Epilepsy Basic Science Research Group

The faculty at Wayne State University School of Medicine is dedicated to bringing to bear the latest advances in basic research to promote a better understanding and to provide innovative new strategies to treat epilepsy. We strive to combine top national expertise in multiple basic and clinical sciences. Our research efforts span from basic mechanisms of synapse development to positron emission tomography and magnetic resonance imaging of brains of patients with epilepsy. Please see a partial listing of the researchers and their areas of expertise below.

If you would like to help support our research progress, please contact either Dr. Watson or Dr. Chugani below.
 
 

Craig Watson, M.D., Ph.D. 
Director, Adult Epilepsy Program
Professor of Neurology
Correlation of volumetric MRI findings with neuropathological, functional
neuroimaging, and basic neuroscience data
(313) 745-8640
  Harry Chugani, M.D.
Chief of Pedicatric Neurology
Director, Pediatric Epilepsy Program
Director, PET Center
Professor of Pediatrics, Neurology, and Radiology
PET imaging in epilepsy, brain development and plasticity
(313) 993-3840
William Kupsky, M.D.
Associate Professor of Pathology
Neuropathology
(313) 745-8555
DUAL PATHOLOGY: HS + Hippocampal Malformation

Diane Chugani, Ph.D.
Associate Professor of Pediatrics and Radiology
Role of extracellular matrix in neuronal migration disorders in pediatric
epilepsy
(313) 577-6732
James Garbern, M.D., Ph.D.
Assistant Professor of Neurology
Genetic Aspects of Epilepsy
(313) 577-1689
John Kamholz, M.D., Ph.D.
Associate Professor of Neurology
Response of glia and glial membranes in epilepsy
Genetic Aspects of Epilepsy
(313) 577-1689
Karen Krajewski, M.S.,
Assistant Professor of Neurology
Genetic Counselor
Genetic Aspects of Epilepsy
(313) 577-8317
Robert Berman, Ph.D.
Professor of Psychology
Hippocampal slice electrophysiology in patients with temporal lobe epilepsy.
Receptor autoradiography of excitatory amino acids in epilepsy
(313) 577-1705
Husseini Manji, M.D.
Associate Professor of Psychiatry and Behavioral Neurosciences and Pharmacology
Effects of antiepileptic drugs on signal transduction and gene expression
(313) 577-1808
Jeffrey A. Loeb, M.D., Ph.D.
Assistant Professor of Neurology
Basic Molecular Mechanisms in Synapse Formation and Epilepsy
Director, Developmental and Molecular Neurobiology Laboratory
(313) 577-9827
Gregory J. Moore, Ph.D.
Assistant Professor of Psychiatry and Behavioral Neurosciences and Radiology
MRS of metabolic substrates of epilepsy
(313) 577-9090
Paul Walker, Ph.D.
Associate Professor of Anatomy
Transcriptional responses to neural stimulation in epilepsy
(313) 577-5678
Jose Rafols, Ph.D.
Professor of Anatomy
Electron microscopy of aberrant synaptogenesis 
in hippocampal circuits in temporal lobe epilepsy
(313) 577-1049

 

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