Features

Barbara Ann Karmanos Cancer Institute

Interim President: Vainutis Vaitkevicius, MD
2-Wertz Executive Office
4100 John R
(313) 993-7856

Articles Abella E and Ravindranath Y: Therapy for childhood acute myeloid leukemia: role of allogeneic bone marrow transplantation. Curr Oncol Rep 2:529-538, 2000

Adsay V, Logani S, Sarkar F, Crissman J and Vaitkevicius V: Foamy gland pattern of pancreatic ductal adenocarcinoma: a deceptively benign-appearing variant. Am J Surg Pathol 24:493-504, 2000

Adsay V, Klimstra D: Cystic forms of typically solid pancreatic tumors. Seminars in Diagnostic Pathology, 12:81-88, 2000.

Adsay V, Longnecker DS, Klimstra DS: Pancreatic tumors with cystic dilation of the ducts: “intraductal papillary mucinous neoplasms” and “intraductal oncocytic papillary neoplasms.” Seminars in Diagnostic Pathology, 17:16-30, 2000.

Adsay V, Hasteh F, Cheng JD, Klimstra DS: Squamous-lined cysts of the pancreas: lymphoepithelial cysts, dermoid cysts (teratomas) and accessory-splenic epidermoid cysts. Seminars in Diagnostic Pathology 17:56-65, 2000.

Ahmad I, Al-Katib AM, Beck FW and Mohammad RM: Sequential treatment of a resistant chronic lymphocytic leukemia patient with bryostatin 1 followed by 2-chlorodeoxyadenosine: case report. Clin Cancer Res 6:1328-1332, 2000

Ahmed S, Vaitkevicius VK, Zalupski MM, Du W, Arlauskas P, Gordon C, Kellogg C and Shields AF: Cisplatin, cytarabine, caffeine, and continuously infused 5- fluorouracil (PACE) in the treatment of advanced pancreatic carcinoma: a phase II study. Am J Clin Oncol 23:420-424, 2000

Alhasan SA, Ensley JF and Sarkar FH: Genistein induced molecular changes in a squamous cell carcinoma of the head and neck cell line. Int J Oncol 16:333-338, 2000

Ali MA, Kraut MJ, Valdivieso M, Wozniak AJ, Cummings G and Kalemkerian,GP: A phase II study of mitomycin C, etoposide, and cisplatin in advanced non-small cell lung cancer. Cancer Invest 18:1-5, 2000

Aranha O, Wood DP and Sarkar FH: Ciprofloxacin mediated cell growth inhibition, S/G2-M cell cycle arrest, and apoptosis in a human transitional cell carcinoma of the bladder cell line. Clin Cancer Res 6:891-900, 2000

Aref A, Thornton D, Youssef E, He T, Tekyi-Mensah S, Denton L and Ezzell G: Dosimetric improvements following 3D planning of tangential breast irradiation. Int J Radiat Oncol Biol Phys 48:1569-1574, 2000

Bacso Z, Everson RB and Eliason JF: The DNA of annexin V-binding apoptotic cells is highly fragmented. Cancer Res 60:4623-4628, 2000

Baer MR, Stewaart CC, Dodge RK, Leget GA, Sule N, Mrozek KA, Schiffer CA, Powell BL, Kolitz JE, Davey F, Carroll AJ, Larson RA, Bloomfield CD: High frequency of immunophenotype changes in acute myeloid leukemia at relapse: implications for minimal residual disease detection (CALGB study 8361). Blood (in press).

Bakshee S, Abella E, Baynes RD: Aplastic anemia. E-Medicine (in press).

Banerjee M, Biswas D, Sakr W and Wood DP: Recursive partitioning for prognostic grouping of patients with clinically localized prostate carcinoma. Cancer 89:404-411, 2000

Baris D, Brown LM, Silverman DT, Hayes R, Hoover RN, Swanson GM, Dosemeci M, Schwartz AG, Liff JM, Schoenberg JB, Pottern LM, Lubin J, Greenberg RS and Fraumeni JF: Socioeconomic status and multiple myeloma among US blacks and whites. Am J Public Health 90:1277-1281, 2000

Baynes RD, Dansey RD, Klein JL, Karanes C, Cassells L, Abella E, Wei WZ, Galy A, Du W, Wood G and Peters WP: High-dose chemotherapy and autologous stem cell transplantation for breast cancer. Cancer Invest 18:440-455, 2000

Baynes RD, Hamm C, Dansey R, Klein J, Cassells L, Karanes C, Abella E and Peters WP: Bone marrow and peripheral blood hematopoietic stem cell transplantation: focus on autografting. Clin Chem 46:1239-1251, 2000

Baynes RD, Dansey RD, Klein JK, Peters WP: High dose chemotherapy and peripheral blood progenitor cell transplantation in patients with breast cancer. The Oncologist 5:1-13, 2000.

Beck FW, Al-Katib AM, Ahmad I, Wall NR, Liu KZ, Mantsch HH and Mohammad, RM: Bryostatin 1-induced modulation of nucleoside transporters and 2- chlorodeoxyadenosine influx in WSU-CLL cells. Int J Mol Med 5:341-347, 2000

Ben-Josef E, Porter AT, Han S, Mertens W, Chuba P, Fontana J and Hussain M: Neoadjuvant estramustine and etoposide followed by concurrent estramustine and definitive radiotherapy for locally advanced prostate cancer: Feasibility and preliminary results. Int J Radiat Oncol Biol Phys 49:699-703, 2001

Bentley G, Dey J, Sakr WA, Wood DP, Pontes JE and Grignon DJ. Significance of the Gleason scoring system after neoadjuvant hormonal therapy. Mol Urol 4:125-;discussion 131, 2000

Brown LM, Gridley G, Pottern LM, Baris D, Swanson CA, Silverman DT, Hayes RB, Greenberg RS, Swanson GM, Schoenberg JB, Schwartz AG and Fraumeni JF, Jr: Diet and nutrition as risk factors for multiple myeloma among blacks and whites in the United States. Cancer Causes Control 12:117-125, 2001

Brush GS and Kelly TJ: Phosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint response. Nucleic Acids Res 28:3725-3732, 2000

Burack R.: Young teenagers’ attitudes towards general practitioners and their provision of sexual health care. Br J Gen Pract 50:550-554, 2000

Burack RC, George J and Gurney JG: Mammography use among women as a function of age and patient involvement in decision-making. J Am Geriatr Soc 48:817-821, 2000

Burack RC and Gimotty PA: Effectiveness of computerized reminders in ambulatory care. Jama 284:2872-2873, 2000

Burack RC, Simon MS, Stano M, George J and Coombs J: Follow-up among women with an abnormal mammogram in an HMO: is it complete, timely, and efficient? Am J Manag Care 6:1102-1113, 2000

Calaf G, Russo J, Tait L, Estrad S and Alvarado ME: Morphological phenotypes in neoplastic progression of human breast epithelial cells. J Submicrosc Cytol Pathol 32:83-96, 2000

Caruso JA, Reiners JJ, Jr, Emond J, Shultz T, Tainsky MA, Alaoui-Jamali M and Batist G: Genetic alteration of chromosome 8 is a common feature of human mammary epithelial cell lines transformed in vitro with benzo[a]pyrene. Mutat Res 473:85-99, 2001

Chandrasekar P, Abraham O, Klein J, Alangaden G, Chalasani G, Cassells L, Dansey R, Abella S, Karanes C, Peters W and Baynes R: Low infectious morbidity after intensive chemotherapy and autologous peripheral blood progenitor cell transplantation in the outpatient setting for women with breast cancer. Clin Infect Dis 32:546-551, 2001

Chandrasekar PH, Abraham OC, Klein J, Alangaden G, Chalasani G, Cassells L, Dansey R, Abella S, Karanes C, Peters W., Baynes R: Low infectious morbidity following intensive chemotherapy and autologous peripheral blood progenitor cell transplantation in the outpatient setting for women with breast cancer. Ann In Med (in press).

Chen C, Lin H and Chen BD: Bcl-2 antibodies induce hemoglobin release by red blood cells loaded with in vitro translated Bcl-2 and its cleaved fragment. Biochem Biophys Res Commun 270:816-820, 2000

Chen C, Lin H, Karanes C, Pettit GR and Chen BD: Human THP-1 monocytic leukemic cells induced to undergo monocytic differentiation by bryostatin 1 are refractory to proteasome inhibitor- induced apoptosis. Cancer Res 60:4377-4385, 2000

Cheson, BD, Abrams, J and Gravell, A. Clinical trials referral resource. Current cooperative group phase III clinical trials in early-stage breast cancer. Oncology (Huntingt) 15:176-177, 181-172, 185, 2001

Cheson, BD, Bennett, JM, Kantarjian, H, Pinto, A, Schiffer, CA, Nimer, SD, Lowenberg, B, Beran, M, de Witte, TM, Stone, RM, Mittelman, M, Sanz, GF, Wijermans, PW, Gore, S and Greenberg, PL. Report of an international working group to standardize response criteria for myelodysplastic syndromes. Blood 96:3671-3674, 2000

Chong BE, Yan F, Lubman DM and Miller FR: Chromato-focusing nonporous reversed-phase high-performance liquid chromatography/electrospray ionization time-of-flight mass spectrometry of proteins from human breast cancer whole cell lysates: a novel two- dimensional liquid chromatography/mass spectrometry method. Rapid Commun Mass Spectrom 15:291-296, 2001

Dansey R: Myelodysplasia. Curr Opin Oncol 12:13-21, 2000

Dansey RD and Baynes RD: Non-ablative allogeneic hematopoietic stem cell transplantation. Curr Opin Oncol 13:27-32, 2001

Davis JN, Muqim N, Bhuiyan M, Kucuk O, Pienta KJ and Sarkar FH: Inhibition of prostate specific antigen expression by genistein in prostate cancer cells. Int J Oncol 16:1091-1097, 2000

deAndrade M, Barnholtz JS, Amos CI, Adatto P, Spencer C, Bondy ML: Segregation analysis of cancer in families of glioma patients. Genetic Epidemiology (in press).

Ding BC, Whetstine JR, Witt TL, Schuetz JD and Matherly LH: Repression of Human Reduced Folate Carrier Gene Expression by Wild Type p53. J Biol Chem 276:8713-8719, 2001

Ding BC, Witt TL, Hukku B, Heng H, Zhang L, Matherly LH: Deletions and translocations of the reduced folate carrier gene are associated with profound loss of gene expression in methotrexate resistant K562 human erythroleukemia cells. Biochem Pharmacol (in press).

Djuric Z, Heilbrun LK, Lababidi S, Berzinkas E, Simon MS and Kosir MA: Levels of 5-hydroxymethyl-2’-deoxyuridine in DNA from blood of women scheduled for breast biopsy. Cancer Epidemiol Biomarkers Prev 10:147-149, 2001

Djuric z, Heilbrun LK, Lababidi S, Berzinkas E, Simon MS, Kosir MA: Levels of 5-Hydroxymethyl-2’-dexoyuridine in DNA from blood of women scheduled for breast biopsy. Cancer Epidemiology Biomarkers and Prevention (in press).

