Features

Ophthalmology

Chair: Gary Abrams, MD
Kresge Eye Institute
(313) 577-1320

Articles
Allen, MY and Higginbotham, EJ. Impact of hormonal changes on the eye. The Female Patient 25(3):57-60, 2000.

Barr, D, Kupersmith, M. Turbin, R, Yang, S, Iezzi, R. Synkinesis following diabetic third nerve palsy. Archives of Ophthalmology 118:132-134, 2000.

Frank, RN, Puklin, JE, Stock, C, Canter, LA. Race, iris color, and age-related macular degeneration. Trans Amer Ophthalmol Soc 98:109-118, 2000.

Gimbel, HV, Iskander, NG, Peters, NT, Penno, EEA. Prevention and management of microkeratome related LASIK complications. Journal of Refractive Surgery 16:S226-229, 2000.

Gimbel, HV, Peters, NT, Iskander, NG, Penno, EEA. LASIK flap complications and management. Journal of Refractive Surgery. 16:S223-225, 2000.

Hayashi, F, Matsuura, I, Kachi, S, Maeda, T, Yamamoto, M, Fujii, Y, Yamazaki, M, Usukura, J, and Yamazaki, A. Phosphorylation of cylcin-dependent protein-kinase 5 of the regulatory subunit of retinal cGMP phosphodiesterse: 2. Its role in the GTP hydrolysis-independent turnoff of phosphodiesterase in living photoreceptors. Journal of Biological Chemistry 275:32958-32965, 2000.

Henry, DN, Frank, RN, Hootman, SR, Rood, SE, Heilig, CW, Busik, JV. Glucose-specific regulation of aldose reductase in human retinal pigment epithelial cells in vitro. Invest Ophthalmol Vis Sci 41:1554-1560, 2000.

Hidalgo, JA, Alangaden, GJ, Eliott, D, Akins, RA, Puklin, J, Abrams, G, Vazquez, JA. Fungal endophthalmitis diagnosis by detection of candida albicans DNA in intraocular fluid by use of a species-specific polymerase chain reaction assay. J Infect Dis 181:198-201, 2000.

Hurley, JB and Dizhoor, AM. Heterologous expression and assay of photoreceptor guanylyl cyclases and guanylyl cyclase activator proteins. Methods in Enzymology 315:708-718, 2000.

Iskander, NG, Peters, NT, Penno, EA, Gimbel, HV. Postoperative complications in laser in situ keratomileusis. Current Opinion in Ophthalmology. 11:273-279, 2000.

Kachi, S, Yamazaki, M, Tanaka, Y, Hayashi, F, Miyake, Y, Wakabayashi, T, Yamazaki, A and Usukura, J. Structural change of bovine retinal cGMP phosphodiesterase by release of its g subunits: Direct imaging by improved low angle rotary shadowing. Journal of Electron Microscopy 49:699-708, 2000.

Keltner, JL, Johnson, CA, Quigg, JM, Cello, KE, Kass, MA, Gordon, MA for the Ocular Hypertension Study Group. Confirmation of visual field abnormalities in the Ocular Hypertension Treatment Study (OHTS). Arch. Ophthalmol. 118:1187-1994, 2000.

Kern, TS, Tang, J, Mizutani, M, Kowluru, R, Nagraj, R, Lorenzi, M. Response of capillary cell death to aminoguanidine predicts the development of retinopathy: comparison of diabetes and galactosemia. Invest Ophthalmol Vis Sci 41:3972-3978, 2000.

Kowluru, RA, Engerman, RL, Kern, TS. Abnormalities of retinal metabolism in diabetes and galactosemia. VIII. Prevention by aminoguanidine. Current Eye Research 21:814-819, 2000.

Kowluru, RA, Engerman, RL, Kern, TS. Diabetes-induced metabolic abnormalities in heart. Free Radical Research 32:67-74, 2000.

Kraft, SP, Nabi, NU, Wilson, ME, Roarty, JD, et al. Bilateral idiopathic Brown’s Syndrome with delayed onset in the second eye. Journal of the American Association of Pediatric Ophthalmologists 4(3):158-163, 2000.

