Each session will consist of 3 hours of lecture per week for 4 weeks and will be allotted 1 credit. Class meeting times will be arranged with the instructors. An organizational meeting for all courses will be held on Thursday, January 6th at 1:00 PM in the Pharmacology Library (6364 Scott Hall). Contact the listed instructors for course details or R. Yamazaki (ryamazak@med.wayne.edu) for general information.

Human Diseases that Perturb Membrane Transport

A variety of hereditary and autoimmune diseases are the result of a defect(s) in some aspect of membrane transport (secretion and endocytosis).  A better understanding of the molecular basis that underlies all of these diseases will lead to possible therapeutic intervention and better treatments.  For this mini course, students are expected to directly participate in presenting and critiquing journal articles relevant to the topic.  There will be no exam and the grade will be based on their presentation and participation in oral discussion of each article.
 

The Biology of Human Cellular Aging

Stanley Terlecky

Discussion of recent papers relating to aging and the potential roles of active oxygen species and peroxisomes.

This minicourse will cover selected methods used in protein fractionation and the analysis of proteomes. Material providing a theoretical basis for the analysis will be presented. Students will participate in discussions and in mass spectroscopic-based identification of proteins.

This minicourse will explore recent research progress in DNA repair and the role of DNA repair deficiency in human disease development. Individual DNA repair pathways, DNA damage-mediated cell cycle checkpoint regulation, and the consequences of DNA repair defects will be discussed. The minicourse will consist of eight sessions, with each session consisting of an introductory lecture followed by the discussion of a specific assigned paper.
 

Monday 3-5 pm Feb 7 - April 22 for 2 credits

We are currently in an epidemic of obesity and diabetes.  This course will provide an overview of current research topics in obesity/diabetes research along with detailed discussion of high-impact articles published within the last 3 years.  Each session has two components.  In the first part, the student will present a brief lecture that provides  background and significance for a specific topic of interest.  In the second part, the student will lead the discussion 1-2 research reports that addresses specific issues with the topic of interest.    Faculty will lead the first 4 sessions.

The class will be 2 hours per week for 12 weeks. In addition, students will meet with faculty individually prior to their presentation to discuss the presentation and to offer advice.
 

PYC7500/PTH7080/PHC7650/PSL7490
Instructors: Drs. Robert MacKenzie and James Granneman

Continuation of course