Du W, Touchette D, Vaitkevicius VK, Peters WP and Shields AF: Cost analysis of pancreatic carcinoma treatment. Cancer 89:1917-1924, 2000

Duanmu Z, Dunbar J, Falany CN and Runge-Morris M: Induction of rat hepatic aryl sulfotransferase (SULT1A1) gene expression by triamcinolone acetonide: impact on minoxidil-mediated hypotension. Toxicol Appl Pharmacol 164:312-320, 2000

Elias L, Lew D, Figlin RA, Flanigan RC, Thompson ME, Triozzi PL, Belt RJ, Wood DP, Rivkin SE and David E: Infusional interleukin-2 and 5-fluorouracil with subcutaneous interferon-alpha for the treatment of patients with advanced renal cell carcinoma: a southwest oncology group Phase II study. Cancer 89:597-603, 2000

Eliason JF, Greway A, Tare N, Inoue T, Bowen S, Dar M, Yamasaki M, Okabe M and Horii I: Extended activity in cynomolgus monkeys of a granulocyte colony- stimulating factor mutein conjugated with high molecular weight polyethylene glycol. Stem Cells 18:40-45, 2000

Evelhoch JL, Gillies RJ, Karczmar GS, Koutcher JA, Maxwell RJ, Nalcioglu O, Raghunand N, Ronen SM, Ross BD and Swartz HM: Applications of magnetic resonance in model systems: cancer therapeutics. Neoplasia 2:152-165, 2000

Farhana L, Boyanapalli M, Tschang SH, Sun RJ, Hsu CK, Zhang YX, Fontana JA and Rishi AK: Okadaic acid-mediated induction of the c-fos gene in estrogen receptor- negative human breast carcinoma cells utilized, in part, post-transcriptional mechanisms involving adenosine-uridine-rich elements. Cell Growth Differ 11:541-550, 2000

Ferlazzo G, Klein J, Paliard X, Wei WZ and Galy A: Dendritic cells generated from CD34+ progenitor cells with flt3 ligand, c-kit ligand, GM-CSF, IL-4, and TNF-alpha are functional antigen- presenting cells resembling mature monocyte-derived dendritic cells. J Immunother 23:48-58, 2000

Flaherty LE: Rationale for intergroup trial E-3695 comparing concurrent biochemotherapy with cisplatin, vinblastine, and DTIC alone in patients with metastatic melanoma. Cancer J Sci Am 6 Suppl 1:S15-20, 2000

Fleshner NE and Kucuk O: Antioxidant dietary supplements: Rationale and current status as chemopreventive agents for prostate cancer. Urology 57:90-94, 2001

Fontana JA, Dawson MI, Leid M, Rishi AK, Zhang Y, Hsu CA, Lu JS, Peterson VJ, Jong L, Hobbs P, Chao WR, Shroot B and Reichert U: Identification of a unique binding protein specific for a novel retinoid inducing cellular apoptosis. Int J Cancer 86:474-479, 2000

Fouad M, CorbieSmith G, Curb D, Howard B, Mouton C, Simon MS, Talbavera G, Thompson J, Wang C, White C, Young R: Special populations recruitment for the WHI: Successes and limitations. Clinical Journal of Women’s Health (in press).

Galy A, Christopherson I, Ferlazzo G, Liu G, Spits H and Georgopoulos K: Distinct signals control the hematopoiesis of lymphoid-related dendritic cells. Blood 95:128-137, 2000

Galy A, Rudraraju S, Baynes R and Klein J: Recovery of lymphocyte and dendritic cell subsets after autologous CD34+ cell transplantation. Bone Marrow Transplant 25:1249-1255, 2000

Geng H, Naylor PH, Dosescu J, Skunca M, Majumdar AP and Moshier JA: TGF alpha is required for full expression of the transformed growth phenotype of NIH 3T3 cells overexpressing ornithine decarboxylase. Carcinogenesis 21:567-572, 2000

Gillies RJ, Bhujwalla ZM, Evelhoch J, Garwood M, Neeman M, Robinson SP, Sotak CH and Van Der Sanden B: Applications of magnetic resonance in model systems: tumor biology and physiology. Neoplasia 2:139-151, 2000

Glazyrin AL, Sarkar FH: CD95 related apoptotic machinery is functional in pancreatic cancer cells. Pancreas (in press).

Grierson JR and Shields AF: Radiosynthesis of 3’-deoxy-3’-[(18)F]fluoro-thymidine: [(18)F]FLT for imaging of cellular proliferation in vivo. Nucl Med Biol 27:143-156, 2000

Gruber A, Kan-Mitchell J, Kuhen KL, Mukai T and Wong-Staal F: Dendritic cells transduced by multiply deleted HIV-1 vectors exhibit normal phenotypes and functions and elicit an HIV-specific cytotoxic T- lymphocyte response in vitro. Blood 96:1327-1333, 2000

Guan HP, Ksebati MB, Cheng YC, Drach JC, Kern ER and Zemlicka J.:Spiropentane mimics of nucleosides: analogues of 2’-deoxyadenosine and 2’-deoxyguanosine. Synthesis of all stereoisomers, isomeric assignment, and biological activity. J Org Chem 65:1280-1290, 2000

Guan HP, Ksebati MB, Kern ER and Zemlicka J: Approaches to unsaturated analogues of nucleosides comprising four- and six-membered rings. J Org Chem 65:5177-5184, 2000

Haga A, Niinaka Y and Raz, A: Phosphohexose isomerase/autocrine motility factor/neuroleukin/maturation factor is a multifunctional phosphoprotein. Biochem Biophys Acta 1480:235-244, 2000

Hayes RB, Pottern LM, Strickler H, Rabkin C, Pope V, Swanson GM, Greenberg, RS, Schoenberg JB, Liff, J, Schwartz AG, Hoover RN and Fraumeni JF: Sexual behavior, STDs and risks for prostate cancer. Br J Cancer 82:718-725, 2000

He Z, Evelhoch JL, Mohammad RM, Adsay NV, Pettit GR, Vaitkevicius VK and Sarkar F: Magnetic resonance imaging to measure therapeutic response using an orthotopic model of human pancreatic cancer. Pancreas 21:69-76, 2000

Hensley ML, Peterson, B, Silver RT, Larson RA, Schiffer CA and Szatrowski TP: Risk factors for severe neuropsychiatric toxicity in patients receiving interferon alfa-2b and low-dose cytarabine for chronic myelogenous leukemia: analysis of Cancer and Leukemia Group B 9013. J Clin Oncol 18:1301-1308, 2000

Heppner GH, Miller FR and Malathy Shekhar P: Non-transgenic models of breast cancer. Breast Cancer Res 2:331-334, 2000

Hillman GG, Forman JD, Kucuk O, Yudelev, M, Maughan RL, Rubio J, Layer A, Tekyi-Mensah S, Abrams J and Sarkar FH: Genistein potentiates the radiation effect on prostate carcinoma cells. Clin Cancer Res 7:382-390, 2001

Hillman GG, Maughan RL, Grignon DJ, Yudelev M, Rubio J, Tekyi-Mensah S, Layer A, Che M and Forman JD: Neutron or photon irradiation for prostate tumors: enhancement of cytokine therapy in a metastatic tumor model. Clin Cancer Res 7:136-144, 2001

Honjo Y, Inohara H, Akahani, S, Yoshii T, Takenaka Y, Yoshida J, Hattori K, Tomiyama Y, Raz A and Kubo T: Expression of cytoplasmic galectin-3 as a prognostic marker in tongue carcinoma. Clin Cancer Res 6:4635-4640, 2000

Hooser SB, McCarthy JM, Wilson CR, Harms JL, Stevenson G and Everson RJ: Effects of storage conditions and hemolysis on vitamin E concentrations in porcine serum and liver. J Vet Diagn Invest 12:365-368, 2000

Hukku B, Mally M, Cher ML, Peeh DM, Kung H and Rhim JS: Stepwise genetic changes associated with progression of nontumorigenic HPV-18 immortalized human prostate cancer-derived cell line to a malignant phenotype. Cancer Genet Cytogenet 120:117-126, 2000

Hussain M, Fisher EI, Petrylak DP, O’Connor J, Wood DP, Small EJ, Eisenberger MA and Crawford ED: Androgen deprivation and four courses of fixed-schedule suramin treatment in patients with newly diagnosed metastatic prostate cancer: A Southwest Oncology Group Study. J Clin Oncol 18:1043-1049, 2000

Hussain MH, Glass TR, Forman J, Sakr W, Smith DC, Al-Sarraf M, Jones J, Balcerzak SP, Crawford ED and Grossman HB: Combination cisplatin, 5-fluorouracil and radiation therapy for locally advanced unresectable or medically unfit bladder cancer cases: a Southwest Oncology Group Study. J Urol 165:56-60; discussion 60-51, 2001

Jefcoate CR, Liehr JG, Santen RJ, Sutter TR, Yager JD, Yue W, Santner SJ, Tekmal R, Demers L, Pauley R, Naftolin F, Mor G and Berstein L: Tissue-specific synthesis and oxidative metabolism of estrogens. J Natl Cancer Inst Monogr 27:95-112, 2000

Ji BT, Silverman DT, Stewart PA, Blair A, Swanson GM, Baris D, Greenberg RS, Hayes RB, Brown LM, Lillemoe KD, Schoenberg JB, Pottern LM, Schwartz AG and Hoover RN: Occupational exposure to pesticides and pancreatic cancer. Am J Ind Med 39:92-99, 2001

Jimenez RE, Gheiler E, Oskanian P, Tiguert R, Sakr W, Wood DP, Pontes JE and Grignon DJ: Grading the invasive component of urothelial carcinoma of the bladder and its relationship with progression-free survival. Am J Surg Pathol 24:980-987, 2000

Kato I, Dnistrian AM, Schwartz M, Toniolo P, Koenig K, Shore RE, Zeleniuch-Jacquotte A, Akhmedkhanov A and Riboli E: Risk of iron overload among middle-aged women. Int J Vitam Nutr Res 70:119-125, 2000

Kato I, Toniolo P, Zeleniuch-Jacquotte A, Shore RE, Koenig, KL: Akhmedkhanov, A and Riboli, E. Diet, smoking and anthropometric indices and postmenopausal bone fractures: a prospective study. Int J Epidemiol 29:85-92, 2000

Kato I, Zeleniuch-Jacquotte A, Toniolo PG, Akhmedkhanov A, Koenig K and Shore R: Psychotropic medication use and risk of hormone-related cancers: the New York University Women’s Health Study. J Public Health Med 22:155-160, 2000

Kaur J, Turner JR, Singh P and Al-Katib A: Multiple myeloma in the liver. Am J Hematol 65:290, 2000

Kelley, MJ, Jawien, W, Lin, A, Hoffmeister, K, Pugh, EW, Doheny, KF and Korczak, JF. Autosomal dominant macrothrombocytopenia with leukocyte inclusions (May- Hegglin anomaly) is linked to chromosome 22q12-13. Hum Genet 106:557-564, 2000

Kelley, MJ, Jawien, W, Ortel, TL and Korczak, JF. Mutation of MYH9, encoding non-muscle myosin heavy chain A, in May- Hegglin anomaly. Nat Genet 26:106-108, 2000

Keyes KA, Albella B, LoRusso PM, Bueren JA and Parchment RE: Cytotoxic chemotherapy regimens that increase dose per cycle (dose intensity) by extending daily dosing from 5 consecutive days to 28 consecutive days and beyond. Clin Cancer Res 6:2474-2481, 2000

Kim HE, Krug MA, Han I, Ensley J, Yoo GH, Forman JD and Kim HR: Neutron radiation enhances cisplatin cytotoxicity independently of apoptosis in human head and neck carcinoma cells. Clin Cancer Res 6:4142-4147, 2000

Kirkwood JM, Ibrahim JG, Sondak VK, Richards J, Flaherty LE, Ernstoff MS, Smith TJ, Rao U, Steele M and Blum RH: High- and low-dose interferon alfa-2b in high-risk melanoma: first analysis of intergroup trial E1690/S9111/C9190. J Clin Oncol 18:2444-2458, 2000

Klein JL, Rey PM, Dansey RD, Karanes C, Du W, Abella E, Cassells L, Hamm C, Peters WP and Baynes RD: Cardiac sequelae of doxorubicin and paclitaxel as induction chemotherapy prior to high-dose chemotherapy and peripheral blood progenitor cell transplantation in women with high-risk primary or metastatic breast cancer. Bone Marrow Transplant 25:1047-1052, 2000

Kosir MA, Rymal C, Koppolu P, Hryniuk L, Darga L, Du W, Rice V, Mood D, Shakoor S, Wang W, Bedoyan J, Aref A, Biernat L and Northouse L: Surgical outcomes after breast cancer surgery: measuring acute lymphedema. J Surg Res 95:147-151, 2001

Krag D, Ashikaga T and Abrams J: Sentinel nodes: clinical trial data needed. J Clin Oncol 18:3873-3874, 2000

Krug LM, Miller VA, Kalemkerian GP, Kraut MJ, Ng KK, Heelan RT, Pizzo BA, Perez W, McClean N and Kris MG: Phase II study of dolastatin-10 in patients with advanced non-small- cell lung cancer. Ann Oncol 11:227-228, 2000

Kucuk O, Kilton L, Wade JL, Blough R and Benson AB: 3^rd. Phase II trial of menogaril in patients with previously treated multiple myeloma or chronic lymphocytic leukemia. Am J Clin Oncol 23:379-383, 2000

Kucuk O, Shevrin DH, Pandya KJ and Bonomi PD: Phase II trial of cisplatin, etoposide, and 5-fluorouracil in advanced non-small-cell lung cancer: an Eastern Cooperative Oncology Group Study (PB586). Am J Clin Oncol 23:371-375, 2000

Kucuk O, Young ML, Habermann TM, Wolf BC, Jimeno J and Cassileth PA: Phase II trial of vitamin B in previously treated non-Hodgkin’s lymphoma: an Eastern Cooperative Oncology Group (ECOG) Study. Am J Clin Oncol 23:273-277, 2000

Kucuk ON, Aras G, Soylu A, Ozcan M, Ibis E, Akin A, Kir MK, Erbay G and Tokuz G: Uptake of Tc-99m human immunoglobulin in malignant abdominal lymphoma. Clin Nucl Med 25:227-228, 2000

Lagana A, Duchaine T, Raz A, DesGroseillers L and Nabi IR: Expression of autocrine motility factor/phosphohexose isomerase in Cos7 cells. Biochem Biophys Res Commun 273:213-218, 2000

Le PU, Benlimame N, Lagana A, Raz A and Nabi IR: Clathrin-mediated endocytosis and recycling of autocrine motility factor receptor to fibronectin fibrils is a limiting factor for NIH-3T3 cell motility. J Cell Sci 113:3227-3240, 2000

Lechner LF, Schwartz AG: Speculations on the mechanisms of inter-individual susceptibility for cancer risk. Rad Res (in press).

