Department of Internal Medicine

Division of Infectious Diseases

Articles, Patents and Intellectual Property

Vakulenko SB, Taibi-Tronche P, Toth M, Massova I, Lerner SA, Mobashery S.  Effects on substrate profile by mutational substitutions at positions 164 and 179 of the class A TEMpUC19  (-lactamase from Escherichia coli.  J Biol Chem, 274;33:23052-23060, 1999.

Abraham OC, Chandrasekar PH.  Emergence of antimicrobial-resistant infections in cancer patients.  Indian J Med Microbiol (In press)

Abraham OC, Alangaden GJ, Chandrasekar PH. Cervical adnitis due to Mycobacterium fortuitum in a patient with AIDS.  Infect Dis Clin Pract. (In press)

Abraham, O C, Manavathu EK, Cutright JL, Chandrasekar PH.  In vitro susceptibilities of Aspergillus species to voriconazole, itraconazole and amphotericin B. Diag Microbiol Infect Dis, 33: 7-11, 1999.

Aeschlimann J, Dresser L, Kaatz G, Rybak M: Effects of NorA inhibitors on in vitro antibacterial activities and postantibiotic effects of levofloxacin, ciprofloxacin, and norfloxacin in genetically related strains of Staphylococcus aureus. Antimicrob. Ag Chemother. 43:335-340, 1999.

Aeschlimann J, Kaatz G, Rybak M: The effects of NorA inhibition on the activities of levofloxacin, ciprofloxacin and norfloxacin against two genetically related strains of Staphylococcus aureus in an in-vitro infection model. J. Antimicrob. Chemother. 44:343-349, 1999.

AIDS (CPCRA).  Evolution of vaginal Candida species recovered from HIV-infected women receiving fluconazole prophylaxis: The emergence of  Candida glabrata?  Clin Infect Dis 28:1025-31, 1999.

Bajjoka IE, Bailey EM, Vazquez JA, Abouljoud MS.   Combination antifungal therapy for invasive aspergillosis infection in liver transplant recipients: report of two patients.  Pharmacother 19:118-123, 1999.

Ben-Josef AV, Manavathu EK, Platt D, Sobel JD.  Involvement of calcium inhibitable binding to the cell wall in the fungicidal activity of CAN-296.  J Antimicrob Chemo 44:217-222, 1999.

Ben-Josef, AM, Manavathu EK, Platt D, Sobel JD.  Proton translocating ATPase-mediated fungicidal activity of a novel complex carbohydrate: CAN-296. Intl J Antimicrob Ag, 13:287-295, 1999.

Birk TJ, McGrady A, MacArthur RD, Khuder S.  The effects of massage therapy alone and in combination with other complementary therapies on immune function and quality of life in HIV.  J Alternative and Complementary Medicine, (In press)

Brown PD.  Antibiotic Selection for UTI: new microbiologic considerations.  Curr Infect Dis Reports 1:384-388, 1999.

Chandrasekar PH, Alangaden G, Manavathu E.  Aspergillus Ð A rising problem in tertiary care hospitals? Clin Infect Dis (In press)

Chandrasekar PH, Cutright JL, Manavathu EK.  Efficacy of voriconazole against invasive pulmonary aspergillosis. J Antimicrob Chemother (In press).

Chandrasekar PH.  Management of fever in neutropenia cancer patients: Review. Hospital Physician (In press)

Chandrasekar, PH, Cutright JL, Manavathu EK.  Efficacy of voriconazole vs. amphotericin B in the guinea pig model of pulmonary aspergillosis. J Antimicrob Chemother 44 (Suppl. A) 53, 1999.

Chandrasekar, PH, Manavathu EK,. Alangaden GJ. Aspergillus - a rising problem in tertiary care hospitals? Clin Infect Dis,  (In press).

Chow JW, Yu VL.  Combination antibiotic therapy vs. monotherapy for gram-negative bacteremia: a commentary. Internat J Antimicrob Agents 11:7-12, 1999.

Cinti SK, Kaul DR, Sax PR, Crane LR, Kazanjian PH: Recurrence of mycobacterium avium infection in patients receiving highly active antiretroviral therapy and antimycobacterial Agents. Clin Infect Dis (In press)

Cu-Uvin S, Hogan JW, Warren D, Klein RS, Peipert J, Schuman P, Holmberg, Anderson J, Schoenbaum E, Vlahov D, Mayer KH.  Prevalence of lower genital tract infections among human immunodeficiency virus (HIV)-seropositive and high-risk HIV-seronegative women.  Clin Infect Dis 29(5)1145-1150, 1999.

Dworkin MS, Sullivan PS, Buskin SE, Harrington RD, Olliffe J, MacArthur RD, Lopez DE. Bordetella bronchiseptica infection in Human Immunodeficiency Virus-infected patients. Clin Infect Dis 28:1095-9, 1999.

Ebright J, Chandrasekar PH, Marks S., Fairfax MR, Aneziokoro A, McGinnis MR.  Invasive sinusitis and cerebritis due to curvularia clavata in an immunocompetent adult.  Clin Infect Dis 28:687-9, 1999.

Ebright J, Moldenhauer J, Gonik B.  Nonsurgical management of post cesarean endomyometritis with myometrial gas formation. Infect Dis Obstet Gynecol (In press)

Ebright JR, Chandrasekar PH, Marks S, Fairfax MR, Aneziokoro A, McGinnis MR. Invasive sinusitis and cerebritis due to Curvularia clavata in an immunocompetent adult.  Clin Infect Dis 28:687-689, 1999.

