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GRANT PROGRAMS

TO BE ELIGIBLE FOR SUPPORT
AN APPLICATION MUST BE RELEVANT TO THE MISSION OF THE
CHILDREN’S RESEARCH CENTER OF MICHIGAN
AND
CHILDREN’S HOSPITAL OF MICHIGAN
Support from the Children's Hospital of Michigan (CHM) Evergreen Endowment, donated by over-two-decades of generous contributions from the Festival of Trees, are used to fund the Children's Research Center of Michigan (CRCM) grant programs.
The funding programs are:
- New Investigator Grant Program (NIGP) - up to $25,000 for one year- is for faculty members who have not been funded by extramural sources such as the NIH, foundations or companies. The requirements and rules pertaining to this program are described below.
- Experienced Investigator Grant Program (EIGP) - up to $50,000 for one year - is for faculty members who currently have or have had extramural support from the NIH, foundations or companies and now wish to develop new areas of research or new approaches towards their current interests. The requirements and rules for this program are also described below.
- Small Grant Program (SGP) – up to $10,000 for one year - the requirements and rules pertaining to this program are detailed below.
- Request for Proposals Grant Program (RFPGP) - from time-to-time, the CRCM may publish Requests for Proposals.
TO BE ELIGIBLE FOR SUPPORT
AN APPLICATION MUST BE RELEVANT TO THE MISSION OF THE CHILDREN’S RESEARCH CENTER OF MICHIGAN AND CHILDREN’S HOSPITAL OF MICHIGAN Support from the Children's Hospital of Michigan (CHM) Evergreen Endowment, donated by over-two-decades of generous contributions from the Festival of Trees, are used to fund the Children's Research Center of Michigan (CRCM) grant programs.
The funding programs are:
1. New Investigator Grant Program (NIGP) - up to $25,000 for one year- is for faculty members who have not been funded by extramural sources such as the NIH, foundations or companies. The requirements and rules pertaining to this program are described below.
2. Experienced Investigator Grant Program (EIGP) - up to $50,000 for one year - is for faculty members who currently have or have had extramural support from the NIH, foundations or companies and now wish to develop new areas of research or new approaches towards their current interests. The requirements and rules for this program are also described below.
3. Small Grant Program (SGP) – up to $10,000 for one year - the requirements and rules pertaining to this program are detailed below.
4. Request for Proposals Grant Program (RFPGP) - from time-to-time, the CRCM may publish Requests for Proposals.
All applicants are encouraged to contact the CRCM Director early in the proposal planning process and are required to use the forms (SF424) provided through the link below. Applicants must follow all of the directions to complete these forms UNLESS otherwise instructed in the text below.
ELIGIBILITY REQUIREMENTS
- Applications for research grants may be submitted by faculty or equivalent staff (defined as individuals who can apply for extramural support for which Wayne State University (WSU) or the Detroit Medical Center (DMC) acts as the fiduciary) from any component or unit of CHM, WSU or the DMC. However, for support by the CRCM, CLEAR AND COMPELLING evidence that the proposed investigations are relevant to the missions of the CRCM and CHM must be presented.
- Applicants from Departments other than Pediatrics or other CHM-departments or divisions MUST ACTIVELY COLLABORATE WITH a co-investigator who is a faculty member in the Department of Pediatrics or whose appointment is directly related to CHM. The co-investigators must be real and active participants in the proposed research.
- Fellows, residents and students cannot apply for support using this mechanism. For these individuals, other funding sources are available. For further information about funding for fellows, residents and students, please contact the CRCM office.
- Grant support may not be used to supplement research projects already being supported by the Public Health Service, NIH, private or public foundations, or from other sources
- A Principal Investigator may only submit one proposal for any application deadline and may have only one active grant award in any funding cycle. If an award is made and activated, the awardee may not submit a new application that could be funded during the year following termination of the last funded application (e.g., a grant terminates on June 30th - the next earliest funding date would be July 1st of the following year. Thus, the earliest submission deadline would be April 1st preceding that July 1 start date).
- Grant support may not be requested for thesis or dissertation research.
- If the application is not funded, it may be resubmitted two additional times (2 revisions). For revisions, the investigator must include an additional page of introduction that explains how the grant application has been changed. Also, the investigator must highlight these changes in the text by using UNDERLINED BOLDFACE ITALICS.
