Robert Akins

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Associate Professor Area of interest: Drug Resistance Molecular bases for drug resistance in pathogenic fungi and molecular diagnostics of pathogenic fungi. Ph. D. Ohio State University, 1982 e-mail: rakins@med.wayne.wayne.edu Tel: 313-577-0419

Selected publications:

Arganoza, M.T., Ohrnberger, J., Min, J., Akins, R.A. Suppressor mutants of Neurospora crassa that tolerate allelic differences at single or multiple heterokaryon incompatibility loci. Genetics, 137:731- 742, 1994.

Vazquez, J.A., Arganoza, M.T., Vaishampayan, J.K., and Akins, R.A. In vitro interaction between amphotericin B and azoles in Candida albicans. Antimicrob. Agents Chemother., 40:2511-2516, 1996.

Steffan, P., Vazquez, J.A., Boikov, D., Xu, C., Sobel, J.D., and Akins, R.A. Identification of Candida species by randomly amplified polymorphic DNA (RAPD) fingerprinting. J. Clin. Microbiol., 35:2031-2039, 1997.

Vazquez, J.A., Arganoza, M.T., Boikov, D., Yoon, S., Sobel, J.D., and Akins, R.A. Stable phenotypic resistance of Candida species to amphotericin B is conferred by preexposure to subinhibitory levels of azoles. J. Clin. Microbiol., 36:2690-2695, 1998.

Yoon, S.A., Vazquez, J.A., Steffan, P.E., Sobel, J.D., and Akins, R.A. High frequency, in vitro reversible switching of Candida lusitaniae clinical isolates from amphotericin B-susceptible to resistant. Antimicrob. Agents Chemother., 43:836-845, 1999.