Leethanakul C, Patel V, Gillespie J, Pallente M, Ensley JF, Koontongkaew S, Liotta LA, Emmert-Buck M and Gutkind JS: Distinct pattern of expression of differentiation and growth-related genes in squamous cell carcinomas of the head and neck revealed by the use of laser capture micro-dissection and cDNA arrays. Oncogene 19:3220-3224, 2000

Leethanakul C, Patel V, Gillespie J, Shillitoe E, Kellman RM, Ensley JF, Limwongse V, Emmert-Buck MR, Krizman DB and Gutkind JS: Gene expression profiles in squamous cell carcinomas of the oral cavity: use of laser capture micro-dissection for the construction and analysis of stage-specific cDNA libraries. Oral Oncology 36:474-483, 2000

Li Y, Bhuiyan M, Alhasan S, Senderowic AM and Sarkar FH: Induction of apoptosis and inhibition of c-erbB-2 in breast cancer cells by flavopiridol. Clin Cancer Res 6:223-229, 2000

Li Y, Chinni SR, Senderowicz AM and Sarkar FH: Induction of growth inhibition and apoptosis in prostate cancer cells by flavopiridol. Int J Oncol 17:755-759, 2000

Lim EH, Shields AF: The role of PET scanning the non-small cell lung cancer. J of Oncology Index & Reviews, IV (number 4):3-5, 2001.

Lin H, Chen C and Chen BD: Resistance of bone marrow-derived macrophages to apoptosis is associated with the expression of X-linked inhibitor of apoptosis protein in primary cultures of bone marrow cells. Biochem J 353:299-306, 2001

Lin H, Zhang XM, Chen C and Chen BD: Apoptosis of Mo7e leukemia cells is associated with the cleavage of Bcl- 2 into a shortened fragment that is not functional for heterodimerization with Bcl-2 and Bax. Exp Cell Res 261:180-186, 2000

Liu CY, Yim BT and Wozniak AJ: Anticoagulation therapy for radiation-induced myelopathy. Ann Pharmacother 35:188-191, 2001

Lorusso PM: Oxaliplatin in tumors other than colorectal cancer. Oncology 14:33-37, 2000

LoRusso PM, Foster BJ, Wozniak A, Heilbrun LK, McCormick JI, Ruble PE, Graham MA, Purvis J, Rake J, Drozd M, Lockwood GF and Corbett TH: Phase I pharmacokinetic study of the novel antitumor agent SR233377. Clin Cancer Res 6:3088-3094, 2000

Mabrie DC, Francis HW, Zinreich SJ, Sciubba J and Yoo GH: Imaging quiz case 4. Dentigerous cyst. Arch Otolaryngol Head Neck Surg 126:1269, 1272-1263, 2000

MacGregor JT, Collins JM, Sugiyama Y, Tyson CA, Dean J, Smith L, Andersen M, Curren RD, Houston JB, Kadlubar FF, Kedderis GL, Krishnan K, Li AP, Parchment RE, Thummel K, Tomaszewski JE, Ulrich R, Vickers AE and Wrighton SA: In vitro human tissue models in risk assessment: report of a consensus- building workshop. Toxicol Sci 59:17-36, 2001

Mandalfino P, Rice G, Smith A, Klein JL, Rystedt L and Ebers GC: Bone marrow transplantation in multiple sclerosis. J Neurol 247:691-695, 2000

Mankoff DA, Dehdashti F and Shields AF: Characterizing tumors using metabolic imaging: PET imaging of cellular proliferation and steroid receptors. Neoplasia 2:71-88, 2000

Mao H, Liu H, Fu X, Fang Z, Abrams, J and Worsham MJ: Loss of nm23 expression predicts distal metastases and poorer survival for breast cancer. Int J Oncol 18:587-591, 2001

Mathews ST, Chellam N, Srinivas PR, Cintron VJ, Leon MA, Goustin AS and Grunberger G: Alpha2-HSG, a specific inhibitor of insulin receptor autophosphorylation, interacts with the insulin receptor. Mol Cell Endocrinol 164:87-98, 2000

Mathews ST, Cintron V, Qiang X, Singh GP, Jahnen-Dechent W, Goustin AS and Grunberger G: Enhanced glucose clearance and insulin sensitivity in fetuin-deficient mice. J Diabetes Complications 15:23, 2001

Mazurek N, Conklin J, Byrd JC, Raz A and Bresalier RS: Phosphorylation of the beta-galactoside-binding protein galectin-3 modulates binding to its ligands. J Biol Chem 275:36311-36315, 2000

Melgar T, Schubiner H, Burack R, Aranha A and Musial J: A time-motion study of the activities of attending physicians in an internal medicine and internal medicine-pediatrics resident continuity clinic. Acad Med 75:1138-1143, 2000

Miller FR, Santner SJ, Tait L and Dawson PJ: MCF10DCIS.com xenograft model of human comedo ductal carcinoma in situ. J Natl Cancer Inst 92:1185-1186, 2000

Minev BR, Chavez FL, Dudouet BM and Mitchell MS: Synthetic insertion signal sequences enhance MHC class I presentation of a peptide from the melanoma antigen MART-1. Eur J Immunol 30:2115-2124, 2000

Mitchell MS, Kan-Mitchell J, Minev B, Edman C and Deans RJ: A novel melanoma gene (MG50) encoding the interleukin 1 receptor antagonist and six epitopes recognized by human cytolytic T lymphocytes. Cancer Res 60:6448-6456, 2000

Mohammad RM, Wall NR, Dutcher JA and Al-Katib AM: The addition of bryostatin 1 to cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy improves response in a CHOP-resistant human diffuse large cell lymphoma xenograft model. Clin Cancer Res 6:4950-4956, 2000

Moore RD, Charache S, Terrin ML, Barton FB, Ballas SK and the Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia. Cost-effective of hydroxyurea in sickle cell anemia. Am J Hematol, 64:26-31, 2000.

Morrissey C, Lakins J, Moquin A, Hussain M, Tenniswood M: An antigen capture assay for the measurement of serum clusterin concentrations. J Biochemical and Biological Methods (in press).

Nabha SM, Wall NR, Mohammad RM, Pettit GR and Al-Katib AM: Effects of combretastatin A-4 prodrug against a panel of malignant human B-lymphoid cell lines. Anticancer Drugs 11:385-392, 2000

Nabha SM, Wall N, Mohammad RM, Pettit GR, Al-Katib A: Effects of comberetastatin A-4 pro-drug against a panel of malignant human B-lymphoid cell lines. Anti-Cancer Drugs, 11:31-40, 2000.

Nangia-Makker P, Baccarini S and Raz A” Carbohydrate-recognition and angiogenesis. Cancer Metastasis Rev 19:51-57, 2000

Nangia-Makker P, Honjo Y, Sarvis R, Akahani S, Hogan V, Pienta KJ and Raz A: Galectin-3 induces endothelial cell morphogenesis and angiogenesis. Am J Pathol 156:899-909, 2000

Narain V, Tiguert R, Banerjee M, Grignon D, Wood DP and Powell IJ:Biochemical recurrence after radical prostatectomy in black and white American men with a positive or negative family history of prostate cancer. J Urol 165:474-477, 2001

Nathanson SD, Zarbo RJ, Wachna DL, Spence CA, Andrzejewski TA and Abrams J: Microvessels that predict axillary lymph node metastases in patients with breast cancer. Arch Surg 135:586-593; discussion 593-584, 2000

Negrin RS, Atkinson, K, Leemhuis, T, Hanania E, Juttner C, Tierney K, Hu WW, Johnston LJ, Shizurn JA, Stockerl-Goldstein KE, Blume KG, Weissman IL, Bower S, Baynes R, Dansey R, Karanes C, Peters W and Klein J: Transplantation of highly purified CD34+Thy-1+ hematopoietic stem cells in patients with metastatic breast cancer. Biol Blood Marrow Transplant 6:262-271, 2000

Newman L, Carolin K, Bouwman D, Simon MS, Peters W, Demers RY, Schwartz AG, Visscher D: Impact of breast cancer on African American women: The Detroit experience. Cancer (in press).

Nicholson RH, Pantano S, Eliason JF, Galy A, Weiler S, Kaplan J, Hughes MR and Ko MS: Phemx, a novel mouse gene expressed in hematopoietic cells maps to the imprinted cluster on distal chromosome 7. Genomics 68:13-21, 2000

Northouse LL, Mood D, Templin T, Mellon S and George T: Couples’ patterns of adjustment to colon cancer. Soc Sci Med 50:271-284, 2000

Ozer H, Armitage, JO, Bennett CL, Crawford J, Demetri GD, Pizzo PA, Schiffer CA, Smith TJ, Somlo G, Wade JC, Wade JL, Winn RJ, Wozniak AJ: and Somerfield, MR. 2000 update of recommendations for the use of hematopoietic colony- stimulating factors: evidence-based, clinical practice guidelines. American Society of Clinical Oncology Growth Factors Expert Panel. J Clin Oncol 18:3558-3585, 2000

Pacis RA, Pilat MJ, Pienta KJ, Wojno K, Raz A, Hogan V and Cooper CR: Decreased galectin-3 expression in prostate cancer. Prostate 44:118-123, 2000

Patel V, Ensley JF, Gutkind JS and Yeudall WA: Induction of apoptosis in head-and-neck squamous carcinoma cells by gamma-irradiation and bleomycin is p53-independent. Int J Cancer 88:737-743, 2000

Patel V, Ensley JF, Robbins KC, Yeudall WA: Over-expression of laminin-5 in SCCHN. Oral Oncology (in press).

Patel V, Ensley J, Gutkind S, Yeudall A: Induction of apoptosis in head and neck carcinomas by gamma-irradiation and bleomycin in P53 independent. Int J Cancer (in press).

Pauley RJ, Santner SJ, Tait LR, Bright RK and Santen RJ: Regulated CYP19 aromatase transcription in breast stromal fibroblasts. J Clin Endocrinol Metab 85:837-846, 2000

Pereira SJ, O’Brien DP, Luchette FA, Choe KA, Lim E, Davis Jr, K, Hurst JM, Johannigman JA and Frame SB: Dynamic helical computed tomography scan accurately detects hemorrhage in patients with pelvic fracture. Surgery 128:678-685, 2000

Peters WP, Baynes RD, Cassells L, Dansey RD, Klein JL, Hamm C, Karanes C, Abella E: Outpatients transplantation. Oncology 14:191-102, 2000.

