Mediastinum Module

These are axial views of the chest with emphasis on the mediastinum as seen by Computed Tomography. The numbered lines on the scout view to the far left correspond to the numbered thumbnail images at the bottom. Click on one of these thumbnail images to show a larger numbered version of the image to the near left.

Click on a number or anatomic structure on the image to the left and the text in this frame will advance to the text corresponding to the structure.

1. Trachea
    The trachea connects the upper respiratory tract to the lower respiratory tract. It is about 9-15 cm in length. It is located in front of the esophagous and behind the thyroid gland in the neck. It is considered to be in the superior and middle mediastinum. It is made up of 16-20 incomplete hyaline cartilaginous rings that are open posteriorly. The trachea bifurcates into the right and left main stem bronchus at a location called the carina, which is located at the level of the sternal angle (T4-T5).  Tracheomalacia is a disorder in infants where the trachea lacks structural support so that the negative airway pressures generated during inspiration causes the trachea to collapse.  This results in a stridorous inspiratory noise.

2.  Esophagus
    The esophagus connects the upper digestive tract to the lower digestive tract. It is 25-30 cm in length. The esophagus is considered to be located in the superior and posterior mediastinum. It has relations to the trachea which is anterior to the esophagus. The thoracic duct sits to the left of the esophagus in the superior mediastinum. The esophagus enters the thorax by penetrating the diaphragm at the esophageal hiatus at the level of T10  The upper half is formed by striated muscles fibers where as the lower half is formed by smooth muscle. Cancers in the upper esophagus are usually squamous whereas cancers of the lower esophagus are adenocarcinomas.
    The blood supply to the esophagus comes from the aorta as well as from the left gastric and inferior phrenic arteries. The esophageal veins empty into the portal venous system.  Esophageal varices are dilated veins of the esophagous seen in conditions of portal hypertension, a condition in which there is obstruction to the blood emptying into the portal system. The most common cause of portal hypertension is cirrhosis of liver in chronic alcoholics. The esophagus is different than other organs of the digestive tract in that it lacks a serosa. This makes the esophagus susceptible to perforation during endoscopy when a scope is placed into the esophagus to visualize it.

3.  Trapezius muscle
    The trapezius is a large back muscle shaped into the shape of trapezoid. It is one of the superficial muscles of the back. It has origins in the spinous processes of C7-T12 vertebrae and inserts to the lateral aspect of the clavicle and scapula. The trapezius attaches the pectoral girdle to the skull and vertebral column. Its actions include elevating, depressing, rotating and retracting the scapula. The trapezius derives its enervation from the spinal accessory nerve (CNXI).

4. Left Clavicle
    The clavicle is a bone that extends horizontally at the base of the neck from the manubrium of the sternum to the acromium of the scapula. Its medial end articulates with the sternum at the sternoclavicular joint. The other end articulates with the scapula through the acromioclavicular joint. It serves to attach the upper limb to the axial skeleton. It also provides attachment for muscles such as the pectoralis major and deltoid muscle. Fractures of the clavicle occur and is found to be concomitant with fractures of the scaphoid in the hand. The mechanism is usually due to falling on an outstretched hand.

4*.  Right Clavicle
    As described above for the Left Clavicle.

5.  Subscapularis Muscle
    This is one of the muscles of the rotator cuff, which is a group of four muscles also including the supraspinatus, infraspinatus, and teres minor. These four muscles are responsible for providing stability for the shoulder joint by holding the head of the humerus in the glenoid cavity of the scapula. The subscapularis sits anterior to the scapula and posterior to the serratus anterior muscle.  The origin of this muscle is located at the subscapular fossa of the scapula. The muscle inserts in the lesser tubercle of the humerus. The action of the muscle is to medially rotation and adduction of the arm. The muscles is enervated by the lower subscapular nerve (C5-C7).

6. Infraspinatus Muscle
    This muscle is also one of the members of the rotator cuff group. It originates from the dorsal aspect of the scapula and inserts into the greater tubercle of the humerus. It also sits inferior to the spine of the scapula. It action is to laterally rotate the arm and also help stabilize the shoulder joint. It is enervated by the subscapular nerve.

