JOHN D. CRISSMAN, M.D.
Professor of Pathology

Education:
MIT Massachusetts, B.S. 1961
Western Reserve University, Ohio, M.D. 1966

Training:
Internship in Surgery, University of Michigan Hospitals, 1966-1967
Residency in Surgery, Detroit General Hospital, Michigan. 1967-1968
Residency in Pathology, University Hospitals, Ohio, 1970-1974

Hospital and Faculty Appointments:
Assistant Professor of Pathology (1974), Associate Professor of Pathology (1977),
Professor (1981) and Director, Surgical Pathology (1975-81), University of Cincinnati
Professor of Pathology (1981), Director of Anatomic Pathology (1981-1987) Harper-Grace Hospital, Wayne State University School of Medicine
Vice Chairman, Department of Pathology, Henry Ford Hospital, MI (1987-90)
Professor and Chairman, Department of Pathology, Wayne State University,
Pathologist-in-Chief, Detroit Medical Center, Medical Director, Joint Venture Laboratories, Detroit Medical Center, Chief of Pathology, Harper Hospital, 1990-1999
Medical Director of Laboratory Services, Detroit Medical Center, 1990-1999
Associate Dean of Research, 1998-1999
Interim Dean of Medicine, Wayne State University, School of Medicine, 1999-2000
Dean of Medicine, Wayne State University, School of Medicine, 2000-Present

Major interests:
Tumor metastasis, tumor-host interaction, tumor proliferation/differentiation.

Representative Publications:

1. Honn KV, Tsang DG and Crissman JD: Platelets and cancer metastasis: A causal relationship? Cancer and Metastasis Reviews 11:325-351, 1992. Printed in the Netherlands.[Medline]

2. Crissman JD, Drozdowicz S, Johnson C, Kini SR: Fine needle aspiration diagnosis of hyperplastic and neoplastic follicular nodules of the thyroid: A morphometric study. Analyt Quantit Cytol and Histol. 13:321-328, 1991.[Medline]

3. Crissman JD, Zarbo RJ: Quantitation of DNA ploidy in squamous intraepithelial neoplasia of the laryngeal glottis. Arch of Otolaryn Head and Neck Surgery. 117:182-188, 1991.[Medline]

4. Crissman JD, Visscher DW, Kubus J: Image cytophotometric DNA analysis of atypical hyperplasias and intraductal carcinomas of the breast. Arch Pathol Lab Med. 114:1249-1253, 1990.[Medline]

5. Crissman JD, Visscher DW, Sarkar FH: Premalignant lesions of the upper aerodigestive tract: Biomarkers of genetic alterations, proliferation and differentiation. J. Cellular Biochem. Supplement. 17F:192-198, 1993.[Medline]

6. Crissman JD, Sakr WA, Hussein ME, Pontes JE: DNA quantitation of intraepithelial neoplasia and invasive carcinoma of the prostate. The Prostate. 22:155-162, 1993. [Medline]

7. Visscher DW, Sarkar F, Tabaczka P, Crissman J. Clinicopathologic analysis of bcl-2 immunostaining in breast carcinoma. Mod Pathol 9(6):642-646, 1996.

8. Visscher DW, Sarkar FH and Crissman JD. Molecular genetic analysis in the pathologic evaluation of solid tumors: Theory and practice. J Clin Lab Analysis 11:10- 16, 1997.[Medline]

9. Dugan MC, Dergham ST, Kucway R, Singh K, Biernat L, Du W, Vaitkevicius VK, Crissman JD and Sarkar FH. HER-2/neu expression in pancreatic adenocarcinoma: Relation to tumor differentiation and survival. Pancreas 14(3):229-236, 1997.[Medline]

10. Adsay V, Sakr W, Grignon DJ, Crissman J, Sarkar F. Distribution of WAF1 (p21 WAF1) in normal and neoplastic prostaste tissue. J of Urologic Pathology, 9:115-128, 1998.

11. Gnepp DR, Barnes L, Crissman J, Zarbo R. Recommendations for the reporting of larynx specimens containing laryngeal neoplasms. Am J Clin Pathol, 110-137-139, 1998. [Medline]

e-mail: jcrissm@med.wayne.edu