysis bullosa (JEB):  Fetal skin biopsy using a 2mm microendoscope.  Fetal Diagnosis and Therapy (in press)

Shy ME, Kamholz J.  Hereditary Neuropathies.  Neurobase (in press)

Shy ME. Axonal loss in inherited demyelinating neuropathies: Lessons from PMP-22 mutant mice.  Neurology Network Commentary  (in press)

Sohn RL, Murray MT, Nyitray J, Purray P, Franko AP, Palmer K, Diebel LN, Hwang P, Dulchavsky SA.  Biolistic delivery of epidermal growth factor mRNA corrects steroid impaired wound healing.  J Molec Med (in press)

Wykes SM, Miller D, Krawetz SA. Mammalian spermatozoal mRNAs: Tools for functional analysis of male gametes.  Journal of Submicroscopic Cytology and Pathology (in press)

Xu W, Manichella D, Jiang H, Vallat J-M, Lilien J, Kamholz J, Shy ME. P0 is involved in the regulation of myelin gene expression and myelin morphogenesis. Journal of Neuroscience Research (in press)

Yaron Y, Rotter V, Aloni R, Schwartz D, Evans MI.  Expression of the p53 tumor suppressor gene in the mouse ovary during an artificially induced ovulatory cycle.  Journal of Reproductive Medicine (in press)

Books, Chapters and Reviews

Bui TH, Jaffe R, Lindholm H, Evans MI.  Fetal spine defects.  In, Jaffe R, Bui TH (eds).  Obstetric Ultrasonography:   A Clinical Guide, Parthenon Publishing, London.  pp.199-216, 1999.

Buttino L Jr., Evans MI, Sibai BM (eds).  Study Guide for Principles and Practices of Medical Therapy in Pregnancy-3rd Edition.  Appleton and Lange Publishing Co., Norwalk, Connecticut, 1999.

Drugan A, Feldman B, Johnson MP, Evans MI.  Prenatal Diagnosis:  Procedures and trends. In, Avery GB, MacDonald M, Fletcher MA (eds).  Neonatology:  Pathophysiology and management of the newborn, 5th Edition.  Lippincott Williams & Wilkins, Philadelphia pp.  161-171, 1999.

Dulchavsky SA, Schwartz SI.  Alexander J. Walt Memoirs.  Wayne State University Press.  Detroit, 1999.

Evans MI, Yaron Y, Lewis P, Hume RF.  Fetal Pharmacologic Therapy.  In, Kurjak A, Nicolaides K, et al (eds).  Textbook of Perinatal Medicine.  Parthenon Publishing, London, pp. 1065-1072, 1999.

Evans MI, Johnson MP.  Multifetal pregnancy reduction.  In, Reece EA, Hobbins J (eds).  Medicine of the Fetus and Mother. 2nd Edition, Lippincott/Raven, Philadelphia, pp. 1433-1438, 1999.

Evans MI.  Overview of Fetal Therapy.  In:  New M (ed).  Diagnosis and Treatment of the Unborn Child, Idelson-Gnocchi, Ltd. Reddick, FL, pp.133-136, 1999. 

Evans MI.  Techniques for Hematopoietic Stem Cell Transfer.  In:  New M (ed).  Diagnosis and Treatment of the Unborn Child, Idelson-Gnocchi, Ltd. Reddick, FL, pp.137-139, 1999.

Evans MI, OÕBrien JE, Johnson A.  Screening for Aneuploidy.  In, (eds).  Current Opinion in Obstetrics and Gynecology 1/2.  Lippincott, Williams & Wilkins, London, pp 115-118, 1999.

Evans MI, Yaron Y, Littmann L, Tapin C, Belkin HR.  Issues in multifetal pregnancy reduction.  In, Chervenak F, Kurjak A (eds).  Fetal Medicine:  The Clinical Care of the Fetus as a Patient.  Parthenon Publishing, London, pp 136-150, 1999.

Evans MI, Flake AW, Johnson MP, Belkin HR, Johnson A, Harrison M.  In utero treatment:  state of the art.  In, Chervenak F, Kurjak A (eds).  Fetal Medicine:  The Clinical Care of the Fetus as a Patient,  Parthenon Publishing, London. pp. 186-204, 1999.

Evans MI, Evans WJ, Johnson MP.  Ethics of Reproduction.  In, Tierney H (ed).  WomenÕs Studies Encyclopedia.  Greenwood Publishing Co, Westport, CT. pp. 1206-1221, 1999.

Evans MI, OÕBrien JE, Dvorin E, Critchfield G.  Screening for aneuploidy.  In, Queenan JJ (ed).  Management of High Risk Pregnancy, 4th Edition  Blackwell Science, Massachusetts, pp 119-135, 1999.

Evans MI, Hume RF, Yaron Y, Kramer RL, Johnson MP.  Reduction of high multiple pregnancies.  In, Neilson B, Ballieres JP (eds).  Clinical Obstetrics and Gynecology , J. B. Lippincott, Philadelphia, PA. pp. 147-159, 1999.

Evans MI, Harrison M, Johnson MP, Feldman B, Holzgreve W.  Fetal Therapy.   In, Avery Gb, MacDonald M, Fletcher MA (eds).  Neonatology:  Pathophysiology and management of the newborn, 5th Edition.  Lippincott Williams & Wilkins, Philadelphia pp. 173-185, 1999.

Evans MI, Johnson MP.  Multifetal pregnancy reduction and selective termination.  In, James DK, Star PJ, Weiner CP, Gonik B (eds).   High Risk Pregnancy:  Management Options.  WB Saunders, London, England. pp. 243-248, 1999.

