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Anwar N.
Mohamed, M.D.
Associate Professor of Pathology
EDUCATION:
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Mosul
Medical College, Mosul, Iraq
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M.D. |
1971
1977
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Medicine
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Duhok
General Hospital, Duhok, Iraq
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Internship |
1977
1978
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Medicine
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Badoosh
Medical Center, Mosul, Iraq
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Residency |
1978
1979
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Medicine
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Cornell
Univ. Medical College, New York, NY
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M.S. |
1981
1983
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Genetics/Cytogenetics
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Memorial
Sloan-Kettering Cancer Center, New York, NY
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Fellowship |
1983
1985
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Neuro-Oncology
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Wayne State University, Detroit, MI
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Res. Assoc. |
1986
1988
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Hematology/Oncology
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FACULTY APPOINTMENTS:
| Associate Professor, Department of Pathology, Wayne State University, Detroit, MI | |
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1997
- present
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1991
- 1997
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Assistant Professor,Department of Pathology, Wayne State University, Detroit, MI |
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1991
- present
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Director of the Cancer Cytogenetics and the Fluorescence in Situ Hybridization Laboratories at Detroit Medical Center |
AWARDS
AND OTHER PROFESSIONAL ACTIVITIES:
Member, Southwest Oncology Group (SWOG), Cytogenetics Study Group
Member, Childrens Oncology Group (COG), Cytogenetics
Basic Scientific Fellowship on the Cancer Chemotherapy Training Grant CA-09207,
1984
National Cancer Institute Postdoctoral Fellow. Biology of Cancer Training Grant,
T-32 CA-09532, 1986-1988
PUBLICATION:
1. Visscher DW, Wallis T, Awussah S, Mohamed A, Crissman JD: Evaluation of c-myc
and chromosome 8 copy number in breast carcinoma using Interphase cytogenetics.
Genes, Chromosomes, Cancer, 18: 1-7, 1997. [Medline]
2. Mohamed AN, Zalupski MM, Ryan JR, Koppitch F, Balcerzak, Kempf R, Wolman
S: Cytogenetic aberrations and DNA ploidy in soft tissue sarcoma: A Southwest
Oncology Group Study. Cancer Genet. Cytogenet 99:45-53, 1997. [Medline]
3. Chopra DP, Sarkar FH, Grignon DJ, Sakr WA, Mohamed AN, Waghrey A: Growth
of human nondiploid primary prostate tumor epithelial cells in vitro. Cancer
Res, 57:3688-3692, 1997. [Medline]
4. Al-Katib A, Smith AR, Kamanda WS, Petit GR, Hamdan M, Mohamed AN, Mohammad
RM: Bryostatin 1 down-regulates mdr1 and potentiates vincristine cytotoxicity
in diffuse large cell lymphoma xenografts Clinical Cancer Res. 4: 1305-1314,
1998,[Medline]
5. Mohammad RM, Dugan MC, Mohamed AN, Almatchy VP, Flake TM, Dergham S, Shields
T, Al-Katib AA, Vaitkevicius VK, Sarkar FH: Establishment of human pancreatic
tumor xenograft Modal: Potential application for preclinical evaluation of novel
therapeutic agents. Pancreas, 16:19-25, 1998. [Medline]
6. Savasan S/ Lorenzana A, Williams JA, Mohamed AN, Ravindranath Y, Zielenska
MI Hamre MI Haas JE, Rector F, Sough H, Abel E: Constitutional balanced translations
in alveolar rhabdomyosarcoma Cancer Genet. Cytogenet. 105: 50-54, 1998. [Medline]
7. Mohamed AN, Varterasian M, Dobin S, McConnell TS, Wolman SR, Willman CL,
Rankin C, Head D, Slovak ML: Trisomy 6 as a primary karyotypic aberration in
hematological disorders. Cancer Genet Cytogenet.106:152-155,1998. [Medline]
8. Savasan S, Fulgenzi LA, Rabah R, Mohamed AN, Ravindranath Y: Generalized
infantile myofibromatosis in a patient with Turner syndrome: A trial of interferon
alpha. J Pediatr l33: 694-696, 1998. [Medline]
9. Mohamed AN, El-Naggar M, Koppitch FC, Bakdounes KM, and Grignon DJ: Chromosome
analysis of six chromophobe renal cell carcinomas. J Urologic. .Pathology 9:
223-231, 1999.