Matsuura, I, Bondarenko, VA, Maeda, T, Kachi, S, Yamazaki, M, Usukura, J, Hayashi, F, and Yamazaki, A. Phosphorylation of cyclin-dependent protein-kinase 5 of the regulatory subunit of retinal cGMP phosphodiesterse: 1. Identification of the kinase and its role in the GTP hydrolysis-independent turnoff of phosphodiesterase in vitro. Journal of Biological Chemistry 275:32950-32957, 2000.

Ober, MD, Lemon, LC, Shin, DH, Nootheti, P, Cha, SC, and Kim, PH. Posterior capsular opacification in phaco-trabeculectomy. A long-term comparative study of silicone versus acrylic intraocular lens. Ophthalmology 107:1868-1873, 2000.

Piltz, J, Gross, R, Shin, DH, Kass, MA, Gordon, MO, and the OHTS Group. Contralateral effect of topical ß-adrenergic antagonists in initial one-eyed trials in the Ocular Hypertension Treatment Study. Am J Ophthalmol. 130:441-453, 2000.

Qian, W, Shichi, H. Acetaminophen produces cataract in DBA2 mice by Ah receptor-independent induction of CYP1A2. J Ocular Pharmacol Therapeut 16:337-344, 2000.

Qian, W, Shichi, H. Cataract formation by a semiquinone metabolite of acetaminophen in mice: Possible involvement of a Ca²⁺ and calpain activation. Exp Eye Res 71:567-574, 2000.

Shin, DH and the Brinzolamide Adjunctive Therapy Study Group. Adjunctive therapy with Brinzolamide 1% ophthalmic suspension (AZOPTä) in patients with primary open-angle glaucoma or ocular hypertension maintained on timolol therapy. Surv Ophthalmol 44:S163-S168, 2000.

Van Stavern, GP, Biousse, V, Leingang, JC, Newman, NJ. Downbeat nystagmus in heat stroke. J Neurol Neursurg and Psychiatry. 69(3):403-404, 2000.

Villaneueva, AV, Sahouri, MJ, Ormerod, LD, Puklin, JE, Reyes, MP. Posterior uveitis in patients with positive serology for syphilis. Clin Infect Dis 30:479-485, 2000.

Beck, R, Frank, RN, et al. Growth hormone antagonist for proliferative diabetic retinopathy study group. The effect of a growth hormone receptor antagonist drug on proliferative diabetic retinopathy. Ophthalmology (in press).

Frank, RN. Role of VEGF and other mediators in the pathogenesis of diabetic retinopathy. Canad J Diabetes Care (in press).

Garcia-Valenzuela, E, Eliott, D. Serous retinal and choroidal detachment after macular hole surgery. Arch Ophthalmol (in press).

Kachi, S, Yamazaki, A, Usukura, J. Localization of caveolin-1 in photoreceptor synaptic ribbons. Invest Ophthalmol Vis Sci (in press).

Kowluru, RA, Tang, J, Kern, TS. Abnormalities of retinal metabolism in diabetes and galactosemia. VII. Effect of long-term administration of antioxidants on retinal oxidative stress and the development of retinopathy. (in press)

Peshenko, IV, Singh, AK, Shichi, H. Bovine eye 1-Cys peroxiredoxin: Expression in E. coli and antioxidant properties. J Ocular Pharmacol Therapeut (in press).

Rodriquez, NM, Eliott, D. Bilateral central retinal vein occlusion in Eisenmenger’s Syndrome. Am J Ophthalmol (in press).

Shin, DH, Birt, CM, O’Grady, JM, Kim, C, Juzych, MS, Lemon, LC, Reed, SY, and Eliassi-Rad, B. Transscleral suture fixation of posterior chamber lenses combined with trabeculectomy. (in press)

Singh, AK, Shichi, H. Peroxiredoxin in bovine ocular tissues: Immunohistochemical localization and in-situ hybridization. J Ocular Pharmacol Therapeut (in press).

Books, Chapters and Reviews
Abrams GW and Nanda, S. Retinotomies and retinectomies. In:Retina. (SJ Ryan, ed.) Mosby, Chapter 139, pp. 2317-2348, 2000.