El-Sadr WM, Burman WJ, Bjorling Grant L, Matts JP, Crane L, Zeh D, Gallagher B, Mannheimer S, Martinez A, Hafner R, Gordin F:  Prophylaxis for mycobacterium avium complex disease can be safely deferred or discontinued among HIV-infected patients who experience CD4 cell rebound with antiretroviral therapy: results of a randomized placebo-controlled multicenter trial: CR-MAC Study (CPCRA 048).  N Engl J Med, (In press).

El-Sadr WM, Luskin-Hawk R, McCurik TM, Walker J, Abrams D, St Johns, Sherer R, Crane LR, Labrioloa A:  a randomized trial of daily and thrice weekly trimethoprim sulfamethoxazole for the prevention of Pneumocystis carinii pneumonia in HIV-Infected individuals.  Clin Infect Dis, 29:775-783, 1999.

Espinel-Ingroff A, Vazquez JA, Boikov D, Pfaller MA.  Evaluation of DNA-based typing procedures for strain categorization of Candida spp.  Diagn Microbiol Infect Dis 33(4):231-9, 1999.  Fidel PL Jr, Vazquez JA, Sobel JD.  Candida glabrata:  review of epidemiology, pathogenesis and clinical disease.  Clinic Micro Review 12:80-96, 1999.

Fidel PL, Vazquez JA, Sobel JD.  Candida glabrata: review of epidemiology, pathogenesis and clinical disease with comparison to C. albicans.  Clin Microbiol Rev 12:80-96, 1999.

Flanigan TP, Hogan JW, Smith D, Schoenbaum E, Vlahov D, Schuman, Mayer K.  Self-reported bacterial infections among women with or at risk for human immunodeficiency virus infection.  Clin Infect Dis 29:608-12, 1999.

Foxman B, Barlow R, dÕArcy H, Gillespie B, Sobel JD.  Candida vaginitis:  self-reported incidence and associated costs.  Sex Trans Dis (In press).

Foxman B, Barlow R, dÕArcy H, Gillespie B, Sobel JD.  Urinary tract infection:  self-reported incidence and associated costs.  Ann Epidemiol (In press).

Foxman B, Gillispie B, Koopman J, Zhang L, Palin K, Tallman P, Marsh JV, Spear S, Sobel JD, Marty MJ, Marrs CF.  Risk factors for second urinary tract infection among college women.  Am J Empidemiol (In press).

Graybill JR, Sobel JD, Saag M, VanderHorst C, Powderly W, Cloud G, Riser L, Hamill R, Dismukes W.  Diagnosis and management of increased intracranial pressure in patients with AIDS and cryptococcal meningitis.  Clin Infect Dis 30:47-54, 2000.

Harlow S, Schuman P, Cohen M, Ohmit SE, Cu Uvin S, Lin X, Anastos K, Burns D, Young M, Mucerspach L, Rompalo A, Minkoff H, Warren D, Greenblatt R. The effect of HIV infection on menstrual cycle length. JAIDS (In press).

Hidalgo JA, Alangaden GJ, Akins RA, Abrams GW, Eliott D, Puklin J, Vazquez JA.  Diagnosis of fungal endophthalmitis by detection of Candida albicans DNA in intraocular fluid using a species-specific PCR.  J Infect Dis (In press).

Hidalgo JA, Logani S, MacArthur RD.  Pulmonary mucormycosis in an AIDS patient: case report and review of the literature.  Infect Dis Clin Prac, (In press)

Hidalgo JA, MacArthur RD, Crane LR.  An overview of HIV infection and AIDS.  Sem Cardiovasc Surg, (In press)

Hillier SL, Schwebke JR, Sobel JD, McGregor JA, Sweet RL.  Clinical evaluation of the FemExam Testcard for detection of elevated pH and trimethylamine.  Sex Trans Dis (In press).

Jandourek A, Brown P, Vazquez JA.  Community acquired fungemia due to a multi-azole resistant Candida tropicalis.  Clin Infect Dis 29:1583-1584, 1999.

Kaatz G, Seo S, Foster T: Introduction of a norA promoter-region mutation into the chromosome of a fluoroquinolone-susceptible strain of Staphylococcus aureus using plasmid integration. Antimicrob. Agents Chemother. 43:2222-2224, 1999.

Kak V, Levine DP: Community-acquired methicillin-resistant staphylococcus aureus infections Ð where do we go from here? Clin Infect Dis 29:801-802, 1999.

Kak V, MacArthur RD, Crane LR.  Treatment of HIV disease in the new millennium. Sem Cardiovasc Surg, (In press)

Kanno MB, Brown PD.  Community-acquired pneumonia: an overview.  Curr Infect Dis Reports 1:49-56, 1999.

Kaufmann C, Vazquez JA, Sobel JD, Gallis HA, McKinsey DS, Karchmer AW, Sugar AM, Sharkey PK, Wise GJ, Mangi R, Mosher A, Lee JY, Dismukes WE, and the NIAID Mycoses Study Group  A prospective multicenter surveillance study of funguria in hospitalized patients.  Clin Infect Dis 30:14-18, 2000.

Klein R, Arnstein J, Sobel JD.  Oropharyngeal Candida colonization and human immunodeficiency virus type-1 infection.  J Infect Dis (In press).

