WINTER 2007 PHC 7010 Introduction to Graduate Pharmacology (4 credits)
IBS7XXX Pharmacology of the Nervous Systems (2 credits)
Tues, Thurs 11:00-1:00 
3125 Scott Hall
A. Wakade and H.-Y. Wu, course directors
Day Date Lecture title Hr Lecturer
A. GENERAL PRINCIPLES
Tues 9-Jan Introduction to course, reference materials 1
Receptors, dose-response curves 1 Yamazaki
Thur 11-Jan Receptor kinetics 1 Yamazaki
Absorption, distribution, elimination, drug safety 1 Yamazaki
Tues 16-Jan Pharmacokinetics I 1 Yamazaki
Pharmacokinetics II 1 Yamazaki
Thur 18-Jan Drug metabolism 1 Lash
Pharmacogenomics 1 Lash
Total Block A 8
Tues 23-Jan Examination for Block A
B. AUTONOMIC PHARMACOLOGY
Thur 25-Jan Review of physiology of the autonomic nervous system 1 Mattingly
Cholinergics: characterization of receptor signaling 1 Mattingly
Tues 30-Jan Muscarinic receptors and G proteins 1 Mattingly
Nicotinic receptors; anticholinesterases 1 Mattingly
Thur 1-Feb Sympathetic nervous system: characterization of receptor signaling 1 Wakade
Adrenergic agonists 1 Wakade
Tues 6-Feb Adrenergic antagonists 1 Wakade
Adrenergic/cholinergic interactions 1 Wakade
Total Block B 8
Thur 8-Feb Examination for Block B
C. CENTRAL NERVOUS SYSTEM PHARMACOLOGY
Tues 13-Feb Introduction to CNS agents 1 Kapatos
Sedative hypnotic agents 1 Kapatos
Thur 15-Feb Epilepsy 1 Bannon
Motion disorders, Parkinsonism 1 Bannon
Tues 20-Feb Antidepressants and mood stabilizers 1 Artalejo
Schizophrenia and hallucinogens 1 Andrade
Thur 22-Feb Local and general anesthetic agents 1 Tisdale
Nociception and opiates 1 Schoener
Tues 27-Feb Alcohol and Drug abuse I 1 Schoener
Drug abuse II 1 Schoener
Total Block C 10
Thur 1-Mar Examination for Block C
    Totals for Blocks A-C (IBS System Biology 2 credit course) 26  
D. TOXICOLOGY
Tues 6-Mar Toxicology I 1 Lash
Toxicology II 1 Lash
Total Block D 2
E. CARDIOVASCULAR/RENAL PHARMACOLOGY
Thur 8-Mar Renal function 1 McCauley
Vasodilators 1 McCauley
Tues 13-Mar Spring Break
Thur 15-Mar Spring Break
Tues 20-Mar Calcium channel blockers 1 Wakade
Antihypertensive agents 1 Wakade
Thur 22-Mar Cardiac agents I 1 Scarabelli
Cardiac agents II 1 Scarabelli
Tues 27-Mar Coagulation, thrombolytics 1 Yamazaki
Lipid lowering agents 1 Yamazaki
Total Block E 8
F. INFLAMMATION AND ENDOCRINE PHARMACOLOGY
Thur 29-Mar Adrenal steroids 1 Wu
Gonadal steroids 1 Wu
Tues 3-Apr Histamine/antihistamines 1 Terlecky
Thyroid 1 Davis
Thur 5-Apr Antiinflammatory agents I 1 McCauley
Antiinflammatory agents II 1 McCauley
Tues 10-Apr Diabetes and obesity I 1 Davis
Diabetes and obesity II 1 Davis
Total Block F 6
G. CHEMOTHERAPY
Thur 12-Apr Introduction to chemotherapy: Antimicrobials, beta-lactams 1 Wu
Inhibitors of protein synthesis and DNA function 1 Wu
Tues 17-Apr Antifolates, antifungals, antivirals 1 Wu
Immunosuppressants 1 Terlecky
Thur 19-Apr Anticancer agents I 1 Matherly
Anticancer agents II 1 Matherly
Total Block G 6
Final examination covers Blocks D-G (24 hrs)
May 1, 2007 11:00-2:00 pm Room 3125 Scott Hall