Abrams, GW and Werner JC. Posterior segment surgery. In:Manual of Retinal Surgery. (AJ Packer, ed.) Butterworth-Heinemann, Chapter 8, pp. 69-104, 2000.

Bendel, RE, Juzych, MS. Principles and complications of medical therapy of glaucoma. In: Clinical Pathways in Glaucoma, Thieme Medical Publishers, New York, NY, 2000.

Dizhoor, AM. Regulation of cGMP synthesis in photoreceptors: Role in signal transduction and congenital diseases of the retina. Cellular Signalling 12:711-719, 2000.

Eliott D, Lee, MS and Abrams, GW. Proliferative diabetic retinopathy: Principles and techniques of surgical treatment. In:Retina (SJ Ryan, ed.) Mosby, Chapter 146, pp. 2436-2476, 2000.

Eliott, D, Schachat, AP. Combined hamartoma of the retina and retinal pigment epithelium. In: Retina (SJ Ryan, ed.) Mosby, St. Louis, pp. 640-646, 2000.

Fontanesi, J, Donaldson, SS, Pratt, CB, Halperin, EC, Roarty, JD. Retinoblastoma. In:Clinical Radiation Oncology, (LL Gunderson, JE Tepper, eds.), Churchill Livingstone, Philadelphia, Chapter 55, 2000.

Frank, RN. Etiologic mechanisms in diabetic retinopathy. In:Retina, (SJ Ryan, TE Ogden, AP schachat, CP Wilkinson, D Hinton, eds.), Harcourt-Mosby, St. Louis, pp. 1259-1294, 2000.

Lee, M and Abrams, GW. Membrane dissection in proliferative diabetic vitreoretinopathy. In:Atlas of Vitreoretinal Surgery (G Peymen, ed.) Martin Dunitz, Chapter 25, pp. 251-266, 2000.

Lee, M and Abrams, GW. Membrane removal in proliferative vitreoretinopathy. In:Atlas of Vitreoretinal Surgery (G Peymen, ed.) Martin Dunitz, Chapter 27, pp. 275-297, 2000.

Micheli-Tzanakou, E, Iezzi, R. Biological and machine vision. In:Supervised and Unsupervised Pattern Recognition: Feature Extraction and Computational Intelligence. (E Micheli-Tzanakou, ed.) CRC Press, New York, pp. 347-358, 2000.

Nesi, FA, Gladstone, GJ, Brazzo, BG, Myint, S, Black, EH. Ophthalmic and facial plastic surgery, a compendium of reconstructive and aesthetic techniques. Slack, Thorofare, NJ 2001.

Yamazaki, A. Proteins, separation by centrifugation (I Wilson, Ed.). Academic Press, London, pp. 4014-4020, 2000.

Allen, MY. Management of surgical complications. In:Clinical Management of Glaucoma. (EJ Higginbotham, DA Lee, eds.). Butterworth & Heinemann (in press).

Allen, MY, Higginbotham, EJ. Primary Open-Angle Glaucoma. In:Essentials of Glaucoma. (J Morrison and I Pollack, eds.). Thieme Medical and Scientific Publications (in press).

Gimbel, HV, Penno, EEA, Peters, NT, Iskander, NG. LASIK complications: Prevention and management. Slack, Thorofare, NJ (in press).

Van Stavern, GP, Newman, NJ. Optic neuropathies: An overview. In:Ophthalmology Clinics of North America (NJ Newman, ed), WB Saunders (in press).

Weiss, JS. Cornea and external disease. (K Wilhilmis, ed.), American Academy of Ophthalmology (in press).

Weiss, JS. Review of “Refractive surgery” by HK Wu, RF Steinert, et al. (G. Wong, ed.), Archives of Ophthalmology (in press).

Abstracts and Letters to the Editor
Barrow, D, McDermott, M, Eliott, D, Frank, R. Corneal epithelial defects after pars plana vitrectomy. Invest Ophthalmol Vis Sci , 41(S):912, 2000.

Berkowitz, B. Measuring the human retinal oxygenation response: Motion-artifact free MRI. Invest Ophthalmol Vis Sci 41(S):172, 2000.