Philip PA and Flaherty LE: Biochemotherapy for melanoma. Curr Oncol Rep 2:314-321, 2000

Powell IJ, Banerjee M, Novallo M, Sakr W, Grignon D, Wood DP and Pontes JE: Prostate cancer biochemical recurrence stage for stage is more frequent among African-American than white men with locally advanced but not organ-confined disease. Urology 55:246-251, 2000

Powell IJ, Banerjee M, Novallo M, Sakr W, Grignon D, Wood DP and Pontes JE: Should the age specific prostate specific antigen cutoff for prostate biopsy be higher for black than for white men older than 50 years? J Urol 163:146-148; discussion 148-149, 2000

Prakash S, Foster BJ, Meyer M, Wozniak A, Heilbrun LK, Flaherty L, Zalupski M, Radulovic L, Valdivieso M and LoRusso PM: Chronic oral administration of CI-994: a phase 1 study. Invest New Drugs 19:1-11, 2001

Qiu YL, Geiser F, Kira T, Gullen E, Cheng YC, Ptak RG, Breitenbach JM, Drach JC, Hartline CB, Kern ER and Zemlicka J: Synthesis and enantioselectivity of the antiviral effects of (R,Z)- ,(S,Z)-methylenecyclopropane analogues of purine nucleosides and phosphoralaninate prodrugs: influence of heterocyclic base, type of virus and host cells. Antivir Chem Chemother 11:191-202, 2000

Qui YL, Ksebati MB and Zemlicka J: Synthesis of (Z)- and (E)-9-[(2-hydroxyethylidene)cyclopropyl]adenine—new methylenecyclopropane analogues of adenosine and their substrate activity for adenosine deaminase. Nucleosides Nucleotides Nucleic Acids 19:31-37, 2000

Rahman KM, Aranha O, Glazyrin A, Chinni SR and Sarkar FH: Translocation of Bax to mitochondria induces apoptotic cell death in indole-3-carbinol (I3C) treated breast cancer cells. Oncogene 19:5764-5771, 2000

Rai KR, Peterson BL, Appelbaum FR, Kolitz J, Elias L, Shepherd L, Hines J, Threatte GA, Larson RA, Cheson BD and Schiffer CA: Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia. N Engl J Med 343:1750-1757, 2000

Resnick LM, Militianu D, Cunnings AJ, Pipe JG, Evelhoch JL, Soulen RL and Lester MA: Pulse waveform analysis of arterial compliance: relation to other techniques, age, and metabolic variables. Am J Hypertens 13:1243-1249, 2000

Roh HJ, Shin DM, Lee JS, Ro JY, Tainsky MA, Hong WK and Hittelman WN: Visualization of the timing of gene amplification during multi-step head and neck tumorigenesis. Cancer Res 60:6496-6502, 2000

Rose EA, Deshikachar A, Schwartz K, Severson RK: Use of a template to improve decision-making in evaluation and treatment of pharyngitis. Fam Med (in press).

Rusch VW, Giroux DJ, Kraut MJ, Crowley J, Hazuka M, Johnson D, Goldberg M, Detterbeck F, Shepherd F, Burkes R, Winton T, Deschamps C, Livingston R and Gandara D: Induction chemoradiation and surgical resection for non-small cell lung carcinomas of the superior sulcus: Initial results of Southwest Oncology Group Trial 9416 (Intergroup Trial 0160). J Thorac Cardiovasc Surg 121:472-483, 2001

Rybak RJ, Hartline CB, Qiu YL, Zemlicka J, Harden E, Marshall G, Sommadossi JP and Kern ER: In vitro activities of methylenecyclopropane analogues of nucleosides and their phosphoralaninate prodrugs against cytomegalovirus and other herpesvirus infections. Antimicrob Agents Chemother 44:1506-1511, 2000

Sadler GR, Oberle-Edwards L, Farooqi, A and Hryniuk WM: Oral sequelae of chemotherapy: an important teaching opportunity for oncology health care providers and their patients. Support Care Cancer 8:209-214, 2000

Said HM, Chatterjee N, Haq RU, Subramanian VS, Ortiz A, Matherly LH, Sirotnak FM, Halsted C and Rubin SA: Adaptive regulation of intestinal folate uptake: effect of dietary folate deficiency. Am J Physiol Cell Physiol 279:C1889-1895, 2000

Sakr WA, Tefilli MV, Grignon DJ, Banerjee M, Dey J, Gheiler EL, Tiguert R, Powell IJ and Wood DP: Gleason score 7 prostate cancer: a heterogeneous entity? Correlation with pathologic parameters and disease-free survival. Urology 56:730-734, 2000

Sanchez-Cespedes M, Esteller M, Wu L, Nawroz-Danish H, Yoo GH, Koch WM, Jen J, Herman JG and Sidransky D: Gene promoter hypermethylation in tumors and serum of head and neck cancer patients. Cancer Res 60:892-895, 2000

Sandler AB, Kindler HL, Einhorn LH, Mitchell E, Masters G, Kraut M, Nicol S and Raghavan D: Phase II trial of gemcitabine in patients with previously untreated metastatic cancer of the esophagus or gastroesophageal junction. Ann Oncol 11:1161-1164, 2000

Scherthan H, Jerratsch M, Dhar S, Wang YA, Goff SP and Pandita TK: Meiotic telomere distribution and Sertoli cell nuclear architecture are altered in Atm- and Atm-p53-deficient mice. Mol Cell Biol 20:7773-7783, 2000

Schiffer CA: Leukemia. Curr Opin Oncol 13:1-2, 2001

Schiffer CA, Anderson KC, Bennett CL, Bernstein S, Elting LS, Goldsmith M, Goldstein M, Hume H, McCullough JJ, McIntyre RE, Powell BL, Rainey JM, Rowley SD, Rebulla P, Troner MB and Wagnon AH: Platelet transfusion for patients with cancer: clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 19:1519-1538, 2001

Schiffer CA, Miller K, Larson RA, Amrein PC, Antin JH, Zani VJ and Stone RM: A double-blind, placebo-controlled trial of pegylated recombinant human megakaryocyte growth and development factor as an adjunct to induction and consolidation therapy for patients with acute myeloid leukemia. Blood 95:2530-2535, 2000

Schmelz EM, Sullards MC, Dillehay DL and Merrill AH: Colonic cell proliferation and aberrant crypt foci formation are inhibited by dairy glycosphingolipids in 1, 2-dimethylhydrazine-treated CF1 mice. J Nutr 130:522-527, 2000

Shekarriz B, Tiguert R, Upadhyay J, Gheiler E, Powell IJ, Pontes JE, Grignon DJ, Sakr W and Wood DP: Impact of location and multifocality of positive surgical margins on disease-free survival following radical prostatectomy: a comparison between African-American and white men. Urology 55:899-903, 2000

Shekarriz H, Shekarriz B, Upadhyay J, Burk C, Wood DP and Bruch HP: Hydro-jet assisted laparoscopic partial nephrectomy: initial experience in a porcine model. J Urol 163:1005-1008, 2000

Shekhar MP, Werdell J, Santner SJ, Pauley RJ and Tait L: Breast stroma plays a dominant regulatory role in breast epithelial growth and differentiation: implications for tumor development and progression. Cancer Res 61:1320-1326, 2001

Shekhar MP, Werdell J and Tait L: Interaction with endothelial cells is a prerequisite for branching ductal-alveolar morphogenesis and hyperplasia of preneoplastic human breast epithelial cells: regulation by estrogen. Cancer Res 60:439-449, 2000

Shibuya TY, Wei WZ, Zormeier M, Ensley J, Sakr W, Mathog RH, Meleca RJ, Yoo GH, June CH, Levine BL and Lum LG: Anti-CD3/anti-CD28 bead stimulation overcomes CD3 unresponsiveness in patients with head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 126:473-479, 2000

Shields AF, Lange LM and Zalupski MM: Phase II study of liposomal doxorubicin in patients with advanced colorectal cancer. Am J Clin Oncol 24:96-98, 2001

Shillitoe EJ, May M, Patel V, Lethanakul C, Ensley JF, Strausberg RL and Gutkind JS: Genome-wide analysis of oral cancer—early results from the Cancer Genome Anatomy Project. Oral Oncol 36:8-16, 2000

Silverman DT, Hoover RN, Brown LM, Swanson GM, Schiffman m, Greenberg RS, Hayes RB, Lillemoe KD, Schoenberg, JB, Schwartz AG, Liff J, Poettern LM, Fraumeni Jr JF: Why do Black Americans have a higher risk of pancreatic cancer than White Americans? J Amer Medical Assoc (in press).

Simon MS, Gimotty PA, Moncrease, A, Dews, P and Burack, RC. The effect of patient reminders on the use of screening mammography in an urban health department primary care setting. Breast Cancer Res Treat 65:63-70, 2001

Simon, MS, Heilbrun, LK, Stephens D, Lababidi S and Djuric Z: Recruitment for a pilot case control study of oxidative DNA damage and breast cancer risk. Am J Clin Oncol 23:283-287, 2000

Simon MS, Djuric Z, Dunn B, Stephens D, Lababidi S, Heilbrun LK: An evaluation of plasma antioxidant levels and the risk of breast cancer: A pilot case control study. The Breast Journal (in press).

Simon MS, Gimotty PA, Moncrease A, Dews P, Burack RC: The effect of patient reminders on the use of screening mammography in an urban health department primary care setting. Breast Cancer Research and Treatment (in press).

Sloan A, Dansey R, Zamorano L, Barger G, Hamm C, Diaz F, Baynes R and Wood D: Adoptive immunotherapy in patients with recurrent malignant glioma: Preliminary results using autologous whole-tumor vaccine and granulocyte-macrophage colony-stimulating factor and adoptive transfer of anti-CD3 activated lymphocytes. Neurosurgical Focus 9:1-8, 2000

Sondak VK and Flaherty LE: Adjuvant high-dose interferon revisited. Cancer J Sci Am 6:132-134, 2000

Steinbrecher KA, Tuohy TM, Heppner Goss K, Scott, MC, Witte DP, Groden J and Cohen MB: Expression of guanylin is downregulated in mouse and human intestinal adenomas. Biochem Biophys Res Commun 273:225-230, 2000

Stone RM, Bert DT, George SL, Dodge RK, Paciucci PA, Schulman PP, Lee EJ, Moore JO, Powell BL, Baer MR, Bloomfield CD, Schiffer CA: Post remission therapy in older patients with de novo acute myeloid leukemia (AML): A randomized trial comparing mitoxantrone/intermediate dose cytarabine with standard dose cytarabine (CALGB study 8923). Blood (in press).

Strickland LB, Dawson PJ, Santner SJ and Miller FR: Progression of premalignant MCF10AT generates heterogeneous malignant variants with characteristic histologic types and immunohistochemical markers. Breast Cancer Res Treat 64:235-240, 2000

Sun SY, Yue P, Zhou JY, Wang Y, Choi Kim HR, Lotan R and Sheng Wu G: Over-expression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells. Biochem Biophys Res Commun 280:788-797, 2001

Tallman MS, Andersen JW, Schiffer CA, Appelbaum FR, Feusner JH, Ogden A, Shepherd L, Rowe JM, Francois C, Larson RS and Wiernik PH: Clinical description of 44 patients with acute promyelocytic leukemia who developed the retinoic acid syndrome. Blood 95:90-95, 2000

Talukder AH, Adam L, Raz A and Kumar R: Heregulin regulation of autocrine motility factor expression in human tumor cells. Cancer Res 60:474-480, 2000

Taub JW, Huang X, Ge Y, Dutcher JA, Stout ML, Mohammad RM, Ravindranath, Y and Matherly LH: Cystathionine-beta-synthase cDNA transfection alters the sensitivity and metabolism of 1-beta-D-arabinofuranosylcytosine in CCRF-CEM leukemia cells in vitro and in vivo: a model of leukemia in Down syndrome. Cancer Res 60:6421-6426, 2000

Tiguert R, Gheiler EL, Grignon DJ, Littrup PJ, Sakr W, Pontes JE and Wood DP: Patients with abnormal ultrasound of the prostate but normal digital rectal examination should be classified as having clinical stage T2 tumors. J Urol 163:1486-1490, 2000

Toniolo P, Van Kappel AL, Akhmedkhanov A, Ferrari P, Kato I, Shore RE, Riboli E: Serum carotenoids and breast cancer. Am J Epidemiol (in press).

Toth M, Bernardo MM, Gervasi DC, Soloway PD, Wang Z, Bigg HF, Overall CM, DeClerck YA, Tschesche H, Cher ML, Brown S, Mobashery S and Fridman R: Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergistically with synthetic matrix metalloproteinase (MMP) inhibitors but not with TIMP-4 to enhance the (Membrane type 1)-MMP-dependent activation of pro- MMP-2. J Biol Chem 275:41415-41423, 2000

Trivedi C, Redman B, Flaherty LE, Kucuk O, Du W, Heilbrun LK and Hussain M: Weekly 1-hour infusion of paclitaxel. Clinical feasibility and efficacy in patients with hormone-refractory prostate carcinoma. Cancer 89:431-436, 2000

Tubb JW, XI H, Ge Y, Dutcher JA, Stout MJ, Mohammad RM, Ravindranath Y, Matherly LH: Cystathione-B-synthas cDNA transfection alters the sensitivity and metabolism of cytosine arabinoside in CCRF-CEM leukemia cells in vitro and in vivo: A model of down syndrome and leukemia. Cancer Research, 60:6421-6426, 2000.