7. Supraspinatus Muscle
    This muscle is another member of the rotator cuff. It originates in the supraspinatus fossa of the scapula, which is located above the spine of the scapula. The muscle inserts into the superior aspect of the greater tubercle of the humerus. It is innervated by the subscapular nerve. The actions of the muscle include helping the deltoid muscles to abduct the arm.  As with other rotator cuff muscles, it helps stabilize the shoulder joint.

8. Pectoralis Major Muscle
    The pectoralis muscle is a large muscle that sits in the anterior thorax. It is enclosed by a fascial sheath which laterally forms the axillary fascia. The pectoralis major is superficial to both the pectoralis minor and serratus anterior muscles. It has multiple origins including the medial half of the clavicle and also the anterior surface of the sternum in the first six costal cartilage. It inserts into the greater tubercle of the humerus. Its actions include adducting and medially rotating the humerus. It is innervated by the medial and lateral pectoral nerves.

9.  Pectoralis Minor Muscle
    This muscle is located deep to the pectoralis major muscle. It originates from the costal cartilage of ribs 3-5 and inserts on the coracoid process of the scapula. It is enervated by the medial pectoral nerve. This muscle serves to pull the scapula inferiorly and anteriorly to stabilize it.

10.  Serratus Anterior Muscle
    This muscle is located in the lateral aspect of the thorax. It originates from the external surface of the lateral parts of ribs 1-8. It inserts on the anterior surface of the medial border of the scapula. The muscle sits anterior to the subscapularis muscle. It is enervated by the long thoracic nerve (C5-C7). Known as the boxer's muscle, it is important because it functions to pull the scapula toward the thorax in the forward swing of the arm. Injury to the long thoracic nerve deprives this muscle of its enervation and results in a "winged-scapula". In this condition, the scapula protrudes out in the back when the arm is abducted. There is also a limitation in that the arm cannot be abducted above the horizontal plane.

11.  Latissimus Dorsi Muscle
    This muscle is one of the largest muscles of the body and is appropriately named so in Latin as the widest of the back. This massive muscle covers extends from the lower back and inserts into the crest of the lesser tubercle and intertubercular groove of the humerus.  It originates from the spinous processes of the inferior six thoracic vertebrae and last four ribs. It is enervated by the thoracodorsal nerve (C6-C8). Its actions include extending, abducting, and medially rotating the humerus. It is the muscle used in raising the body in climbing activities. It is located deep to the trapezius muscle. It is also located also inferior to the teres major and teres minor muscles.

12. Erector Spinae Muscles
    This is a group of 3 muscles sitting parallel to the vertebral column laterally on both side of the spinous process of each vertebral process. The three groups of muscles making up the erector spinae are the iliocostalis, longissimus, and spinalis muscles. These muscles extend from the cervical vertebrae down to the tubercles of the 9th to 10th ribs. The function of the muscles are to extend the vertebral column.

13. Left Subclavian Artery
    This artery is the third branch of the ascending aorta. The first branch is the brachiocephalic trunk. The second branch of the aorta is the left common carotid artery. The vessel rises to enter the root of the neck to enter the upper limb. The vessel is related to the anterior scalene muscle anteriorly. This muscle divides the subclavian artery into three parts which are medial, lateral, and deep to the muscle.  The subclavian artery forms important branches which include the internal thoracic artery, vertebral artery, thyrocervical artery, costocervical trunk, and dorsal scapular artery.

13* Distal Subclavian Artery
    The distal portion of the subclavian artery eventually forms the axillary artery after it crosses over the first rib. The axillary artery then becomes the brachial artery after it crosses the inferior border of the teres major muscles.

13a. Right Subclavian Artery

14. Left Common Carotid Artery
     The left common carotid originates directly from the arch of the aorta and ascends in the neck while it is encased in the carotid sheath. It then divides into the external carotid and internal carotid at the superior border of the thyroid cartilage. The carotid sheath also encases the vagus nerve and the internal jugular veins. The vagus nerve is found in a posterior position in the carotid sheath while the internal jugular veins are found lateral to the common carotid artery.

14* Right Common Carotid Artery
    This vessel arises from the brachiocephalic trunk. It is one of the two branches of the brachiocephalic trunk, the other being the right subclavian artery. The carotid body is found at the bifurcation of the internal and external carotid vessels and it serves to measure the pO2 and pCO2 in the arterial blood.