10. Adsay V, Dergharn ST, Koppitch FC, Dugan MC, Mohamed AN, Vaitkevicius V,
Sarkar FH: Utility of fluorescence in situ hybridization in pancreatic ductal
adenocarcinoma. Pancreas, 18:111-116, 1999. [Medline]
11. Virgin JB, Hurley PM, Nahhas F, Bebchuk KG, Mohamed AN, Sakr WA, Bright
R, Cher ML: Isochromosme 8q formation is associated with 8p loss of heterozygosity
in a prostate cancer cell line. Prostate 41:49-57, 1999. [Medline]
12. Mohammad RM, Li Y, Mohamed AN, Pet tit G, Adsay V, Vaitkevicius VK Al-Katib,
Sarkar FH: Clonal preservation of human pancreatic cell line derived from primary
pancreatic adenocarcinoma. Pancreas 19:353-361,
1999. [Medline]
13. Batanian JR, Slovak ML, Mohamed AN, Dobin S, Luthardt FW, Keitges EA, The
South West Oncology Group Cytogenetics Committee: Trisomy 15 is frequently present
as a minor clone in patient with hematological disorders and as a major clone
in patients with AML. Cancer Genet Cytogenet 121:186-189, 2000. [Medline]
14. Slovak ML, Kopecky KJ, Cassileth PA, Harrington DH, Theil K, Mohamed AN,
Paietta E, Willman CL, Head DR, Forman SJ, Appelbaum FR: Karyotypic analysis
predicts outcome of pre-and post-remission therapy in adult acute myeloid leukemia
(AML): a SWOG (S9034)/ECOG (E3489) intergroup study. Blood 96:4075-4083, 2000.
[Medline]
15. Mohamed AN, Palutke M, Eisenberg L, Al-katib A: Chromosomal analyses of
52 cases of follicular lymphma with t(14;18); Including blastic/blastoid variant.
Cancer Genet. Cytogenet 126:45-51, 2001. [Medline]
16. Santner S, Dawson P, Tait L, Soul H, Eliason J, Mohamed AN, Wolman SR, Heppner
GH, Miller FR: Malignant MCF10CA1 cell lines derived from premalignant human
breast epithelial MCF10AT cells. Breast Cancer Res Treat 65:101-110, 2001. [Medline]
17. Mohamed AN, Ebrahim SA, Aatre A, Faisal Qureshi, Suzanne Jacques, Evans
MI: Prenatal diagnosis of a de novo ring chromosome 11.Am J Med Genet 102: 368-371,
2001Vaishampyayan U, Mohamed AN, Dugan MC, Bloom R, Palutke M: Blastoid form
of mantle cell lymphoma associated with Burkitt-like translocation. British
J Hematol 115:66-68, 200118. Rakozy C, Mohamed AN, Vo T,. Khatib G, Long PM,
Eilender D, Palutke M: CD56+/CD4+ Lymphomas and Leukemias are Morphologically
and Clinically Diverse. AM J Clin Pathol. 116: 168-176, 2001.19. Bayerl M, Rakozy
C, Mohamed AN, Vo TD, Long M, Eilender D, Palutke M: Blastic natural killer
cell lymphoma/leukemia: A report of seven cases. I Am J Clinical Pathology 117:41-50,
2002.20. Mohammad R, Abubakr Y, Dan M, Aboukameel A, Chow C, Mohamed A, Hamdy
N, Al-Katib A. Bcl-2 antisense oligonucleotides are effective against systemic
but not central nervous system disease in sever combined immunodeficient mice
bearing human t(14;18) follicular lymphoma. Clinical Cancer Res. 8:1277-1283,
2002 [Medline]
18. Rakozy C, Mohamed AN,
Vo T,. Khatib G, Long PM, Eilender D, Palutke M: CD56+/CD4+ Lymphomas and Leukemias
are Morphologically and Clinically Diverse. AM J Clin Pathol. 116: 168-176,
2001.19. Bayerl M, Rakozy C, Mohamed AN, Vo TD, Long M, Eilender D, Palutke
M: Blastic natural killer cell lymphoma/leukemia: A report of seven cases. I
Am J Clinical Pathology 117:41-50, 2002.20. Mohammad R, Abubakr Y, Dan M, Aboukameel
A, Chow C, Mohamed A, Hamdy N, Al-Katib A. Bcl-2 antisense oligonucleotides
are effective against systemic but not central nervous system disease in sever
combined immunodeficient mice bearing human t(14;18) follicular lymphoma. Clinical
Cancer Res. 8:1277-1283, 2002
[Medline]
19. Bayerl M, Rakozy C, Mohamed AN, Vo TD, Long M, Eilender D, Palutke M: Blastic
natural killer cell lymphoma/leukemia: A report of seven cases. I Am J Clinical
Pathology 117:41-50, 2002.20. Mohammad R, Abubakr Y, Dan M, Aboukameel A, Chow
C, Mohamed A, Hamdy N, Al-Katib A. Bcl-2 antisense oligonucleotides are effective
against systemic but not central nervous system disease in sever combined immunodeficient
mice bearing human t(14;18) follicular lymphoma. Clinical Cancer Res. 8:1277-1283,
2002 [Medline]
20. Mohammad R, Abubakr Y, Dan M, Aboukameel A, Chow C, Mohamed A, Hamdy N,
Al-Katib A. Bcl-2 antisense oligonucleotides are effective against systemic
but not central nervous system disease in sever combined immunodeficient mice
bearing human t(14;18) follicular lymphoma. Clinical Cancer Res. 8:1277-1283,
2002 [Medline]