Turner JR, Liu L, Fligiel SE, Jaszewski R and Majumdar AP: Aging alters gastric mucosal responses to epidermal growth factor and transforming growth factor-alpha. Am J Physiol Gastrointest Liver Physiol 278:G805-810, 2000

Unger J, Flaherty L, Liu PY, Albain KS, Sondak VK: Gender differences and independent predictors of survival in patients with metastatic melanoma on SWOG trials. Cancer (in press).

Vaishampayan U, Glode M, Du W, Kraft A, Hudes G, Wright J and Hussain M: Phase II study of dolastatin-10 in patients with hormone-refractory metastatic prostate adenocarcinoma. Clin Cancer Res 6:4205-4208, 2000

Vaishampayan U and Hussain M: Adjuvant chemo-/hormonal therapy trials for locally advanced prostate cancer. Curr Oncol Rep 2:402-408, 2000

Varterasian ML, Graff JJ, Severson RK, Weiss L, al-Katib AM and Kalemkerian GP: Non-Hodgkin’s lymphoma: an analysis of the Metropolitan Detroit SEER database. Cancer Invest 18:303-308, 2000

Varterasian ML, Mohammad RM, Shurafa MS, Hulburd K, Pemberton PA, Rodriguez DH, Spadoni V, Eilender DS, Murgo A, Wall N, Dan M and Al-Katib A: Phase II trial of bryostatin 1 in patients with relapsed low-grade non- Hodgkin’s lymphoma and chronic lymphocytic leukemia. Clin Cancer Res 6:825-828, 2000

von Kodolitsch Y, Schwartz AG and Nienaber C: Clinical prediction of acute aortic dissection. Arch Intern Med 160:2977-2982, 2000

Wall NR, Mohammad, RM, Reddy, KB and Al-Katib, AM. Bryostatin 1 induces ubiquitination and proteasome degradation of Bcl-2 in the human acute lymphoblastic leukemia cell line, Reh. Int J Mol Med 5:165-171, 2000

Wang B and Miller FR: Tyrosine phosphorylation of an erbB-2 related p90 protein induced by estrogen in human breast epithelial cells. Int J Oncol 16:1035-1042, 2000

Wankhade S, Yu Y, Weinberg J, Tainsky MA and Kannan P; Characterization of the activation domains of AP-2 family transcription factors. J Biol Chem 275:29701-29708, 2000

Whetstine JR and Matherly LH: The basal promoters for the human reduced folate carrier gene are regulated by a GC-box and a cAMP-response element/AP-1-like element. Basis for tissue-specific gene expression. J Biol Chem 276:6350-6358, 2001

Whitehead RP, Unger JM, Flaherty LE, Eckardt JR, Taylor S, Didolkar MS, Xamlowski W, Sondak VK: Evaluation of CI-980 in patients with disseminated melanoma and no prior chemotherapy: A phase II Southwest Oncology Group Study. Invest. New Drugs (in press).

Wood DP; Orthotopic urinary diversion in women. Urol Clin North Am 27:367-378, 2000

Wu GS, Kim K and el-Deiry WS; KILLER/DR5, a novel DNA-damage inducible death receptor gene, links the p53-tumor suppressor to caspase activation and apoptotic death. Adv Exp Med Biol 465:143-151, 2000

Wu W, Kocarek TA and Runge-Morris M: Sex-dependent regulation by dexamethasone of murine hydroxysteroid sulfotransferase gene expression. Toxicol Lett 119:235-246, 2001

Xiao ZQ, Jaszewski R and Majumdar AP: Aging enhances G(1) phase in the colonic mucosa of rats. Mech Ageing Dev 116:1-14, 2000

Xiao ZQ and Majumdar AP: Induction of transcriptional activity of AP-1 and NF-kappaB in the gastric mucosa during aging. Am J Physiol Gastrointest Liver Physiol 278:G855-865, 2000

Yoo GH, Hocwald E, Korkmaz H, Du W, Logani S, Kelly JK, Sakr W and Jacobs JR: Assessment of carotid artery invasion in patients with head and neck cancer. Laryngoscope 110:386-390, 2000

Yoo GH, Washington J, Piechocki M, Ensley J, Shibuya T, Oda D and Wei WZ: Progression of head and neck cancer in an in vitro model. Arch Otolaryngol Head Neck Surg 126:1313-1318, 2000

Yoo, JY, Wang, XW, Rishi, AK, Lessor, T, Xia, XM, Gustafson, TA and Hamburger, AW. Interaction of the PA2G4 (EBP1) protein with ErbB-3 and regulation of this binding by heregulin. Br J Cancer 82:683-690, 2000

Yoshii T, Inohara H, Takenaka Y, Honjo Y, Akahani S, Nomura T, Raz A and Kubo T: Galectin-3 maintains the transformed phenotype of thyroid papillary carcinoma cells. Int J Oncol 18:787-792, 2001

Zemlicka J: Enantioselectivity of the antiviral effects of nucleoside analogues. Pharmacol Ther 85:251-266, 2000

Zhang Y, Rishi AK, Dawson MI, Tschang R, Farhana L, Boyanapalli M, Reichert U, Shroot B, Van Buren EC and Fontana, JA. S-phase arrest and apoptosis induced in normal mammary epithelial cells by a novel retinoid. Cancer Res 60:2025-2032, 2000

Zhang Y, Mohammad RM, Rishi A, Farhana L, Dawson M, Feng K-C, Leid M, Peterson V, Zhang X-K, Edelstein M, Eilender D, Biggar S, Wall N, Reichert U, Fontana JA: Induction of apoptosis of human B-CLL and B-ALL cells by a novel retinoid and its non-retinoidal analog. Blood (in press).

Zhou Q, Wulfkuhle J, Ouatas T, Fukushima P, Stetler-Stevenson M, Miller FR and Steeg PS: Cyclin D1 overexpression in a model of human breast premalignancy: preferential stimulation of anchorage-independent but not anchorage- dependent growth is associated with increased cdk2 activity. Breast Cancer Res Treat 59:27-39, 2000

Zhang Y, Mohammad RM, Rishi A, Farhana L, Dawson M, Feng K-C, Leid M, Peterson V, Zhang X-K, Edelstein M, Eilender D, Biggar S, Wall N, Reichart U, Fontana JA: Induction of apoptosis of human B-CLL and B-ALL cells by a novel retinoid and its non-retinoidal analog. Blood (in press).

Zonder JA, Shields AF, Zalupski M, Chaplen R, Heilbrun LK, Arlauskas P and Philip PA: A phase II trial of bryostatin 1 in the treatment of metastatic colorectal cancer. Clin Cancer Res 7:38-42, 2001

Books, Chapters and Reviews
Baynes RD, Peters WP. High-Dose Chemotherapy and Stem Cell Transplantation for Breast Cancer. Advanced Therapy for Breast Cancer eds. Singletary SE, Robb GL (eds.). Pp 291-305, Decker Hamilton, 2000.

Baynes RD, Stipanuk MH. Iron: In: MH Stipanuk ed. Biochemical and Physiological Aspects of Human Nutrition. Chapter 31, pp 711-741. Sanders Philadelphia, 2000.

Baynes RD. Interactions of alcohol, iron and hemochromatosis. In: Hemachromatosis. Barton JC and Edwards CQ, Eds. Chapter 45, pp 468-474 Cambridge University Press, Cambridge, 2000.

Baynes RD, Dansey RD, Klein JK, Karanes C, Abella E, Cassells L, Wei WZ, Galy A, Wood G, Peters WP: High dose chemotherapy and peripheral blood progenitor cell transplantation in patients with breast cancer. Invited review. Cancer Investigation 18:440-455-2000.

Baynes RD, Dansey RD, Klein JK, Peters WP: The roles of high dose chemotherapy for adjuvant treatment in high risk breast cancer. Critical Reviews in Oncology/Hematology (in press).

Baynes RD, Dansey RD, Klein JK, Abella E, Hamm C, Campbell M, Galy A, Peters WP: Bone Marrow Transplantation in Breast Cancer. Current Opinion in Oncology (in press).

Baynes RD, Zielinsky I, Dansey RD: Large volume leukapheresis. Cobe Monograph (in press).

Baynes RD, Dansey RD, Klein JK, Karanes D, Abella E, Cassells L, Peters WP: High dose chemotherapy and peripheral blood progenitor cell transplantation for breast cancer. Seminars in Oncology (in press).

Eliason JF: Prolonged in vivo activity of high molecular weight pegylated muteins of granulocyte colony-stimulating activity. In: Methods in molecular biology: Human cytokine protocols. J. Walker (ed.), Humana Press, Totawa, N.J. (in press).

Evelhoch JL: pH and therapy of human cancers. In: Causes and Consequences of acidic pH in tumors – No. 240. Novartis Foundation Symposium, R.J. Gillies. J Wiley & Sons, Ltd., London, U.K. (in press).

Fleshner NE, Kucuk O: Antioxidant dietary supplements: Rationale and current status as chemopreventive agents for prostate cancer. Urology (in press).

George V, Hussain M: Is Early Hormonal Therapy Preferable. In: Advanced Therapy of Prostatic Disease. M Resnick & I. Thompson (eds.). B.C. Decker Inc., Hamilton, Canada, Pg. 332-339, 2000.

Heppner GH, Miller FR, and Shekhar PVM: Nontransgenic models of breast cancer. Breast Cancer Res., 2, 331-334, 2000.

Hryniuk W: The Concept of Dose and Dose Intensity in Breast Cancer: Relevant Clinical Trials in the Conventional Range and Early Trials of High –Dose Therapy. Seminars in Breast Disease 3: 132-143, 2000

Hryniuk W: In the Breast Cancer Fight, it’s the End of the Beginning. Hem/Onc Today 1: 4, June 2000.

Hussain M: Chemotherapy for prostate cancer: Systemic therapy for high risk localized disease. Am Soc Clin Oncol Educational Book, 578-584, 2000.

Kucuk, O. Complementary and Alternative Medicine in the Treatment of Cancer: Current Research and Future Directions. Oncology Issues 15:17-19, 2000.

Matherly LH: Molecular correlates of folate and antifolate membrane transport. In: Progress in nucleic acid research and molecular biology. K. Moldave, ed., Harcourt/Academic Press, San Diego (in press)

Merrill AH, Jr. and Schmelz EM: Sphingolipids: Mechanism-based inhibitors of carcinogenesis produced by animals, plants and other organisms. In: Wildman, R.E.C. (ed.) Handbook of Neutraceuticals and functional foods, pp 377-392, CRC Press, Boca Raton, LO., 2000.

Miller FR: Xenograft models of premalignant human breast disease. Journal of Mammary Gland Biology and Neoplasia 5:41-53, 2000.

Miller FR, Heppner GH: Xenograft models of human breast cancer lines and of the MCF10AT model of premalignant, proliferative breast disease. In: Methods in Mammary Gland Biology and Cancer Research. ed. M.I. and B. Ash, pp. 37-50, Kluwer Academic/Plenum Press, New York, 2000.

Miller FR: Tumor tissue interactions. In: Handbook of Cancer, J. Haier and G.L. Nicolson (eds.), Macmillan Reference Ltd., London (in press).

Mitchell MS: Principles of Biologic Therapy. In: Cancer Treatment, 5^th edition, CM Haskell (ed.), Saunders, Philadelphia (in press)

Mitchell MS: Cancer vaccines come of age. In: Frontiers of biomedicine. AL Goldstein (ed.), Plenum, New York (in press).

Mitchell MS: Allogeneic melanoma vaccines for treatment and prevention of recurrence. In: Biology and treatment of melanoma. FG Haluska (ed.), Kluwer, New York (in press).

Mitchell MS: Biologic agents approved for use. In: Cancer Treatment, 5^th edition, CM Haskell (ed.), Saunders, Philadelphia (in press)

Mohammad, R.M. Beck, F.W.J., Al-Katib, A. Masters J (Ed) Non-Hodgkin’s Lymphoma Cell Lines. In: Human Cell Culture Vol. III. Cancer Cell lines Part3: Leukemias and Lymphomas, In: Masters J.R.W and Palsson, B.O (Eds), Chapter nine, Kluwer Academic Publishers, Boston, USA pp 295-320, 2000.