Desmeules, P, Grandbois, M, Yamazaki, A, Gaub, H, Salesse, C. Effect of calcium on the binding of recoverin to membranes: An atomic force microscopy study. Invest Ophthalmol Vis Sci 41(S):606, 2000.

Dizhoor, AM. Regulation of photoreceptor membrane guanylyl cyclase (retGC) by calcium sensor proteins (GCAP). Proceedings of the International Society for Eye Research, Vol. XIV, p. S.179, 2000.

Dizhoor, AM, Ermilov, AN, Olshevskaya, EV. Ca²⁺-free GCAP activates photoreceptor guanylyl cyclase in a cooperative manner consistent with the cyclase dimerization mediated by GCAPs. Invest Ophthalmol Vis Sci 41(2):321, 2000.

Eliassi-Rad, B, Shin, DH, Nootheti, P, Morris, DA, Kim, PH, Brown, DJ, McVeigh, C, and Baek, NH. Comparative study of multifocal vs. monofocal foldable silicone IOL in glaucoma triple procedure. Ophthalmology 107(Suppl.):101, 2000

Esco, MA, McDermott, ML, Kurpakus-Wheater, M, Hazlett, LD. Extracellular matrix deposited by chronically hypoxic corneal epithelium is a preferred substrate for bacterial binding. Invest Ophthalmol Vis Sci, 41(S):153, 2000.

Gago, LC, Eliassi-Rad, B, Shin, DH, Kim, C, Juzych, MS, Hughes, BA, Nootheti, P, and Parrow, KA. Comparative study of the actual vs the calculated theoretical refractive error following glaucoma triple surgery in POAG patients vs phaco with PCIOL in nonglaucoma patients. ARVO Abstracts. Invest. Ophthalmol. Vis. Sci. 41(Suppl.):517, 2000.

Goulas, MT, Shin, DH, Kim, C, Eliassi-Rad, B, Schulz, L, Juzych, MS, Glover, BK, and Cha, SC. Comparison of long-term outcome of selective laser trabeculoplasty vs argon laser trabeculoplasty in chronic open-angle glaucoma patients with and without previous ALT. ARVO Abstracts. Invest Ophthalmol Vis Sci. 41(Suppl.):578, 2000.

Hamre, MR, Chuba, P, Severson, RK, Metzger, K, Roarty, J, et al. Increased incidence of unilateral and bilateral retinoblastoma among individuals of Hawaiian ethnicity. Med Pediatr Oncol 35:282, 2000.

Hughes, BA, Basse, L, Kim, C, Shin, DH, Eliassi-Rad, B, Nootheti, P, Chung, HS, Birt, C, and Reed, SY. Comparative study of apraclonidine 0.5% versus brimonidine 0.2% in post-argon laser trabeculoplasty intraocular pressure spike prophylaxis. ARVO Abrastracts. Invest Ophthalmol Vis Sci 41(Suppl):753, 2000.

Iezzi, R, McAlisster, P, Abrams, G, Auner, G, Johnson, R, Cortese J. A feline model for retinal stimulation and simultaneous cortical recording from multiple electrode arrays. Invest Ophthalmol Vis Sci 41(4):S9, 2000.

Iskander, NG, Penno, EEA, Peters, NT, Gimbel, HV. Discrepancies between corneal ultrasound pachymetry (DGH) and orbscan optical pachymetry measurements in primary LASIK and LASIK enhanced procedures. Proceedings, American Society of Cataract and Refractive Surgery, Symposium on Cataract, IOL and Refractive Surgery 2000, pg. 82.

Issa, SM, Weiss, JS, Tayfour, F. Ocular integrity post-LASIK. Invest Ophthalmol Vis Sci 41(S):2459, 2000.

Kataranji, S, Zwas, F, LoRusso, PM, McDermott, ML, Smith, BA, Kalemkerian, G. Electroretinographic findings in patients with long term high dose fenretinide. Invest Ophthalmol Vis Sci, 41(S):357, 2000.

Keltner, JL, Johnson,CA, Cello, KE, Quigg, JM, Kass, MA, Gordon, MO and the OHTS group. Severity of the types of visual field abnormalities in the Ocular Hypertension Treatment Study (OHTS). Invest Opthalmol Vis Sci 41(4):S84, 2000.