Evans MI, King M, Hoffman E, Holzgreve W.  Fetal Tissue Biopsies.   In, James DK, Star PJ, Weiner CP, Gonik B (eds).  High Risk Pregnancy:  Management Options.  WB Saunders, London, England. pp. 235-241, 1999.

Evans MI, Johnson MP.  Genetics and Prenatal Diagnosis.  In, Dombrowski MP, Ransom SB, McNeeley SG, Diamond MP, Munkarah AR (eds)  Practical Strategies in Obstetrics and Gynecology, W. B. Saunders Publishing Co., Philadelphia, PA, pp 213-223, 1999.

Evans MI, Yaron Y, Kramer RL, Johnson MP.  Options following the diagnosis of a fetal anomaly.  In, McCormick MC (ed).  Prenatal Care:  Effectiveness and Implementation, Cambridge University Press, Cambridge, England, pp 244-258, 1999.

Evans MI.  Editorial.  Current Opinion in Obstetrics and Gynecology 11:13-14, 1999.

Evans MI, Screening for aneuploidy.  Current Opinion in Obstetrics and Gynecology 11(2):115-18, 1999.

Evans MI, Johnson A, Gilbert AD.  The future of chromosome screening: ultrasound, biochemistry, or both.  Frontiers in Fetal Health: A Global Perspective 1(1):16, 1999.

Fernandez-Madrid F and Tomkiel J.  ÒAntinuclear Antibodies and Lung CancerÓ in  Autoimmunity and Cancer, Ed. Y. Schoenfeld.  Springer-Verlag, Berlin. 1999.

Garbern J, Lewis R, Bosch EP, Sima A, Shy M, Menichella D, Vallat J-M, Cambi F, and Kamholz J.  Peripheral neuropathy caused by mutations of the proteolipid protein gene. In: Charcot-Marie-Tooth disorders. Shy M. and Kamholz J. eds.  Annals of the New York Academy of Science 883: 351-365, 1999.

Grunberger G.  Diagnosis and evaluation of the diabetic patient with erectile dysfunction.  Current Concepts in the Management of Erectile Dysfunction 1: 2-3, 1999.

Isada NB, Martin LS, Evans MI.  Prenatal diagnosis in the molecular age.  In, Avery GB, MacDonald M, Fletcher MA (eds).  Neonatology:  Pathophysiology and management of the newborn, 5th Edition.  Lippincott Williams & Wilkins, Philadelphia. pp. 111-123, 1999.

Jani A, Menichella D, Jiang H, Acsadi G, Kamholz J, and Shy ME. Overcoming cellular immunity to prolong adenoviral mediated gene expression in sciatic nerve. In: Charcot-Marie-Tooth disorders. Shy M. and Kamholz J. eds. Annals of the New York Academy of Science 883: 397-414, 1999.

Kamholz J, Awatramani R, Menichella D, Jiang H. Xu W, and Shy ME. Regulation of myelin-specific gene expression: relevance to CMT1. In: Charcot-Marie-Tooth disorders. Shy M. and Kamholz J. eds.   Annals of the New York Academy of Science 883: 91-109, 1999.

Krajewski K, Turansky C, Lewis R, Garbern J, Hinderer S, Kamholz J, and Shy ME. Correlation between weakness and axonal loss in patients with CMT1A. In: Charcot-Marie-Tooth disorders. Shy M. and Kamholz J. eds. Annals of the New York Academy of Science 883: 490-492, 1999.

Krawetz SA, Kramer JA and McCarrey JR. Reprogramming the male gamete genome: a window to successful gene therapy.  Gene 234:1-9, 1999.

Menichella DM, XuW, Jiang H, Sohi J, Vallat JM, Baron P, Kamholz J, and Shy ME. The absence of myelin P0 protein produces a novel molecular phenotype in Schwann cells. In:  Charcot-Marie-Tooth disorders. Shy M. and Kamholz J. eds. Annals of the New York Academy of Science 883: 281-294, 1999.

Murray MT and Reinbold R. ÒIsolation and characterization of maternal mRNPs from Xenopus oocytesÓ in A Comparative Methods Approach to the Study of Oocytes and Embryos. Ed. Richter J, Oxford University Press, p. 227-240, 1999.

Rodeck CH, Whittle MJ, Ferguson M, Hanson M, Bewley S, Nelson R, Holzgreve W, Evans MI, Benacerraf B, Trudinger B, Chiswick M (eds).  Fetal Medicine:  Basic Science and Clinical Practice.  Churchill Livingstone, London, England, 1999

Chapter 62  Lewis P, Yaron Y, Evans MI.  Diagnosis and treatment of fetal endocrine disorders, pp 829-834

Chapter 44  Evans MI, Krivchenia EL, King M, Hoffman E.  Muscular dystrophy, pp. 519-524

Chapter 66 Dommergues M, Aubry MC, Mahieu-Ceputo D, Evans MI, Dumez Y. Multifetal pregnancy reduction and selective termination, pp 879-886.

Shy ME, Kamholz J, and Lovelace RE, eds. Charcot-Marie-Tooth disorders. Annals of the New York Academy of Science, Volume 883, 1999.

Shy ME, Kamholz J, and Lovelace RE. Introduction to the 3rd International Conference on Charcot-Marie-Tooth disorders. In:  Charcot-Marie-Tooth disorders. Shy ME and Kamholz J. eds. Annals of the New York Academy of Science 883: xiii-xviii, 1999.

Yaron Y, Evans MI. Fetal metabolic and gene therapy.  In, Reece EA, Hobbins J (eds).  Medicine of the Fetus and Mother. 2nd Edition, Lippincott/Raven, Philadelphia, pp. 873-890, 1999.

Yaron Y, Flake AW, Johnson MP, Evans MI. Fetal stem cell and gene therapy.  In, Kurjak A, Nicolaides K, et al (eds).  Textbook of Perinatal Medicine.  Parthenon Publishing, London,  pp. 1093-1103, 1999.

