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Wayne State University School of Medicine
Otolaryngology-Head and Neck Surgery Department Goals and Objectives

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4201 St Antoine
Detroit, MI 48201
Phone (313) 577-0804

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Grant Funding


Historically, the Department of Otolaryngology has enjoyed relative high levels of outside funding. Presently, grants to various faculty members within the department and the most current, ongoing projects are listed below:

  Investigator  

  Title  

  Number  

Total Project Period  

Current Effort

Current Direct Costs

 

 

 

 

 

 

Church M.

Life-Long Effects of Prenatal Alcohol Exposure

NIAAA, R01 AA09991

09/01/97-08/01/01

50%

$815,255

 

 

 

 

 

 

Church M.

BAEP Screening of Neonates Exposed to Alcohol/Cocaine

NIAAA, R01 AA10941

09/01/97 – 08/01/02

50%

$1,272,131

 

 

 

 

 

 

Church M.

 Supplemental Support – BAEP Screening of Neonates

NIAAA, R01 AA10941-04S1

09/01/00 – 08/01/02

0%

$29,800

 

 

 

 

 

 

Drescher, DG.

Identification of Acoustico-Lateralis Transmitters

R01 DC00156

07/01/94 -06/30/98

10%

$539,154

Drescher, DG.

Identification of Acoustico-Lateralis Transmitters

R01 DC00156  

07/01/98 -06/30/03

20%

$855,763

 

 

 

 

 

 

Drescher, DG

Adenylyl cyclase Signaling in Ear Sensory Epithelia (PI: Drescher, MJ)

R01 DC04076

05/01/99 - 04/30/03

30%

$461,716

 

 

 

 

 

 

Drescher, MJ

Adenylyl cyclase Signaling in Ear Sensory Epithelia

R01 DC04076

05/01/99 - 04/30/03

30%

$461,716

 

 

 

 

 

 

Drescher, MJ.

Identification of Acoustico-Lateralis Transmitters (PI: Drescher, DG)

R01 DC00156

07/01/98 -06/30/03

20%

$855,763

 

 

 

 

 

 

Finlayson, PG

Modulating Auditory Temporal Processing Through Neuronal Ionic Conductances

Deafness Research Foundation

01/01/01 - 12/31/01

75%

$18,173

 

 

 

 

 

 

Finlayson, PG

Second messenger modulation of LSO neuron response

NIH (NIDCD)  
R01 DC04711-01A1 (pending)

12/01/01 - 11/30/06

80%

$750,000

 

 

 

 

 

 

Kaltenbach, J

Life-Long Effects of Prenatal Alcohol Exposure (PI: Church M)

NIAAA, R01 AA09991

09/01/97-08/01/01

25%

$815,255

 

 

 

 

 

 

Kaltenbach, J

Studies of tinnitus in animals

Sepracor, Inc.

04/01/01- 03/31/02

25%

$248,000

 

 

 

 

 

 

Kaltenbach, J

Neural correlates of sound induced tinnitus

Tinnitus Research Consortium

07/01/00-06/30/03

10%

$300,000

 

 

 

 

 

 

Mathog, R.H.

Residency Training in Otolaryngology

NIH T32 DC00026-14

07/01/97 -06/30/02

30%

$622,122

 

 

 

 

 

 

Monsell, E.

Volumetric Change in Acoustic Neuroma

Fund for Henry Ford Hospital

1995-2001

20%

$210,000

 

 

 

 

 

 

Piechocki, M.

DNA Vaccination to over-come peripheral tolerance (PI: W-Z Wei)

US Army Department of Defense

6/01/01-6/01/04

10%

$447,000

 

 

 

 

 

 

Piechocki, M

Development of ERBB-2 Based Breast Cancer Vaccines (PI: W-Z Wei)

NIH:NCI 5 R01 CA76340-03

12/1/97 - 11/30/02

0%

$794,300

 

 

 

 

 

 

Yoo, G

Preventing head & neck tumor progression by restoring cell cycle regulation

American Cancer Society

7/1/99 - 6/30/03

65%

$443,000

 

 

 

 

5%

 

Yoo, G

Antitumor Mechanisms of Docetaxel on Upper Aerodigestive Tract Cells

Aventis Pharmaceuticals

6/01/00- 5/31/03

 

$250,000

 

 

 

 

 

 

Yoo, G.

Phase II Trial of Surgery with Perioperative Ad-p53 Gene Therapy Followed by Chemoradiotherapy for Advanced, Resectable Squamous Cell Carcinoma of the Oral Cavity and Oropharynx. S0011

SWOG & Introgen

5/1/00-12/30/05

5%

 

 

 

 

 

 

 

Yoo, G.

Title: A Phase III, Multi-center, Open Label, Randomized Study to Compare the Overall Survival and Safety of Bi-weekly Intratumoral Administration of RPR/INGN 201 Versus Weekly Methotrexate in 240 Patients with Refractory Squamous Cell Carcinoma of the Head and Neck (SCCHN).

