Education and Training:
Merrimack College, No. Andover, MA., B.A. 1966
Villanova University, Villanova, PA., M.S. 1972
Boston Univ. School of Medicine, Boston, MA., Ph.D. in Pathology, 1977
Externship in Anatomic and Surgical Pathology, Mallory Institute of Pathology, Boston,
NIH Postdoctoral Fellowship, Lung Biochemistry and Cell Biology,
Boston University School of Medicine 1976-78
Young Pulmonary Investigator, National Heart, Lung and Blood Institute 1978-81

Faculty Appointments:
Research Instructor in Pathology, Boston University School of Medicine, 1977-80
Lecturer in Pathology, Sargent College of Allied Health Sciences, Boston University 1978-81
Assistant Professor of Pathology, Boston University School of Medicine, 1980-81
Assistant Professor of Pathology, Wayne State University School of Medicine, 1981-87
Associate Professor of Pathology, Wayne State University School of Medicine, 1987-Present

Major Interests:
Pulmonary Pathobiology, Inhalation Toxicology, Occupational/Environmental Lung Disease, Ultrastructural Immunocytochemistry, Apoptosis

Representative Publications:

1. Zhong, K., Chua, B.L., and Palmer, K.C. 1 ,25-dihydroxyvitamin D3 metabolism and vitamin D receptor expression in n,ethylnitrosourea-induced pulmonary adenomas. Am. J. Resp. Cell Molec. Biol., 11 :480-486, 1994. [Medline]

2. Wakade, T., Palmer, K.C., McCauley, R., Przywara, D., and Wakade, A. Adenosine-induced apoptosis in embryonic chick sympathetic neurons: a new physiologic role for adenosine. J. Physiol., 488.1:123-138, 1995. [Medline]

3. Wakade, A., Przywara, D., Palmer, K.C., Kulkarni, J., and Wakade, T. Deoxynucleoside induces neuronal apoptosis independent of neurotrophic factors. J. Biol. Chem., 270(30):17986-17992, 1995. [Medline]

4. Kim, H.-R. Choi, Upadhyay, S., Li, G., Palmer, K.C., and Deuel, T.F. Platelet derived growth factor (PDGF) induces apoptosis in growth arrested murine fibroblasts. Proc. Natl. Acad. Sci., 92:9500-9504, 1995. [Medline]

5. Wakade, A.R., Guo, X., Palmer, K.C., Kulkarni, J., Przywara, D.A., and Wakade, T.D. Calcium mobilization and exocytosis in rat chromaffin cells undergoing programmed cell death by 2- deoxyadenosine. J. Neurochemistry, 67:2273-2281, 1996. [Medline]

6. Gulli, L.F., Palmer, K.C., Chen, Y.Q., and Reddy, K.B. EGF induced apoptosis in A431 cells can be reversed by reducing the tyrosine kinase activity. Cell Growth & Differen., 7: 173-178, 1996. [Medline]

7. Shehin-Johnson, S.E., Palmer, K.C., and Hines, R. Identification of tissue-specific Dnasel hypersensitive sites on the rabbit flavin-containing monooxygenase form 2 gene. Drug Metabolism and Disposition, 24:891-898, 1996.[Medline]

8. Raafat, A.M., Murray, M.T., McGuire, T., Defrain, M., Franko, A.P., Zafar, R.S., Palmer, K.C., Diebel, L., and Dulchavsky, S. Calcium blockade reduces renal apoptosis during iachemia reperfusion. Shock, 8(3): 186-192, 1997.[Medline]

9. Kim, H.E., Han, S.J., Liu, H., Palmer , K.C., and Kim, H-R. C. Platelet-derived growth factor (PDGF)-signaling mediates radiation-induced apoptosis in human prostate cancer cells with loss of p53 function. Int. J. Rad. Oncol. Biol. Phys., 39:731-736, 1997.[Medline]

10. Brown, T.R., Zhao, G., Palmer, K.C., and Sundick, R.S. Differential immune responses follow thyriod physical injury and iodine administration in the obese strain chicken. Autoimmunity, 27:1-12, 1998.

11. Yang, Y., Palmer, K.C., Diglio, C., and Schuger, L. Undefferentiated mesenchymal cells isolated from embryonic lungs differentiate in culture into smooth muscle cells. Development, 125:2621-9, 1998.

12. Dong, Z., Nemeth, J.A., Cher, M.L., Palmer, K.C., Bright, R.C., and Fridman, R. Differential Regulation Of Matrix Metalloproteinase-9, Tissue Inhibitor Of Metallaoprotein -1 (Timp-1) And Timp-2 Expression In Co-Cultures Of Prostate Cancer And Stromal Cells. Int. J. Cancer: 93, 507-515, 2001. [Medline]

13. Sohn RL, Murray MT, Swarz K, Nyitray J, Purray P, Franko AP, Palmer KC, Diebel LN, Dulchavsky SA. In-vivo particle mediated delivery of mRNA to mammalian tissues: ballistic and biologic effects. Wound Repair Regen. 2001: Jul-Aug;9 *(4) : 287-96. [Medline]

e-mail: kpalmer@med.wayne.edu