Books and Chapters in Press

Evans MI, Rodeck CH (eds).  Ultrasound and Fetal Therapy.  Parthenon Publishing Co., London, England, (in press).

Chapter 1 Johnson MP, Feldman B, Evans MI.  Fetal shunt procedures, pp. 1-18

Chapter 8 Evans MI, Hume RF, Lewis P, Feldman B, Yaron Y.  Pharmacologic fetal therapy, pp 95-104.

Chapter 9  Yaron Y, Flake AQ, Zanjani E, Johnson MP, Evans MI. Stem Cell Fetal Therapy, pp 105-112. Evans MI, (ed). Prenatal Diagnosis:    Genetics, Reproductive Risks, Testing, and Managment.  Appleton and Lange Publishing Co., Norwalk, Connecticut, (in press).

Chapter 35  Evans MI, Rodeck CH, Holzgreve W, et al.  CVS

Chapter 37  Evans MI, et al.  Tissue biopsies

Chapter 42  Evans MI, et al.  Biochemical screening

Chapter 54  Evans MI, Rodeck CH, et al.  Selective termination

Evans MI, Platt LD, de la Cruz F (eds).  Fetal Therapy.  Parthenon Publishing Company, London

Chapter     Evans MI.  Metabolic therapy, (in press).

Evans MI, Ginsburg KA (eds).  Pretest:  Obstetrics and Gynecology, 9th Edition.  McGraw-Hill, New York, (in press).

Evans MI, et al. Fetal Therapy and Fetal Surgery.  In, Gabbe SG, Niebyl JR, Simpson JL (eds.) Obstetrics:  Normal and Problem Pregnancies, 4th Edition, W. B. Saunders, New York, (in press).

Evans MI, et al.  Fetal muscle biopsy.  In, Quintero RA (ed).  Diagnostic and Operative Fetoscopy, Parthenon Publishing Co., New York, (in press).

Evans MI and Levy, H. The future of newborn screening belongs to obstetricians.  In, Simonsen & B. Norgaard-Pedersen (ed).  Neonatal screening in the next millenium.  Proceedings of the 4th meeting of the international society for neonatal screening.  Scandinavian University Press, Oslo, (in press).

Evans MI, Dvorin E, Bui TH, OÕBrien JE. Biochemical screening for aneuploidy.  In:  Sciarra J (ed).  Gynecology and Obstetrics.  Lippincott Raven Publishing Co., Philadelphia, (in press).

Harrison MR, Evans MI, Adzick NS, Holzgreve W (eds).  The Unborn Patient:  The Art and Science of Fetal Therapy, 3rd Edition.  W.B. Saunders Publishing Company, Philadelphia, (in press).

Holzgreve W, Tercanli S, Evans MI, Miny P. Placental biopsies for rapid karyotyping in the second and third trimesters (late CVS) in high risk pregnancies. In, Antsaklis AJ (ed),  Prenatal Diagnosis and Fetal Treatment, (Greek), (in press).

Johnson MP, et al.  Lower urinary tract assessment. In, Quintero RA (ed).  Diagnostic and Operative Fetoscopy, Parthenon Publishing Co., New York, (in press).

Kuivaniemi H and Tromp G. Search for the aneurysm susceptibility gene(s). In: Development of Aneurysms. Richard Keen and Philip Dobrin, editors, Landes Bioscience, Georgetown, Texas, (in press).

Miller OJ and Therman E.  Human Chromosomes, 4th Edition. Springer-Verlag, New York, (in press).

Ransom  SB, Dombrowski MP, Evans MI (eds).  Contemporary Therapy in Obstetrics and Gynecology.  W. B. Saunders Publishing Company, Philadelphia, (in press).

Shy ME. Inherited Neuropathies, in Peripheral Neuropathy Syllabus, for annual American Academy of Neurology course on Peripheral Neuropathies, (in press).

Shy ME and Lewis RA. Inherited Neuropathies. Neuroscular Diseases. Buttermworth-Heinemann, (in press).

Victorina WM and G Grunberger: Thiazolidinediones: Finally treating the disease. Practical Diabetology, (in press).

Wykes SM. and  Krawetz SA, Gene Potentiation: Forming long-range open chromatin structures. Gene Therapy and Molecular Biology, (in press).

Abstracts Published

Bawle EV, Moestrup SK. Normal size cubilin in a patient with megaloblastic anemia. Am J Hum Genet Suppl 65:A231, 1999.

Boucher S, Carlock L, Skoff R. PLP regulates survival and death of neurons. Great Lakes Glia Meeting, Thompsonville, MI 1999. 

Cambi F, Garbern J, Shy M, Kamholz J.  X-linked spasticity syndromes caused by mutations in the PLP gene. J Neurochem, 72,:S17, 1999.

Carreno CA, Yaron Y, Feldman B, Treadwell M, Johnson MP, Ayoub MA, Evans MI.  First trimester embryo size discordancy: A predictor of prematurity following multifetal pregnancy reduction (MFPR). Society for Maternal Fetal Medicine Annual Meeting. San Francisco, CA, January 18-23, 1999. American Journal of Obstetrics and Gynecology  180:S104, 1999.

Chik L, Spencer K, OÕBrien JE, Sokol R, Macri J, Pandian R, Evans MI.  Disparities in risk estimates for Down syndrome (DS) in biochemical screening:  A comparison of methods on decision cut-points.  Society for Gynecologic Investigation, 46th Annual Meeting. Atlanta, GA, March 10-13, 1999.  Journal of the Society for Gynecologic Investigation, 6:99A, 1999.