Klein R, Mayer K, Schuman P, Vlahov D, Holmberg S. The effect of immunodeficiency on cutaneous delayed-type hypersensitivity testing in HIV-infected women without anergy: implications for tuberculin testing. Int J Tuberc Lung Dis 3(8):681-699, 1999.

Klein RS, Sobel JD, Flanigan T, Smith D, Margolick JB and the HIV Epidemiology Research Study Group.  Stability of cutaneous anergy in women with or at risk for HIV infection.  J Acquired Imm Def Synd and Human Retrovir 20:238-244, 1999.

Liu C, Abate B, Reyes M, Gonik B.  Single daily dosing of gentamicin:  pharmacokinetic comparison of two dosing methodologies for postpartum endometritis.  Infect Dis Obstet Gyecol 7:133-137, 1999.

MacArthur RD, Crane LR, Cohn JA.  Antiretroviral Recommendations, Detroit Medical Center. Updated annually; adopted by the State of Michigan AIDS Drug Assistance Program, and distributed widely to health care professionals (multistate area).

MacArthur RD, Lederman MM, Benson CA, Chernoff MC, MacGregor RR, Spritzler J, Mahon LF, Yen-Lieberman B, Purvis S.  Effects of treatment for MAC infection on cytokine expression in HIV-infected persons: results of AIDS Clinical Trials Group protocol 853. J Infect Dis (In press).

MacArthur RD.  Sequencing antiretrovirals.  The AIDS Reader, (In press)

Manavathu EK, Ben-Josef AV, Sobel JD.  Proton translocating ATPase mediated fungicidal activity of a novel complex carbohydrate:  CAN-296.  Internat J Antimicrob Ag (In press).

Manavathu EK, Kallakuri S, Arganoza MT, Vazquez JA.  Amino acid variations of cytochrome P450-dependent lanosterol 14a-demethylase from fluconazole-resistant clinical isolates of Candida albicans. Iberoamericana Micologia, 16:198-203, 1999.

Manavathu EK, Nune U, Kanuri K, Abraham OC, Cutright JL, Chandrasekar PH.  Effect of test medium on the in-vitro susceptibility of Aspergillus fumigatus to antifungal agents. Canadian J Microbiol (In press).

Manavathu EK, Vazquez JA, Chandrasekar PH.  Reduced susceptibility of aspergillus fumigatus to Itraconazole due to decreased intracellular accumulation of the antifungal agent.  Internat J Antimicrob Agents 12:213-219, 1999.

Manavathu, EK, Cutright JL, Chandrasekar PH.  A comparative study of the susceptibility of germinated and ungerminated conidia of Aspergillus fumigatus to various antifungal agents. J Clin Microbiol, 37: 858-861, 1999.

Manavathu, EK, Dimmock JR, Vashishtha SC, Cutright JL, Chandrasekar PH. Proton pumping ATPase directed antifungal activity of a novel conjugated styryl ketone. Antimcrob Ag Chemother, 43:2950-2959, 1999.

McNeil SA, Clark NM, Chandrasekar PH, Kauffman CA.  Successful treatment of vancomycin-resistant Enterococci faecium bacteremia with linezolid after failure of synercid Quinupristin/Dalfopristin) Treatment.  Clin Infect Dis (In press)

Moore J, Schuman P, Schoenbaum E, Boland B, Solomon L, Smith D.  Severe adverse life events and depressive symptoms among women with, or at risk for, HIV infections in four cities in the United States of America.   AIDS 13:2459-2468, 1999.

O’Neil WM, Drobitch RK, MacArthur RD, Farrough MJ, Doll MA, Fretland AJ, Hein DW, Crane LR, Svensson CK:  Acetylator phenotype and genotype in patients infected with HIV: Discordance between methods for phenotype determination and genotype.  Pharmacogenetics, (In press).

Phelps RM, Smith DK, Gardner L, Carpenter C, Klein RS, Vlahov D, Schuman P, Holmberg S. Incidence of cancer in women with or at risk for HIV infection. Arch Int Med (In press).

Prasad AS, Beck FWJ, Kaplan J, Chandrasekar PH, Ortega J, Fitzgerald JT, Swerdlow P.  Effect of zinc supplementation on incidence of infections and hospital admissions in sickle cell disease (SCD).  Am J Hematol 61:194-202, 1999.

Reilly TP, MacArthur RD, Farrough MJ, Crane LR, Woster PM, Svensson CK: Is hydroxylamine-induced cytotoxicity a valid marker for hypersensitivity reactions to sulfamethoxazole in HIV-infected individuals?  J  Pharmacol Exp Ther, 291:1356-1364, 1999.

Rex JH, Sobel JD.  Preventing intra-abdominal candidiasis in surgical patients.  Critical Care Medicine. 27:1033-1034, 1999.

Rex JH, Walsh TJ, Sobel JD, Filler SG, Pappas PG, Dismukes WE, Edwards JE: Treatment guidelines for candidiasis.  Clin Infect Dis (In press)

Rompalo A, Astemborski J, Schoenbaum E, Schuman P, Carpenter C, Holmberg S, Warren D, Farzadegan H, Vlahov D, Smith D.  Comparison of clinical manifestations of HIV infection among women by risk group, CD4+ cell count and HIV-1 plasma viral load. J AIDS Apr.15;20(5):448-54.

