Education and Training:
Wayne State University School of Medicine

Residency Training:
Wayne State University School of Medicine

Fellowship Training:
Veteran's Administration Hospital, Allen Park, Michigan, with Dr. Lawrence Berman

Subspecialty Interest:
Hematopathology

Interests in Pathology:
Defining specific clinical pathologic entities among lymphomas and leukemia using, immunologic, molecular and cytogenetic analyses, and
Laboratory Automation

Publications:

1. Bayerl MG, Rakozy C, Mohamed AN, Vo T, Long M, Eilender D, Palutke M: Blastic Natural Killer Cell Lymphoma/Lukemia: A Report of Seven Cases. American Journal of Clinical Pathology 117; 41.50, 2002. [Medline]

2. Rakozy CK, Mohamed AN, Vo TD, Khatib G, Long PM, Eilander D, Palutke M: CD56+CD4+ Lymphomas and Lukemias are Morphologically and Clinically Diverse. American Journal Of Clinical Pathology 116: 168.176, 2001. [Medline]

3. Mohamed AN, Palutke M, Eisenberg L, Al.Khatib A: Chromosomal analysis of follicular lymphoma with t(14;18), including blastic/blastoid variant. Cancer Genetics & Cytogenetics, Vol 126, pp 45.51. 2001. [Medline]

4. Vaishamapayan UN, Mohamed A, Dugan MC, Bloom RE, Palutke M: Blastic Mantle Cell Lymphoma Associated with 8q24 Abnormality and Hypodiploidy. British Journal of Hematology 115, 66.8, 2001. [Medline]

5. Palutke M and Johnson R. Total Hematology Automation: A modular approach to a completely integrated clinical laboratory. Laboratory Automation News 1, pp8.13, 1996. Invited paper.

6. Mohamed AN, Mahalak SB, Goldfarb SB, Palutke M: Double minute chromosomes contain amplified C myc oncogene sequences in acute myeloid leukemia.[Medline]

7. Palutke M and Johnson R. Achieving Total Hematology Automation: Advance for Administrators of the Laboratory, 4:109.111, 1995.

8. Palutke M, Tabaczka PM & Gingrich D: Expression of CD11c in chronic lymphocytic leukemia. Blood 80:2685, 1992.[Medline]

9. Pandolofi F et al, Palutke M: Clinical course and prognosis of the lymphoproliferative disease of granular lymphocytes. A multicenter study. Cancer 65:341.348, Jan 1990. [Medline]

10. Palutke M, Tabaczka PM, KuKuruga D & Kantor N: A method for measuring lymphocyte proliferation in mixed lymphocyte cultures using a nuclear proliferation antigen, K1.67, and flow cytometry. Amer J Clin Pathol 91:417:.421,1989. [Medline]

11. Palutke M, Eisenberg L, Narang S, Han L, Peeples TC, KuKuruga D & Tabaczka PM: B lymphocytic lymphoma (large Cell) of possible splenic marginal zone origin presenting with prominent splenomegaly and unusual cordal red pulp distribution. Cancer 62:593.600, 1988. [Medline]

12. Palutke M, KuKuruga D & Tabaczka PM: A flow cytometric method for measuring lymphocyte proliferation directly from tissue culture plates using Ki.67 and propidum iodine. J Immunol Methods 105:97.105, 1987. [Medline]

13. Palutke M, KuKuruga D, Roher A & Wolfe D: Flow cytometric purification of Alzheimer’s disease amyloid plaque core protein using thioflavin T. Cytometry 8:494.499, 1987. [Medline]

14. Blaustein JC, Narang S, Palutke M & Ratanatharathom V: Extramedullary (skin) presentation of acute monocytic leukemia resembling cutaneous lymphoma. J Cutaneous Path 14:232.273, 1987. [Medline]

15. Palutke M, Schnitzer B, Narang S, Hyder DM, Parks S, Tabaczka PM & Patch J: Storage and transportation of lymphoid tissue for immunophenotyping. Amer J Clin Pathol 85:494.7, 1986. [Medline]

16. Roher A, Wolfe D, Palutke M & KuKuruga D: Purification, ultra.structure and chemical analysis of Alzheimer’s Disease amyloid plaque core protein. Proc Natl Acad Sci 83:2662.6, 1986. [Medline]

17. Mirchandani IH, Palutke M, Kithier K, Tabaczka PM, Goldfarb S, Eisenberg L & Pak MSY: B cell lymphomas morphologically resembling T cell lymphomas. Cancer 56:1578.83, 1985.[Medline]