Kontos, AP, Eliassi-Rad, B, Shin, DH, Kim, C, Schulz, LL, Juzych, MS, Hong, YJ, and

Hughes, BA. Filtration and visual outcomes of trabeculectomy in patients with and without preoperative latanoprost. AAO Abstracts. Ophthalmology 107(Suppl):229, 2000.

Kowluru, RA. Retinal dysmetabolism continues to progress after hyperglycemia is reversed. Diabetes 49:171A, 2000.

Long, E, Dunn, D, Gordon, M, Ocular Hypertension Treatment Study (OHTS) Group. A publications and presentation policy for a multicenter clinical trial. Control Clin Trials: 21(2S): 77S, 2000.

Nootheti, P, Shin, DH, Kim, C, Morris, DA, Juzych, MS, Birt, CM, Hughes, BA, and Ren, J. Long-term outcome of cosopt replacement therapy for concomitant timolol and dorzolamide. AAO Abstracts. Ophthalmology 107(Suppl):232, 2000.

Peters, NT, Iskander, NG, Gimbel, HV. The effect of fellowship training in refractive surgery on the learning curve of laser in situ keratomileusis. Proceedings, European Society of Cataract and Refractive Surgery, p.167, 2000.

Qian, W, Shichi, H. Cataract formation by a semiquinone metabolite of acetaminophen (APAP) in mice. Invest Ophthalmol Vis Sci 41(S):211, 2000.

Qian, W, Shichi, H. Cataract formation by quinone metabolites in mice: Possible involvement of calpain activation. 5th Annual Meeting of Association for Ocular Pharmacology and Therapeutics (Nov. 2-5, 2000, Birmingham, AL) page 27, 2000.

Randant, D, Long, E, Gordon, M, the Ocular Hypertension Treatment Study (OHTS) Group. Handling forms in a multicenter clinical trial. Control Clin Trials 21(2S): 100S, 2000.

Ren, J, Nootheti, P, Shin, DH, McCarty, BD, Kim, PH, Lee, SH, and Parrow, KA. Performance in SWAP vs AAP among the eyes of ocular hypertensives and POAG patients with unilateral VF defects. Ophthalmology 107(Suppl.):229, 2000.

Shin, DH, Coleman, C, Eliassi-Rad, B, Kim, C, Juzych, MS, Nootheti ,P, Morris, DA, Bendel, RE, and Briggs, KS. Comparison of private attendings’ and residents’ glaucoma clinics with respect to patient demographics and outcomes of glaucoma management. ARVO Abstracts. Invest Ophthalmol Vis Sci 41(Suppl.):517, 2000.

Yim, H, Park, H, Shin, D, Baek, N, and Joo, C. Effect of mitomycin C trabeculectomy on lens opacity. ARVO Abstract. Invest Ophthalmol Vis Sci 41(Suppl.):512, 2000.

Allen, MY, Keole, NS, Shin, DH, Juzych, MS, Sing, MS, Parrow, KA, Swendris, RP, O’Grady, J. Comparative study of subconjunctival versus subscleral flap mitomycin C (MMC) versus no adjunctive MMC in primary glaucoma triple procedures (PTGP). Invest Ophthalmol Vis Sci (in press).

Gimbel, HV, Iskander, NG, Peters, NT, Penno, EEA. Incidence, prevention and management of LASIK complications. Ophthalmology (in press).

Peters, NT, Penno, EEA, Woods, DE, Iskander, NG, Moore, RA, Gimbel, HV. Endotoxin induced epidemic diffuse lamellar keratitis: Inflammatory potential and treatment options. Ophthalmology (in press).

Frank, RN, Grunberger, G. Cancer in a patient receiving IGF-1 therapy. Diabetes Care, 23:435, 2000.

2000 Report to Investors:
Creating Personal Partnerships

Partnerships for Life

The Quest to Improve Women's Health

Gifts from Alumni

Gifts from Faculty, Staff, Friends and Corporations

2000/2001 Alumni Annual Telefund Volunteers

2000 New Endowed Funds at the School of Medicine

Alumni Contact Information

Bibliographies:
Anatomy and Cell Biology

Barbara Ann Karmanos Cancer Institute

Biochemistry and Molecular Biology