Cypher M, Perry C, Nguyen M, Skoff R, Carlock L.  Protein processing and cell death in transfected and stable cell lines expressing normal or mutant PLP/DM20 proteins. 30th Annual Meeting, New Orleans, LA 1999

Cypher MA, Perry C, Nguyen M, Skoff R, Carlock L.  Comparison of normal and mutant PLP/DM20 protein transport with cell death in transfected and stable cell lines expressing normal or mutant PLP/DM20-EGFP fusion proteins. European Soc. for Dysmyelinating Diseases. (Padua, Italy) 1999.

Cypher MA, Kerwin S, Perry C, Skoff R, Carlock L.  Examining transport and processing of normal and mutant PLP/DM20 proteins in stable cell lines.  Great Lakes Glia Meeting, Thompsonville, MI, 1999.

de la Cruz F, Shifrin H, Elias S, Bianchi DW, Jackson L, Evans MI, Simpson JL, Holzgreve W, Klinger K.  Low false positive rates of aneuploidy detection using fetal cells isolated from maternal blood.  Fetal Diagnosis and Therapy, 13(6):380, 1999.

Decker AB, Coccia CT, Feldman GL.  First report of two siblings with apparently isolated odontohypophosphatasia: Dominant or recessive inheritance.  Amer J of Hum Genet, 65:A146.  1999.

Diebel LN, Liberati DM, Diglio CA, Saini MS, Dulchavsky SA. Alcohol effect on intestinal barrier function and inflammatory cytokine production.  The Western Trauma Association, 29th Annual Scientific Meeting, Crested Butte, CO. February 28-March 6, 1999.

Drugan A, Avrahami R, Zamir R, Itskovitz-Eldor J, Sokol RJ, Evans MI.  Fetal gender impact on incidence and implications of sonographic markers for Down syndrome (SMDS).  Society for Maternal Fetal Medicine Annual Meeting. San Francisco, CA, January 18-23, 1999.  American Journal of Obstetrics and Gynecology,  180:S172, 1999.

Drugan A, Feldman B, Ebrahim SAD, Johnson MP, Krivchenia EL, Kasperski S, Evans MI.  Differential impact of age, ultrasound, and biochemical screening on aneuploid detection. Society for Gynecologic Investigation, 46th Annual Meeting. Atlanta, GA, March 10-13, 1999.  Journal of the Society for Gynecologic Investigation,  6:99A, 1999.

Evans MI, Wapner R, Carpenter R, Goldberg J, Timor-Tritsch IE, Ayoub MA, Stone J, Horenstein J, Snijders R, Dommergues M, Brambati B, Nicolaides K, Holzgreve W, Tuliu L, Lerner J, Dumez Y, Monteagudo A, Johnson MP, Berkowitz R.  International collaboration on multifetal pregnancy reduction (MFPR):  Dramatically improved outcomes with increased experience.  Society for Maternal Fetal Medicine Annual Meeting. San Francisco, CA, January 18-23, 1999.  American Journal of Obstetrics and Gynecology,  180:S28, 1999.

Evans MI, Goldberg J, Horenstein J, Wapner R, Ayoub MA, Stone J, Lipitz S, Achiron R, Holzgreve W, Brambati B, Johnson A, Johnson MP, Berkowitz R.  Selective termination (ST) for structural (STR), chromosomal CHR), and Mendelian (MEN) anomalies:  International experience.  Society for Maternal Fetal Medicine Annual Meeting. San Francisco, CA, January 18-23, 1999.  American Journal of Obstetrics and Gynecology, 180:S31, 1999.

Evans MI, Nicolaides K, Goldberg JD, Wapner RJ, Horenstein J, Dommergues M, Holzgreve W, Timor-Tritsch I, Carpenter R, Baker C, Ayoub M, Shaloub A, Brambati B, Snijders R, Monteagudo A, Berkowitz R.   Birth weight discordancy among remaining fetuses after multifetal pregnacy reduction (MFPR) and selective termination :  Correlation with starting number. Society for Gynecologic Investigation, 46th Annual Meeting. Atlanta, GA, March 10-13, 1999.  Journal of the Society for Gynecologic Investigation,  6:5A, 1999.

Evans MI, Wapner RJ, Timor-Tritsch I, Carpenter R, Goldberg JD, Nicolaides K, Dommergues M, Dumez Y, Horenstein J, Stone J, Ayoub M, Shalhoub A, Baker C, Monteagudo A, Snijders R, Berkowitz R.  Methods of initiation of multifetal pregnancies:  Implications for outcomes following multifetal pregnancy reduction.  Society for Gynecologic Investigation, 46th Annual Meeting. Atlanta, GA, March 10-13, 1999.  Journal of the Society for Gynecologic Investigation,  6:213A, 1999.

Evans MI, Carpenter R, Goldberg JD, Johnson A, Nicolaides K, Holzgreve W, Berkowitz RL, Timor-Tritsch I, Wapner RJ. Collaborative multifetal pregnancy outcomes (MFPR):  outcomes and fetal growth.  International Fetal Medicine and Surgery Society.  Carlisle Cumbria, UK, May 19-23, 1999.

Evans MI, Goldberg J, Ayoub MA, Liptz S, Johnson A, Berkowitz R.  Second trimester selective termination update. International Fetal Medicine and Surgery Society.  Carlisle Cumbria, UK, May 19-23, 1999.

Feldman B, Hazan SL, Ebrahim SAD, Krivchenia EL, Johnson MP, Evans MI.  Pseudomosaicism from maternal cell contamination is much more prevelent with cytogenetically abnormal fetuses.  Society for Maternal Fetal Medicine Annual Meeting. San Francisco, CA, January 18-23, 1999.  American Journal of Obstetrics and Gynecology, 180:S56, 1999.