- Racial/ethnic minority individuals, women, and persons with disabilities are encouraged to apply as Principal Investigators.
MECHANISM OF SUPPORT
- The SGP is for preliminary/pilot research efforts. An investigator may request funding up to $10,000 for work to be completed within one year from initiation of the grant award. In order to be considered for this mechanism of support, all other rules contained in the description of Grant Programs apply unless specifically abridged, changed, or excluded. An applicant for the SGP must follow all of the rules and procedures, and use the same forms (the link to forms is shown above on this Webpage) required for the other grant programs. Submission and evaluation of applications to the SGP are on a rolling basis and, therefore, there are no set deadlines. Evaluations of these applications will be made by the CRCM Advisory Committee and outside reviewers who are experts in the area of inquiry.
- The NIGP, which also uses the forms linked to this Webpage, may be requested for one year for direct costs only. No support for indirect costs will be provided and an award is not renewable.
- The EIGP, which also uses the forms linked to this Webpage, provides support for up to one year of research efforts. This program is intended for faculty members who currently have or have had extramural support from the NIH, foundations or companies and now wish to develop new areas of research or new approaches towards their current interests. “New areas of research” or “new approaches” toward current investigatory interests are stringently defined. Because of individual circumstances, potential applicants for this program MUST discuss their research intentions with the CRCM Director BEFORE they apply for funding. Under no circumstances will support be provided for indirect costs nor is an award renewable. Investigators must submit the progress report at least six weeks before the anniversary date for their grant.
- Support can be used for faculty salary, research associates and technicians. However, for faculty salary support, only up to 5% of the applicable NIH maximum for this category can be requested AND the applicant's department must, in writing, agree to pay 2.5% of this amount with the CRCM funding the other 2.5%. Support cannot be used for travel, secretarial services or other services ordinarily provided by CHM, WSU or the DMC. Grant support can be used for small pieces of equipment (not to exceed a total of $5,000), and supplies.
- Under special circumstances, a no-cost extension of up to 1 year, not to exceed the equivalent of 6 month's budget, may be granted prior to expiration of the project period. All requests for an extension MUST be submitted to the CRCM Director at least 3 months before the end of the funding period.
- Rebudgeting between line items in excess of $1000 requires the approval of the CRCM.
RESEARCH OBJECTIVES
- These grant programs provide limited and relatively rapid financial support for research within the program interests of the CRCM and CHM.
- Funding decisions will be based on scientific merit as determined by peer review, with priority given to applications in any of the following four categories:
- Newer, less experienced investigators.
- More experienced investigators, for exploratory studies that represent significant change in research direction.
- More experienced investigators, for testing new methods or techniques.
- Project aligned with NCS research priorities.
- Applications MUST include an introductory paragraph in the research plan section of the application identifying which priority category (1 through 4 above) is relevant and providing explicit justification for its applicability. Failure to provide this introductory paragraph will result in the application being returned to the investigator without comment or consideration.
- If the application does not fall into any of the priority categories, this should be stated.
- While applications may involve a wide variety of biomedical, behavioral, or clinical disciplines, relevance to the mission of the CRCM and CHM must be clear.
- Applications for studies outside these areas will be returned without review.
- Potential applicants with questions concerning acceptability of their proposed work may contact Dr. William D. Lyman, Director, Children’s Research Center of Michigan, 3737 Beaubien, Detroit, MI 48201. Tel. (313) 745-2400, Fax (313) 745-0282, E-mail wlyman@med.wayne.edu.
INCLUSION OF HUMAN SUBJECTS OR LABORATORY ANIMALS IN RESEARCH
All investigators proposing research involving human subjects or laboratory animals must comply with Wayne State University rules, regulations and certifications.
APPLICATION PROCEDURES
- In order to reduce the use of paper, all applications are to be submitted as one (1) paper copy with original signatures and electronically as email attachments or using the latest revision of form PHS SF424 (the link is provided above). APPLICATIONS FOR THE NIGP AND EIGP WILL BE ACCEPTED UNTIL 4:00 PM ON THE DAY OF THE STANDARD DEADLINE - EITHER APRIL 1ST OR OCTOBER 1ST - OF EACH CALENDAR YEAR. Applications must arrive and be logged into the CRCM application database before 4:00PM. Applications that arrive later than this time will be considered for a subsequent grant deadline - at the earliest, 6 months hence. If either April 1 or October 1 is on a Saturday, Sunday or holiday, applications must be received by the CRCM on the last business day before these days. For the SGP and RFPGP, applications will be accepted on a rolling basis (i.e., no deadline).