Saag MS, Cloud GA, Graybill JR, Sobel JD, et al.  A comparison of itraconazole versus fluconazole as maintenance therapy for AIDS-associated cryptococcal meningitis.  Clin Infect Dis 28:291-6, 1999.

Saag MS, Graybill JR, Larsen RA, Pappas PG, Perfect JR, Powderly WG, Sobel JD, Dismukes WE: Guidelines for the management of cryptococcal disease.  Clin Infect Dis (In press)

Sankar A, Luborsky M, Schuman P, Roberts G.  Adherence to anti-retroviral therapy among African American women: resources and challenges. AIDS & Behavior, (In press).

Sarma AV, Foxman B, Bagirli B, Haefner H, Sobel JD.  Epidemiology of vulvar vestibulitis syndrome:  an exploratory case control study.  Sex Trans Infect 75:320-326, 1999.

Schoenbaum EE, Chang CJ, Moore J, Mayer K, Schuman P, Rompalo A, Warren D.  Patterns in condom use among women participating in the HIV epidemiology research study. AIDS & Behavior (In press). 

Schuman P, Ohmit SE, Moore J, Schoenbaum E, Boland R, Rompalo A,  Solomon L for the HIV Epidemiology Research Study (HERS) Group.  Utilization of mental health services by women living with or at risk for HIV infection. AIDS & Behavior (In press).

Silverman J, Vazquez JA, Sobel JD, Zervos MJ.  Comparative in vitro activity of antiseptics and disinfectants versus clinical isolates of Candida species.  Infect Control & Hosp Epidemiol 20:676-684, 1999.

Sobel JD, Kauffman CA, McKinsey D, Zervos D, Vazquez JA, Panzer H, Dismukes W.  Candiduria in a randomized double blind study of treatment with fluconazole and placebo.  Clin Infect Dis 30:19-24, 2000

Sobel JD, McKinsey D, Kauffman C, Zervos MJ, Vazquez JA, Lee J and the Mycosis Study Group, NIAID.  Asymptomatic candiduria - a randomized, double blind study of treatment with fluconazole and placebo.  Ann Intern Med (In press).

Sobel JD, Nagappan, V, Nyirjesy P.  Metronidazole-resistant vaginal trichomoniasis Ð an emerging problem.  N Engl J Med 341:292-293.Sobel JD, Vazquez JA.  Fungal infections of the urinary tract.  World J Urol (In press).

Sobel JD, Vazquez JA:  Urinary tract infections due to fungi.  World J of Urology 17:410-4, 1999.

Sobel JD.  Mass or syndromic treatment of sexually transmitted diseases.  Curr Infect Dis Reports 1:365-366, 1999.

Sobel JD.  Protective role of vaginal flora.  Curr Infect Dis Reports 1:379-383, 1999.

Sobel JD.  Treatment of fungal disease in pregnancy.  ADIS Publication, (In press).

Sobel JD.  Vulvovaginitis in healthy women.  Comprehensive Ther 25:335-346, 1999.

Sobel JD:  Asymptomatic candiduria, review of treatment.  Internat J Antimicrobial Ag 11:285-288, 1999.

Sobel JD:  Bacterial vaginosis.  Ann Rev Med 57:29-47, 2000.

Sobel JD:  Diagnostic considerations in microscopy-negative Candida vaginitis.  Ital J Gynecol  Obstet 2:73-78, 1999.

Sobel JD:  Diagnostic strategems in the management of patients with acute and chronic vaginitis.  Contemporary Obstet Gynecol (Canada) (In press).

Sobel JD:  Limitations of antifungal agents in the treatment of Candida vaginitis:  future challenges. Drug resistance Updates 2:148-153, 1999.

Vazquez JA, Sobel J, Peng G, Schuman P, Steele-Moore L, Holloway W and Neaton J for the Terry Beirn Community Programs for Clinical Research in AIDS (CPCRA).  Evolution of vaginal candida species recovered from HIV-infected women receiving flucanazole prophylaxis: The emergence of candida glabrata?  Clin Infect Dis 28:(3)1025-1031, 1999.

Vazquez JA.   Options for the management of mucosal candidiasis in patients with AIDS and HIV infection.  Pharmacother 19:76-87, 1999.

Vazquez JA.  Strategies in the management of vulvovaginal candidiasis.  Excepta medica Asia, Ltd., Elsevier Science, Amsterdam, (In press).

Vazquez, JA.  Epidemiology of Candida vulvovaginitis: emergent species and antifungal susceptibility. Rev. Iberoamericana de Micología (In press).

Villanueva AV, Sahouri MJ, Ormerod LD, Puklin JE, Reyes MP.  Posterior uveitis in patients with positive serology for syphilis.  Clin Infect Dis (In press).

Villanueva, A., Chandrasekar, P.H.   Parvovirus B19 infection presenting as aplasia and pain crisis in a patient with sickle cell disease.  Hospital Physician June, pp. 64-71, 1999.

Weingarten CM, Rybak MJ, Brown WJ, Jahns BE, Stevenson JG, Levine DP.   An evaluation of acinetobacter baumannii infections and antimicrobial treatment patterns in an urban teaching hospital.  Pharmacother 19:1080-1085, 1999.

Yoon SA, Vazquez JA, Steffan PE, Sobel JD, Akins RA.  High frequency, in vitro reversible switching of Candida lusitaniae clinical isolates from amphotericin B-susceptible to resistance.  Antimicrob Ag Chemother 43:836-845, 1999.

