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Through its participation in the Cooperative Multicenter Reproductive Medicine Network, Wayne State University is enrolling women in a national study to determine if the condition of the uterine lining can predict fertility or infertility. Doctors have known for some time that the lining of the uterus changes following ovulation. This has led to the assumption that the lining must meet certain conditions for fertility so the embryo can attach and implant; however, this has not been scientifically proven. This National Institutes of Health study hopes to enroll 880 patients nationally to determine if an endometrial biopsy (sample of the uterine lining) can determine a difference between fertile and infertile women. Doctors are trying to see if defective lining conditions during a woman’s luteal phase (second two weeks of menstruation) could contribute to infertility. “The more we know about the causes of various infertility problems, the more we can do to overcome them,” said Dr. Michael Diamond, who is leading the WSU study site. “We suspect that a defect in the uterine lining could either cause a woman to have difficulty conceiving, or trigger a miscarriage. We will use careful scientific data and analysis to make that determination.” Hutzel Hospital/Wayne State University is currently enrolling two groups of participants. The test group will consist of women who’ve had trouble conceiving a child. The control group will be comprised of women who are not considered infertile. For one to two months, participants will be asked to monitor their menstrual cycle, provide a blood test, urine test, and endometrial biopsy. They will be paid $200 upon completion of the study. For more information about enrolling, please call Nancy Angel at (248) 352-6884 or Karen Collins at (313) 993-8331.
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