- The application must be completed according to the instructions accompanying the PHS SF424, with the following exceptions:
The narrative portion of the grant application that describes the research plan (items a-d) may not exceed 10 pages of text. Applications exceeding this length will be returned without review. Appendices may not be used to exceed the page limitation.
An introductory paragraph to the research plan MUST identify which of the three priority categories listed under RESEARCH OBJECTIVES applies and provide an explanation of how that priority category applies.
If the application does not fall into any of the priority areas, this should be stated.
A summary of the grant proposal in lay language MUST accompany the application. The style and content of this summary should be understandable to an individual with a high school education.
Also remember, that any publication or abstract based on work wholly or partially funded by the CRCM must acknowledge CRCM's participation (support, etc).
Each applicant MUST submit the names, complete current and accurate contact information (addresses, telephone numbers, email addresses) of at least 6 potential grant reviewers who are experts in the field of proposed investigation. These individuals should not be DMC/WSU faculty or staff. Failure to comply with this request will result in the return of the application to the investigator without review or comment.
REVIEW CRITERIA
Applications will be evaluated using the following criteria:
1.0 Exceptional
2.0 Outstanding
3.0 Excellent
4.0 Very Good
5.0 Good
6.0 Satisfactory
7.0 Fair
8.0 Marginal
9.0 Poor
View Review Criteria
The basis for these scores will be made by determining the following characteristics of the applications using the associated questions as guidelines:
Significance
Does the proposed research project address scientific and clinical areas and/or topics that promote knowledge in the art and science of medicine in order to improve methods to prevent, cure and treat childhood diseases?
Approach
(a) Are the conceptual and/or clinical framework, design, methods, and analyses adequately developed, well integrated, well reasoned, and appropriate for the aims of the project?
(b) Does the applicant acknowledge potential problem areas and consider alternative tactics?
(c) Is there evidence that the research plan is based on sound investigatory concepts and principles?
(d) Is the approach feasible and appropriate to achieve the stated research goals?
(e) If the proposed program will recruit human study participants, are the recruitment, retention, and follow-up activities adequate to ensure a highly qualified and diverse participant pool?
(f) Is the evaluation plan and timeline adequate for assessing the effectiveness (process and outcome) of the program in achieving its goals and objectives?
Innovation
(a) Is the research program original and innovative?
(b) Does the project challenge existing paradigms or clinical practice; address an innovative hypothesis or critical barrier to progress in the field?
(c) Does the project develop or employ novel concepts, approaches, methodologies, tools, or technologies for this area?
(d) To the best of your knowledge, does this program duplicate, or overlap with existing research?
Investigators
(a) Are the investigators appropriately trained and well suited to carry out this work?
(b) Is the proposed research program appropriate to the experience level of the PI and collaborators?
(c) Does the investigative team bring complementary and integrated expertise to the program (if applicable)?
(d) Is there evidence that an appropriate level of effort will be devoted by the program leadership to ensure the program's objectives?
Environment
(a) Does the scientific environment in which the program will be conducted contribute to the probability of success?
(b) Does the proposed research program benefit from unique features of the scientific environment, subject populations, or employ useful collaborative arrangements?
(c) Is there evidence of appropriate collaboration among participating programs, departments, and institutions?
(d) If multiple sites are participating, is this adequately justified in terms of the research experiences provided?
(e) Are adequate plans provided for coordination and communication between multiple sites (if appropriate)?
AWARD CRITERIA
- Funding is dependent on the availability to the CRCM of adequate financial resources.
- Grant applications must clearly demonstrate that the proposed investigators are directly relevant to the mission of the Children's Research Center of Michigan and Children's Hospital of Michigan.
INQUIRIES
Inquiries are encouraged. The opportunity to clarify any issues or questions from potential applicants is welcome. Direct inquiries regarding programmatic issues to Dr. Lyman at (313) 745-2400 or wlyman@med.wayne.edu.
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