Wayne State University, along with McGill University in Canada and the Hong Kong Polytechnic University, have executed an exclusive worldwide license with Viteava Pharmaceutical Inc. for an intellectual property portfolio claiming composition of matter and/or methods of use of novel analogs and derivatives of the green tea flavonoid known as (-)epigallocatechin-3-gallate, or EGCG.This intellectual property resulted from a long-standing collaboration between Q. Ping Dou, Ph.D., professor of oncology, pharmacology and pathology at Wayne State University’s School of Medicine and the Karmanos Cancer Institute, and Tak-Hang Chan, Ph.D., professor emeritus of chemistry at McGill University and the Hong Kong Polytechnic University... More
Ryan Jackson, an undergraduate student working in the laboratory of Dr. Ray Mattingly won an Outstanding Presentation Award at the ABRCMS (Annual Biomedical Research Conference for Minority Students), Nashville, TN, November 2013
Dr. Karin List was an invited speaker at the ASBMB meeting on “Membrane-anchored serine proteases” in Potomac, MD, September 19–22, 2013. She was elected chair for the next meeting in 2015. Congratulations to Gina Zoratti, graduate student in the List lab, for winning the poster award at the same meeting.
David Kessel gave the opening address at the 2013 meeting of the International Photodynamic Association...More
Karin List recently received the Junior Faculty Award from the Wayne State University Academy of Scholars. Only two such Awards are conferred annually- one in the Sciences, and one in Humanities and Social Sciences. The Award recognizes junior faculty members with significant publications or creative achievements that have enabled them to achieve national or international recognition earlier than usual in their careers...[Photo]
Brazilian Biochemistry and Molecular Biology Society honors Dr. Bonnie Sloane. More ...
Dr. Izabela Podgorski, received a Karmanos Strategic Research Initiative Grant for Promising Research entitled “Targeting Tumor-Associated Macrophages with PLX3397 to Enhance Radiotherapy of Prostate Cancer.” More...
The American Society for Photobiology honored Dr. David Kessel with awards that celebrate not just his expansive research career, but the abundant nods to the work itself. He received both the ASP Lifetime Achievement Award and the ASP PhotoCite Award. More....
Dr. Karin List has been awarded a five year R01 grant from the National Cancer Institute to study the role of two proteases in breat cancer development and progession. More...
Departmental faculty members Drs. Sokol Todi and Stanley R. Terlecky recently received grant award notifications related to their work on the cell biology of neuro-degenerative diseases. Dr. Todi received the “Young Investigator in Spinocerebellar Ataxias Award” from the National Ataxia Foundation. Dr. Terlecky received the “Albert and Goldye J. Nelson Endowment Fund Award”, designed to promote “research into the detection, treatment, and cure of Alzheimer’s disease and related disorders”. Congratulations to both investigators.
The graduate program for the Institute of Environmental Health Sciences has merged with the graduate program for Pharmacology. One consequence is that the Pharmacology Department will soon be offering a Concentration in Toxicology as part of its curriculum. (Feb. 2012)
"Congratulations to Aimalie Hardaway (Cancer Biology graduate student in Podgorski lab) for winning 1st place award for her podium presentation at the 2013 Graduate Student Research Day. Her talk titled "Adipocyte-Derived Factors and Bone Degradation: The Role of CXCL1 and CXCL2 in Osteoclastogenesis" is part of her dissertation research."
Several current or former students received awards for their poster presentations at a recent retreat of the Molecular Therapeutics Program at Karmanos. Daniela Buac (Dou lab) and Julie Madden (Boerner lab) won first and second place, respectively, in the graduate student competition. Eric Hales (a graduate of the Wu lab; now in the Matherly lab) won the postdoctoral fellow prize. More than 125 scientists and medical students from the School of Medicine, Karmanos Cancer Institute and Henry Ford Health System participated in the retreat. More...
Congratulations to Pharmacology's Courtney R. Giordano (Terlecky lab) for placing third in Wayne State University's 2013 Graduate Exhibition. He poster presentation entitled "Neuroprotective Effects Against Amyloid-Beta Mediated By A Targeted Antioxidant" includes part of her dissertation research.
Congratulations to Daniel Huereca (Andrade Lab) for being selected a NIDA travel awardee to attend the 2012 Serotonin Club Meeting in Montpellier France. He presented part of dissertation work in a symposium entitled "Frontiers in Serotonin Research: Pioneers and Prodigies".
Dr. John Lazo, President of ASPET, will be the keynote speaker at the 40th Annual Pharmacology Research Colloquium, to be held here at Wayne State on June 7th....[Flyer]
Jenny Rothberg (Sloane lab) was selected as one of the recipients of a 2012 American Association for Cancer Research Minority Scholar in Cancer Research Award.
Dr. Bernadette Victor (Sloane lab) successfully defended her PhD, funded by a DOD Breast Cancer Predoctoral Fellowship. She is undertaking postdoctoral training at St Jude's in Memphis, working in the lab of Dr. Doug Green (Chair of Immunology and Editor-in-Chief of Oncogene).
The Department would like to welcome our four new students who joined this autumn: Kelly McGregor, Wen Qu, Arko Sen and Anne Yang. All are involved in their second research rotation (Feb., 2012).
Congratulations and best wishes to Dr. Kadija Abounit who completed her Ph.D. in August and graduated in December, 2011. She is now doing postdoctoral work with Dr. Jaro Vostal at the FDA in Bethesda, MD.
Cancer Research. Research done by Jenny Rothberg in the Sloane lab, in conjunction with former Wayne State Pharmacology student Jonathan Wojkowiak in the Gillies lab at the Moffitt Cancer Center, has determined that an acidic microenvironment can drive cancer cells to spread. The investigators propose that neutralizing pH would inhibit further invasion, providing a therapeutic opportunity to slow the progression of cancers...[More]
Cell biology and Neuroscience:
Reversible modifications provide an important means for regulating protein function, which is essential for cellular responses. Until recently, phosphorylation has been the major focus of such protein post-translational modification studies. A recent paper by Nick Davis and colleagues reveals another regulated proteome — neuronal proteins modified by the 16-carbon fatty acid palmitate. In a technical tour-de-force, they have detected not only the palmitoylated neuronal proteins identified previously, but several hundred new candidates, including proteins involved in neurotransmitter availability and responsiveness, the growth and retraction of neuronal processes, and synaptic adhesion. More…