Mohammad, R.M. Beck, F.W.J.,Wall, N., Al-Katib, A. B-Lymphoid Cell Lines. In: Human Cell Culture Vol. III. Cancer Cell lines Part3: Leukemias and Lymphomas, In: Masters J.R.W and Palsson, B.O (Eds), Chapter three, Kluwer Academic Publishers, Boston, USA pp 61-80, 2000.

Peters WP, Hamm C, Baynes RD. Autologous hematopoietic stem cell transplantation. Cancer Medicine 5^th Edition. Bast J, Kufe D, Pollock, Weichselbaum, Holland, Frei E. (Eds) Pp 890-910. Decker, Hamilton and London (in press).

Schiffer CA, Anderson K. Platelet Transfusion Therapy. ASCO Educational Book, 36^th Annual Meeting ASCO pp 290-298, 2000

Schiffer CA, Larson RA. Acute lymphocytic leukemia in adults. In: Cancer Medicine, 5^th Edition. Holland JF, Frei E, Bast RC, Kufe DW, Pollack RE, Weichslbaum RR, eds. B.C. Decker. pp 1979-1988, 2000.

Schiffer CA, Stone R. Acute myeloid leukemia in adults. In: Cancer Medicine, 5^th Edition. Holland JF, Frei E, Bast RC, Kufe DW, Pollack RE, Weichslbaum RR, eds. B.C. Decker. pp 1947-1970, 2000.

Schiffer CA: Hematopoietic growth factors in patients with leukemia. In: Treatment of Acute Leukemia: New directions for clinical research. Pui CH, ed. Humana Press, Inc. (in press).

Schiffer CA: Acute myeloid leukemia in adults: Where have we been and where do we go from here? Cancer Chemotherapy and Pharmacology (in press)

Schmelz EM: Dietary sphingomyelin and other sphingolipids in health and disease. Invited review. Nutrition Bulletin of The British Nutrition Foundation 25:33-39, 2000.

Schmelz EM: Dietary sphingolipids- Importance in colon cancer and other diseases. Invited review. Dialogue-Newsletter of the New Zealand Milk - Diet and Health News for Professionals 35: 1-4, 2000.

Schwartz AG: Genetic Susceptibility to Lung Cancer. In: Lung Cancer: Principles and Practice. HI Pass, JB Mitchell, D Johnson, A Turissi, J Minna (Eds). JB Lippincott, Philadelphia, PA. 2000.

Schreinemachers DM, Gonzales M, Everson RB, Mendola P, Ray BM, Lewis DR: Hispanic health and nutrition examination survey: 1982-1984: Pesticides in urine and blood. Programs and collection procedures series, National Center for Health Statistics, Hyattsville, MD (in press)

Swerdlow PS. Use of Humans in Biomedical Experimentation, in Scientific Integrity, an Introductory Text with Cases, 2^nd edition, Macrina, FL, ed. ASM Press, Washington DC, 2000.

Wei WZ, Pitchocki M, Pilon S and Kelly, C: “erbB-2 DNA vaccines” Biolab Tech International, January-February p.13-15, 2000.

Wozniak AJ, Kraut MJ: Clinical presentation of lung cancer. In: Lung cancer: Principles and practice. HI Pass (Ed), Lippincott-Raven (in press).

Wu GS, Kim K, El-Deiry WS: KILLER/DR5, a Novel DNA-damage Inducible Death Receptor Gene, Links the p53-tumor Suppressor to Caspase Activation and Apoptotic Death. Adv. Exp. Med. Biol. 465:143-151, 2000.

Yue W, Mor G, Naftolin F, Pauley R, Shim W-S, Harvey H, Santen RJ: Use of aromatase inhibitors in breast carcinoma. In: Endocrine management of breast cancer. J. Robertson, R. Nicholson and D. Hayes (eds.) [in press].

Zemlicka J: Enantioselectivity of the antiviral effects of nucleoside analogues. Pharmacol. Ther., 85: 251-266, 2000.

Abstracts
Abella E, Dansey R, Karanes C, Klein J, Cassells L, Hamm C, AlKatib A, Eilender D, Peters W, Baynes R: STAMP I with amifostine and autologous stem cell rescue is an active combination in advanced NHL: A phase I trial. Proc Am Soc Clin Oncol,19: 61a, 2000.

Adelstein DJ, Adams GL, Li Y, Wagner H, Kish JA, Ensley JF, Schuller DE, Forasatiere AA: A phase III comparison of standard radiation therapy (RT) versus RT plus concurrent cisplatinum (DDP) versus split course RT plus concurrent and 5-Fluorouracil (5FU) in patients with unresectable squmaous cell head and neck cancer (SCHNC) An Intergroup Study. Proc ASCO 19:1624, 2000.

Adelstein DJ, Adams GL, Li Y, Wagner H, Kish JA, Ensley JF, Schuller DE, Forasatiere AA: Int 0126, A phase III comparison of standard radiation therapy (RT) versus RT plus concurrent cisplatinum (DDP) versus split course RT plus concurrent and 5-Fluorouracil (5FU) in patients with unresectable squmaous cell head and neck cancer (SCHNC). 5^th Int Conf H&N Cancer, San Francisco, 2000.

Adsay V, Pierson C, Sarkar F, Zee S, Klimstra D: Immunophenotypic features of intraductal papillary mucinous neoplasms (IPMN) of the pancreas: comparative immuno-histochemical analysis of oncoprotein expression in various components of IPMNs. Annual Meeting of the American Pancreatic Association, October, 2000.

Ahmad I, Al-Katib AM, Beck FWJ, Wall NR, Mohammad RM: Sequential treatment of a resistant CLL-patient with bryo 1 followed by 2-chlorodeoxyadenosine. Proceedings of the American Association for Cancer Research, 41:756, 2000.

Ahunbay EE, Evelhoch JL, Pipe JG: Comparison of Propeller, Spiral And Variable Density Spiral Trajectories by Computer Simulations for Dynamic Contrast Enhanced MRI of Cancer, Workshop on MR in Experimental & Clinical Cancer Research, Geiranger, Norway, August, 2000.

Alangaden GJ, Jamma K, Chandrasekar PH, Karanes C, Klein J, Cassells L, Dansey R, Abella S, Peters W, Baynes R: Clostridium difficile associated diarrhea during hematopoietic stem cell transplantation. Proc Inf Dis Soc Am Abstract #395, 2000.

Alhasan SA, Ensley JF, Sarkar FH: Inhibition of tumor cell invasion is accomplished by down regulation of ERBB-2 expression and MMP secretion in a head and neck squamous cell carcinoma lien (HNSCC). AACR, 2000.

Al-Sukhun A, Aboubakr SE, Girgis RE, Swerdlow PS: Pulmonary Hypertension is Present in 10-30% of Adult Patients with Sickle Cell Disease, ASH Poster, San Francisco, CA, 2000.

Andea A, Philip P, Shields A, Vaitkevicius V, Sarkar F, Adsay V: Is “tail carcinoma” a different entity? A comparative analysis of resected adenocarcinomas from the head and tail of the pancreas. Modern Pathology 13:179:2000.

Andea A, Lonardo F, Adsay V: Microscopically cystic and papillary “large duct-type” invasive adenocarcinoma of the pancreas: a potential mimic of intraductal papillary mucinous and mucinous cystic neoplasms. Modern Pathology 13:179, 2000.

Arias-Mendoza F, Brown TR, Schwarz A, Leach MO, Zakian K, Koutcher JA, Stubbs M, Griffiths JR, Nelson SJ, Heershap A, Glickson JD, Charles HC, Evelhoch JL: Preliminary Results of a Multi-Institutional Trial to Demonstrate Clinical Predictive Value of In Vivo Localized ³¹P MR Spectroscopy Data in Human Non-Hodgkin’s Lymphoma, 8^th Mtg. Int. Soc. Magn. Reson. Med., Denver, CO, April 2000.

Baselga J, Herbst R, LoRusso P, Rischin D, Ranson M, Plummer R, Raymond E, Maddox A, Kaye S.B, Kieback DG, Harris A, Ochs J: Continuous Administration of ZD1839 (Iressa), a Novel Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EFGR-TKI), in Patients with Five Selected: Evidence of Activity and Good Tolerability. Proc. of ASCO 19:686, 2000.

Baynes RD, Dansey RD, Klein JL, Cassells L, Karanes C, Abella E, Hamm C, Parchment R, Baumgart J, Bach F, Peters WP: A phase I trial of escalating Treosulfan in combination with high dose Dacarbazine and Melphalan followed by peripheral blood progenitor cell transplant (PBPCT) in recurrent metastatic ovarian and breast cancer. Proceedings of the European Bone Marrow Transplant Society Meeting, 2000.

Baynes RD, Parchment R, Dansey RD, Klein JL, Karanes C, Hamm C, Abella E, Cassells L, LeVeque G, Baumgart J, Bach F, Peters WP: Phase I Evaluation of High Dose Melphalan, DTIC and Treosulfan (MDT) in Previously Treated Metastatic Breast and Ovarian Cancer. Proc Am Soc Clin Oncol, 19:148a, 585. 2000.

Baynes RD: Anemia in malignancy: Treatment and non-invasive markers of an erythropoietic response. Proceedings of the Chemotherapy Foundation Symposium: Innovative cancer therapy for tomorrow. Bone Marrow Transplantation 26:S33, 2000.

Bentley G, Nassar H, Dan M, Adsay V: Lymphoma of the pancreas: a clinicopathological study of 17 cases. Modern Pathology 13:143, 2000.

Berenson JR, Ravera C, Ma P, Deckert F, Sasaki Y, Saeki T, Takashima S, LoRusso P, Goodin S, Seaman J, Schran H, Zhou H: Population Pharmacokinetics (PK) of Zometa. Proc. ASCO 19:814, 2000.

Bereta M, Bisikirska B, Wong-Staal F, Piao WH, Wainstein JA, Lage AP, Mitchell, MS and Kan-Mitchell J: Nonspecific binding of MHC-tetramers to cultured human T cells. Proc. Amer. Assoc. Immunol. 14:A1229, 2000.

Broome C, Hussain M, Vaughn D: Phase II trial of weekly paclitaxel in patients with previously treated advanced urothelial cancer. Proc Am Soc Clin Oncol 19, abstr. # 1381, 2000.

Chaplen RA, Philip PA, Arlauskas PL: Gemcitabine and cisplatin in the treatment of advanced pancreatic cancer: A case study approach. Proceedings of the Annual Congress of the Oncology Nursing Society, 2000.

Chatterjee S, Severson RK, Weiss LK, Kau TY, Mayes MD: Risk of malignancy in scleroderma. Presented at the 64^th Annual Meeting of the American College of Rheumatology, November, 2000.

Chen, C., and Chen, B: Pore-forming ability of cleaved bcl-2 releases hemoglobin from sheep red blood cells. Proc Am Assoc Cancer Res 41:154a, 2000.

Chu A, Pipe, JG, Evelhoch JL: A Strategy to Decrease Motion Artifacts in Diffusion Weighted Imaging with Multiple-shot Spiral Imaging to Increase Sensitivity, 8^th Mtg. Int. Soc. Magn. Reson. Med., Denver, CO, April, 2000.

Ding BC, Whetstine J, Matherly LH: Inhibition of human reduced folate carrier gene expression by wild type p53, American Association for Cancer Research, 41: 5, 2000.

Chuba P, Hamre MR, Bhambhani K, Severson RK: Causes of death among long term survivors of pediatric CNS tumors. Preceedings of the 36^th Annual Meeting of the American Society of Clinical Oncology 19:19a, 2000.

Dansey RD, Karanes C, Klein JL, Abella E, Cassells L, Hamm C, King R, Peters WP and Baynes RD: Updated results of autologous stem cell transplantation for relapsed/ refractory Hodgkin’s disease using cyclophosphamide, platinum and BCNU (CPB/STAMP1). Proc Am Soc Clin Oncol 19: 64a, 2000.

Djuric Z, Dilaura N, Jenkins I, Mood D, Jen C, Hryniuk W: Weight Loss in Obese Breast Cancer Survivors: Novel Strategies. Breast Cancer Research and Treatment 64: 49, 2000.

Do H, Kau TY, Schwartz, KL, Severson RK, Weiss LK: Comparison of Breast Cancer Cases in the Arab‑American and Caucasian Populations of Metropolitan Detroit. Breast Cancer Res Treat 64:61, 2000.

