D. Chopra
Dharam P. Chopra, Ph.D.
Professor

Institute of Environmental Health Sciences and Pharmacology
2727 Second Avenue, Room 4000
Detroit, MI 48201-2654

Phone: (313) 961-2816
Fax: (313) 577-0082
email: d.chopra@wayne.edu

RESEARCH INTERESTS:

Development of in vitro models of normal human epithelial cells, gene expression in preneoplastic and neoplastic transformation induced by chemical carcinogens.

Select Publications:
Chopra DP, Menard RE, Januszewski J, Mattingly RR.  TNF-alpha-mediated apoptosis in normal human prostate epithelial cells and tumor cell lines. Cancer Lett. 2004 Jan 20;203(2):145-54. PMID: 14732222

Tang S, Bhatia B, Maldonado CJ, Yang P, Newman RA, Liu J, Chandra D, Traag J, Klein RD, Fischer SM, Chopra D, Shen J, Zhau HE, Chung LW, Tang DG. Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells. J Biol Chem. 2002 May 3;277(18):16189-201. PMID: 11839751

Ben-Josef E, Yang SY, Ji TH, Bidart JM, Garde SV, Chopra DP, Porter AT, Tang DG. Hormone-refractory prostate cancer cells express functional follicle-stimulating hormone receptor (FSHR). J Urol. 1999 Mar;161(3):970-6. PMID: 10022736

Tang DG, Li L, Chopra DP, Porter AT. Extended survivability of prostate cancer cells in the absence of trophic factors: increased proliferation, evasion of apoptosis, and the role of apoptosis proteins. Cancer Res. 1998 Aug 1;58(15):3466-79. PMID: 9699682

Chopra DP, Sarkar FH, Grignon DJ, Sakr WA, Mohamed A, Waghray A. Growth of human nondiploid primary prostate tumor epithelial cells in vitro. Cancer Res. 1997 Sep 1;57(17):3688-92. PMID: 9288774

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