Feldman B, Hazan SL, Ebrahim SAD, Krivchenia EL, Drugan A, Johnson MP, Evans MI.  Pregnancy outcomes of confined placental mosaicism Ð a 10 year study.  Society for Maternal Fetal Medicine Annual Meeting. San Francisco, CA, January 18-23, 1999.  American Journal of Obstetrics and Gynecology, 180:S56, 1999.

Feldman B, Ebrahim SAD, Gyi K, Ayoub MA, Johnson MP, Dombrowski MP, Evans MI.  Utilization of fluorescent in situ hybridization for diagnosis of abnormal fetal karyotypes other than aneuploidy.  Society for Maternal Fetal Medicine Annual Meeting. San Francisco, CA, January 18-23, 1999.  American Journal of Obstetrics and Gynecology, 180:S57, 1999.

Feldman B, Ebrahim SAD, Gyi K, Johnson A, Johnson MP, Evans MI.  Routine prenatal diagnosis of aneuploidy by FISH studies in high risk pregnancies.  International Fetal Medicine and Surgery Society.  Carlisle Cumbria, UK, May 19-23, 1999.

Feldman GL, Schuffenecker I, Lenoir GM, Saxe AW, Roberson JR, Petrucelli N, Jackson CE.  Variable expressivity of Familial Medullary Thyroid Carcinoma (FMTC) due to a RET V804M (GTG(ATG) mutation in two families: reluctance of gene carriers to accept prophylactic thyroidectomy.  Genet in Med, 1:45.  1999.

Finley Jr RL, Zhong J. Towards a Drosophila genome-wide protein interaction map. Abstract. 40th Annual Drosophila Research Conference, Seattle, WA March 1999.

Fitzgerald J, Anderson R, Funnell M, Gruppen L, Grunberger G, Jacober S, Aman L. Perceptions and attitudes in type 2 diabetes by treatment and ethnicity. Diabetes 48; Supp 1: A324, 1999.

Flack JM, Staffileno BA, Hamaty M, Kuivaniemi H, Tromp G, Dudley A, Grimm RH.  Angiotensin converting enzyme gene polymorphism influences blood pressure response to dietary sodium in normotensive African-Americans. Circulation, 99:1110, 1999.

Garbern JY, Heng HHQ, Wu R-P, Ye CJ, Awatraman R, Kamholz J. The human GTX gene maps to 10q26, a region often deleted in gliomas. in American Society for Human Genetics, 65, Program Nr: 1022, 1999.

Gregoire L, Munkarah A, Rabah R, Lancaster WD.  In vitro malignant transformation of HPV-16 E6/E7 immortalized human ovarian surface epithelial cells. American Association for Cancer Research, Philadelphia, PA. 1999.

Grossman LI, Wu W, Schmidt TR, Goodman M. Novel evolutionary interaction of cytochrome c and cytochrome c oxidase in higher primates. Gordon Research Conference on Bioenergetics, Proctor Academy, Andover, NH, June 27-July 2, 1999.

Grossman LI, Wu W, Schmidt TR, Goodman M. Novel evolutionary interaction of cytochrome c and cytochrome c oxidase in higher primates. 4th European Meeting on Mitochondrial Pathology, Cambridge, September 16-19, 1999.

Grunberger G, WM Weston, R Patwardhan, and EB Rappaport: Rosiglitazone once or twice daily improves glycemic control in patients with type 2 diabetes.  Diabetologia 42, Suppl 1: A4, 1999.

Grunberger G, WM Weston, R Patwardhan, and EB Rappaport: Rosiglitazone once or twice daily improves glycemic control in patients with type 2 diabetes. Diabetes 48; Suppl 1: A102 1999.

Hao H-N, Thomas RA, Zhao J, Abdel-Haq N, Lyman WD.  HIV passaged through microglia changes its chemokine receptor specificity.  A P8-2, Am Soc for Virology 18th Ann Meeting, Univ of Massachusetts, July 10-14, 1999.

Hao H-N, Thomas RA, Abdel-Haq N, Zhao J, Lotoczky WE, Grever WE, Lyman WD. Enhancement of Neuronal Toxicity by Exogeneous HIV-1 tat in Mixed Astrocyte/Neuronal Cultures. A 906.15, Soc for Neurosci 29th Ann Meeting, Miami Beach, October 23-28, 1999.

Heng H, Krawetz SA, Liu G, Bremer S, Moens P, Spyropoulos B.  Novel Features of chromatin loop structure and its formation. Center for Molecular Medicine & Genetics Wayne State University Scientific Retreat Maumee Bay, 1999.

HŸttemann M, MŸhlenbein, Schmidt TR, Grossman LI, Kadenback B. Defective splicing of the subunit VIIaL gene of cytochrome c oxidase in a patient with Leigh syndrome. 4th European Meeting on Mitochondria Pathology, Cambridge, September 16-19, 1999.

Johnson A, Leach R, Johnson MP, Lee H, Qureshi F, Hassan S, Romero R, Evans MI.  Selective termination using bipolar cautery: the Detroit experience.  International Fetal Medicine and Surgery Society.  Carlisle Cumbria, UK, May 19-23, 1999.

Johnson A, Leach R, Lee HM, Richter R, Qureshi F, Jacques SM, Romero R, Hassan S, Sokol RJ, Evans MI.  Bipolar Coagulation (BPF): An Improved Method of Selective Termination in Complicated Monochorionic Twin Pregnancies.  Central Association of Obstetricians and Gynecologists. 1999 Annual Meeting, Maui, HI, October 25-30, 1999.

Johnson MP, Feldman B, Kasperski S, Qureshi F, Jacques S, Gonzalez R, Evans MI.  Prenatal evaluation and shunting for fetal obstructive uropathy: Management of nearly 100 cases.  Society for Maternal Fetal Medicine Annual Meeting.  San Francisco, CA, January 18-23, 1999.  American Journal of Obstetrics and Gynecology, 180:S30, 1999.