Dohmen, BM, Wei, R, Grierson, JR, Shields, AF, Reimold, M, Machula, H-J, Bares, R: FLT-speicherung in malignen tumoren: Erste ergebnisse einer pilotstudie. Nuclear Medicine Congress 2000, Munich, March 2000. Nuklearmedizin 39: A44, 2000.

Dohmen BM, Shields AF, Grierson JR, Kuntzsch M, Reimhold M, Sloan A, Machulla H-J, BaresR: [18F]FLT-PET in brain tumors. J Nucl Med. 5:74P, 2000.

Dohmen BM, Kuntzsch M, Grierson JR, Shields AF, Eschmann M, Machula H-J: Ganzkorperverteilung von [F-18]FLT. Medicine Congress 2000, Munich, March 2000., Nuklearmedizin 39: A94, 2000. Nuclear

Duanmu Z and Runge-Morris M: Cloning and dexamethasone regulation of the rat aryl sulfotransferase (SULT1A1) gene. The Toxicologist, 54(1), 215, abstr.1009, 2000.

Eliason JF, Bacsó Z: The DNA of Annexin V Binding Apoptotic Cells is Highly Fragmented. Proc. Am. Assn. Cancer Res. 41: 652-653, 2000.

Evelhoch JL, Brown T, Chenevert T, Clarke L, Daniel B, Degani H, Hylton N, Knopp M, Koutcher J, Lee T-Y, Mayr N, Sullivan D, Taylor J, Tofts P, Weisskoff R: Consensus Recommendation for Acquisition of Dynamic Contrasted-Enhanced MRI Data in Oncology, 8^th Mtg. Int. Soc. Magn. Reson. Med., Denver, CO, April 2000.

Everson, RB, Land SJ , Eliason JF, Klein JL, Baynes RD: Transient resistance to High-dose Chemotherapy, evaluation of use of DNA-damage assays to optimize treatment schedule, Proceedings of the Department of Defense Breast Cancer Research Program Meeting: Era of Hope, Vol. II: 690, 2000.

Feng J, Vaitkevicius V, Shields A, Philip p, Adsay V: Perineural invasion in pancreatic adenocarcinoma. Modern Pathology 13:183, 2000.

Feng J, cheng J, Adsay V: Peri-islet cell invasion by pancreatic ductal adenocarcinoma. Modern Pathology 13:183, 2000.

Fernández-Madrid F, Karvonen RL, Ensley J, Kraut M, Granda JL, and JE Tomkiel: Patients with squamous cell carcinomas of the head and neck produce a different spectrum of antinuclear antibodies than patients with lung squamous cell carcinomas. Center for Molecular Medicine and Genetics and Department of Medicine, Wayne State University. Impact of Biotechnology in Cancer, Geneva, Switzerland, Oct 28-31, 2000.

Ge Y, Huang X, Stout ML, Ravindranath Y, Matherly LH, Taub JW: Increased cytarabine phosphorylation and drug activity in cystathionine beta synthase transfected CCRF-CEM cells is associated with post-transcriptional activation of deoxycytidine kinase. American Association for Cancer Research 41: 803, 2000.

Gifford AJ, Whetstine JR, Bark KS, Kulkarni JS, Taub JW, Haber M, Norris MD, Matherly LH: Mutations in the reduced folate carrier gene (RFC) in childhood acute lymphoblastic leukemia (ALL). American Association for Cancer Research 41: 758, 2000.

Grignon D, Jimenez RE, Hussain M, Tabazcka P, Sakr W, Pontes JE, Wood D: Prognostic significance of Her-2/neu overexpression in muscle invasive urothelial carcinoma of the bladder. Modern Pathology 12(3):100A, 2000.

Guan H P, Ksebati MB, Zemlicka J: Synthetic approaches to unsaturated analogs of nucleosides comprising four- and six-membered rings. 220^th National Meeting of the American Chemical Society, Washington, D.C, Abstract 293., August 20-24, 2000.

Hamm CM, Klein J, Dansey RD, Karanes C, Abella E, Cassells L, Peters W, Baynes RD: CD 34 Selected PBPC Peripheral Blood Progenitor Cell Transplantation (PBPCT) after High-Dose Cyclophosphamide, Cisplatin and Carmustine (CPB) for Breast Cancer Metastatic to Bone or Bone Marrow: Safety and Supportive Care Data. Proc Am Soc Clin Oncol, 19: 57a, 2000.

Hamre MR, Chuba P, Bhambhani K, Yap J, Severson RK: Late deaths in children and adolescents with malignant melanoma of the skin. Presented at the 6^th International Conference on Long‑Term Complications of Treatment of Children and Adolescents for Cancer, Niagra‑on‑the‑Lake, Ontario, Canada, June, 2000.

Hamre MR, Severson RK, Ravidranath Y, Chuba P: Variation in the incidence of low-grade glioma among different ethnic groups. Presented at the 9^th Annual International Symposium on Pediatric Neuro-Oncology, June, 2000.

Hamre MR, Severson RK, Metzger K, Chuba P, Thomas R, Ravindranath Y: Ethnic differences in the incidence of childhood cancer in the United States. Med Pediatr Oncol 35:204, 2000.

Hamre MR, Chuba P, Severson RK, Metzger K, Roarty J, Thomas R, Ravindranath Y: Increased incidence of unilateral and bilateral retinoblastoma among individuals of Hawaiian ethnicity. Med Pediatr Oncol 35:282, 2000.

Hamre MR, Chuba P, Bhambhani K, Ravidranath Y, Thomas R, Severson RK: Comparisons of Hodgkin’s Disease in African Americans and Caucasians. Preceedings of the 36^th Annual Meeting of the American Society of Clinical Oncology 19:19a (abs #67), 2000.

Hasteh F, Klimstra DS, Batts KP, Cheng JD, Adsay V: Lymphoepithelial cysts of the pancreas. Modern Pathology 13:184, 2000.

Hazeldine S T, Polin L, Corbett T H, Horwitz J P: Identification of Centers of Antitumor Activity in XK469, 91^st Annual Meeting of the American Association for Cancer Research, San Francisco, CA., April 1-5, 2000.

Hryniuk W, Peters WP, Ragaz J: Determinants of Outcome in Adjuvant Chemotherapy of Breast Cancer: Dose Intensity Vs. Total Dose Vs. Dose Size. Breast Cancer Research and Treatment 64: 66, (abstr 243) 2000.

Hryniuk W, Hryniuk L, Palen E, Du W, Darga L, Mood D: Using a Risk-Distress Measure to Predict Risk for Treatment Refusal. Breast Cancer Research and Treatment 64: 92, (abstr 368), 2000.

Hu J, Evelhoch JL: High Spatial Resolution ¹H Lipid MRS of Healthy Human Muscles, 8^th Mtg. Int. Soc. Magn. Reson. Med., Denver, CO, April 2000.

Hussain M, Baranowski K, Marsack C, Flaherty L: Weekly paclitaxel, 13-cis-retinoic acid and alpha interferon: A bio-chemotherapy regimen for metastatic renal cell cancer. Proc Am Soc Clin Oncol 19, abstr. #1400, 2000.

Jimenez RE, Grignon D, Vaishampayan U, Hussain M: Analysis of Her-2/neu overexpression in primary and metastatic transitional cell carcinoma of the bladder. Proc Am Soc Clin Oncol 19, abstr.# 1294, 2000.

Kan-Mitchell J, Gruber A, Bereta M and Wong-Staal F: T Cell Stimulatory Capacity of Human Dendritic Cells Transduced by Pseudotyped HIV-1 Vector. Molecular Therapy 1: S8, 2000.

Kan-Mitchell J, Bereta M, Bisikirska B, Blondelle SE, Boggiano C and Wilson DB: Use of a combinatorial nonapeptide library (CPL) in positional scanning format to analyze the degeneracy of the human HLA-2-restricted CTL response to HIV-1 gag77-85. Keystone Symposium AIDS Vaccines in the New Millennium, March 2001.

Kantarjian H, Sawyers C, Hochhaus A, Guilhot F, Schiffer C, Resta D, Druker B: The International STI 571 study group. Phase II study of STI571, a tyrosine kinase inhibitor, in patients with resistant or refractory Philadelphia chromosome positive chronic myeloid leukemia. Am Soc Hem, 2000.

Klein JL, Dansey R, Karanes C, Hamm C, Cassells L, Peters WP, Baynes RD: High-Dose Chemotherapy STAMP 1 and Peripheral Blood Progenitor Cell Transplantation Following Adriamycin Induction Chemotherapy for High-Risk Primary and Locally Advanced Breast Cancer. Proc Am Soc Clin Onc, 19:60a, 234, 2000.

Klein JL, Dansey R, Karanes C, Hamm C, Cassells L, Peters WP, Baynes RD; High-dose chemotherapy STAMP 1 and peripheral blood progenitor cell transplantation following adriamycin induction chemotherapy for high-risk primary and locally advanced breast cancer. Proc Am Soc Clin Oncol,19: 60a, 2000.

Korkmaz H, Nguyen T, Yoo GH, Kucuk O, Ensley J, Hocwald E, Jacobs JR: Distant metastasis in major salivary gland cancers. Otolaryngology Meeting 2000.

Kucuk O, Sarkar F, Bouwman D, Djuric Z, White M, Hryniuk W, Visscher D, Banerjee M: Modulation of Growth and Differentiation in Breast cancer with Soy Isoflavones. Department of Defense Meeting in Atlanta. June 8-12, 2000.

Kucuk O: Prostate Cancer Chemoprevention. MIUC Meeting, New Delhi, India. November 3-5, 2000.

Lamba R, Karanes C, Abella E, Dansey R, Hamm C, Klein J, Baynes R: A long term study of allogeneic bone marrow transplantation in myelodysplastic syndromes. Blood 96; 410a, 2000.

Lash LH, Putt DA, Matherly, LH: Cloning and expression of rat kidney mitochondrial dicarboxylate carrier exhibiting glutathionine transport activity. Toxicol. Sci., 54(1-S), 26, 2000.

Lash LH, Putt DA and Matherly LH: Kinetics and specificity of cloned and expressed rat kidney mitochondrial dicarboxylate carrier exhibiting glutathione transport. J. Am. Soc. Nephrol. 44A-45A, 2000.

Lash LH, Putt DA, Matherly LH: Function of cloned and expressed rat kidney mitochondrial dicarboxylate carrier in glutathione transport. FASEB J 14: A1568, 2000.

Lin H, Zhang XM, Chen C, and Chen B: Mitochondrial cytochrome c release in apoptotic Mo7e human leukemia cells is associated with the cleavage of Bcl-2 into a shortened fragment that is not functional for heterodimerization with Bax. Proc. Am. Assoc. Cancer Res 41:153a, 2000.

LoRusso P, Snads H, Wozniak A, Jasti B, Parchment R, Prakash S. Phase I Clinical Trial of 5-Fluoro-Pyrimidine. Proc. ASCO 19:747, 2000.

Maibenco DC, Weiss LK, White JJ, Schwartz AG, Kau TY, Severson RK: The clinical significance of micro-invasive breast cancer. Presented at the San Antonio Breast Cancer Conference, December, 2000.

Mills KM, Trautschold J, Visscher DW, Nangia-Makker P, Heppner GH, and Shekhar PVM: Tamoxifen suppresses histologic progression to atypia and DCIS in MCF10AT xenografts, a model of early breast cancer. International Association of Pathologists, New Orleans, 2000.

Mitchell MS, Kan-Mitchell J, Minev B, Edman C and Deans RJ: Identification of a novel human melanoma gene, likely the IL-1 receptor antagonist, encoding epitopes recognized by cytolytic T cells. Proc. Amer. Assoc. Immunol.14:A1004, 2000.

Nabha SM, Mohammad RM, Wall N, Dutcher J, Al-Katib A: Combretastatin A-4 prodrug and lymphoma: In vivo antitumor and antiangiogenic activity. Proceedings of the 2000 NCI-EORTC, AACR, Vol. 6 , 4521s (abst #278), 2000.

Nabha SM, Mohammad RM, Wall N, Dutcher J, Pettit GR, Al-Katib A. Combretastatin A-4 prodrug and lymphoma: In vivo antitumor and antiangiogenic activity. Blood, 95: (abstr. #4504), 2000.

Nassar H, Sakr W, Grignon D, Marlow D, Adsay V: Metastatic renal cell carcinoma in the pancreas and periampullary region. Modern Pathology 13:118, 2000.

