PHC 7650 MINICOURSES
SPECIAL COURSE OFFERINGS FOR FALL, 2005
Each session will consist of 3 hours of lecture per week for 4 weeks and will be allotted 1 credit. Class meeting times will be arranged with the instructors. An organizational meeting for all courses will be held on Thursday, September 8th at 1:00 PM in the Pharmacology Library (6364 Scott Hall). Contact the listed instructors for course details or R. Yamazaki (ryamazak@med.wayne.edu) for general information.
Session 1
September 12 - October 7
Session 2
October 10 - November 4
Session 3
November 7 - December 9
Introduction to Protein Sequence, Structure and Function

 Russell Yamazaki

In this course, students will learn how to run BLAST protein searches, download protein sequence information, run and interpret multiple sequence alignments, and view protein 3D structures. This course will  meet on Tue, Thu from 3:30 to 5:00 pm in the Pharmacology library (6464 Scott)

Monoamine Neurons: Substrates for CNS Therapeutics

Kapatos, Bannon, Andrade

Even today, most centrally active drugs work via monoaminergic systems, which constitute a fraction of a percent of all neurons in the CNS. This minicourse will cover the anatomy, neurochemistry, electrophysiology, and molecular biology of central monoamine (i.e. dopamine, norepinephrine and serotonin) neurons. A historical perspective will be complemented by current journal articles. 
Required text: The Biochemical Basis of Neuropharmacology (Cooper, Bloom & Roth)
 

 Cannabinoids

Eugene Schoener

The modern history of cannabinoids is only a generation old but research in the area has progressed with breathtaking speed. This course will cover the multisystemic actions of cannabinoids and the mechanistic underpinnings of those effects. Following an introductory lecture, class members will discuss recent literature in a seminar venue. This class will meet Weds, 2-5 pm, location to be determined.

   
Signal Transduction Targets in Cancer Therapy

Raymond Mattingly

Course content will be an introductory lecture on cancer treatment, followed by student discussion from recent articles and reviews on 3 or 4 new approaches that are currently in development to treat cancer through targeting of signaling pathways.
 

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