You I, Kariyama R, Zervos MJ, Kumon H, Chow JW.   In-vitro activity of arbekacin alone and in combination with vancomycin against gentamicin- and methicillin-resistant staphylococcus aureus. Diagn Microb Infect Dis  (In press) 

Zierler S, Mayer K, Moore J, Stein M, Schoenbaum E, Schuman P, Rompalo A.  Sexual practices in a cohort of HIV seropositive and HIV seronegative US women. JAMWA. Spring; 54(2):79-83, 1999.

Books, Chapters and Reviews

Alangaden GJ. Leptospirosis. In: KellyÕs Textbook of Internal Medicine (Fourth edition). Lippincott Williams & Wilkins, New York. 299:199-201 (In press).

Chow JW, Shlaes DM. Enterococcus species. In: Yu VL, Merigan TC, Jr., Barriere SL, eds. Antimicrobial therapy and vaccines. Baltimore, MD: Williams and Wilkins; 1999.

Fidel PL Jr, Sobel JD.  Murine models of Candida vaginal infection.  In: Handbook of animal models of infection.  Zak O, Sande M (Editors), Academic Press, Guersney UK, Chapter 3, (In press).

Lerner SA, Brown PD.  Antimicrobial therapy and vaccines.  N Engl J Med 341:771-72, 1999.

Lundstrom TS, Crane L.  Human immunodeficiency virus and acquired immunodeficiency syndrome.  In:  APIC Infection Control and Applied Epidemiology:  Principles and Practice, R Olmstead (Editor), Mosby Year Book, Inc, St. Louis, Missouri (In press).

Lundstrom TS, Sobel JD.  Antibiotics for gram positive bacterial infections:  vancomycin, teicoplanin, quinupristin/dalfopristin and linezolid.  In:  Infect Dis Clin N Am, D. Kaye (Editor), W.B Saunders Co, Philadelphia, PA.  (In press)

Lundstrom TS, Sobel JD:  Fungal infections.  In:  APIC Infection Control and Applied Epidemiology:  Principles and Practice, R Olmstead (Editor), Mosby Year Book Publishers, St. Louis, Missouri (In press).

MacArthur RD, Abbas M. Sepsis and septic shock.  In: Schlossberg D, ed. Current Therapy of Infectious Disease.  Philadelphia: Mosby. (In press).

MacArthur RD.  Infections: etiology, prevention, and treatment.  In: Skeel RT, ed. Handbook of Cancer Chemotherapy (5th ed).  Philadelphia: Lippincott Williams & Wilkins. 574-97, 1999.

Sobel JD, Kaye D.  Urinary Tract Infections.  In:  Principles and practice of Infectious Diseases.  Mandell G, Bennett J, Dolin R (Editors), Churchill Livingston, Philadelphia, PA, 5th Edition, Vol 1, Chapt 62, pp 773-805, 2000.

Sobel JD, Vazquez J:  Fungal infections of the urinary tract.  In: Comprehensive Clinical Nephrology, RJ Johnson, J Feehally (Editors), Mosby International, Chapt 58, Section 10, pp 58.1-58.6, 1999.

Sobel JD, Vazquez JA.  Fungal infections in the critically ill.  In: Infections in the ICU.  HKF van Saene (Ed.), Oxford University Press, Liverpool, UK.  (In press).

Sobel JD.  Biotherapeutic agents as therapy for vaginitis.  In:  Probiotic therapy, GW Elmer, LV McFarland, CM Surawicz (Editors), Humana Press, Inc, Totowa, NJ, 221-244, 1999.

Sobel JD.  Mucocutaneous candidiasis.  In: Fungal Infections, R Diamond (Editor), Atlas of Infectious Diseases (In press).

Sobel JD:  Candida vaginitis.  In: Infectious Diseases in Obstetrics and Gynecology, S Faro, M Maartens, D Soper (Editors), WB Saunders, (In press).

Sobel JD:  Candida vaginitis.  In: Vulvovaginal disease, Ledger W and Witkin J (Editors), W.B. Saunders Co, New York, NY, (In press).

Sobel JD:  Candiduria.  In:  Current Therapy of Infectious Diseases, Schlossberg D (Editor), Mosby Year Book, Philadelphia, PA. (In press).

Sobel JD:  Cervicitis.  In:  America College of Physicians (In press)

Sobel JD:  Fungal infections of the genitourinary tract.  In: Clinical Mycology, E Anaissie, M McGinnis, M. Pfaller (Editors), WB Saunders, (In press).

Sobel JD:  Genital candidosis.  In:  International Standard Book for Infectious Diseases in Obstetrics, Gynecology, Dermatology, Urology, and Clinical Immunology, Weissenbacher ER (Editor), Medifact Publishing House, Munich, Germany (In press)

Sobel JD:  Urinary tract infections:  Uncomplicated, complicated, and nosocomial.  In:  Curr Prac Med.  FT Fitzgerald (Editor), Vol 2, Number 4, Chapter 164:555-562, 1999.

Sobel JD:  Vaginitis.  In:  American College of Physicians (In press)

Sobel JD:  Vulvitis, vaginitis and cervicitis.  In: Infectious Disease, D Armstrong, Cohen J (Editors), Mosby, London, United Kingdom (In press).