Nathan W, Mohammad RM, Al-Katib A: Acquired resistance to bryostatin 1 and 2-CdA in a human chronic lymphocytic leukemia cell line is due to modulation of induced IAP expression, bad phosphorylation and bcl:bax protein modulation. Proceedings of the 2000 NCI-EORTC, AACR, Vol. 6 , 4510s (abstr. #221), 2000

Nabha SM, Mohammad RM, Wall NR, Dutcher JA, Pettit GR, Al-Katib AM. Activity of Combretastatin A-4 against B cell leukemia and lymphoma. Proceedings of the American Association for Cancer Research, 41:59 (abstr. #379) 2000.

Nelson DA, Bhattacharyya T, Rizvi S, Edwards H, Swerdlow PS: Patients with Sickle Cell Disease Have Decreased Cortical but Normal Trabecular Bone Density. Am Soc Hem (poster presentation), San Francisco, CA, 2000.

Pauley RJ, SJ Santner and LR Tait: Breast Stromal Fibroblasts and Parenchymal Epithelial Cells: Regulation of Estrogen Synthesis and ER Expression in vitro. DOD Breast Cancer Research Program Meeting, 2000.

Pernick NT, Eldean ZS, Kabbani W, Philip PA, Shields AF, Vaitkevicius VK, Adsay NV: Pancreatic ductal adenocarcinoma in young patients. Modern Pathology, 2001.

Pernick NL, Adsay V: Clinicopathologic analysis of pancreatic adenocarcinoma in African-Americans vs. Caucasians. Modern Pathology 13:189, 2000.

Philip PA, Pernick NL, Vaishampayan U, Simon MS, LoRusso P, Chaplen R, Biernat L, Flaherty LE: Phase II Study of Doxorubicin, Docetaxel, and 5-Fluorouracil (FAT) in Patients with Locally Advanced Breast Cancer. Proc ASCO 19:510, 2000.

Philip PA, Shields AF, Zalupski MM, Foster B, Arlauskas P, Adsay NV, Vaitkevicius VK: Phase II study of gemcitabine (gemzar), 5-fluorouracil and cisplatin in patients with advanced pancreatic cancer. Annual Meeting of the American Pancreatic Association, October, 2000.

Piechocki MP, Pilon S, and Wei W-Z: ERBB-2 (E2) DNA vaccines containing EBV gly-ala repeat (GAr) sequence. Proc. AACR 41: 796, 2000.

Piechocki MP, Pilon S, and Wei W-Z: ERBB-2 with glycine-alanine repeat (GAr) insertion was processed by proteasome and induced tumor rejection . FASEB J. 14: A1003 2000.

Piechocki MP, Pilon S, and Wei W-Z: Development of erbB2 (E2) DNA vaccines. FASEB J. 14: A1003, 2000.

Pilon SA, Piechocki MP, Naishisaka N and Wei WZ: IL-2 or GM-CSF substitute for CD4 T cell help in cyt ERBb-2 DNA vaccination to induce a anti-tumor immunity, Proc. AACR, 41: 796, 2000.

Powell IJ, Sakr W, Weiss L, Haas G, Severson RK: Prostate cancer is biologically more aggressive among African Americans than Caucasian men under age 70 years: hypothesis supported by autopsy and SEER data. Presented at the Annual Meeting of the American Urological Association, April, 2000.

Prakash S, Wozniak A, Foster B, Flaherty L, Shields A, Parchment R, LoRusso P: Phase I Clinical Trial of KRN5500. Proc. of ASCO 19:202a, 788, 2000.

Qureshi MA, Baynes RD, Soubani AO: The value of bronchoscopy in the diagnosis of pulmonary complications following autologous peripheral stem cell transplantation for breast cancer. American Thoracic Society meeting, 2000.

Qureshi MA, Gugnani MK, Swerdlow PS, Girgis RE. Decreased Exhaled Nitric Oxide (NO) In Patients with Sickle Cell Disease. Am Soc Hem (poster), San Francisco, CA, 2000.

Ratner S, Piechocki MP, Galy A: Role of Rho-family GTPase Cdc42 in polarized expression of lymphocyte appendages. Faseb J., 14:A1144, 2000.

Rizzieri DA, Johnson JL, Niedzwiecki D, Lee EJ, Vardiman JW, Powell BL, Schiffer CA, Peterson BA, Canellos GP, Larson RA: Efficacy and toxicity of brief duration, high intensity chemotherapy for small, non-cleaved cell lymphoma/ L-3 acute lymphoblastic leukemia (L3ALL): results of CALGB 9251. Am Soc Hem, 2000.

Serrai H, Loevner LA, Zakian K, Arias-Mendoza F, Rijpkema M, Koutcher JA, Brown TR, Charles HC, Leach MO, Griffiths JR, Nelson SJ, Evelhoch JL, Heershap A, Glickson JD: Monitoring Response of Head & Neck Tumors to Therapy Using In Vivo Localized ³¹P Decoupled MR Spectroscopy : A Preliminary Study, 8^th Mtg. Int. Soc. Magn. Reson. Med., Denver, CO, April 2000.

Shekhar PVM, Nangia-Makker P, Heppner GH, and Visscher DW: Tamoxifen suppresses atypia and DCIS in the MCF10AT xenografts. Proc. AACR, 41, 2000.

Shekhar PVM, Tait L, and Visscher DW: Effects of estrogen and tamoxifen on pre-neoplastic human breast epithelial-endothelial cell interactions and histological progression of MCF10AT xenografts. Era of Hope, (platform presentation) sponsored by Dept. of Defense, June 2000.

Shields AF, Dohme BM, Mangner TJ, Kuntzsch M, Bares R, Stayanoff J, Muzik O, Machulla H.-J: Metabolism of 18F-FLT in patients. J Nucl Med. 5:36P, 2000.

Shields AF, Dohmen BM, Mangner TJ, Lawhorn-Crews J, Machulla H, Muzik O, Bares R: Imaging of thoracic tumors with [18F]FLT. J Nucl Med. 5:74P, 2000.

Sloan AE, Kabrossi B, Barger G, Zamorano L, Baynes R, Wood G: Vaccination of patients with recurrent malignant astrocytoma with autologous tumor and granulocyte macrophage colony stimulating factor (GM-CSF). AANS, 2000.

Song EY, Banerjee M, Du W, Hryniuk W. Diabetes but Not Obesity Is a Prognostic Factor for Disease Free Survival (DFS) in Women with Stage I, II, and III Breast Carcinoma Receiving Tamoxifen. Breast Cancer Research and Treatment 64: 40, (abstr 120), 2000.

Stone RM, Larson RA, Miller K, Moore JO, Amrein PC, Karp JE, Antin JH, Zani VJ, Schiffer CA: A randomized, placebo-controlled, double-blind trial of a loading dose of pegylated recombinant human megakaryocytic growth and development factor (MGDF) as an adjunct to chemotherapy for acute myeloid leukemia (AM). ASCO 19:14, 2000.

Sun H, Collins JM, Mangner TJ, Muzik O, Shields AF: Biodistribution and metabolism of 18F-FAU: A potential chemotherapeutic drug and PET imaging agent. J Nucl Med. 5:264p-265p, 2000.

Toset AW, Everson RB: Measurement of DNA repair in BRCA1 and BRCA2 deficient human cell lines with the Single Cell Gel Electrophoresis (SCGE) assay. Accepted for presentation at the 91^st Annual Meeting of the American Association for Cancer Research, April 1-5, 2000 (in press).

Tranchida P, Hasteh F, Sarkar FH, Tobi M, Fligiel S, Sochacki P, Pietruk T, Adsay V: Poorly differentiated neuroendocrine (small cell) carcinomas of the pancreas: an analysis of 8 examples of a debated entity. Modern Pathology 13:1120, 2000.

Trivedi C, Fontana J, Forman J, Banerjee M, Kucuk O, Sarkar F, Wood D, Hussain M: Modulation of PSA in patients with prostate cancer by soy isoflavones. Proc Am Soc Clin Oncol 19, abstr. #1363, 2000.

Vaishampayan U, Glode M, Crawford D, Kraft A, Hudes G, Wright J, Hussain M: Phase II study of dolastatin-10 in patients with hormone refractory metastatic prostate cancer. Proc Am Assoc Ca Res;41:46, abstr#297, 2000.

Vaishampayan U, Smith DC, Dickow B, Hussain M: Carboplatin, paclitaxel and gemcitabine in advanced urothelial carcinoma: Updated results. Proc Am Soc Clin Oncol 19, abstr.#1343, 2000.

Wall NR, Al-Katib AM, Mohammad RM: Acquired Resistance to Bryostatin 1 and 2-CdA in a Human Chronic Lymphocytic Leukemia Cell Line is Associated with Modulation of IAP Expression, Bad Phosphorylation and Bcl-2:Bax Ratio. 11^th NCI-EORTC-AACR symposium on new drugs in cancer therapy, November 7-10, Amsterdam, Netherlands, 87 (abstr.#221), 2000.

Wall NR, Al-Katib AM, Nabha SM, Mohammad RM: Acquired Resistance to 2-Chloro-Deoxyadenosine in Human Chronic Lymphocytic Leukemia is Associated with Modulation of Inhibitor of Apoptosis Proteins, Bad Phosphorylation and Bcl-2:Bax Ratio. Blood, (abstr. #418) 2000.

Wall NR, Mohammad RM, Nabha SM, Pettit GR, Al-Katib AM: Bryostatin 1 mediates c-IAP1 induction through NF-kB transactivation in the human pre-B ALL cell line, Reh. Proceedings of the American Association for Cancer Research, 41:758 (abstr.#4818) 2000.

Wang R, Ksebati, MS, Drach J C, Zemlicka J: Synthesis and antiviral activity of methylenedifluoro-cyclopropane analogues of nucleosides. XIV International Roundtable: Nucleosides, Nucleotides and Their Biological; Applications, San Francisco, California, Abstract 8, September 10-14, 2000.

Wei WZ, Shibuya T, Yoo G, Ratner S: Foreign peptides as therapeutic agents against solid tumors, Proc. AACR., 41: 114, 2000.

Whetstine,J, Matherly LH: Characterization of the basal transcriptional regions for the human reduced folate carrier promoters. American Association for Cancer Research, 41: 105, 2000.

Wolf W, Presant CA, Colletti PM, Garcia AA, Waluch W, Feldman NR, Evelhoch, J, LoRusso PM, Jackson A, Waterton JC, Barge A: Characterization of tumor blood flow: Reproducibility of Dynamic Contrast Enhanced Magnetic Resonance Imaging (DEMRI) as a Method for Determining Hemodynamic Changes in Human Tumors and Antiangiogenic Therapeutic Effects. Proc. ASCO 2001.

Wood G, Dansey RD, Klein J, Karanes C, Hamm C, Abella E, Cassells L, Skikne BS, Peters WP, Baynes RD: Combined Modality High-Dose Chemotherapy Followed by Adoptive Immunotherapy to Eliminate Minimal Residual Disease in Metastatic Breast Cancer. Proc Am Soc Clin Onc, 19:101a, 390, 2000.

Wozniak A, Kraut M, Kalemkerian G, Kucucu O: Phase II Study of GEMPAC (Gemicitabine and Paclitaxel) in patients (pts) with Advanced Non-Small Cell Lung Cancer (NSCLC). Proc ASCO 19:2015, 2000.

Yap J, Aref A, Nabha S, Wall NR, Mohammad RM, Al-Katib A: Potentiation of radiation effect by bryostatin in chemotherapy-resistant intermediate-grade non-Hodgkin’s lymphoma. Proceedings of the American Association for Cancer Research, 41:371 (#2356) 2000.

Zalupski M, O’Shaughnessy JA, Vukelja SJ, Shields AF, Diener KM, Grove W: Phase II trial of CI-994 in patients with advanced pancreatic cancer. Proceeding of ASCO 19:285a, 2000.

Zemlicka J, Guan H-P, Cheng Y-C, Drach JC, Kern ER: Spriopentane analogues of nucleosides: Chemistry and antiviral activity. 13^th International Conference on Antiviral Research, Baltimore, Maryland, Antiviral Res. 46: A38, Abstract 10, 2000.

Zonder JA, LoRusso P, Heilbrun L, Flaherty LE: Phase II Trial of Weekly Paclitaxel as 2^nd Line Treatment of Metastatic Malignant Melanoma (MMM). Proc. of ASCO 19:2249, 2000.

2000 Report to Investors:
Creating Personal Partnerships

Partnerships for Life


Annual Report
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