Department of Pediatrics

Division of Pharmacology and Toxicology

Articles, Patents and Intellectual Property

Glibetic M, Parker J, and Aranda JV: Group B streptococcus induction and ibuprofen inhibition of inducible NOS through action of nuclear factor Kappa B, Seminars in Perinatology (in press)

Mauck J, Parker J, Glibetic M, Ricard G, Beaudoin M, Noya F, Aranda JV:  Deregulation of cyclooxygenase and nitric oxide synthase gene expression in the inflammatory cascade triggered by experimental Group B Streptococcal Meningitis in the Newborn Brain and Cerebral Microvessels.  Seminars in Perinatology, Vol 23, No 3, 250-260, 1999.

Heidemann S, Ofenstein J and Sarnaik A: The effect of heat on cytokine production in rat endotoxemia.  Crit Care Med (in press)

Heidemann S, Ofenstein J, and Sarnaik A: Ibuprofen attenuates cardiopulmonary dysfunction by modifying vascular tone in endotoxemia.  Prostaglandin Leukotrienes, Essential Fatty Acids (in press)

Mertineit C, Parker J, Glibetic M, and Aranda JV, Can J:  Nitric oxide, prostaglandins, and impaired cerebral blood flow autoregulation in Group B streptococcus neonatal meningitis, Canadian J of Physiol and Pharmacology (in press, March 2000)

Monin P, Trippenbach T, Bansal R, Aranda JV: GABA function in respiratory control during post-natal development in conscious rabbits. Respiration Physiology (Accepted with revision- 1999).

Ofenstein JP, Dominguez LJ, Sowers JR and Sarnaik AP, Effects of insulin and metformin on glucose metabolism in rat vascular smooth muscle, Metabolism 48, No.11: 1357-1361, 1999.

Ofenstein J, Heidemann S, Wilstermann A, and Sarnaik A, Expression of stress proteins hsp72 & hsp32 in rat spleen cells in response to septic shock, Ann Clin Lab Sci 30, No.1:1-6, 2000.

Abstracts, Letters to the Editor and Articles in Non-Refereed Journals

Aranda JV, Glibetic M, Parker J, and Goodyer P, Expression of cyclo-oxygenase and nitric oxide in human fetal kidney. Platform presentation, SPR, San Francisco, May 1999.

Glibetic M, Parker J, Beharry K, and Aranda JV, Molecular action of ibuprofen in neonatal meningitis. Platform presentation. SPR, San Francisco, May 1999.

Glibetic M, Parker J, Papageorgiou A, and Aranda JV, GBS induction of inducible NOS through activation of NF KappaB. Platform presentation, SPR, San Francisco, May 1999.

Glibetic M, Parker J, and Aranda JV, Group B streptococcus induction and ibuprofen inhibition of inducible NOS through action of nuclear factor Kappa B. Presentation at International Perinatal Collegium, Switzerland, July 1999.

Glibetic M, Ofenstein JP, Marinska, V, Action of Group B streptococcus (GBS) on human lung epithelial cells: involvement of inducible nitric oxide synthase (INOS), interleukin-8 and nuclear factor Kappa B. Accepted for presentation, SPR Boston, May 2000.

Glibetic M, Ofenstein J, Parker J, Marinska V and Aranda JV,Early action of Group B streptococcus (GBS) on human lung epithelial cells: involvement of inducible nitric oxide synthase (INOS), interleukin-8 (il-8) and nuclear factor Kappa B (NFKB). Soc Ped Res. Boston, MA May 2000.

Ofenstein JP and Wilstermann A, Heat induced HSP 72 does not protect rats from endotoxin by decreasing nitric oxide synthesis. Crit Care Med Symposium, San Francisco, CA February 1999.

Ofenstein JP, Heidemann SM, Wilstermann A, and Sarnaik AP, Endotoxemic rats have impaired HSP 70 induction. Ann Clin Lab Sci  Platform presentation, Columbus, Ohio May 1999.

Ofenstein J and Wilstermann A, Early protection from endotoxin by heat induced HSP 72 in rats is not mediated by decreasing nitric oxide synthesis. Soc Ped Res. Boston, May 2000.

Prescilla R, Marinska V, Glibetic M, Parker J, and Aranda JV, Ibuprofen and rofecoxib suppress GBS induced cyclooxigenase-2 gene expression in human lung epithelial cells. Soc Ped Res. Boston, May 2000.

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