Sobel JD:  Vulvovaginal candidosis.  In: Medicine, UK, (In press).

Vazquez JA.  Applications of PCR in mycology.  (Book Review).  Bridge, PD, Arora DK, Reddy CA, and Elander RP (Eds) (CAB International). Mycopathologia.(In press).

Vazquez JA.  Zygomycosis (mucormycosis, phycomycosis).  Medicine, OB-GYN, Psychiatry, and  Surgery. eMedicine.com (In press).

Yoon SA, Boikov D, Vazquez JA, Akins RA.  Identification and characterization of atypical Candida parapsilosis isolates. In: Programs and Abstracts of the 5th Candida and Candidiasis Meeting, Charleston, South Carolina, March 1-4, 1999.

Abstracts, Letters to the Editor and Articles in Non-Refereed Journals

Abraham OC, Klein J, Chalasani G, Cassells L, Dansey R, Abella S, Karanes C, Peters W, Baynes R, Chandrasekar PH.  Infectious complications in women undergoing autologous peripheral blood progenitor cell transplantation (PBPCT) for breast cancer.  In: Programs and Abstracts of 37th Annual Meeting of the Infectious Diseases Society of America, Philadelphia, PA, November 1999.

Berman W, Crane LR: Low Rates of All Opportunistic Infections Among  Patients with Advanced HIV Disease Responding to Antiretroviral Therapy...the CPCRA 048 Cohort.  Abst 241 7th Conference on Retroviruses and Opportunistic Infections.  2000 San Francisco

Brown PD, Jandourek A, Vazquez JA.  Communityacquired fungemia due to a multi-azole resistant Candida tropicalis. Infectious Diseases Society of America 37th Annual Meeting. Philadelphia, Pennsylvania 1999.

Cheng P, Doyle M, Panthangi V, Rahman A, MacArthur RD, Kosmyna JM, Crane LR, Podzorski R, Draghici S, Kovari LC: Mechanisms of HIV-1 Protease Drug Resistance.  Abst 448 Infectious Diseases Society of American Nov 18-21, 1999.

Cinti SK, Gallant JE, Sax PE, Crane L, Armstrong W, Kaul D, Kazanjian P: Breakthrough of Mycobacterium avium Infection in Patients Responding to HAART and Receiving Antimycobacterial Treatment.  Abst 410 Infectious Diseases Society of American Nov 18-21, 1999

Douglas MA, Levine DP.  Hallucination in an elderly patient taking recommended doses of cyclobenzaprine.  Arch Int Med (In press).

Eliott D, Vazquez JA, Abrams G, Akins R, Puklin J.  New diagnostic techniques for fungal endophthalmitis.  Vitreoretinal Meeting, Rome, Italy, September 21-25, 1999.

El-Sadr W, Burman W, Grant L, Matts JP, Zeh D, Crane LR, Gallagher B, Gordin F: Prophylaxis for Mycobacterium avium Complex can be deferred among patients with a past CD4 Count <50 Who Responded to Antiretroviral Therapy Abst 247. 7th Conference on Retroviruses and Opportunistic Infections. 2000 San Francisco.

Espinel-Ingroff A, Perfect J, Pickward W, Steele-Moore L, Akins R, and Vazquez JA.  DNA subtyping and azole MICs for Candida glabrata during voriconazole therapy.  In: Programs and Abstracts of the 5th Candida and Candidiasis Meeting, Charleston, South Carolina, March 1-4, 1999.

Gardner L, Smith D, Stone V, Howard A, Schuman P, Rompalo A, Hamburger M, Holmberg, S. Adherence to antiretroviral medications in the HERS study.  39th Interscience Conference on Antimicrobial Agents and Chemotherapy.  Abstract No. 592. September 26-29, 1999.

Hedderwick S, Lyons M, Liu M, Vazquez J, Kauffman C.  Epidemiology of yeast colonization in the intensive care unit.  9th European Congress of Clinical Microbiology and Infectious Diseases 5(Suppl 3):281, 1999, March 21-24, 1999.

Hershberger E, Coyle E, Kaatz G, Zervos M, Rybak M. In vitro fibrin-clot infection model versus rabbit model of bacterial endocarditis. ICAAC 39:A23, 1999.

Hidalgo JA, Akins RA, Brown W, Vazquez JA.  Invasive Candida dubliniensis infection in a non-HIV-positive patient.  Verification with RAPD and a species-specific probe.  In: Programs and Abstracts of the 37th Annual Meeting of the Infectious Diseases Society of America.  Philadelphia, Pennsylvania, November 18-21, 1999.

Hidalgo JA, Alangaden GJ, Akins RA, Abrams GW, Eliott D, Puklin J, Chandrasekar PH, Vazquez JA. Diagnosis of fungal endophthalmitis by detection of Candida albicans DNA in vitreous specimens using a species-specific PCR. In: Programs and Abstracts of 37th Annual Meeting of the Infectious Diseases Society of America, Philadelphia, PA, November 1999.

Hidalgo JA, Vazquez JA.  Candida dubliniensis in an immunocompetent patient presenting with an intra-abdominal abscess.  American College of Physicians Fall Scientific Meeting, Traverse City, Michigan, September 24-26, 1999.

Issa N, Kak V, Brown P.  Post endoscopic retrograde cholangiopancreatography cholangitis due to Streptococcus pneumoniae: an unusual case. American College of Physicians Associates Meeting. Detroit, Michigan 1999.