15. Left Internal Jugular Vein
    The internal jugular vein drains the blood supply of the face and the brain. It is the biggest vein in the neck. The vein starts at the jugular foramen as a continuation of the sigmoid sinus. As it travels in the neck, it is encased in the carotid sheath. It is found lateral to the common carotid artery and anterior to the vagus nerve . The vessel joins with the subclavian vein to form the brachiocephalic vein which then enters the superior vena cava. It is possible to cannulate (insert a intravenous line for volume resuscitation) into the internal jugular vein since it is located in a superficial position. At the base of the neck, the vessel can be found medial to the sternocleidomastoid muscle and deep to the medial end of the clavicle.

15* Right Internal Jugular Vein
    See above for left internal jugular vein. Usually larger than the left IJV because of the larger volume of blood entering it from the sigmoid sinus.

16. Scapula
    The scapula and the clavicle are two bones that make up the pectoral girdle. Together these two bones serve to connect the upper limb to the axial skeleton. The scapula sits in the posterior aspect of the thorax. It has a spine on its posterior surface which forms the acromion. The supraspinatus fossa is located above the spine and the infraspinatus fossa is located below the fossa. The acromion wraps around the scapula superiorly and articles with the lateral end of the clavicle at the acromial-clavicular joint. The glenoid fossa is a pocket in the superior and lateral part of the scapula that serves as a surface for articulation for the head of humerus. The coracoid process of scapula is the insertion point for the pectoralis minor muscle.

17.  First Rib
    The first rib is the widest and most curved of the ribs. It is important because it provides an attachment point called the scalene tubercle for the anterior scalene muscle. The subclavian artery, vein, and brachial plexus travels over the first rib to enter the upper limb. The subclavian vein travels anterior to the anterior scalene muscle while the other two structures travel posterior to this muscle.  Moreover, these structures are found posterior to the clavicle. It is has to palpate the first rib because it sits behind the
clavicle.

17*. Second Rib
    This rib is longer and less curved than the first rib.

18. Manubrium of Sternum
    The manubrium of sternum is the broadly-shaped superior part of the sternum that articulates with both the clavicle and the first rib. The superior aspect of the manubrium has a notch on it that is easily palpable.

18*. Body of Sternum
    This part of the sternum is inferior to the manubrium. It articulates with ribs 2-7. It is longer and more narrow than the manubrium. It forms the anterior and medial part of the thorax.

18+.  Xiphoid Process of Sternum
    This is the most inferior part of the sternum. It is the short and pointed end of the sternum. It is cartilaginous up until middle age when it starts to ossify and join with the body of the sternum.

19. Aortic Arch
    The arch of the aorta is found at about the level of the sternal angle. It is a continuation of the ascending aorta which is found in the middle mediastinum. The aorta arches over the root of the left lung and travels posteriorly and to the left to travel to the left of the trachea and esophagous. The aorta then becomes the descending aorta and it travels in the posterior mediastinum. On chest X-rays, the arch of the aorta casts a shadow that is seen and called the aortic knob. An important anatomic relationship here is that the left recurrent laryngeal nerve winds around the arch of the aorta posterior to the ligamentum arteriosum and then travels in between the trachea and esophagous. The ligamentum arteriosum is the embryonic remnant of a vessel that allowed blood to shunt from the pulmonary artery into the aorta. This is because of the high resistance to blood flow in the pulmonary circulation of a fetus.

19*. Ascending Aorta
    The first part of the aorta. The ascending aorta is found in the anterior mediastinum and arches back towards the posterior mediastinum. The ascending aorta is found to the left of the superior vena cava and to the right of the pulmonary trunk. Its first branch is the right brachiocephalic trunk. It arches over the right pulmonary artery. The thymus gland gland is found covering the ascending aorta.

19+. Descending Aorta
    Descending aorta is a continuation of the arch of the aorta. In the thorax, the descending aorta is found to the left of the vertebral column and posterior to the esophagous. It is also to the left of the thoracic duct and anterior to the hemiazygous vein. It pierces the diaphragm at T12 to enter the abdomen. The thoracic duct and azygous vein also accompany the aorta through this hiatus. In the thorax, the aorta gives off nine paired intercostal arteries, esophageal, pericardial, superior phrenic, and bronchial arteries.

