| WINTER 2008 |
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PHC 7010
Introduction to Graduate Pharmacology |
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01/28/2008
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Tue, Thu 11:00- 1:00 pm 3125 Scott Hall 4 credits |
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A. Wakade and H.-Y. Wu, course directors |
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| Day |
Date |
Lecture title |
Hr |
Lecturer |
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A. GENERAL PRINCIPLES |
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| Tues |
8-Jan |
Introduction/Receptors, dose-response curves |
1 |
Wakade/Yamazaki |
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Receptor kinetics |
1 |
Yamazaki |
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| Thur |
10-Jan |
Absorption, distribution, elimination, drug
safety |
1 |
Yamazaki |
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Drug metabolism |
1 |
Lash |
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| Tues |
15-Jan |
Pharmacokinetics I |
1 |
Yamazaki |
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Pharmacokinetics II |
1 |
Yamazaki |
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Total Block A |
6 |
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B. AUTONOMIC PHARMACOLOGY |
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| Thur |
17-Jan |
Review of autonomic nervous system; Introduction
to adrenergics |
1 |
Wakade |
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NE synthesis, storage, release |
1 |
Wakade |
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| Tues |
22-Jan |
Adrenergic agonists |
1 |
Wakade |
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Adrenergic antagonists |
1 |
Wakade |
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| Thur |
24-Jan |
Cholinergics: characterization of receptor
signaling I |
1 |
Mattingly |
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Cholinergics: characterization of receptor
signaling II |
1 |
Mattingly |
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| Tues |
29-Jan |
Muscarinic receptors and G proteins |
1 |
Mattingly |
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Nicotinic receptors; anticholinesterases |
1 |
Mattingly |
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Total Block B |
8 |
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| Thur |
31-Jan |
Examination for Blocks A and B (14 hr total) |
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C. CENTRAL NERVOUS SYSTEM |
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| Tues |
5-Feb |
Pharmacogenomics |
1 |
Lash |
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Introduction to CNS agents |
1 |
Kapatos |
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| Thur |
7-Feb |
Sedative hypnotic agents |
1 |
Kapatos |
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Glutamate and GABA systems |
1 |
Kapatos |
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| Tues |
12-Feb |
Epilepsy |
1 |
Bannon |
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Movement disorders Parkinsonism |
1 |
Bannon |
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| Thur |
14-Feb |
Schizophrenia and hallucinogens |
1 |
Andrade |
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Local and general anesthetic agents |
1
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Tisdale
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Tues
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19 Feb
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| Antidepressants/Mood disorders |
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1
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Artalejo
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Nociception and opiates |
1
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Schoener |
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| Thur |
21-Feb |
Drug abuse 1 |
1 |
Schoener |
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Drug abuse 2 |
1 |
Schoener |
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Total Block C |
12 |
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| Tues |
26-Feb |
Examination for Block C (12 hr total) |
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Totals for Blocks A-C (IBS System Biology 2
credit course) |
26 |
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D. CARDIOVASCULAR/RENAL PHARMACOLOGY |
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| Thur |
28-Feb |
Toxicology I |
1 |
Lash |
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Toxicology II |
1 |
Lash |
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| Tues |
4-Mar |
Renal function |
1 |
McCauley |
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Vasodilators |
1 |
McCauley |
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| Thur |
6-Mar |
Hypertension |
1 |
Wakade |
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Cardiac agents
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1 |
Wakade |
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| Tues |
11-Mar |
Spring Break |
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| Thur |
13-Mar |
Spring Break |
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| Tues |
18-Mar |
Cardiac agents Heart failure
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1 |
McCauley |
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Cardiac agents Angina
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1 |
McCauley
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| Thur |
20-Mar |
Coagulation, thrombolytics |
1 |
Yamazaki |
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Lipid lowering agents |
1 |
Yamazaki |
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Total Block D |
10
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E. INFLAMMATION AND ENDOCRINE PHARMACOLOGY |
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| Tues |
25-Mar |
Antiinflammatory agents I |
1 |
McCauley |
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Antiinflammatory agents II |
1 |
McCauley |
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| Thur |
27-Mar |
Histamine/antihistamines |
1 |
Terlecky |
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Thyroid |
1 |
Davis |
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| Tues |
1-Apr |
Adrenal steroids |
1 |
Wu |
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Gonadal steroids |
1 |
Wu |
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| Thur |
3-Apr |
Diabetes and obesity I |
1 |
Davis |
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Diabetes and obesity II |
1 |
Davis |
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Total Block E |
8 |
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F. CHEMOTHERAPY |
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| Tues |
8-Apr |
HIV treatment/Anticancer I |
1 |
Matherly |
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Anticancer agents II |
1 |
Matherly |
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| Thur |
10-Apr |
Anticancer agents III |
1 |
Matherly |
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Anticancer agents IV |
1 |
Matherly |
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| Tues |
15-Apr |
Introduction to chemotherapy: Antimicrobials,
beta-lactams |
1 |
Wu |
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Inhibitors of protein synthesis and DNA function |
1 |
Wu |
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| Thur |
17-Apr |
Antifolates, antifungals, antivirals,
antiparasitics |
1 |
Wu |
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Immunosuppressives |
1 |
Terlecky |
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Total Block F |
8
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Thur
24 Apr
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11:00-2:00 pm Final examination covers
Blocks D-F (26 hrs) |
26 |
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Totals for course |
52
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