Introgen

12/01/99-12/30/03

 

5%

$53,310

 

 

 

 

 

 

Yoo, G.

A Phase III, Multi-Center, Open-Label, Randomized Study to Compare the Effectiveness and Safety of Intratumoral Administration of RPR/INGN 201 in Combination with Chemotherapy Versus Chemotherapy Alone in 288 Patients with Recurrent Squamous Cell Carcinoma of the Head and Neck

Introgen

03/01/00-12/30/04

5%

$58,310

 

 

 

 

 

 

Zhang, Z.

Neural Correlates of Sound - Induced Tinnitus

Tinnitus Research Consortium

07/01/01 - 06/30/03

65%

$ 300,000

 

 

 

 

 

 

Zhang, Z.

Neural Mechanisms of Tinnitus

University Research Grant Program

05/01/01-04/30/02

5%

$7,000

 

Grants-2000

  • Dennis Drescher, Ph.D., Marian Drescher, Ph.D.-NIH, "Identification of Acoustico-Lateralis Transmitters", $253,835.
  • George Yoo, M.D.-Aventis Pharmaceuticals, "Antitumor Mechanisms of Docetaxel on Upper Aerodigestive Tract Cells", $250,000.
  • James Kaltenbach, Ph.D.-NIH "Central Mechanisms Related to Tinnitus", $330,3888
  • George Yoo, M.D.-Target Genetics Corporation, "EIA Phase II Study", $30,000.

Grants-1999

  • George H. Yoo, M.D.-American Cancer Society, "Preventing Head and Neck Tumor Progression", $443,000.
  • Walter Belenkey, M.D.-The Carls Foundation, $3,000,000.
  • Marian Drescher, Ph.D. Dennis Drescher, Ph.D.-NIH, "Adenylyl Cyclose Signaling in Ear Sensory Epithelia", $733,026.
  • Robert H. Mathog, M.D.-NIH "Research Training in Otolaryngology" $125.916
  • James E. Kaltenbach, Ph.D.-NIDCD (RO1), "Central Mechanisms Related to Tinnitus", $1,874,829.
  • James E. Kaltenbach, Ph.D.-Speracor, "Studies of Tinnitus in Animals", $124,000.

Grants-1998

  • Robert H. Mathog, M.D.-NIH, "Research Training in Otolaryngology", $128,257.
  • George H. Yoo, M.D.-American Cancer Society, "Preventing Head and Neck Tumor Progression", $20,000.
  • George H. Yoo, M.D.-Targeted Genetics, "EIA Lipid Phase II Study", $10,000.
  • Dennis Drescher, Ph.D.-NIH, "Identification of Acoustico-lateralis Transmitters", $327,000.
  • James Kaltenbach, Ph.D.-Pfizer, "The Role of Gaba Receptors in the Modulation of Hearing Thresholds", $185,000.

Grants-1997

  • Robert H. Mathog,M.D.-NIDCD (T32), "Research Training in Otolaryngology", $125,647.
  • Dennis G. Drescher, Ph.D.,-NIH, "Identification of Acoustico-Lateralis Transmitters", $202,291.
  • Wayne S. Quirk, Ph.D., NIH (R29), "Sound-Induced Changes in Cochlear Blood Flow", $109,670.
  • James Kaltenbach, Ph.D.-NIHI (R21), "Central Mechanisms Related to Tinnitus", $142,220.
  • James Kaltenbach, Ph.D.-Pfizer, "Mechanisms of Noise-Induced Tinnitus",  $100,407.
  • George H. Yoo, M.D.-RPR Gencell, "Ad-p53 phase II gene therapy trial", $150,913.
  • George H. Yoo, M.D.-Targeted Genetics, "Phase 1 E1a Gene Therapy Trial", $83,295.
  • Pavan Reddy, M.D.-American Academy of Otolaryngology, "Regulation of Vestibular Blood Flow",  $9,900.
  • Terry Shibuya, M.D.-American Cancer Society, "Assessment of Immunologic Reactivity in HNSCC Patients",  $11,750.

Grants-1996

  • Robert H. Mathog Research Training in Otolaryngology N1H CDRC 2 T32 DC00026-08 $156,439
  • Dennis G. Drescher Principal Investigator-Identification of Accoustico-Lateralis Transmitters N1H 5 RO1 DG00156-16 $194,501
  • Wayne S. Quirk Principal Investigator-Sound-Induced Changes in Cochlear Blood Flow NIH 5 R29 DC01745-4 $115,280
  • James Kaltenbach Principal Investigator-Spontaneous Activity and Neuro Chem American tinnitus Society $30,000
  • Timothy Doerr Regulatory Mechanisms of Vestibular Blood Flow American Otolaryngical Society Research Fund ` $39,621

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