20. Azygous Vein
    The name in Latin means unpaired and it well describes the course of this vein. It drains the blood from the abdomen and posterior thorax. It originates at a point posterior to the IVC and the renal vein. It enters into the thorax through the aortic hiatus at T12 and ascends in the thorax posterior to the aorta. It is also posterior to the thoracic duct. The azygous is located to the right of the vertebral column while the hemiazygous system of veins is located to the left.

20*.  Arch of the Azygous
   The azygous vein arches over the root of the right lung and then empties into the superior vena cava.

21. Right Brachiocephalic Vein This vein is formed by the right internal jugular vein and the right subclavian vein. The junction is located behind the medial end of the right clavicle. It is a short vein and is only half the length of the left brachiocephalic vein.

21*. Left Brachiocephalic Vein
    The left brachiocephalic vein is a vein that is formed by the union of the left internal jugular and left subclavian vein. This vein travels to the right and unites with the right brachiocephalic vein behind the manubrium of the sternum. The thymus is located anterior to this vein. The thoracic duct, a vessel that drains lymph from the lower extremities and pelvis, also empties into the left brachiocephalic vein.

22. Superior Vena Cava
    The superior vena cava is an organ that is formed by the junction of the right and left brachiocephalic veins. It is a tributary that drains blood from the head, upper extremity,

23. Thymus Gland
    The thymus is a gland that is located in the anterior part of the superior mediastinum. In children, the thymus is large and is readily recognizable on a chest x-ray. The thymus involutes in adults starting at pubery. In this patient, it is seen on the CT. The organ serves as a role in the development of T lymphocytes in the immune system. The thymus is a site of carcinoma called malignant thymoma.  In a disease called myasthenia gravis, 15% of patients have a malignant thymoma.

24.  Teres Major Muscle
    This muscle sits inferior to the teres minor muscle. It originates from the inferior angle of the scapula and inserts in the intertubercular groove of the humerus. It is enervated by the lower subscapular nerve. Its function is to adduct and medially rotate the arm. The muscle also extends the arm from a flexed position. Although not considered as one of the rotator cuff muscles, the teres major does help in stabilizing the shoulder joint by holding the head of the humerus in the glenoid cavity.

25. Teres Minor Muscle
    This muscle is a fourth member of the rotator group. It originates from the superior part of the lateral border of the scapula and inserts in the greater tubercle of the humerus. Like the teres major, the teres minor is located also below the spine of the scapula. It serves to adduct and medially rotate the arm. It is enervated by the axillary nerve. It sits superior to the teres major muscle.

26. Left Subclavian Vein/Axillary Vein
    This originates from the brachial vein which drains the blood supply from the upper limb. It travels anterior to the anterior scalene muscle but posterior to the clavicle. It also goes over the first rib to join with the internal jugular vein to form the
brachiocephalic vein.

27. Brachiocephalic Artery
    This vessel is the largest branch of the aorta. It gives rise to the right subclavian and right common carotid vessels at a location that is posterior to the right sternoclavicular joint.

28. Inferior Vena Cava
    The inferior vena cava is one of the three veins that drain into the right atrium. The other two are the superior vena cave and the coronary sinus. The IVC is a large vessel that originates at serves as a tributary for the iliac veins, mesenteric veins, and pelvic veins, hepatic, left renal veins.  It forms at the level of the pelvis from the union of the right and left iliac veins. The IVC travels to the right of the abdominal aorta as it ascends into the abdomen. It also goes from a posterior to an anterior position with respect to the aorta. The IVC then pierces the diaphragm at its hiatus at the level of the eighth thoracic vertebra (T8) to enter the thorax.

29. Pulmonary Trunk.
    This is the outlet of the right ventricle. It is a structure that is about 5 cm. in length. It carries deoxygenated blood to the lungs.  The pulmonary trunk is the origin of the right and left pulmonary arteries.

30. Right Pulmonary Artery
    This vessel supplies the lungs with deoxygenated blood that has returned from the body. This vessel has relationships with both the ascending aorta and the superior vena cava. The vessel travels inferior to the arch of the aorta. It is found posterior to the superior vena cava. It is also found posterior to the right pulmonary vein in the right hilum.