Johnson MP, Romero R, Edwin SS, Feldman B, Kasperski S, Qureshi F, Evans MI.  Evidence for differential expression of growth factors and cytokinse in the urine of fetuses with obstructive uropathy.  Society for Maternal Fetal Medicine Annual Meeting.  San Francisco, CA, January 18-23, 1999.  American Journal of Obstetrics and Gynecology, 180:S11, 1999.

Khan O, Tselis A, Garbern J, Kamholz J, Lisak R. Clinical profile of relapsing multiple sclerosis in African Americans: Impact of immunomodulating therapy on disease course. Ann Neurol, 46, 471, 1999.

Kolonin MG, Finley Jr RL. Analysis of cyclin J function with peptide aptamers. Abstract. 40th Annual Drosophila Research Conference, Seattle, WA March 1999.

Krajewski K, Shein N, Watson C, Fuerst D, Kamholz J, Garbern J, Shah J, Shah A, Chugani HT.  The genetics of hippocampal sclerosis. Epilepsia 40, 234, 1999.

Kramer RL, Comeaux Ty, Kowalczyk CL, Yaron Y, Feldman B, Johnson MP, Evans MI. Ovulation induction influences maternal serum markers for Down syndrome and neural tube defects.  Society for Maternal Fetal Medicine Annual Meeting.  San Francisco, CA, January 18-23, 1999. American Journal of Obstetrics and Gynecology, 180:S56, 1999.

Kramer JA, McCarrey JM, Djakiew D, Krawetz SA.  Selective gene potentiation during mammalian spermatogenesis. Great Lakes Mammalian Development Meeting 1999, Toronto, Ontario, Canada, 1999.

Kramer RL, OÕBrien JE, Dombrowski MP, Drugan A, Feldman B, Ayoub MA, Evans MI.  Insufficient power to verify the accuracy of risk predictions in biochemical screening even in the worldÕs largest databases.  Society for Gynecologic Investigation, 46th Annual Meeting. Atlanta, GA, March 10-13, 1999.  Journal of the Society for Gynecologic Investigation, 6:99A, 1999.

Krawetz SA. Reprogramming a segment of chromosome 16 for male gamete expression and fertilization. ÒGene Therapy and Molecular Biology International ConferenceÓ Crete, Greece, 268-271, 1999.

Kuivaniemi H, Yoon S, Thatai D, Marsh J,  Malcom GT, Strong JP, McMahan CA, Tromp G.  Plasminogen activator inhibitor-1 is not associated with the amount of fibrous plaque in arteries, but contributes to increased risk of heart attack. Circulation, 99:1116, 1999.

Lewis D, Bischoff, Simpson JL, Elias S, Bianchi D, Klinger K, Dukes K, Sullivan L, Evans M, Holzgreve W, Hahn S, Jackson L, Wapner R, de la Cruz F, Shifrin H.  Multicenter study of fetal cell recovery from maternal circulation and analysis.  49th Annual Meeting of the American Society of Human Genetics, San Francisco, CA October 10-23, 1999.

Martins RP, Krawetz SA. Characterization of the human lysyl oxidase locus: a model to study the mechanism of gene potentiation. Center for Molecular Medicine & Genetics, Wayne State University, Scientific Retreat Maumee Bay B-6, 1999.

Mathews ST, Srinivas PR, Grunberger G, Goustin AS.  Role of MAP kinase signaling pathways in RSK2 activation in vascular smooth muscle cells.  FASEB J 13:A1489, 1999.

Miller V, Ransom SB, Ayoub MA, Krivchenia EL, Evans MI.  The fiscal impact of a potential legislative ban on second trimester medically indicated abortions.  Society for Maternal Fetal Medicine Annual Meeting. San Francisco, CA, January 18-23, 1999.  American Journal of Obstetrics and Gynecology, 180:S57, 1999.

Miller VL, Ransom SB, Shalhoub A, Sokol RJ, Evans MI.  Multifetal Pregnancy Reduction:  Perinatal and Fiscal Outcomes.  Central Association of Obstetricians and Gynecologists.  1999 Annual Meeting, Maui, HI, October 25-30, 1999.

Monaghan, KM, Jackson CE, Feldman GL.  Genetic analysis of patients with pancreatitis and a history of alcohol abuse.  Genet in Med, 1:49.  1999.

Perry C, Nguyen M, Cypher M, Carlock L.  Strong correlation between polyglutamine repeat size in the huntington disease gene and the disease phenotype. Am Soc Neurochem, 30th Annual Meeting, New Orleans, LA. 1999.

Ransom SB, Mickelson IH, Makela PR, Essenmacher L, Evans MI.  The Quality of Cost-Effectiveness and Cost-Benefit Analyses in the Obstetrics and Gynecology Literature.  Central Association of Obstetricians and Gynecologists.  1999 Annual Meeting, Maui, HI, October 25-30, 1999.

Reddy U, Ayoub MA, Evans MI, Wapner RJ .  Multiple gestations:  Ultrasound diagnosis of trisomy 21.  Society for Maternal Fetal Medicine Annual Meeting. San Francisco, CA, January 18-23, 1999.  American Journal of Obstetrics and Gynecology, 180:S167, 1999.

Ruffin M, Brenner D, Reed B, Normele D. Gregoire L, Munkarah A, Kmak T, Lancaster WD. The potential use of HPV copy number and E6/E7 expression as biomarkers in cervical dysplasia.  American Association for Cancer Research, Philadelphia, PA. 1999.