Kaatz G, Seo S, OÕBrien L, Hartford O, Foster T:  Comparison of sequence disruption versus deletion of norA in Staphylococcus aureus 8325-4. ICAAC 39:C810, 1999.

Kaatz G, Seo S:  A mutation in a perfect inverted repeat in the promoter of norA affects gene expression. ICAAC 39:C672, 1999.

Kak V, You I, Zervos MJ, Chow JW.  In-vitro synergistic activity of ampicillin and arbekacin against vancomycin-resistant enterococcal isolates with high level aminoglycoside resistance due to APH(2Ó). In: Program & Abstracts 39th Interscience Conference on Antimicrobial Agents & Chemotherapy, 1999.

Kariyama R, Kumon H, Zervos MJ, Chow JW.  Combinations of ampicillin, fosfomycin, and arbekacin against (-lactam, glycopeptide-, and high-level gentamicin-resistant Enterococcus faecium. Abstr. #P523. 21st International Congress of Chemotherapy, 1999.

Kazanjian P, Armstrong  W, Hossler PA, Richardson J, Crane LR, Katz J, Burman R, Meshnick S: Pneumocystis carinii mutations are associated with duration of sulfa prophylaxis and with sulfa treatment failure and in AIDS Patients. Abst 229. 7th Conference on Retroviruses and Opportunistic Infections. 2000 San Francisco.

Levine DP and the Clinafloxacin Study Group. Clinafloxacin monotherapy for prosthetic valve endocarditis. Fifth International Symposium on Modern Concepts in Endocarditis and Cardiovascular Infections. Amsterdam, The Netherlands. July 1-3, 1999.

MacArthur RD, Kosmyna JM, Crane LR, Kovari L, Podzorski R.  Sequencing of non-nucleoside reverse transcriptase inhibitors based on specific mutational patterns fails to lower plasma HIV-RNA levels in persons extensively pre-treated with antiretrovirals who are failing virologically on nevirapine-containing antiretroviral regimens.  Abstracts of the Seventh European Conference on Clinical Aspects and Treatment of HIV-Infection, 208, 1999.

MacArthur RD, Kosmyna JM, Crane LR, Kovari L.  The presence of absence of zidovudine in a nevirapine-containing antiretroviral regimen determines which of two nevirapine-limiting mutations occurs on virologic failure.  Abstracts of the 39th ICAAC, 1171, 1999.

Manavathu, EK, Abraham OC, Cutright JL, Chandrasekar PH.  Isolation and in vitro susceptibility to amphotericin B (AMB), itraconazole (ITZ) and SCH56592 (SCH) of voriconazole (VCZ)-resistant laboratory isolates of Aspergillus fumigatus. In: Abstracts of the 99th General Meeting of the American Society for Microbiology, Abstract A69, 1999.

Manavathu, EK, Cutright JL, Chandrasekar PH. Species diversity and in vitro antifungal susceptibility of clinical isolates of Aspergillus obtained in a Medical Center from January 1994 to December 1998. In Abstracts of the 39th Interscience Conference on Antimicrobial Agents and Chemotherapy, Abstract 1512. p. 570, 1999.

Manavathu, EK, Dimmock JR, Chandrasekar PH.  H+-ATPase-dependent activity of a novel conjugated styryl ketone against Cryptococcus neoformans. In Abstracts of the 39th Interscience Conference on Antimicrobial Agents and Chemotherapy, Abstract 1942. p. 345, 1999.

Manavathu, EK, Loebenberg D, Cutright JL, Chandrasekar PH.  A comparative study of the in vitro susceptibility of Aspergillus species to SCH56592 (SCH), amphotericin B (AMB), itraconazole (ITZ) and voriconazole (VCZ). In: Abstracts of the 99th General Meeting of the American Society for Microbiology, Abstract A121, 1999.

McKinnon P, Nagappan V, Levine DP, Rybak M.  Evaluation of pharmacodynamics and clinical and microbiologic outcomes of infective endocarditis in patients treated with once daily aminoglycosides.  Fifth International Symposium on Modern Concepts in Endocarditis and Cardiovascular Infections. Amsterdam, the Netherlands.  July 1-3, 1999.

McKinnon P, Nagappan V, Rybak M, Levine DP.  Evaluation of clinical and microbiologic outcomes of infective Endocarditis in patients treated empirically with vancomycin a beta-lactam or a fluoroquinolone.  Fifth International Symposium on Modern Concepts in Endocarditis and Cardiovascular Infections.  Amsterdam, The Netherlands.  July 1-3, 1999.

Meghashyam J, Thal L, Donabedian SM, Chow J, Zervos MJ.  Molecular evaluation of vancomycin-resistant Enterococcus faecalis in Michigan hospitals. Program & Abstracts 39th  Interscience Conference on Antimicrobial Agents & Chemotherapy, 1999.

Odemuviwa A., Alav F, Ebright JR. Systemic sclerosis and graves disease:  A rare association. Am College of Physicians AssociatesÕ Meeting, Southfield, MI, May 7, 1999.

Reichelderfer P, Coombs R, Wright D, Burns D, Cohn J, Kovacs A, and the WHS 001 Study Group. Variation in genital tract shedding of HIV RNA with the menstrual cycle.  Sixth Conference on Retroviruses and Opportunistic Infections, Chicago IL, January 31 1998 Ð February 4 1999.  Program and abstracts p110 (abstract# 223), 1999.