30*. Left Pulmonary Artery
    The left pulmonary artery is found anterior to the descending aorta. It is also connected to the arch of the aorta by a connection called the ligamentum arteriosum. This latter structure allows for a way for blood to bypass the high resistance circulation of the lungs and go towards the body. In the fetus and newborn, this connection is patent. The left recurrent laryngeal nerve also loops around the arch of the aorta at this junction to return to the neck.

31. Thoracic Duct
    The thoracic duct is a vessel that drains lymph from the lower extremities, pelvis, abdomen, and left side of thorax. It originates from the cysterna chyli and travels anterior to the vertebral column and swings to the left as it reaches the thorax. It eventually drains into the left brachiocephalic vein.

32. Carina of Trachea
    This is where the trachea bifurcates into the right and left main stem bronchi. The location of this bifurcation is found at about the level of the arch of the aorta or T5. The right main stem bronchus takes a more vertical course at the carina. On x-ray the carina is often visualized. Any distortion of the normal appearance of the carina indicates pathology such as enlarged lymph nodes at the level of the carina.

33. Right Ventricle
    This chamber of the heart receives deoxygenated blood from the right atrium and pumps it towards the lungs where the blood is then enriched with oxygen. This part of the heart is most proximal to the anterior of the thorax. It receives most of its blood supply from the right coronary artery. There is a tricuspid valve that sits in between the right atrium and ventricle. The right ventricle has well developed thick muscles called trabeculae carnae. In a condition called cor pulmonale, the right ventricle enlarges in responses to increase in the resistance of blood flow through the lungs. The enlargement of the right ventricle then causes further deterioration in the cardiac performance and eventually heart failure.

34. Right Atrium
    The right atrium is the first chamber of the heart that receives deoxygenated blood returning from the body. It receives blood from the coronary sinus, superior vena cava, inferior vena cava. It receives its blood supply from the right coronary artery. Atrial septal defects occur when there is a communication between the right and left atria. This allows oxygenated blood from the left atrium to leak over to the right atrium. This causes enlargement of the right atrium due to an increases in pressure in the right atrium. The atrial septal defect is a result of patent foramen ovale in a newborn. This condition can allow emboli originating from the venous side of the body to travel to the arterial side. The condition may, for example, present as a stroke in an adolescent.

35. Left Atrium
    The left atrium receives oxygen-rich blood returning from the lungs through the pulmonary veins. The left atrium then pumps the blood to the left ventricle which then delivers the blood to the body. The left atrium is often a source for formation of thrombi in a condition called mitral stenosis. This condition results when there is a obstruction of blood flow from the left atrium to left ventricle.  This then results in enlargement of the left atrium and wall motion abnormalities in the left atrium. Thrombi may form and cause strokes when they travel to the brain. On a lateral x-ray film of the thorax, an enlarged left atrium is seen as a bulge in the posterior of the heart. The enlarged left atrium can indent the esophagus.

36. Left Ventricle
    The left ventricle is the chamber that is responsible for generating high pressures in order to deliver the oxygenated blood to the body. The chamber has a mitral valve that has two cusps instead of the three cusps on the other three valves of the heart. The mitral valve prevents blood leaking out of the chamber into the left atrium. It has strong muscle called chordae tendonae that hold the aortic valve in place to prevent leakage of blood out of the left ventricle as it is pumping. The left ventricle is supplied by the left anterior descending coronary artery and the left circumflex artery. The left ventricle can enlarge in people with chronic high blood pressure.  On a lateral x-ray film of the thorax, the enlarging left ventricle is seen as a posterior part of the heart that has enlarged. This enlargement is inferior to the left atrium.

37. Right Pulmonary Vein
    This vessel delivers oxygen rich blood from the lungs to the left atrium. It is found inferior to the level of the pulmonary arteries. There is usually a superior and inferior set of pulmonary arteries. The right pulmonary veins are found anterior to the right pulmonary arteries in the right hilum.

37*. Left Pulmonary Vein
    The left pulmonary veins are usually superior to the right pulmonary veins.

38. Interventricular Septum
    This is the muscle between the left and right ventricles.

39. Coronary Sinus
    This is the large vessel that drains the blood supply of the heart and returns it to the right atrium. This vein travels in a groove between the left atrium and left ventricle. It is a tributary for the great, middle, and small cardiac veins.

40. Tricuspid valve
    One of the four valves within the heart, this three cusped valve separates the right atrium from the right ventricle.