Ryou C, Kadura I, Miller RE, Hadden TJ.  The glutamine synthetase intron-1 regulatory region includes a constitutive enhancer and two preadipocyte-specific silencers.  American Society for Biochemistry & Milecular Bilogy, 1999 Annual Meeting; San Francisco, CA May 16-20.  FASEB J 13, 1999

Salkowski A, Greb A, Al-Aouar R, Tromp G, Berguer R, Olson J, Kuivaniemi H.  Familial incidence of abdominal aortic aneurysms. J Genetic Counseling, 8:407, 1999.

Seubert DE, Feldman B, Krivchenia EL, Evans MI, Barki J, Johnson MP.  Molecular and fetal tissue biopsy capabilities are needed to maximize prenatal diagnosis of junctional epidermolysis bullosa (JEB):  Fetal skin biopsy using a 2mm microendoscope.  Society for Maternal Fetal Medicine Annual Meeting. San Francisco, CA, January 18-23, 1999.  American Journal of Obstetrics and Gynecology, 180:S182, 1999.

Shy ME, Krajewski K, Turansky C, Garbern J, Kamholz JA, Lewis R. CMT1A phenotype correlates with secondary axonal degeneration but not demyelination. Neurology 52:A217, 1999.

Srinivas PR, Cintron VJ, Sima AF, Grunberger G.  Primary cultures of vascular smooth muscle cells from the BB/W type 1 diabetic rat retain their hyperglycemic memory. Diabetes 48; Suppl 1: A132, 1999.

Thomas RA, Bergh S, Zhao J and Lyman WD.  A Novel Stem Cell Derived Gene Therapy for HIV/AIDS. A 1031, 1999 Pediatrics Academic Societies Ann Meeting, San Francisco, May 1-4, 1999.

Thomas RA, Krishnan M, Zacharova V, Zhao J, Lyman WD. Engineering Human Hematopoietic Stem Cells to Generate HIV-1 Replication Defective Cells. A 08, Center for Mol Med Scientific Retreat, Maumee Bay, November 19-20, 1999.

Thomas RA, Krishnan M, Zacharova V, Zhao J, Lyman WD. Transgene Mediated Gene Expression in CD34+ Human Hematopoietic Stem Cells. AB-4, Center for Mol Med Scientific Retreat, Maumee Bay, November 19-20, 1999.

Tomkiel J, Briscoe A Jr, Wakimoto B, Lindsley D.  Genetic and cytological characterization of a male-specific meiotic mutant that causes fourth chromosome nondisjunction.  40th Annual Drosophila Research Conference.  Bellevue, WA. 1999.

Tromp G, Vongpunsawad S, Kuivaniemi H, Ronkainen A, Hernesniemi J.  Analysis of candidate genes for intracranial aneurysms. Circulation, 99: 1117, 1999.

Wang X, Tromp G, Kuivaniemi H, Molina L, Serrano de la Pena L and Williams CJ. Physical and Transcript mapping of the Blau syndrome susceptibility locus. Am J Hum Genet, 65S: A422, 1999.

Womble DD.  GCG: The Wisconsin Package of Sequence Analysis Programs.  In Bioinformatics Methods and Protocols, Misener S and Krawetz SA, eds. Totowa, New Jersey: Humana Press, Inc.  pp. 3-22.

Womble DD.  Web-Based interfaces for the GCG Sequence Analysis Programs.  In Bioinformatics Methods and Protocols, Misener S and Krawetz SA, eds. Totowa, New Jersey: Humana Press, Inc. pp. 23-30.

Wykes S and Krawetz SA.  Is DNase I-hypersensitivity necessary for maintaining open chromatin domains. Center for Molecular Medicine & Genetics Wayne State University Scientific Retreat Maumee Bay C 11, 1999.

Yaron Y, Krivchenia EL, Cole LA, Leon J, Bradford S, Hallak M, Evans MI.  Urinary b-core fragment (BCF) of human chorionic gonadotropin (hCG) as a predictor of Down syndrome (DS):  Comparison with triple serum marker screening. Society for Maternal Fetal Medicine Annual Meeting.  San Francisco, CA, January 18-23, 1999.  American Journal of Obstetrics and Gynecology, 180:S57, 1999.

Yaron Y, Jaffa AJ, Har-Toov Y, Amster R, Gull I, Wolman I, Avrashi S, Lessing JB, Evans MI.  First trimester combined screening using nuchal translucency and maternal serum PAPP-A and free ß-hCG in the detection of chromosomal anomalies.  Society for Gynecologic Investigation, 46th Annual Meeting. Atlanta, GA, March 10-13, 1999. Journal of the Society for Gynecologic Investigation, 6:100A, 1999.

Yoon S, Tromp G, Olson M, Malcom GT, Strong JP and Kuivaniemi H. Association of a polymorphism in the gene for MMP13 with atherosclerosis. Am J Hum Genet, 65S: A403, 1999.

Zakarian VL, Loeb JA.  Regulation of neuregulin expression in embryonic motor neurons by target interactions.  Soc Neurosci Abs, 25:770, 1999.

Abstracts In Press

Al-Aouar R, Kuivaniemi H, Ronkainen A, Hernesniemi J, Ryynänen M, Majamaa K, Myllylä V, Myllylä R, Tromp G. Does vasodilator-stimulated phosphorprotein contribute to risk for intracranial aneurysm? Stroke (in press)

Baker C, Feldman B, Shalhoub AG, Ayoub MA, Evans MI.  Demographic determinants on the utilization of invasive genetic testing after multifetal pregnancy reduction (MFPR).  Society for Gynecologic Investigation Annual Meeting, March 22-25, 2000, Chicago, IL (poster).  (in press)

Chik L, Chik K, Spencer K, Sokol RJ, Krantz D, Johnson A, Macri JN, Evans MI.  An evalatuion of likelihood ratios for Down syndrome from maternal age, alpha-fetoprotein, and free beta human chorionic gonadotrophin.  Society for Maternal Fetal Medicine Annual Meeting, January 31-February 5, 2000, Miami, FL.  (in press)