Rybak M, Hershberger E, Thomas A, Seo S, Kaatz G:  Evaluation of newer fluoroquinolones against vancomycin-intermediate Staphylococci (VISA), coagulase-negative Staphylococcus (VICNS), and MRSA. ICAAC 39:E377, 1999.

Sakka W, Palakurthi L, Ebright JR. Enterococcal meningitis in an adult.  American College of Physicians AssociatesÕ Meeting, Southfield, MI, May 7, 1999.

Schuman P, Ohmit SE, Cohen M, Sacks H, Schoenbaum E, Rompalo A, Richardson J, Young M, DaVenny K.  Prescription of anti-retroviral therapy (ART rx) by health care providers to women: report from the HIV epidemiology research study (HERS) and womenÕs inter-agency HIV study (WIHS).  The 1999 National Conference of Women and HIV/AIDS. oral presentation., Los Angeles, California. Abstract No.157. October 9-12, 1999.

Schuman P, Ohmit SE, Jones TB, Laken MP.  HIV counseling and testing of pregnant women; An assessment of compliance with Michigan statutes.  The 1999 National Conference on Women and HIV/AIDS.  Round Table Presentation.  October 9-12, 1999.

Schuman P, Ohmit SE, Vazquez J, Klein RS, Mayer K, Rompalo A, Jamieson D, Sobel JD. Longitudinal assessments of oral and vaginal candida colonization, species and fluconazole susceptibility in HIV seropositive women.  The HER Study. 7th Conference on Retroviruses and Opportunistic Infections.  San Francisco, California.  Abstract No.    January 30-February 2, 2000. 

Schuman P, Vazquez J, Klein RS, Mayer K, Rompalo A, Sobel JD.  Evolution of fluconazole susceptibility among Candida isolates.  In: Programs and Abstracts of the 6th Conference on Retroviruses and Opportunistic Infections, Chicago, Illinois, January 31 Ð February 4, 1999, Abstract #184, 1999.

Thatai LC, Vazquez JA.  Concomitant aspergilloma and pulmonary blastoma diagnosed intra-operatively: Case report and review.  American College of Physicians Fall Scientific Meeting, Traverse City, Michigan, September 24-26, 1999.

Thomas D, Smith D, Flanigan T, Schuman P, Klein RS.  Determinants of hepatitis C viral load in women with or at risk for HIV infection.  37th Annual Infectious Diseases Society of America, Philadelphia, Pennsylvania. Abstract No.718.  November 18-21, 1999.

Vakulenko SB, Lerner SA:  Evolution of the TEM-1 (-lactamse to confer resistance to cefepime (CPM) and/or ceftazidime (TAZ) following intensive mutagenesis, 99th General Meeting, American Society for Microbiology, (A-27), 1999.

Vakulenko SB, Lerner SA:  Mutational alteration in substrate specificity of class C P99 (-lactamase, International Congress on (-Lactamases, LÕAquila, Italy, 1999.

Vakulenko SB, Mobashery S, Lerner SA:  Extended-spectrum (E-S), inhibitor-resistant mutants of the TEM-1 (-lactamase, 39th International Conference on Antimicrobial Agents and Chemotherapy, (2048), 1999.

Vazquez JA, Yoon SA, Akins RA.  Characterization of in vitro reversible switching of Candida lusitaniae clinical isolates from amphotericin B-susceptible to resistant phenotypes.  In: Programs and Abstracts of the 5th Candida and Candidiasis Meeting, Charleston, South Carolina, March 1-4, 1999.

Vazquez JA, Yoon SA, Akins RA.  Phenotypic and molecular characterization of a bid-directional switching mechanism from amphotericin B-susceptibility to resistant in C. lusitaniae clinical isolates.  In: Programs and Abstracts of the 39th Interscience Conference on Antimicrobial Agents and Chemotherapy, San Francisco, California, September 26-29, 1999.

Vergis EN, Shankar V, Gilmore M, Chow JW, Hayden MK, Snydman DR, Zervos MJ, Linden PK, Wagener MM, Muder RR.  Characterization of virulence factors in patients with Enterococcus faecalis bacteremia. Program & Abstracts 39th Interscience Conference on  Antimicrobial Agents & Chemotherapy, 1999.

Vijayalakshmi N, McKinnon P, Rybak M, Levine D.  Clinical features, microbiology, complications and treatment outcomes in patients with infective endocarditis: right-sided vs. left-sided diseases.  Fifth International Symposium on Modern Concepts in Endocarditis and Cardiovascular Infections.  Amsterdam, The Netherlands.  July 1-3, 1999.

Wahiduzzaman M, Chandrasekar PH, Alangaden GJ.  High frequency of Gram-negative pneumonia in bone marrow transplant/ stem cell transplant (BMT) recipients with graft-vs-host disease (GVHD) and pulmonary aspergillosis. In: the Abstracts of the IDSA 37th Annual Meeting, November 18-21, Philadelphia, Pennsylvania. Clin Infect Dis. 29:1014, 1999.

Webber MP, Schoenbaum EE, Klein RS, and THE HER Study Group:(Schuman, P)  HIV collection from cervicovaginal secretions: comparing lavage and tampon methods.  37th Annual Infectious Diseases Society of America, Philadelphia, Pennsylvania. Abstract No. 449. November 18-21, 1999.

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