18. Mirchandani IH, Palutke M, Kithier K, Tabaczka PM & Suffian J: In vitro neutrophil.erythrocyte rosette formation mediated by a serum factor (lgG). Amer J Hematol 17:79.83, 1984. [Medline]

19. Mirchandani IH, Shah I & Palutke M: True histiocytic lymphoma. A report of four cases. Cancer 52:1901.8, 1983. [Medline]

20. Palutke M, Eisenberg L, Kaplan J, Hussain M, Kithier K, Tabaczka PM, Mirchandani IH & Tenebaum D: Natural Killer and suppressor T cell chronic lymphocytic leukemia. Blood 62:627.34, 1983. [Medline]

21. Mirchandani IH, Palutke M, Dutcher TF & Bishop CR: The value of immunoperoxidase studies in the diagnosis of acute leukemia. Scand J Hematol 30:207.10, 1983.[Medline]

22. Mirchandani IH & Palutke M: Acute megakaryoblastic leukemia. Cancer 50:2866.72, 1983. [Medline]

23. Palutke M, Eisenberg L & Nathan L: Ph.positive T lymphoblastic transformation of chronic granulocytic leukemia in a lymph node. (Letter to the Editor). Lancer II, 1053, 1983. [Medline]

24. Palutke M, Schnitzer B, Mirchandani IH, Tabaczka PM, So K & Carrillo G: Increased numbers of lymphocytes with single class surface immunoglobulins in reactive hyperplasia of lymphoid tissue. Amer J Clin Pathol 78:316.23, 1982. [Medline]

25. Mirchandani IH, Tabaczka PM & Palutke M: Acute monocytic leukemia: A surface marker study. Amer J Hematol 12:139.47, 1982. [Medline]

26. Wylin R, Green M, Palutke M, Khilanani P, Tabaczka PM & Swiderski a: Hairy cell leukemia in 3 siblings: an apparent HLA.linked disease. Cancer 49:538.42, 1982. [Medline]

27. Palutke M, Eisenberg L, Mirchandani IH, Tabaczka PM & Hussain M: Malignant lymphoma of small cleaved lymphocytes of the follicular mantle zone. Blood 59:317.22, 1982.[Medline]

28. Palutke M, Tabaczka PM, Mirchandani IH & Goldfarb S: Lymphocytic lymphoma simulating hairy cell leukemia. A consideration of reliable and unreliable diagnostic features. Cancer 48:2047.55, 1981. [Medline]

29. Palutke M, Schnitzer B, Mirchandani IH, Tabaczka PM, Perrotta A, Eisenberg L, Nathan LE Jr & Gorrin a: Letter to the Editor: T and B cell lymphomas look alike. Amer J Clin Pathol74:360.2, 1980. [Medline]

30. Weise RW, Rozek R & Palutke M: Unusual ribosomal lamellar inclusions in lymphocytes. Micron 11:127.35,1980.

31. Al Saadi A, Palutke M & Kuman GK: Evolution of chromosomal abnormalities in sequential cytogenetic studies of ataxia telangiectasia. Human Genetics 55:23.31 , 1980. [Medline]

32. Palutke M, Tabaczka PM, Weise R W, Axelrod A, Palacas C, Margolis H, Khilanani P, Ratanatharathorn V, Piligian J , Pollard R & Hussain M: T cell lymphomas of large cell type: a variety of malignant lymphomas, "histiocytic" and mixed lymphocytic."histiocytic." Cancer 46:87.101, 1980. [Medline]

33. Palutke M, Tabaczka PM, Varadachari C & Carrillo a: 37 E rosettes in malignant and non.malignant disorders. Brit J Hematol 43:361.7, 1979. [Medline]

34. Palutke M & Tabaczka PM: Functional studies of hairy cell leukemia (leukemic reticuloendotheliosis). Amer J Clin Pathol71:273.80, 1979. [Medline]

35. Palutke M, Weise RW, Tabaczka PM, Varadachari C & Axelrod A: Hairy cells and macrophages: A comparative study. Lab Invest 39:267.80, 1978. [Medline]

36. Palutke M, Varadachari C, Weise RW & Hussain M: Letter to the Editor: Lennert's lymphoma, a T cell neoplasm. Amer J Clin Pathol.Q2:643.6, 1978.