Evans MI, Ayoub MA, Shalhoub AG, Feldman B, Yaron Y, Johnson A.  35% of couples declining multifetal pregnancy reduction spontaneously abort.  Society for Gynecologic Investigation Annual Meeting, March 22-25, 2000, Chicago, IL (poster).  (in press)

Evans MI, Henry G, Miller W, Bui T, Snijders R, Wapner R, Miny P, Johnson M, Peakman D, Johnson A, Nicolaides K, Holzgreve W, Ebrahim S, Jackson L.  Letter to the Editor.  Human Reproduction.  (in press)

Evans MI, Elias S, Bianchi D, Jackson L, Holzgreve W, de la Cruz F, Wapner RJ, Dukes KA, Klinger K, Krivchenia EL, Simpson JL.  Racial/ethnic confounders to the detection of Y signals in maternal blood in women carrying male fetuses:  The NIFTY Group Study.  Society for Gynecologic Investigation Annual Meeting, March 22-25, 2000, Chicago, IL (oral).  (in press)

Feldman B, Dotson LK, Johnson MP, Evans MI, Johnson A.  A comparison of misoprostol with carboprost for induction of second trimester genetic termination of pregnancy.  Society for Gynecologic Investigation Annual Meeting, March 22-25, 2000, Chicago, IL (poster).  (in press)

Feldman B, Qureshi F, Jacques SM, Fefalu MJV, Moran O, Shalhoub AG, Johnson MP, Johnson A, Evans MI.  Pathologic analysis of fetal specimens from dilatation and evacuation (D&E), for second trimester genetic termination of pregnancy.  Society for Gynecologic Investigation Annual Meeting, March 22-25, 2000, Chicago, IL (poster).  (in press)

Feldman B, Jacques SM, Qureshi F, Johnson MP, Johnson A, Evans MI.  Postabortion pathologic analysis is hampered by pretreatment induction of fetal cardiac asystole.  Society for Maternal Fetal Medicine Annual Meeting, January 31-February 5, 2000, Miami, FL.  (in press)

Feldman GL, Monaghan KG, Barbaratto GM, Snow, K.  The frequency and clinical significance of the S1235R mutation in the Cystic Fibrosis Transmembrane Conductance Regulator gene: results from a collaborative study.  Genet in Med  (in press)

Johnson A, Abella EM, Kukuruga DL, Whitten-Shurney W, Baynes RD, Lyman WD, Whitten CF, Evans MI.  In-utero transplantation of paternal CD34 enriched T-cell depleted hematopoietic stem cells for treatment of sickle cell anemia.  Society for Gynecologic Investigation Annual Meeting, March 22-25, 2000, Chicago, IL (poster).  (in press)

Johnson A, Tyagi R, Gilbert AD, Stockman PT, Bawle E, Evans MI, Treadwell MC, Zador IE.  Perinatal outcome in prenatally diagnosed situs inversus.  Society for Maternal Fetal Medicine Annual Meeting, January 31-February 5, 2000, Miami, FL.  (in press)

Ochshorn Y, Jaffa AJ, Evans MI, Orr-Urtreger A, Many A, Lessing JB, Yaron Y.  ROC-curve derived lower cutoff for first trioemster PAPP-A:  Increasing sensitivity for non-Down syndrome aneuploidy detection.  Society for Gynecologic Investigation Annual Meeting, March 22-25, 2000, Chicago, IL (oral).  (in press)

Sukkar N, Flore LA, Mohamed A, Ebrahim SAD, Evans MI, Johnson A.  Detection of a de novo unbalanced cryptic 6;21 translocation by fluorescence in situ hybridization (FISH) in a fetus with multiple congenital anomalies.  Society for Gynecologic Investigation Annual Meeting, March 22-25, 2000, Chicago, IL (poster).  (in press)

Case Reports Published

Feldman B, Kramer RL, Ebrahim SAD, Wolff DJ, Evans MI.  Prenatal evaluation of a de novo X;9 translocation.  American Journal of Medical Genetics 85(5):476-478, 1999.

Kramer RL, Feldman B, Ebrahim SA, Kasperski SB, Johnson MP, Evans MI.  Molecular cytogenetic analysis of a de novo 5q31q33 deletion associated with multiple congenital anomalies -a case report.  American Journal of Medical Genetics  82:143-145, 1999.

Yaron Y, Kramer RL, Feldman B, Kasperski SB, Vo T, Feldman GL, Johnson MP, Evans MI, Ebrahim SA.  Prenatal diagnosis of 46,XY/46,XX Mosaicism - A case report.   American Journal of Medical Genetics  84(1):12-14, 1999.

Patents and Intellectual Property

Lancaster WD, Gregoire L. ÒUse of Conserved Oligonucleotide Primers to Amplify Human Papillomavirus DNA SequencesÓ United States patent No. 5,863,717 issued January 26, 1999. (not previously reported).

Letters to the Editor

Bianchi DW, Simpson JL, Jackson LG, Evans MI, Elias S, Holzgreve W, Sullivan L, Cruz F, and DM-STAT on behalf of the NICHD Fetal Cell Study (NIFTY) Group. Letter to the Editor.  Prenatal Diagnosis 19(10):994-995, 1999.

Sokol AI, Kramer RL, Yaron Y, OÕBrien JE, Muller F, Johnson MP, Evans MI.  Letter to the Editor.  American Journal of Obstetrics and Gynecology 180(6):1598, 1999.

Tsai C-H, Van Dyke DL and Feldman GL.  Reply to the Letter to the Editor by Zackai-ÓDeletion 4q34.2Ó.  Am J Med Genet 86:198, 1999.