37. Palutke M, Patt DJ, Weise RW, Varadachari C, Wylin R, Bishop CR & Tabaczka PM: T cell leukemia.lymphoma in young adults. Amer J Clin Pathol ~:429.39, 1977.
[Medline]

38. Palutke M, Khilanani P & Weise R: Immunologic and electron.microscopic characteristics of a case of immunoblastic lymph adenopathy. AmerJ Clin Pathol 65:929.41, 1976

39. Palutke M & TranchidaL: T cell lymphoma. Amer J Clin Pathol 21:26.32, 1975.[Medline]

40. Rosenberg JC, Colbourn W, Brennan T, Lyoz K, Palutke M, Stubbs Sand Rosenberg SA: In vitro effect of methylprednisolone on protein synthesis of activated canine thymus derived lymphocytes. Transplant Proc 1:547.56, 1975. [Medline]

41. Palutke M & McDonald J: Monoclonal grammopathies associated with malignant lymphomas. AmerJ Clin Pathol 60:157.63, 1973 [Medline]

42. Reyes M, Palutke M & Lemer MA: Granulocytopenia secondary to carbenicillin therapy. Amer J Med 54:413.8, 1973. [Medline]

43. Palutke M, Kihn R, Perry M, Riddle J, Rector F &. Rosenberg JC: Role of leukocytes and lysosomal enzymes in antibody medicated (hyperacute) renal heterografts. Lab Inves 27:287.95, 1972. [Medline]

44. Palutke M, Kihn R& Rosenberg JC: In vitro studies of hyperacute rejection of xenografts. Europ Surg Res 4:1.9, 1972. [Medline]

45. Perer R, Pultavituma S, Palutke M & Rosenberg JC: A reversible acute reaction following intravenous administration of antilymhocyte globulin. Int Arch Allergy 41:920.31, 1971. [Medline]

Review Articles:

Palutke M & Tabaczka PM: cytochemical and immunoiogical aspects of the Lukemias (as related to FAB classification). Ann Clin Lab Sci 10:269- 75, 1980.

Palutke M: Bone marrow transplantation. By Visitors From Abroad, April 15, 1985. (Published in Chinese).
3 . Books and Chapters

Rosenberg JC, Hawkins E, Mammen E, Palutke M, Riddle J & Rosenberg B: Hyperacute rejection of heterograft: Studies
Of pig to dog renal transplants. In: Coagulation Problems in Transplanted Organs, Von Kaulla KN, ed., Charles C.
Thomas, publisher, 1972, pp 107-42.

Palutke M: Transplantation Immunology: In: Oradwohl's Clinical Laboratory Methods and Diagnosis, Sonnewirth AC &
Jarett L, eds., CV Mosby, publisher, St. Louis, MO, 18th ed., 1980, pp 1279-1306.

Palutke M: Clinical laboratory methods used for the classification of acute leukemia: In: Biology and Therapy of Acute
Leukemia, Baker L, Valeriot F, Ratanatharathorn V, eds., Martinus NiijhoffPublishing, Boston, MA, 1985, pp 43-52.

Palutke M, Schnitzer B., Dresner D, Tabaczka PM, Ratanatharathorn V, Eisenberg L & Tenenbaum D: Comparison of
morphologic features and mitotic rate to cytometrically determined DNA content of poorly differentiated lymphocytic
lymphoma. In: Clinical Cytometry, AndreeffM, ed., Proc Conf Clin Cytometry, Ann NY Acad Sci, New York, 1986, Vol
468, pp 178-94.

4. Case Reports:

Tranchida L, Palutke M, Poulik MD & Prasad AS: Primary acquired sideroblastic anemia preceding monoclonal
gammopathy and malignant lymphoma. Amer J Med 55:559-64, 1973. ,

Prasad S, Tranchida L, Palutke M & Poulik MD: Red cell hypoplasia and monoclonal gammopathy in a patient with
Iymphoproliferative disorder. Amer J Med Sci 271:355-9, 1976.

Ligorski RD, Axelrod AR, Mandell OH, Palutke M & Prasad A: Acute myelomonocytic leukemia in a patient with
macroglobulinemia and malignant lymphoma. Cancer 39: 1156-62, 1977.

Varadachari C, Palutke M, Climie ARW, Weise RW & Chason JL: Immunoblastic sarcoma (histiocytic lymphoma) of
the brain with B cell markers. J Neurosurg 49:887-92, 1978.

Frost H, Shurafa M, Palutke M & Bauer R: Case report: T -lymphocytosis. A diagnostic enigma. Clin Immunol, Sept/Oct,
1980.Simon MR, Salberg DJ, Silva J Jr, Oanji S, Muller F, Desai S & Palutke M: Atypical mycobacterium infection treated
with dialyzable leukocyte extracts: Evidence for antigenic specificity. Clin Immunol Immunopathol 20: 122-8, 1981.

Simon MR, Palutke M, A vigan M & Bradley A: Increased T -cells lacking immunoglobulin Fc receptors and increased spontaneous morphological blast transformation in a patient with phycomycosis. J Clin Immunol 2:59-63, 1982.